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Showing 1 to 12 of 677 entries
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Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

diversity

Hickman MJ, Lang GI, Rice DP.
GSID: 54i6fnuak0UJ
GI Lang, DP Rice, MJ Hickman, E Sodergren… - Nature, 2013 - nature.com

The dynamics of adaptation determine which mutations fix in a population, and hence how reproducible evolution will be. This is central to understanding the spectra of mutations …

Bone mineral content has stronger association with lean mass than fat mass among Indian urban adolescents.

Indian journal of endocrinology and metabolism

Marwaha RK, Garg MK, Bhadra K, Tandon N.
PMID: 26425468
Indian J Endocrinol Metab. 2015 Sep-Oct;19(5):608-15. doi: 10.4103/2230-8210.163174.

INTRODUCTION: There are conflicting reports on the relationship of lean mass (LM) and fat mass (FM) with bone mineral content (BMC). Given the high prevalence of Vitamin D deficiency in India, we planned the study to evaluate the relationship...

Thrombosis - Besieged but Poorly Understood.

Frontiers in cardiovascular medicine

Lang IM.
PMID: 26664856
Front Cardiovasc Med. 2014 Aug 18;1:4. doi: 10.3389/fcvm.2014.00004. eCollection 2014.

No abstract available.

Comparison of body composition between professional sportswomen and apparently healthy age- and sex-matched controls.

Indian journal of endocrinology and metabolism

Marwaha RK, Garg MK, Tandon N, Mahalle N.
PMID: 25729694
Indian J Endocrinol Metab. 2015 Mar-Apr;19(2):288-91. doi: 10.4103/2230-8210.149323.

INTRODUCTION: In view of the relationship between physical activity and nutrition on body composition, we assessed lean and fat mass and BMC (total and regional) in professional Indian sportswomen and compared it with apparently healthy age- and sex-matched females.MATERIALS...

On-chip three-dimensional cell culture in phaseguides improves hepatocyte functions in vitro.

Biomicrofluidics

Jang M, Neuzil P, Volk T, Manz A, Kleber A.
PMID: 26180570
Biomicrofluidics. 2015 Jun 23;9(3):034113. doi: 10.1063/1.4922863. eCollection 2015 May.

The in vitro study of liver functions and liver cell specific responses to external stimuli deals with the problem to preserve the in vivo functions of primary hepatocytes. In this study, we used the biochip OrganoPlate(TM) (MIMETAS) that combines...

Sex differences in risk factors for subclinical hypothyroidism.

Endocrine connections

Ha J, Lee J, Jo K, Lim DJ, Kang MI, Cha BY, Kim MH.
PMID: 29514897
Endocr Connect. 2018 Apr;7(4):511-522. doi: 10.1530/EC-18-0023. Epub 2018 Mar 07.

OBJECTIVE: To investigate the prevalence of subclinical hypothyroidism (SCH) in Korean adults and identify the risk factors for the occurrence of SCH by sex.DESIGN AND METHODS: This study used data from the Sixth Korea National Health and Nutrition Examination...

Corrections to "Combined Effects of UV Exposure Duration and Mechanical Abrasion on Microplastic Fragmentation by Polymer Type".

Environmental science & technology

Song YK, Hong SH, Jang M, Han GM, Jung SW, Shim WJ.
PMID: 29485267
Environ Sci Technol. 2018 Mar 20;52(6):3831-3832. doi: 10.1021/acs.est.8b00172. Epub 2018 Feb 27.

No abstract available.

Expression and secretion of neuregulin-1 in cardiac microvascular endothelial cells treated with angiogenic factors.

Experimental and therapeutic medicine

Wu C, Gui C, Li L, Pang Y, Tang Z, Wei J.
PMID: 29545886
Exp Ther Med. 2018 Apr;15(4):3577-3581. doi: 10.3892/etm.2018.5811. Epub 2018 Jan 30.

Neuregulin-1 (NRG-1) is a positive regulator of angiogenesis, which suggests there may be an association between NRG-1 and angiogenic factors. The aim of the present study was to investigate the effect of treating human cardiac microvascular endothelial cells (HCMECs)...

Cytochrome P450 3A4*22, PPAR-α, and ARNT polymorphisms and clopidogrel response.

Clinical pharmacology : advances and applications

Kreutz RP, Owens J, Jin Y, Nystrom P, Desta Z, Kreutz Y, Breall JA, Li L, Chiang C, Kovacs RJ, Flockhart DA.
PMID: 24353446
Clin Pharmacol. 2013 Dec 09;5:185-92. doi: 10.2147/CPAA.S53151. eCollection 2013.

Recent candidate gene studies using a human liver bank and in vivo validation in healthy volunteers identified polymorphisms in cytochrome P450 (CYP) 3A4 gene (CYP3A4*22), Ah-receptor nuclear translocator (ARNT), and peroxisome proliferator-activated receptor-α (PPAR-α) genes that are associated with...

Simplified Warfarin Dose-response Pharmacodynamic Models.

Biomedical engineering : applications, basis, and communications

Kim S, Gaweda AE, Wu D, Li L, Rai SN, Brier ME.
PMID: 25750489
Biomed Eng (Singapore). 2015 Feb;27(1). doi: 10.4015/S1016237215500015.

Warfarin is a frequently used oral anticoagulant for long-term prevention and treatment of thromboembolic events. Due to its narrow therapeutic range and large inter-individual dose-response variability, it is highly desirable to personalize warfarin dosing. However, the complexity of the...

Prophylactic antibiotics for children with recurrent urinary tract infections.

Paediatrics & child health

Robinson JL, Finlay JC, Lang ME, Bortolussi R.
PMID: 25722643
Paediatr Child Health. 2015 Jan-Feb;20(1):45-51. doi: 10.1093/pch/20.1.45.

Prophylactic antibiotics for urinary tract infections are no longer routinely recommended. A large number of children must be given prophylaxis to prevent one infection and antibiotic resistance is a major concern when treating community-acquired urinary tract infections. The results...

Gold nanoflowers synthesized using Acanthopanacis cortex extract inhibit inflammatory mediators in LPS-induced RAW264.7 macrophages via NF-κB and AP-1 pathways.

Colloids and surfaces. B, Biointerfaces

Ahn S, Singh P, Jang M, Kim YJ, Castro-Aceituno V, Simu SY, Kim YJ, Yang DC.
PMID: 28985604
Colloids Surf B Biointerfaces. 2017 Dec 01;160:423-428. doi: 10.1016/j.colsurfb.2017.09.053. Epub 2017 Sep 25.

We reported the rapid synthesis (

Showing 1 to 12 of 677 entries