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Showing 1 to 12 of 243 entries
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Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

adult

Blackmore MG, Wang Z, Lerch JK.
GSID: DsN5VCMIe64J
MG Blackmore, Z Wang, JK Lerch… - Proceedings of the …, 2012 - National Acad Sciences

… Here we explore whether increasing KLF7 activity can enhance regenerative ability in the adult … Moreover, adult CST neurons fail to reexpress KLF7 after injury, and forced expression of …

Imagining the world: Conceptions and determinants of internationalization in higher education curricula worldwide

Computer and Information Science and Engineering Minority-Serving Institutions Research Expansion Program AND Program Evaluation

Lerch JC, Zapp M.
GSID: GNlQHd2mo68J
M Zapp, JC Lerch - Sociology of Education, 2020 - journals.sagepub.com

Cross-national analyses of university curricula are rare, particularly with a focus on internationalization, commonly studied as impacting higher education through the mobility of people, programs, and campuses. By contrast, we argue that university knowledge shapes globalization by producing various...

Theory testing using case studies in business-to-business research

case studies

Johnston WJ, Leach MP, Liu AH.
GSID: ZmcBP9c-MKsJ
WJ Johnston, MP Leach, AH Liu - Industrial marketing management, 1999 - Elsevier

… These three elements must be included in any confirmatory case study methodology. However, prior to dealing with any of these elements, one must adopt the idea that case studies should be evaluated as “individual studies” and not “sampling...

The trajectory of gray matter development in Broca's area is abnormal in people who stutter.

Frontiers in human neuroscience

Beal DS, Lerch JP, Cameron B, Henderson R, Gracco VL, De Nil LF.
PMID: 25784869
Front Hum Neurosci. 2015 Mar 03;9:89. doi: 10.3389/fnhum.2015.00089. eCollection 2015.

The acquisition and mastery of speech-motor control requires years of practice spanning the course of development. People who stutter often perform poorly on speech-motor tasks thereby calling into question their ability to establish the stable neural motor programs required...

Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients.

Frontiers in aging neuroscience

Kälin AM, Park MT, Chakravarty MM, Lerch JP, Michels L, Schroeder C, Broicher SD, Kollias S, Nitsch RM, Gietl AF, Unschuld PG, Hock C, Leh SE.
PMID: 28326033
Front Aging Neurosci. 2017 Mar 07;9:38. doi: 10.3389/fnagi.2017.00038. eCollection 2017.

Efficacy of future treatments depends on biomarkers identifying patients with mild cognitive impairment at highest risk for transitioning to Alzheimer's disease. Here, we applied recently developed analysis techniques to investigate cross-sectional differences in subcortical shape and volume alterations in...

Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design.

Frontiers in immunology

Brown AF, Leech JM, Rogers TR, McLoughlin RM.
PMID: 24409186
Front Immunol. 2014 Jan 08;4:507. doi: 10.3389/fimmu.2013.00507.

In apparent contrast to its invasive potential Staphylococcus aureus colonizes the anterior nares of 20-80% of the human population. The relationship between host and microbe appears particularly individualized and colonization status seems somehow predetermined. After decolonization, persistent carriers often...

Personality disorder symptomatology is associated with anomalies in striatal and prefrontal morphology.

Frontiers in human neuroscience

Payer DE, Park MT, Kish SJ, Kolla NJ, Lerch JP, Boileau I, Chakravarty MM.
PMID: 26379535
Front Hum Neurosci. 2015 Aug 31;9:472. doi: 10.3389/fnhum.2015.00472. eCollection 2015.

Personality disorder symptomatology (PD-Sx) can result in personal distress and impaired interpersonal functioning, even in the absence of a clinical diagnosis, and is frequently comorbid with psychiatric disorders such as substance use, mood, and anxiety disorders; however, they often...

Self-Healing of Core-Shell Magnetic Polystyrene Nanocomposites.

ACS applied materials & interfaces

Yoonessi M, Lerch BA, Peck JA, Rogers RB, Solá-Lopez FJ, Meador MA.
PMID: 26192341
ACS Appl Mater Interfaces. 2015 Aug 12;7(31):16932-7. doi: 10.1021/acsami.5b04314. Epub 2015 Jul 31.

High heat generation is reported in core-shell magnetic nanoparticle polystyrene (PS) nanocomposites (3.5, 10 wt %) when they are placed in a high-frequency ac magnetic field. These magnetic nanoparticles with cobalt iron oxide core and manganese iron oxide shell...

Monostatic all-fiber scanning LADAR system.

Applied optics

Leach JH, Chinn SR, Goldberg L.
PMID: 26836533
Appl Opt. 2015 Nov 20;54(33):9752-7. doi: 10.1364/AO.54.009752.

A compact scanning LADAR system based on a fiber-coupled, monostatic configuration which transmits (TX) and receives (RX) through the same aperture has been developed. A small piezo-electric stripe actuator was used to resonantly vibrate a fiber cantilever tip and...

Ceramic identity contributes to mechanical properties and osteoblast behavior on macroporous composite scaffolds.

Journal of functional biomaterials

Morales-Hernandez DG, Genetos DC, Working DM, Murphy KC, Leach JK.
PMID: 24955539
J Funct Biomater. 2012 May 23;3(2):382-97. doi: 10.3390/jfb3020382.

Implants formed of metals, bioceramics, or polymers may provide an alternative to autografts for treating large bone defects. However, limitations to each material motivate the examination of composites to capitalize on the beneficial aspects of individual components and to...

Solute diffusion and interactions in cross-linked poly(ethylene glycol) hydrogels studied by Fluorescence Correlation Spectroscopy.

Soft matter

Zustiak SP, Boukari H, Leach JB.
PMID: 24282439
Soft Matter. 2010 Aug 07;6(15). doi: 10.1039/C0SM00111B.

Controlled diffusion and release of soluble molecules is one of the key challenges in developing three-dimensional (3D) scaffolds for tissue engineering and drug delivery applications in part because current methods to measure dynamic transport properties are difficult to perform...

The Symmetry of the Internal Ears in Flatfishes.

Proceedings of the National Academy of Sciences of the United States of America

Leech JV.
PMID: 16576720
Proc Natl Acad Sci U S A. 1923 Aug;9(8):286-8. doi: 10.1073/pnas.9.8.286.

No abstract available.

Showing 1 to 12 of 243 entries