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Showing 1 to 12 of 377 entries
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Past, present, and future of hormonal therapy in recurrent endometrial cancer.

International journal of women's health

Carlson MJ, Thiel KW, Leslie KK.
PMID: 24833920
Int J Womens Health. 2014 May 02;6:429-35. doi: 10.2147/IJWH.S40942. eCollection 2014.

Endometrial cancer is a heterogeneous disease. Type I cancers are hormonally driven, typically present with a low grade at an early stage, and are of endometrioid histology. These cancers are often cured by surgery, and the rate of recurrence...

Absolute Differential Positronium-Formation Cross Sections.

Physical review letters

Shipman M, Armitage S, Beale J, Brawley SJ, Fayer SE, Garner AJ, Leslie DE, Van Reeth P, Laricchia G.
PMID: 26230792
Phys Rev Lett. 2015 Jul 17;115(3):033401. doi: 10.1103/PhysRevLett.115.033401. Epub 2015 Jul 14.

The first absolute experimental determinations of the differential cross sections for the formation of ground-state positronium are presented for He, Ar, H2, and CO2 near 0°. Results are compared with available theories. The ratio of the differential and integrated...

YeATS - a tool suite for analyzing RNA-seq derived transcriptome identifies a highly transcribed putative extensin in heartwood/sapwood transition zone in black walnut.

F1000Research

Chakraborty S, Britton M, Wegrzyn J, Butterfield T, Rao BJ, Leslie CA, Aradhaya M, Neale D, Woeste K, Dandekar AM.
PMID: 26870317
F1000Res. 2015 Jun 17;4:155. doi: 10.12688/f1000research.6617.1. eCollection 2015.

The transcriptome provides a functional footprint of the genome by enumerating the molecular components of cells and tissues. The field of transcript discovery has been revolutionized through high-throughput mRNA sequencing (RNA-seq). Here, we present a methodology that replicates and...

Fasting, translation control, and seizures.

Science signaling

Ferrarelli LK.
PMID: 28049769
Sci Signal. 2017 Jan 03;10(460). doi: 10.1126/scisignal.aam6552.

No abstract available.

A nap a day keeps the pain away?.

Science signaling

Ferrarelli LK.
PMID: 28655856
Sci Signal. 2017 Jun 27;10(485). doi: 10.1126/scisignal.aao1782.

Getting more sleep or increasing caffeine intake during the day may relieve chronic pain better than typical pain-killers.

Evaluating the impact of a resident research program in general surgery.

Canadian medical education journal

Allen L, Vogt K, Mele T, Ott M, Leslie K, Colquhoun P.
PMID: 29098044
Can Med Educ J. 2017 Jun 30;8(3):e13-e20. eCollection 2017 Jun.

BACKGROUND: Programs of resident research have been found to improve research productivity. However, evidence of the success of these programs is lacking in a Canadian context. The objective of this study was to evaluate the impact of the introduction...

In Situ Dark Adaptation Enhances the Efficiency of DNA Extraction from Mature Pin Oak (Quercus palustris) Leaves, Facilitating the Identification of Partial Sequences of the 18S rRNA and Isoprene Synthase (IspS) Genes.

Plants (Basel, Switzerland)

Barta CE, Bolander B, Bilby SR, Brown JH, Brown RN, Duryee AM, Edelman DR, Gray CE, Gossett C, Haddock AG, Helsel MM, Jones AD, Klingseis ME, Leslie K, Miles EW, Prawitz RA.
PMID: 29073736
Plants (Basel). 2017 Oct 24;6(4). doi: 10.3390/plants6040052.

Mature oak (

Something's missing from my education: Using a cross sectional survey to examine the needs and interest of Canadian medical students relating to their roles as teachers and educators.

Canadian medical education journal

Nagji A, Leslie K, Wong E, Myhre D, Young M, Chan MK.
PMID: 29098045
Can Med Educ J. 2017 Jun 30;8(3):e21-e29. eCollection 2017 Jun.

BACKGROUND: Current theory in medical education emphasizes engaging learners as educators while tailoring teaching to their learning needs. However, little is known about learners' perceptions of their proposed roles as teachers and educators.METHODS: Canadian medical students were invited to...

Creating a weakness in prostate cancer.

Science (New York, N.Y.)

Ferrarelli LK.
PMID: 28546198
Science. 2017 May 26;356(6340):816-818. doi: 10.1126/science.356.6340.816-o.

No abstract available.

miR-888: A Novel Cancer-Testis Antigen that Targets the Progesterone Receptor in Endometrial Cancer.

Translational oncology

Hovey AM, Devor EJ, Breheny PJ, Mott SL, Dai D, Thiel KW, Leslie KK.
PMID: 25926074
Transl Oncol. 2015 Apr;8(2):85-96. doi: 10.1016/j.tranon.2015.02.001.

Cancer-testis (CT) antigens are a large family of genes that are selectively expressed in human testis germ cells, overexpressed in a variety of tumors and predominantly located on the X chromosome. To date, all known CT antigens are protein-coding...

Affinity regression predicts the recognition code of nucleic acid-binding proteins.

Nature biotechnology

Pelossof R, Singh I, Yang JL, Weirauch MT, Hughes TR, Leslie CS.
PMID: 26571099
Nat Biotechnol. 2015 Dec;33(12):1242-1249. doi: 10.1038/nbt.3343. Epub 2015 Nov 16.

Predicting the affinity profiles of nucleic acid-binding proteins directly from the protein sequence is a challenging problem. We present a statistical approach for learning the recognition code of a family of transcription factors or RNA-binding proteins (RBPs) from high-throughput...

Strategies for Molecularly Enhanced Chemotherapy to Achieve Synthetic Lethality in Endometrial Tumors with Mutant p53.

Obstetrics and gynecology international

Meng X, Dizon DS, Yang S, Wang X, Zhu D, Thiel KW, Leslie KK.
PMID: 24381593
Obstet Gynecol Int. 2013;2013:828165. doi: 10.1155/2013/828165. Epub 2013 Dec 07.

Serous uterine endometrial carcinomas are aggressive type II cancers with poor outcomes for which new treatment strategies are urgently needed, in particular, strategies that augment sensitivity to established chemotherapy regimens. The tumor suppressor gene TP53 is dysregulated in more...

Showing 1 to 12 of 377 entries