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Showing 1 to 12 of 187 entries
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Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development.

Cancer cell

Pichiorri F, Suh SS, Rocci A, De Luca L, Taccioli C, Santhanam R, Zhou W, Benson DM, Hofmainster C, Alder H, Garofalo M, Di Leva G, Volinia S, Lin HJ, Perrotti D, Kuehl M, Aqeilan RI, Palumbo A, Croce CM.
PMID: 27505674
Cancer Cell. 2016 Aug 08;30(2):349-351. doi: 10.1016/j.ccell.2016.07.007. Epub 2016 Aug 08.

No abstract available.

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer.

Hormone molecular biology and clinical investigation

Clarke R, Shajahan AN, Wang Y, Tyson JJ, Riggins RB, Weiner LM, Bauman WT, Xuan J, Zhang B, Facey C, Aiyer H, Cook K, Hickman FE, Tavassoly I, Verdugo A, Chen C, Zwart A, Wärri A, Hilakivi-Clarke LA.
PMID: 23930139
Horm Mol Biol Clin Investig. 2011 Mar;5(1):35-44. doi: 10.1515/hmbci.2010.073.

Lack of understanding of endocrine resistance remains one of the major challenges for breast cancer researchers, clinicians, and patients. Current reductionist approaches to understanding the molecular signaling driving resistance have offered mostly incremental progress over the past 10 years....

Evaluate the Malocclusion in Subjects Reporting for Orthodontic Treatment among Saudi Population in Asser Region.

Journal of international oral health : JIOH

AlQarni MA, Banihuwaiz AH, Alshehri FD, Alqarni AS, Alasmari DS.
PMID: 25214731
J Int Oral Health. 2014 Jul;6(4):42-6.

BACKGROUND: Oral health is an important component of general health and is associated with the development of a healthy personality. The malocclusion has been shown to affects oral health, leads to increased prevalence of dental caries and may result...

Understanding the Mechanism of Cell Death in Gemcitabine Resistant Pancreatic Ductal Adenocarcinoma: A Systems Biology Approach.

Current genomics

Aier I, Varadwaj PK.
PMID: 32655287
Curr Genomics. 2019 Nov;20(7):483-490. doi: 10.2174/1389202920666191025102726.

BACKGROUND: Gemcitabine is the standard chemotherapeutic drug administered in advanced Pancreatic Ductal Adenocarcinoma (PDAC). However, due to drug resistance in PDAC patients, this treatment has become less effective. Over the years, clinical trials for the quest of finding novel...

Prevalence and determinants of oral potentially malignant lesions using mobile health in a rural block, northeast India.

Tropical doctor

Ramesh RM, Patrick S, Lotha Z, Azole, Aier A, Birur N P.
PMID: 34791946
Trop Doct. 2021 Nov 18;494755211049973. doi: 10.1177/00494755211049973. Epub 2021 Nov 18.

In a rural block in North East India, community health workers (CHW) empowered with a mobile phone-based application screened a total of 2,686 participants for Oral Potentially Malignant Lesions (OPMLs), and an oral medicine specialist recommended treatment remotely. Independent...

Active methamphetamine use is associated with transmitted drug resistance to non-nucleoside reverse transcriptase inhibitors in individuals with HIV infection of unknown duration.

The open AIDS journal

Cachay ER, Moini N, Kosakovsky Pond SL, Pesano R, Lie YS, Aiem H, Butler DM, Letendre S, Mathews WC, Smith DM.
PMID: 18923691
Open AIDS J. 2007;1:5-10. doi: 10.2174/1874613600701010005. Epub 2007 Oct 22.

BACKGROUND: Frequent methamphetamine use among recently HIV infected individuals is associated with transmitted drug resistance (TDR) to non-nucleoside reverse transcriptase inhibitors (NNRTI); however, the reversion time of TDR to drug susceptible HIV may exceed 3 years. We assessed whether...

Unravelling the role of long non-coding RNA - .

Non-coding RNA research

Tripathi R, Aier I, Chakraborty P, Varadwaj PK.
PMID: 31989062
Noncoding RNA Res. 2019 Dec 24;5(1):1-10. doi: 10.1016/j.ncrna.2019.12.002. eCollection 2020 Mar.

Apoptosis is a 'programmed fate' of all cells participating in diverse physiological and pathological conditions. The role of critical regulators and their involvement in this complex multi-stage process of apoptosis weaved around non-coding RNAs (ncRNAs) is poorly deciphered in...

DeepOlf: Deep neural network based architecture for predicting odorants and their interacting Olfactory Receptors.

IEEE/ACM transactions on computational biology and bioinformatics

Sharma A, Kumar R, Semwal R, Aier I, Tyagi P, Varadwaj P.
PMID: 32750862
IEEE/ACM Trans Comput Biol Bioinform. 2020 Jun 12; doi: 10.1109/TCBB.2020.3002154. Epub 2020 Jun 12.

Olfaction transduction mechanism is triggered by the binding of odorants to the specific olfactory receptors (OR's) present in the nasal cavity. Different odorants stimulate different OR's due to the difference in shape, physical and chemical properties. In this paper,...

Complete Genome Sequences of .

Microbiology resource announcements

Alder H, Himelright M, Eisemann E, Temple L.
PMID: 30938704
Microbiol Resour Announc. 2019 Mar 21;8(12). doi: 10.1128/MRA.01103-18.

Wes44 and Carmen17 are siphoviruses that infect

Twelve tips for using ePosters as an active learning strategy.

Medical teacher

Premkumar K, Othman I, Aiyer H.
PMID: 34689694
Med Teach. 2021 Oct 24;1-8. doi: 10.1080/0142159X.2021.1966402. Epub 2021 Oct 24.

ePosters (electronic Posters), a modification of traditional paper-based posters have gained popularity in medical education conferences since 2011. ePoster in educational settings differs from the traditional poster in that it allows the ePoster creator to focus on the learning...

Psychosocial aspects of children with chronic kidney disease and their families.

Clinical and experimental pediatrics

Aier A, Pais P, Raman V.
PMID: 34773940
Clin Exp Pediatr. 2021 Nov 10; doi: 10.3345/cep.2021.01004. Epub 2021 Nov 10.

Pediatric chronic kidney disease (CKD) is a chronic illness that affects the overall quality of life of patients during childhood. This article highlights the psychological and social burden of CKD in patients and their families. Patients with CKD and...

Child alcohol use disorder in Eastern Uganda: screening, diagnostics, risk factors and management of children drinking alcohol in Uganda (TREAT C-AUD): a mixed-methods research protocol.

BMJ paediatrics open

Skylstad V, Aber H, Bakken V, Dierkes J, Iversen SA, Kisaakye E, Kühl MJ, Nalugya JS, Rayamajhi D, Sebuwufu D, Skar AS, Skokauskas N, Valeckaite N, Wamani H, S Engebretsen IM, Babirye JN.
PMID: 34345718
BMJ Paediatr Open. 2021 Jul 28;5(1):e001214. doi: 10.1136/bmjpo-2021-001214. eCollection 2021.

BACKGROUND: Following a finding of alcohol use among children aged 5-8 years old in Mbale, Uganda, this project investigates the magnitude of alcohol and substance use among children ged 6-13 years old and related household, community, school, health system...

Showing 1 to 12 of 187 entries