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Showing 1 to 12 of 91 entries
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AuthorBase: a database of authoring systems software.

Proceedings. Symposium on Computer Applications in Medical Care

Lo R, Locatis C, Ullmer E, Carr V, Banvard R, Le Q, Williamson M, Ackerman M.
PMID: 1807735
Proc Annu Symp Comput Appl Med Care. 1991;875-6.
Free PMC Article

A working prototype database of authoring system software was developed as part of a study of authoring software conducted by the National Library of Medicine. The database and development issues ranging from the scope of the database to what...

Clinical Relevance Of Systematic CRT Device Optimization.

Journal of atrial fibrillation

Lunati M, Magenta G, Cattafi G, Moreo A, Falaschi G, Contardi D, Locati E.
PMID: 27957096
J Atr Fibrillation. 2014 Aug 31;7(2):1077. doi: 10.4022/jafib.1077. eCollection 2014.

Cardiac Resynchronization Therapy (CRT) is known as a highly effective therapy in advanced heart failure patients with cardiac dyssynchrony. However, still one third of patients do not respond (or sub-optimally respond) to CRT. Among the many contributors for the...

Atypical chemokine receptor 2: a brake against Kaposi's sarcoma aggressiveness.

Oncoimmunology

Bonecchi R, Savino B, Caronni N, Celesti G, Mantovani A, Locati M.
PMID: 25964861
Oncoimmunology. 2015 Jan 07;3(12):e955337. doi: 10.4161/21624011.2014.955337. eCollection 2014 Dec.

Inflammatory chemokines are instrumental players in cancer-related inflammation contributing to numerous steps during tumor progression. In Kaposi's sarcoma, we have found that downregulation of the atypical chemokine receptor 2 (ACKR2) by the KRAS/BRAF/ERK pathway profoundly affects the tumor microenvironment,...

Allosteric Modulation of Chemoattractant Receptors.

Frontiers in immunology

Allegretti M, Cesta MC, Locati M.
PMID: 27199992
Front Immunol. 2016 May 02;7:170. doi: 10.3389/fimmu.2016.00170. eCollection 2016.

Chemoattractants control selective leukocyte homing via interactions with a dedicated family of related G protein-coupled receptor (GPCR). Emerging evidence indicates that the signaling activity of these receptors, as for other GPCR, is influenced by allosteric modulators, which interact with...

Extending a Blended Education Program to Native American High School Students in Alaska.

Journal of visual communication in medicine

Locatis C, Gaines C, Liu WL, Gill M.
PMID: 21494418
J Vis Commun Med. 2009 Jan;32(1):8-13. doi: 10.1080/17453050902821181.

This article describes the expansion of a blended learning program sponsored by the National Library of Medicine (NLM) that combines synchronous distance learning with face to face instruction. Background information about the program is briefly discussed and challenges to...

New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM.

Vaccines

Scala S, D'Alterio C, Milanesi S, Castagna A, Carriero R, Farina FM, Locati M, Borroni EM.
PMID: 32260318
Vaccines (Basel). 2020 Apr 03;8(2). doi: 10.3390/vaccines8020164.

Deciphering the molecular alterations leading to disease initiation and progression is currently crucial to identify the most relevant targets for precision therapy in cancer patients. Cancers express a complex chemokine network influencing leucocyte infiltration and angiogenesis. Moreover, malignant cells...

Dermatomyositis- Related Intestinal Dysmotility.

Modern rheumatology case reports

Loftis C, White R, Dulgheru EC.
PMID: 34791372
Mod Rheumatol Case Rep. 2021 Nov 17; doi: 10.1093/mrcr/rxab043. Epub 2021 Nov 17.

Dermatomyositis (DM) is an inflammatory myopathy characterized by proximal muscle weakness and pathognomonic skin lesions. A 69-year-old woman with a recent diagnosis of DM one month prior, treated with corticosteroids and immunomodulators, presented to our inpatient rehabilitation with worsening...

Please mind the gap-about equity and access to care in oncology.

ESMO open

Barcellini A, Dal Mas F, Paoloni P, Loap P, Cobianchi L, Locati L, Rodríguez-Luna MR, Orlandi E.
PMID: 34902710
ESMO Open. 2021 Dec 10;6(6):100335. doi: 10.1016/j.esmoop.2021.100335. Epub 2021 Dec 10.

No abstract available.

ERα-independent NRF2-mediated immunoregulatory activity of tamoxifen.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Pepe G, Sfogliarini C, Rizzello L, Battaglia G, Pinna C, Rovati G, Ciana P, Brunialti E, Mornata F, Maggi A, Locati M, Vegeto E.
PMID: 34653752
Biomed Pharmacother. 2021 Dec;144:112274. doi: 10.1016/j.biopha.2021.112274. Epub 2021 Oct 12.

Sex differences in immune-mediated diseases are linked to the activity of estrogens on innate immunity cells, including macrophages. Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM) used in estrogen receptor-alpha (ERα)-dependent breast cancers and off-target indications such as...

Survival Outcomes After Immediate Radical Cystectomy Versus Conservative Management with Bacillus Calmette-Guérin Among T1 High-grade Micropapillary Bladder Cancer Patients: Results from a Multicentre Collaboration.

European urology focus

Lonati C, Baumeister P, Afferi L, Mari A, Minervini A, Krajewski W, Azizi S, Hendricksen K, Martini A, Necchi A, Montorsi F, Briganti A, Colombo R, Tafuri A, Antonelli A, Cerruto MA, Rouprêt M, Masson-Lecomte A, Laukhtina E, D'Andrea D, Shariat SF, Soria F, Marra G, Gontero P, Contieri R, Hurle R, Valiquette AS, Mir MC, Zamboni S, Simeone C, Klatte T, Teoh JY, Yoshida S, Fujii Y, Carando R, Schulz GB, Mordasini L, Mattei A, Moschini M.
PMID: 34419381
Eur Urol Focus. 2021 Aug 18; doi: 10.1016/j.euf.2021.07.015. Epub 2021 Aug 18.

BACKGROUND: Literature lacks clear evidence regarding the optimal treatment for non-muscle-invasive micropapillary bladder cancer (MPBC) due to its rarity and the presence of only small sample size and single-centre studies.OBJECTIVE: To assess cancer-specific mortality (CSM) and overall mortality (OM)...

The Impact of Diagnostic Ureteroscopy Prior to Radical Nephroureterectomy on Oncological Outcomes in Patients with Upper Tract Urothelial Carcinoma: A Comprehensive Systematic Review and Meta-Analysis.

Journal of clinical medicine

Nowak Ł, Krajewski W, Chorbińska J, Kiełb P, Sut M, Moschini M, Teoh JY, Mori K, Del Giudice F, Laukhtina E, Lonati C, Kaliszewski K, Małkiewicz B, Szydełko T.
PMID: 34575307
J Clin Med. 2021 Sep 16;10(18). doi: 10.3390/jcm10184197.

BACKGROUND: The incidence of intravesical recurrence (IVR) following radical nephroureterectomy (RNU) is reported in up to 50% of patients with upper tract urothelial carcinoma (UTUC). It was suggested that preoperative diagnostic ureteroscopy (URS) could increase the IVR rate after...

The Hierarchy-of-Hypotheses Approach: A Synthesis Method for Enhancing Theory Development in Ecology and Evolution.

Bioscience

Heger T, Aguilar-Trigueros CA, Bartram I, Braga RR, Dietl GP, Enders M, Gibson DJ, Gómez-Aparicio L, Gras P, Jax K, Lokatis S, Lortie CJ, Mupepele AC, Schindler S, Starrfelt J, Synodinos AD, Jeschke JM.
PMID: 33867867
Bioscience. 2020 Dec 02;71(4):337-349. doi: 10.1093/biosci/biaa130. eCollection 2021 Apr.

In the current era of Big Data, existing synthesis tools such as formal meta-analyses are critical means to handle the deluge of information. However, there is a need for complementary tools that help to (a) organize evidence, (b) organize...

Showing 1 to 12 of 91 entries