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Showing 1 to 12 of 108 entries
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Cryptococcal 3-Hydroxy Fatty Acids Protect Cells Against Amoebal Phagocytosis.

Frontiers in microbiology

Madu UL, Ogundeji AO, Mochochoko BM, Pohl CH, Albertyn J, Swart CW, Allwood JW, Southam AD, Dunn WB, May RC, Sebolai OM.
PMID: 26696972
Front Microbiol. 2015 Dec 09;6:1351. doi: 10.3389/fmicb.2015.01351. eCollection 2015.

We previously reported on a 3-hydroxy fatty acid that is secreted via cryptococcal capsular protuberances - possibly to promote pathogenesis and survival. Thus, we investigated the role of this molecule in mediating the fate of Cryptococcus (C.) neoformans and...

Molecular docking analysis of aplysin analogs targeting survivin protein.

Bioinformation

Shakeel E, Akhtar S, Khan MKA, Lohani M, Arif JM, Siddiqui MH.
PMID: 29081608
Bioinformation. 2017 Sep 30;13(9):293-300. doi: 10.6026/97320630013293. eCollection 2017.

Survivin (IAP proteins) remains an important target for anticancer drug development as it is reported to be over-expressed in tumor cells to enhance resistance to apoptotic stimuli. The study focuses on virtual screening of marine compounds inhibiting survivin, a...

Rapid, sensitive, type specific PCR detection of the E7 region of human papillomavirus type 16 and 18 from paraffin embedded sections of cervical carcinoma.

Infectious agents and cancer

Lesnikova I, Lidang M, Hamilton-Dutoit S, Koch J.
PMID: 20180999
Infect Agent Cancer. 2010 Jan 22;5:2. doi: 10.1186/1750-9378-5-2.

Human papillomavirus (HPV) infection, and in particularly infection with HPVs 16 and 18, is a central carcinogenic factor in the uterine cervix. We established and optimized a PCR assay for the detection and discrimination of HPV types 16 and...

p16 as a diagnostic marker of cervical neoplasia: a tissue microarray study of 796 archival specimens.

Diagnostic pathology

Lesnikova I, Lidang M, Hamilton-Dutoit S, Koch J.
PMID: 19589135
Diagn Pathol. 2009 Jul 09;4:22. doi: 10.1186/1746-1596-4-22.

BACKGROUND: To evaluate the usefulness of this biomarker in the diagnosis of cases of cervical neoplasia we studied the immunohistochemical expression of p16INK4a in a large series of archival cervical biopsies arranged into tissue microarray format.METHODS: TMAs were constructed...

Assessment of procalcitonin to predict outcome in hypothermia-treated patients after cardiac arrest.

Critical care research and practice

Stammet P, Devaux Y, Azuaje F, Werer C, Lorang C, Gilson G, Max M.
PMID: 22110909
Crit Care Res Pract. 2011;2011:631062. doi: 10.1155/2011/631062. Epub 2011 Oct 26.

Objective. Determine the potential of procalcitonin (PCT) to predict neurological outcome after hypothermia treatment following cardiac arrest. Methods. Retrospective analysis of patient data over a 2-year period. Mortality and neurological outcome of survivors were determined 6 months after cardiac...

Molecular Docking of Known Carcinogen 4- (Methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) with Cyclin Dependent Kinases towards Its Potential Role in Cell Cycle Perturbation.

Bioinformation

Haneef M, Lohani M, Dhasmana A, Jamal QM, Shahid SM, Firdaus S.
PMID: 25258489
Bioinformation. 2014 Aug 30;10(8):526-32. doi: 10.6026/97320630010526. eCollection 2014.

Cell cycle is maintained almost all the times and is controlled by various regulatory proteins and their complexes (Cdk+Cyclin) in different phases of interphase (G1, S and G2) and mitosis of cell cycle. A number of mechanisms have been...

Author Correction: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.

Nature

Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR.
PMID: 29950716
Nature. 2018 Jul;559(7715):E11. doi: 10.1038/s41586-018-0230-z.

In this Letter, the sentence beginning "This work was funded…." in the Acknowledgements should have read "CPRIT (RP140105) to J.C.R." rather than "CPRIT (RP150445) to J.C.R." This error has been corrected online.

Power Profiling, Workload Characteristics, and Race Performance of U23 and Professional Cyclists During the Multistage Race Tour of the Alps.

International journal of sports physiology and performance

Leo P, Spragg J, Mujika I, Giorgi A, Lorang D, Simon D, Lawley JS.
PMID: 33789246
Int J Sports Physiol Perform. 2021 Mar 31;1-7. doi: 10.1123/ijspp.2020-0381. Epub 2021 Mar 31.

PURPOSE: The aim of this study was to compare the power profile, internal and external workloads, and racing performance between U23 and professional cyclists and between varying rider types across 2 editions of a professional multistage race.METHODS: Nine U23...

Accuracy of Resolution of ST-Segment Elevation in Electrocardiogram to Determine the Patency of Infarct-Related Artery.

Cureus

Shaikh MK, Ali Shah SZ, Kumar C, Lohano M, Talpur AS, Zahoor A, Kumar V, Kumar B.
PMID: 34079653
Cureus. 2021 Apr 13;13(4):e14448. doi: 10.7759/cureus.14448.

INTRODUCTION:  There is very limited data comparing the accuracy of ECG to angiography in predicting reperfusion status. In this study, we will determine the accuracy of ECG change i.e. resolution of ST-segment elevation in predicting infarct-related artery (IRA) patency...

Avocado/soy unsaponifiables can redress the balance between serum antioxidant and oxidant levels in patients with osteoarthritis: a double-blind, randomized, placebo-controlled, cross-over study.

Journal of complementary & integrative medicine

Jangravi Z, Basereh S, Zaree Mahmoudabadi A, Saberi M, Alishiri GH, Korani M.
PMID: 33794080
J Complement Integr Med. 2021 Apr 02;18(4):769-774. doi: 10.1515/jcim-2020-0265.

OBJECTIVES: Osteoarthritis (OA) is an inflammatory disorder of the joint characterized by pain and stiffness. Oxidative stress plays an important role in pathogenesis of OA. We aimed to evaluate the effects of avocado/soy unsaponifiables (ASU) compound on serum antioxidant...

Mouse Organ-Specific Proteins and Functions.

Cells

Sun B, Lorang C, Qin S, Zhang Y, Liu K, Li G, Sun Z, Francke A, Utleg AG, Hu Z, Wang K, Moritz RL, Hood L.
PMID: 34943957
Cells. 2021 Dec 08;10(12). doi: 10.3390/cells10123449.

Organ-specific proteins (OSPs) possess great medical potential both in clinics and in biomedical research. Applications of them-such as alanine transaminase, aspartate transaminase, and troponins-in clinics have raised certain concerns of their organ specificity. The dynamics and diversity of protein...

Influence of Organized vs Non Organized Physical Activity on School Adaptation Behavior.

Frontiers in psychology

Alexandru MA, Jürgen B, Arash M, Guillaume M, Lorand B.
PMID: 33329181
Front Psychol. 2020 Nov 19;11:550952. doi: 10.3389/fpsyg.2020.550952. eCollection 2020.

It is now well-established that physical activity has positive effects on both physical and mental health. However, the influence of organized physical activity (i.e., programs controlled and supervised by a trainer) on school adaptive behavior of adolescents with disabilities...

Showing 1 to 12 of 108 entries