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Showing 1 to 12 of 135 entries
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Co-designing Research Methods Lesson Plans in the Interactive Research Methods Lab

lesson plans

Abellán IMJ, Vasquez A, Gaines RE.
GSID: oMzGAmZEix8J
IMJ Abellán, A Vasquez, RE Gaines - Edutec. Revista Electrónica De …, 2020 - edutec.es

… In this paper we have presented five co-design sessions aimed at developing research methods lesson plans for undergraduate and … Our findings evidence that the co-designed lesson plans implemented in the IRML offer an alternative approach for teaching...

Palatal fistula risk after primary palatoplasty: a retrospective comparison of humanitarian operations and tertiary hospitals.

Lancet (London, England)

Daniels KM, Yu EY, Maine RG, Corlew S, Bing S, Hoffman WY, Gregory GA.
PMID: 26313085
Lancet. 2015 Apr 27;385:S37. doi: 10.1016/S0140-6736(15)60832-7. Epub 2015 Apr 26.

BACKGROUND: Humanitarian surgical organisations provide cleft palate repair for patients without access to surgical care. Despite decades of experience, very little research has assessed the outcomes of these trips. This study investigates the fistula rate in patients from two...

Analysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis System.

Frontiers in behavioral neuroscience

Bains RS, Cater HL, Sillito RR, Chartsias A, Sneddon D, Concas D, Keskivali-Bond P, Lukins TC, Wells S, Acevedo Arozena A, Nolan PM, Armstrong JD.
PMID: 27375446
Front Behav Neurosci. 2016 Jun 10;10:106. doi: 10.3389/fnbeh.2016.00106. eCollection 2016.

Central nervous system disorders such as autism as well as the range of neurodegenerative diseases such as Huntington's disease are commonly investigated using genetically altered mouse models. The current system for characterizing these mice usually involves removing the animals...

The Toxicity and Benefit of Various Dosing Strategies for Interleukin-2 in Metastatic Melanoma and Renal Cell Carcinoma.

Journal of the advanced practitioner in oncology

Pachella LA, Madsen LT, Dains JE.
PMID: 26557408
J Adv Pract Oncol. 2015 May-Jun;6(3):212-21. Epub 2015 May 01.

Interleukin-2 (IL-2) therapy has been used with success in curing meta-static renal cell carcinoma and melanoma in a small minority of patients. However, the benefits can be accompanied by severe toxicity. This review of the literature discusses varying doses...

Hormone Replacement Therapy: An Increased Risk of Recurrence and Mortality for Breast Cancer Patients?.

Journal of the advanced practitioner in oncology

Lupo M, Dains JE, Madsen LT.
PMID: 26705493
J Adv Pract Oncol. 2015 Jul-Aug;6(4):322-30. doi: 10.6004/jadpro.2015.6.4.3. Epub 2015 Jul 01.

Historically, randomized controlled trials (RCTs) have shown an increased risk of recurrence and mortality among women who have used primarily oral HRT after breast cancer. However, many of these studies have had design flaws that may impact the findings....

High-dynamic-range arrival time control for flexible, accurate and precise parametric sub-cycle waveform synthesis.

Optics express

Mainz RE, Rossi GM, Cirmi G, Yang Y, Mücke OD, Kärtner FX.
PMID: 28241522
Opt Express. 2017 Feb 20;25(4):3052-3068. doi: 10.1364/OE.25.003052.

We introduce a simple all-inline variation of a balanced optical cross-correlator (BOC) that allows to measure the arrival time difference (ATD), over the full Nyquist bandwidth, with increased common-mode rejection and long-term stability. An FPGA-based signal processing unit allows...

Targeting Radiotherapy to Cancer by Gene Transfer.

Journal of biomedicine & biotechnology

Mairs RJ, Boyd M.
PMID: 12721515
J Biomed Biotechnol. 2003;2003(2):102-109. doi: 10.1155/S1110724303209062.

Targeted radionuclide therapy is an alternative method of radiation treatment which uses a tumor-seeking agent carrying a radioactive atom to deposits of tumor, wherever in the body they may be located. Recent experimental data signifies promise for the amalgamation...

5-amino-salicylate in the management of inflammatory bowel disease.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Makins RJ, Cowan RE.
PMID: 12790962
Colorectal Dis. 2001 Jul;3(4):218-22. doi: 10.1046/j.1463-1318.2001.00265.x.

The role of aminosalicylates in the treatment of idiopathic bowel disease is reviewed, with emphasis on how the different formulations can be used in different clinical manifestations. Although not fully understood, the possible mechanisms of action of these agents...

Chemistry in china.

Science (New York, N.Y.)

Cairns RE.
PMID: 17799641
Science. 1979 Dec 14;206(4424):1296-8. doi: 10.1126/science.206.4424.1296-a.

No abstract available.

Differential regulation of neuropeptide Y and catecholamine production in superior cervical ganglion cultures.

Molecular and cellular neurosciences

Marek KL, Mains RE.
PMID: 19912776
Mol Cell Neurosci. 1990 Dec;1(3):262-9. doi: 10.1016/1044-7431(90)90008-r.

Primary cultures of newborn rat superior cervical ganglion (SCG) neurons grown in complete serum-free medium have been used to study the regulation of catecholamine and neuropeptide Y (NPY) production. The levels of mRNA for preproNPY and for tyrosine hydroxylase...

Role of adaptor proteins in secretory granule biogenesis and maturation.

Frontiers in endocrinology

Bonnemaison ML, Eipper BA, Mains RE.
PMID: 23966980
Front Endocrinol (Lausanne). 2013 Aug 14;4:101. doi: 10.3389/fendo.2013.00101. eCollection 2013.

In the regulated secretory pathway, secretory granules (SGs) store peptide hormones that are released on demand. SGs are formed at the trans-Golgi network and must undergo a maturation process to become responsive to secretagogues. The production of mature SGs...

Raman spectral signatures of human liver perfusates correlate with oxidation reduction potential.

Molecular medicine reports

Bar-Or R, Rael LT, Curtis CG, Mains CW, Slone DS, Bar-Or D.
PMID: 21475809
Mol Med Rep. 2009 Mar-Apr;2(2):175-80. doi: 10.3892/mmr_00000080.

Biomarkers for the early detection of liver toxicity are crucial in drug development for assessing the safety of a new drug. Oxidation reduction potential (ORP) is an overall measure of the oxidative stress to which a biological component is...

Showing 1 to 12 of 135 entries