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Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment.

Cell communication and signaling : CCS

Wiechert L, Németh J, Pusterla T, Bauer C, De Ponti A, Manthey S, Marhenke S, Vogel A, Klingmüller U, Hess J, Angel P.
PMID: 23241281
Cell Commun Signal. 2012 Dec 15;10(1):40. doi: 10.1186/1478-811X-10-40.

BACKGROUND: Calprotectin consists of the Ca2+-binding proteins S100a8 and S100a9 that are induced in epithelial cells in response to tissue damage and infection. Both proteins are also secreted by activated innate immune cells and numerous studies demonstrate their crucial...

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Wiechert L, Németh J, Pusterla T, et al. Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment. Cell Commun Signal. 2012;10(1):40doi: 10.1186/1478-811X-10-40.
Wiechert, L., Németh, J., Pusterla, T., Bauer, C., De Ponti, A., Manthey, S., Marhenke, S., Vogel, A., Klingmüller, U., Hess, J., & Angel, P. (2012). Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment. Cell communication and signaling : CCS, 10(1), 40. https://doi.org/10.1186/1478-811X-10-40
Wiechert, Lars, et al. "Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment." Cell communication and signaling : CCS vol. 10,1 (2012): 40. doi: https://doi.org/10.1186/1478-811X-10-40
Wiechert L, Németh J, Pusterla T, Bauer C, De Ponti A, Manthey S, Marhenke S, Vogel A, Klingmüller U, Hess J, Angel P. Hepatocyte-specific S100a8 and S100a9 transgene expression in mice causes Cxcl1 induction and systemic neutrophil enrichment. Cell Commun Signal. 2012 Dec 15;10(1):40. doi: 10.1186/1478-811X-10-40. PMID: 23241281; PMCID: PMC3533587.
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Seasonal patterns of total and energy reserve lipids of dominant zooplanktonic crustaceans from a hyper-eutrophic lake.

Oecologia

Arts MT, Evans MS, Robarts RD.
PMID: 28313577
Oecologia. 1992 Jul;90(4):560-571. doi: 10.1007/BF01875451.

Seasonal patterns of lipid reserves and lipid classes of dominant zooplankton in a hyper-eutrophic lake were examined in relation to algal food resources. Triacylglycerol was the principle lipid energy reserve in all five species examined. During the height of...

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Arts MT, Evans MS, Robarts RD. Seasonal patterns of total and energy reserve lipids of dominant zooplanktonic crustaceans from a hyper-eutrophic lake. Oecologia. 1992;90(4):560-571doi: 10.1007/BF01875451.
Arts, M. T., Evans, M. S., & Robarts, R. D. (1992). Seasonal patterns of total and energy reserve lipids of dominant zooplanktonic crustaceans from a hyper-eutrophic lake. Oecologia, 90(4), 560-571. https://doi.org/10.1007/BF01875451
Arts, Michael T, et al. "Seasonal patterns of total and energy reserve lipids of dominant zooplanktonic crustaceans from a hyper-eutrophic lake." Oecologia vol. 90,4 (1992): 560-571. doi: https://doi.org/10.1007/BF01875451
Arts MT, Evans MS, Robarts RD. Seasonal patterns of total and energy reserve lipids of dominant zooplanktonic crustaceans from a hyper-eutrophic lake. Oecologia. 1992 Jul;90(4):560-571. doi: 10.1007/BF01875451. PMID: 28313577.
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Thyroid hormone and seasonal rhythmicity.

Frontiers in endocrinology

Dardente H, Hazlerigg DG, Ebling FJ.
PMID: 24616714
Front Endocrinol (Lausanne). 2014 Feb 26;5:19. doi: 10.3389/fendo.2014.00019. eCollection 2014.

Living organisms show seasonality in a wide array of functions such as reproduction, fattening, hibernation, and migration. At temperate latitudes, changes in photoperiod maintain the alignment of annual rhythms with predictable changes in the environment. The appropriate physiological response...

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Dardente H, Hazlerigg DG, Ebling FJ. Thyroid hormone and seasonal rhythmicity. Front Endocrinol (Lausanne). 2014;5:19doi: 10.3389/fendo.2014.00019.
Dardente, H., Hazlerigg, D. G., & Ebling, F. J. (2014). Thyroid hormone and seasonal rhythmicity. Frontiers in endocrinology, 519. https://doi.org/10.3389/fendo.2014.00019
Dardente, Hugues, et al. "Thyroid hormone and seasonal rhythmicity." Frontiers in endocrinology vol. 5 (2014): 19. doi: https://doi.org/10.3389/fendo.2014.00019
Dardente H, Hazlerigg DG, Ebling FJ. Thyroid hormone and seasonal rhythmicity. Front Endocrinol (Lausanne). 2014 Feb 26;5:19. doi: 10.3389/fendo.2014.00019. eCollection 2014. PMID: 24616714; PMCID: PMC3935485.
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Towards a durability test for washing-machines.

Resources, conservation, and recycling

Stamminger R, Tecchio P, Ardente F, Mathieux F, Niestrath P.
PMID: 29615829
Resour Conserv Recycl. 2018 Apr;131:206-215. doi: 10.1016/j.resconrec.2017.11.014.

Durability plays a key role in enhancing resource conservation and contributing to waste minimization. The washing-machine product group represents a relevant case study for the development of a durability test and as a potential trigger to systematically address durability...

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Stamminger R, Tecchio P, Ardente F, et al. Towards a durability test for washing-machines. Resour Conserv Recycl. 2018;131:206-215doi: 10.1016/j.resconrec.2017.11.014.
Stamminger, R., Tecchio, P., Ardente, F., Mathieux, F., & Niestrath, P. (2018). Towards a durability test for washing-machines. Resources, conservation, and recycling, 131206-215. https://doi.org/10.1016/j.resconrec.2017.11.014
Stamminger, Rainer, et al. "Towards a durability test for washing-machines." Resources, conservation, and recycling vol. 131 (2018): 206-215. doi: https://doi.org/10.1016/j.resconrec.2017.11.014
Stamminger R, Tecchio P, Ardente F, Mathieux F, Niestrath P. Towards a durability test for washing-machines. Resour Conserv Recycl. 2018 Apr;131:206-215. doi: 10.1016/j.resconrec.2017.11.014. PMID: 29615829; PMCID: PMC5824671.
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Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer .

Hepatology communications

Saborowski A, Wolff K, Spielberg S, Beer B, Hartleben B, Erlangga Z, Becker D, Dow LE, Marhenke S, Woller N, Unger K, Schirmacher P, Manns MP, Marquardt JU, Vogel A, Saborowski M.
PMID: 30859153
Hepatol Commun. 2019 Feb 05;3(3):423-436. doi: 10.1002/hep4.1312. eCollection 2019 Mar.

The rising incidence of cholangiocarcinoma (CCA) coupled with a low 5-year survival rate that remains below 10% delineates the urgent need for more effective treatment strategies. Although several recent studies provided detailed information on the genetic landscape of this...

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Saborowski A, Wolff K, Spielberg S, et al. Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer . Hepatol Commun. 2019;3(3):423-436doi: 10.1002/hep4.1312.
Saborowski, A., Wolff, K., Spielberg, S., Beer, B., Hartleben, B., Erlangga, Z., Becker, D., Dow, L. E., Marhenke, S., Woller, N., Unger, K., Schirmacher, P., Manns, M. P., Marquardt, J. U., Vogel, A., & Saborowski, M. (2019). Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer . Hepatology communications, 3(3), 423-436. https://doi.org/10.1002/hep4.1312
Saborowski, Anna, et al. "Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer ." Hepatology communications vol. 3,3 (2019): 423-436. doi: https://doi.org/10.1002/hep4.1312
Saborowski A, Wolff K, Spielberg S, Beer B, Hartleben B, Erlangga Z, Becker D, Dow LE, Marhenke S, Woller N, Unger K, Schirmacher P, Manns MP, Marquardt JU, Vogel A, Saborowski M. Murine Liver Organoids as a Genetically Flexible System to Study Liver Cancer . Hepatol Commun. 2019 Feb 05;3(3):423-436. doi: 10.1002/hep4.1312. eCollection 2019 Mar. PMID: 30859153; PMCID: PMC6396372.
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Correction to: Landraces of snake melon, an ancient Middle Eastern crop, reveal extensive morphological and DNA diversity for potential genetic improvement.

BMC genetics

Omari S, Kamenir Y, Benichou JIC, Pariente S, Sela H, Perl-Treves R.
PMID: 30001200
BMC Genet. 2018 Jul 12;19(1):44. doi: 10.1186/s12863-018-0632-9.

Following publication of the original article [1], the authors reported the need for a more detailed acknowledgement of the source of the samples that were analyzed and their coordinates, which are discussed in the 'Methods' section of the article....

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Omari S, Kamenir Y, Benichou JIC, et al. Correction to: Landraces of snake melon, an ancient Middle Eastern crop, reveal extensive morphological and DNA diversity for potential genetic improvement. BMC Genet. 2018;19(1):44doi: 10.1186/s12863-018-0632-9.
Omari, S., Kamenir, Y., Benichou, J. I. C., Pariente, S., Sela, H., & Perl-Treves, R. (2018). Correction to: Landraces of snake melon, an ancient Middle Eastern crop, reveal extensive morphological and DNA diversity for potential genetic improvement. BMC genetics, 19(1), 44. https://doi.org/10.1186/s12863-018-0632-9
Omari, Samer, et al. "Correction to: Landraces of snake melon, an ancient Middle Eastern crop, reveal extensive morphological and DNA diversity for potential genetic improvement." BMC genetics vol. 19,1 (2018): 44. doi: https://doi.org/10.1186/s12863-018-0632-9
Omari S, Kamenir Y, Benichou JIC, Pariente S, Sela H, Perl-Treves R. Correction to: Landraces of snake melon, an ancient Middle Eastern crop, reveal extensive morphological and DNA diversity for potential genetic improvement. BMC Genet. 2018 Jul 12;19(1):44. doi: 10.1186/s12863-018-0632-9. PMID: 30001200; PMCID: PMC6042412.
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Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial.

JACC. Basic to translational science

Leucker TM, Osburn WO, Reventun P, Smith K, Claggett B, Kirwan BA, de Brouwer S, Williams MS, Gerstenblith G, Hager DN, Streiff MB, Solomon SD, Lowenstein CJ.
PMID: 34904132
JACC Basic Transl Sci. 2021 Dec 08; doi: 10.1016/j.jacbts.2021.09.013. Epub 2021 Dec 08.

COVID-19 is characterized by vascular inflammation and thrombosis, including elevations in P-selectin, a mediator of inflammation released by endothelial cells. We tested the effect of P-selectin inhibition on biomarkers of thrombosis and inflammation in patients with COVID-19. Hospitalized patients...

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Leucker TM, Osburn WO, Reventun P, et al. Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial. JACC Basic Transl Sci. 2021;doi: 10.1016/j.jacbts.2021.09.013.
Leucker, T. M., Osburn, W. O., Reventun, P., Smith, K., Claggett, B., Kirwan, B. A., de Brouwer, S., Williams, M. S., Gerstenblith, G., Hager, D. N., Streiff, M. B., Solomon, S. D., & Lowenstein, C. J. (2021). Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial. JACC. Basic to translational science, . https://doi.org/10.1016/j.jacbts.2021.09.013
Leucker, Thorsten M, et al. "Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial." JACC. Basic to translational science vol. (2021). doi: https://doi.org/10.1016/j.jacbts.2021.09.013
Leucker TM, Osburn WO, Reventun P, Smith K, Claggett B, Kirwan BA, de Brouwer S, Williams MS, Gerstenblith G, Hager DN, Streiff MB, Solomon SD, Lowenstein CJ. Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial. JACC Basic Transl Sci. 2021 Dec 08; doi: 10.1016/j.jacbts.2021.09.013. Epub 2021 Dec 08. PMID: 34904132; PMCID: PMC8653991.
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Analysis of Failed Two-Stage Procedures with Resection Arthroplasty as the First Stage in Periprosthetic Hip Joint Infections.

Journal of clinical medicine

Simon S, Frank BJH, Gardete S, Aichmair A, Mitterer JA, Dominkus M, Hofstaetter JG.
PMID: 34768700
J Clin Med. 2021 Nov 05;10(21). doi: 10.3390/jcm10215180.

Resection arthroplasty can be performed as the first stage of a two-stage procedure in some patients with severe periprosthetic hip joint infections with poor bone stock. This retrospective study aimed to evaluate factors associated with the subsequent failure or...

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Simon S, Frank BJH, Gardete S, et al. Analysis of Failed Two-Stage Procedures with Resection Arthroplasty as the First Stage in Periprosthetic Hip Joint Infections. J Clin Med. 2021;10(21)doi: 10.3390/jcm10215180.
Simon, S., Frank, B. J. H., Gardete, S., Aichmair, A., Mitterer, J. A., Dominkus, M., & Hofstaetter, J. G. (2021). Analysis of Failed Two-Stage Procedures with Resection Arthroplasty as the First Stage in Periprosthetic Hip Joint Infections. Journal of clinical medicine, 10(21), . https://doi.org/10.3390/jcm10215180
Simon, Sebastian, et al. "Analysis of Failed Two-Stage Procedures with Resection Arthroplasty as the First Stage in Periprosthetic Hip Joint Infections." Journal of clinical medicine vol. 10,21 (2021). doi: https://doi.org/10.3390/jcm10215180
Simon S, Frank BJH, Gardete S, Aichmair A, Mitterer JA, Dominkus M, Hofstaetter JG. Analysis of Failed Two-Stage Procedures with Resection Arthroplasty as the First Stage in Periprosthetic Hip Joint Infections. J Clin Med. 2021 Nov 05;10(21). doi: 10.3390/jcm10215180. PMID: 34768700; PMCID: PMC8584448.
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Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations.

The Lancet. Respiratory medicine

Aliberti S, Goeminne PC, O'Donnell AE, Aksamit TR, Al-Jahdali H, Barker AF, Blasi F, Boersma WG, Crichton ML, De Soyza A, Dimakou KE, Elborn SJ, Feldman C, Tiddens H, Haworth CS, Hill AT, Loebinger MR, Martinez-Garcia MA, Meerburg JJ, Menendez R, Morgan LC, Murris MS, Polverino E, Ringshausen FC, Shteinberg M, Sverzellati N, Tino G, Torres A, Vandendriessche T, Vendrell M, Welte T, Wilson R, Wong CA, Chalmers JD.
PMID: 34570994
Lancet Respir Med. 2021 Sep 24; doi: 10.1016/S2213-2600(21)00277-0. Epub 2021 Sep 24.

Bronchiectasis refers to both a clinical disease and a radiological appearance that has multiple causes and can be associated with a range of conditions. Disease heterogeneity and the absence of standardised definitions have hampered clinical trials of treatments for...

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Aliberti S, Goeminne PC, O'Donnell AE, et al. Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations. Lancet Respir Med. 2021;doi: 10.1016/S2213-2600(21)00277-0.
Aliberti, S., Goeminne, P. C., O'Donnell, A. E., Aksamit, T. R., Al-Jahdali, H., Barker, A. F., Blasi, F., Boersma, W. G., Crichton, M. L., De Soyza, A., Dimakou, K. E., Elborn, S. J., Feldman, C., Tiddens, H., Haworth, C. S., Hill, A. T., Loebinger, M. R., Martinez-Garcia, M. A., Meerburg, J. J., Menendez, R., Morgan, L. C., Murris, M. S., Polverino, E., Ringshausen, F. C., Shteinberg, M., Sverzellati, N., Tino, G., Torres, A., Vandendriessche, T., Vendrell, M., Welte, T., Wilson, R., Wong, C. A., & Chalmers, J. D. (2021). Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations. The Lancet. Respiratory medicine, . https://doi.org/10.1016/S2213-2600(21)00277-0
Aliberti, Stefano, et al. "Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations." The Lancet. Respiratory medicine vol. (2021). doi: https://doi.org/10.1016/S2213-2600(21)00277-0
Aliberti S, Goeminne PC, O'Donnell AE, Aksamit TR, Al-Jahdali H, Barker AF, Blasi F, Boersma WG, Crichton ML, De Soyza A, Dimakou KE, Elborn SJ, Feldman C, Tiddens H, Haworth CS, Hill AT, Loebinger MR, Martinez-Garcia MA, Meerburg JJ, Menendez R, Morgan LC, Murris MS, Polverino E, Ringshausen FC, Shteinberg M, Sverzellati N, Tino G, Torres A, Vandendriessche T, Vendrell M, Welte T, Wilson R, Wong CA, Chalmers JD. Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations. Lancet Respir Med. 2021 Sep 24; doi: 10.1016/S2213-2600(21)00277-0. Epub 2021 Sep 24. PMID: 34570994.
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Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?.

International journal of endocrinology

Giagulli VA, Silvestrini A, Bruno C, Triggiani V, Mordente A, Mancini A.
PMID: 32411230
Int J Endocrinol. 2020 Jan 21;2020:9649838. doi: 10.1155/2020/9649838. eCollection 2020.

Hypogonadotropic hypogonadism (HH) can be sustained by organic or functional alterations of the hypothalamic-pituitary-testicular axis. Functional HH is related to systemic alterations, such as obesity or chronic inflammatory diseases, but could contribute to a negative course of the illness....

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Giagulli VA, Silvestrini A, Bruno C, et al. Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?. Int J Endocrinol. 2020;2020:9649838doi: 10.1155/2020/9649838.
Giagulli, V. A., Silvestrini, A., Bruno, C., Triggiani, V., Mordente, A., & Mancini, A. (2020). Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?. International journal of endocrinology, 20209649838. https://doi.org/10.1155/2020/9649838
Giagulli, Vito A, et al. "Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?." International journal of endocrinology vol. 2020 (2020): 9649838. doi: https://doi.org/10.1155/2020/9649838
Giagulli VA, Silvestrini A, Bruno C, Triggiani V, Mordente A, Mancini A. Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?. Int J Endocrinol. 2020 Jan 21;2020:9649838. doi: 10.1155/2020/9649838. eCollection 2020. PMID: 32411230; PMCID: PMC7201459.
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Low Molecular Weight Dextran Sulfate (ILB.

Antioxidants (Basel, Switzerland)

Lazzarino G, Amorini AM, Barnes NM, Bruce L, Mordente A, Lazzarino G, Pietro VD, Tavazzi B, Belli A, Logan A.
PMID: 32927770
Antioxidants (Basel). 2020 Sep 10;9(9). doi: 10.3390/antiox9090850.

Traumatic brain injury (TBI) is the leading cause of death and disability in people less than 40 years of age in Western countries. Currently, there are no satisfying pharmacological treatments for TBI patients. In this study, we subjected rats...

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Lazzarino G, Amorini AM, Barnes NM, et al. Low Molecular Weight Dextran Sulfate (ILB. Antioxidants (Basel). 2020;9(9)doi: 10.3390/antiox9090850.
Lazzarino, G., Amorini, A. M., Barnes, N. M., Bruce, L., Mordente, A., Lazzarino, G., Pietro, V. D., Tavazzi, B., Belli, A., & Logan, A. (2020). Low Molecular Weight Dextran Sulfate (ILB. Antioxidants (Basel, Switzerland), 9(9), . https://doi.org/10.3390/antiox9090850
Lazzarino, Giacomo, et al. "Low Molecular Weight Dextran Sulfate (ILB." Antioxidants (Basel, Switzerland) vol. 9,9 (2020). doi: https://doi.org/10.3390/antiox9090850
Lazzarino G, Amorini AM, Barnes NM, Bruce L, Mordente A, Lazzarino G, Pietro VD, Tavazzi B, Belli A, Logan A. Low Molecular Weight Dextran Sulfate (ILB. Antioxidants (Basel). 2020 Sep 10;9(9). doi: 10.3390/antiox9090850. PMID: 32927770; PMCID: PMC7555574.
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Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial.

JACC. Basic to translational science

Leucker TM, Osburn WO, Reventun P, Smith K, Claggett B, Kirwan BA, de Brouwer S, Williams MS, Gerstenblith G, Hager DN, Streiff MB, Solomon SD, Lowenstein CJ.
PMID: 34904132
JACC Basic Transl Sci. 2021 Dec;6(12):935-945. doi: 10.1016/j.jacbts.2021.09.013. Epub 2021 Dec 08.

COVID-19 is characterized by vascular inflammation and thrombosis, including elevations in P-selectin, a mediator of inflammation released by endothelial cells. We tested the effect of P-selectin inhibition on biomarkers of thrombosis and inflammation in patients with COVID-19. Hospitalized patients...

Cite
Leucker TM, Osburn WO, Reventun P, et al. Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial. JACC Basic Transl Sci. 2021;6(12):935-945doi: 10.1016/j.jacbts.2021.09.013.
Leucker, T. M., Osburn, W. O., Reventun, P., Smith, K., Claggett, B., Kirwan, B. A., de Brouwer, S., Williams, M. S., Gerstenblith, G., Hager, D. N., Streiff, M. B., Solomon, S. D., & Lowenstein, C. J. (2021). Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial. JACC. Basic to translational science, 6(12), 935-945. https://doi.org/10.1016/j.jacbts.2021.09.013
Leucker, Thorsten M, et al. "Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial." JACC. Basic to translational science vol. 6,12 (2021): 935-945. doi: https://doi.org/10.1016/j.jacbts.2021.09.013
Leucker TM, Osburn WO, Reventun P, Smith K, Claggett B, Kirwan BA, de Brouwer S, Williams MS, Gerstenblith G, Hager DN, Streiff MB, Solomon SD, Lowenstein CJ. Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-19: A Placebo-Controlled, Randomized Trial. JACC Basic Transl Sci. 2021 Dec;6(12):935-945. doi: 10.1016/j.jacbts.2021.09.013. Epub 2021 Dec 08. PMID: 34904132; PMCID: PMC8653991.
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