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Showing 1 to 12 of 79 entries
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Socioeconomic consequences of non-insulin-dependent diabetes mellitus.

Diabetes/metabolism reviews

Lebrun T, Marissal JP.
PMID: 8529490
Diabetes Metab Rev. 1995 Sep;11:S87-95. doi: 10.1002/dmr.5610110513.

No abstract available.

Onset of Pup Locomotion Coincides with Loss of NR2C/D-Mediated Cortico-Striatal EPSCs and Dampening of Striatal Network Immature Activity.

Frontiers in cellular neuroscience

Dehorter N, Michel FJ, Marissal T, Rotrou Y, Matrot B, Lopez C, Humphries MD, Hammond C.
PMID: 22125512
Front Cell Neurosci. 2011 Nov 21;5:24. doi: 10.3389/fncel.2011.00024. eCollection 2011.

Adult motor coordination requires strong coincident cortical excitatory input to hyperpolarized medium spiny neurons (MSNs), the dominant neuronal population of the striatum. However, cortical and subcortical neurons generate during development large ongoing patterns required for activity-dependent construction of networks....

Protein Composition Reflects Extracellular Vesicle Heterogeneity.

Proteomics

Vagner T, Chin A, Mariscal J, Bannykh S, Engman DM, Di Vizio D.
PMID: 30793499
Proteomics. 2019 Apr;19(8):e1800167. doi: 10.1002/pmic.201800167. Epub 2019 Apr 02.

Extracellular vesicles (EVs) are membrane-enclosed particles that are released by virtually all cells from all living organisms. EVs shuttle biologically active cargo including protein, RNA, and DNA between cells. When shed by cancer cells, they function as potent intercellular...

The old becomes new: advances in imaging techniques to assess nephron mass in children.

Pediatric nephrology (Berlin, Germany)

DeFreitas MJ, Katsoufis CP, Infante JC, Granda ML, Abitbol CL, Fornoni A.
PMID: 31953750
Pediatr Nephrol. 2021 Mar;36(3):517-525. doi: 10.1007/s00467-020-04477-8. Epub 2020 Jan 17.

Renal imaging is widely used in the assessment of surrogate markers of nephron mass correlated to renal function. Autopsy studies have tested the validity of various imaging modalities in accurately estimating "true" nephron mass. However, in vivo assessment of...

Monkey Bar Dimensions Associated with Pediatric Upper Extremity Fractures Show Deviations from United States Product Safety Commission Recommendations.

Cureus

Teitelbaum MP, Stankovits L, Curatolo E.
PMID: 32038892
Cureus. 2020 Jan 01;12(1):e6534. doi: 10.7759/cureus.6534.

Background Monkey bar injuries account for the majority of playground injuries, and 34% result in a fracture. Studies have shown that there has been no decline in the number of monkey bar injuries over several decades. Our goal was...

The Multifaceted Roles of the Tumor Susceptibility Gene 101 (TSG101) in Normal Development and Disease.

Cancers

Ferraiuolo RM, Manthey KC, Stanton MJ, Triplett AA, Wagner KU.
PMID: 32075127
Cancers (Basel). 2020 Feb 14;12(2). doi: 10.3390/cancers12020450.

The multidomain protein encoded by the

Whole Genome Sequencing Surveillance and Machine Learning of the Electronic Health Record for Enhanced Healthcare Outbreak Detection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Sundermann AJ, Chen J, Kumar P, Ayres AM, Cho ST, Ezeonwuka C, Griffith MP, Miller JK, Mustapha MM, Pasculle AW, Saul MI, Shutt KA, Srinivasa V, Waggle K, Snyder DJ, Cooper VS, Van Tyne D, Snyder GM, Marsh JW, Dubrawski A, Roberts MS, Harrison LH.
PMID: 34791136
Clin Infect Dis. 2021 Nov 17; doi: 10.1093/cid/ciab946. Epub 2021 Nov 17.

BACKGROUND: Most hospitals use traditional infection prevention (IP) methods for outbreak detection. We developed the Enhanced Detection System for Healthcare-Associated Transmission (EDS-HAT), which combines whole genome sequencing (WGS) surveillance and machine learning (ML) of the electronic health record (EHR)...

Perceptions of Diabetes Technology Use in Cystic Fibrosis-Related Diabetes Management.

Diabetes technology & therapeutics

Marks BE, Kilberg MJ, Aliaj E, Fredkin K, Hudson J, Riva D, Román C, Kelly A, Putman MS.
PMID: 34185606
Diabetes Technol Ther. 2021 Nov;23(11):753-759. doi: 10.1089/dia.2021.0201. Epub 2021 Jul 20.

No abstract available.

Clinical importance of high-mannose, fucosylated, and complex N-glycans in breast cancer metastasis.

JCI insight

Ščupáková K, Adelaja OT, Balluff B, Ayyappan V, Tressler CM, Jenkinson NM, Claes BS, Bowman AP, Cimino-Mathews AM, White MJ, Argani P, Heeren RM, Glunde K.
PMID: 34752419
JCI Insight. 2021 Dec 22;6(24). doi: 10.1172/jci.insight.146945.

BACKGROUND: Although aberrant glycosylation is recognized as a hallmark of cancer, glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While preclinical studies show that the glycocalyx coating of cancer cells is involved in adhesion, migration,...

Dentate Granule Cells Recruited in the Home Environment Display Distinctive Properties.

Frontiers in cellular neuroscience

Pléau C, Peret A, Pearlstein E, Scalfati T, Vigier A, Marti G, Michel FJ, Marissal T, Crépel V.
PMID: 33519383
Front Cell Neurosci. 2021 Jan 15;14:609123. doi: 10.3389/fncel.2020.609123. eCollection 2020.

The dentate granule cells (DGCs) play a crucial role in learning and memory. Many studies have described the role and physiological properties of these sparsely active neurons using different behavioral contexts. However, the morpho-functional features of DGCs recruited in...

Improved healing of chronic diabetic foot wounds in a prospective randomised controlled multi-centre clinical trial with a microvascular tissue allograft.

International wound journal

Gould LJ, Orgill DP, Armstrong DG, Galiano RD, Glat PM, Zelen CM, DiDomenico LA, Carter MJ, Li WW.
PMID: 34469077
Int Wound J. 2021 Sep 01; doi: 10.1111/iwj.13679. Epub 2021 Sep 01.

This study assesses the impact of a processed microvascular tissue (PMVT) allograft on wound closure and healing in a prospective, single-blinded, multi-centre, randomised controlled clinical trial of 100 subjects with Wagner Grade 1 and 2 chronic neuropathic diabetic foot...

A prospective clinical trial evaluating changes in the wound microenvironment in patients with chronic venous leg ulcers treated with a hypothermically stored amniotic membrane.

International wound journal

McQuilling JP, Carter MJ, Fulton JA, Patel K, Doner B, Serena TE, Mowry KC.
PMID: 33955178
Int Wound J. 2022 Jan;19(1):144-155. doi: 10.1111/iwj.13606. Epub 2021 May 06.

Amniotic tissues have been long utilised to treat chronic wounds; however, there are few studies evaluating how the wound microenvironment responds to these therapies. The goal of this study was to evaluate the changes in wounds treated with a...

Showing 1 to 12 of 79 entries