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RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling

STEM and diversification

Jeancolas C, Matsubara YJ, Vybornyi M.
GSID: Ply-sJ_iKTwJ
C Jeancolas, YJ Matsubara, M Vybornyi… - Chemical …, 2021 - pubs.rsc.org

… 1 RNA substrates are composed of a “stem” (blue) and a tag (red). RNA1 stem differs from RNA2 and RNA3 stems by two nucleotides (bold). RNA2 and RNA3 have a self-…

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JEANCOLAS, Cyrille, et al. RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling. Chemical Communications, 2021, vol. 57, no 61, p. 7517-7520.
Jeancolas, C., Matsubara, Y. J., Vybornyi, M., Lambert, C. N., Blokhuis, A., Alline, T., ... & Nghe, P. (2021). RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling. Chemical Communications, 57(61), 7517-7520.
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[Structure and function of the family unit and the modern problems--a sociologic aspect].

Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica

Matsubara H.
PMID: 4859104
Seishin Shinkeigaku Zasshi. 1974;76(3):163-7.

No abstract available.

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Matsubara H. [Structure and function of the family unit and the modern problems--a sociologic aspect]. Seishin Shinkeigaku Zasshi. 1974;76(3):163-7
Matsubara, H. (1974). [Structure and function of the family unit and the modern problems--a sociologic aspect]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 76(3), 163-7.
Matsubara, H. "[Structure and function of the family unit and the modern problems--a sociologic aspect]." Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica vol. 76,3 (1974): 163-7.
Matsubara H. [Structure and function of the family unit and the modern problems--a sociologic aspect]. Seishin Shinkeigaku Zasshi. 1974;76(3):163-7. Japanese. PMID: 4859104.
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[Leiomyoma of the scrotum: suggestive of malignancy].

Gan no rinsho. Japan journal of cancer clinics

Matsubara J, Miura K, Morita K.
PMID: 5101460
Gan No Rinsho. 1971;17(2):151-4.

No abstract available.

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Matsubara J, Miura K, Morita K. [Leiomyoma of the scrotum: suggestive of malignancy]. Gan No Rinsho. 1971;17(2):151-4
Matsubara, J., Miura, K., & Morita, K. (1971). [Leiomyoma of the scrotum: suggestive of malignancy]. Gan no rinsho. Japan journal of cancer clinics, 17(2), 151-4.
Matsubara, J, et al. "[Leiomyoma of the scrotum: suggestive of malignancy]." Gan no rinsho. Japan journal of cancer clinics vol. 17,2 (1971): 151-4.
Matsubara J, Miura K, Morita K. [Leiomyoma of the scrotum: suggestive of malignancy]. Gan No Rinsho. 1971;17(2):151-4. Japanese. PMID: 5101460.
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Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse.

Molecular neurodegeneration

Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Urisu T, Yamamoto N, Shoji M, Yanagisawa K, Michikawa M, Matsubara E.
PMID: 21375782
Mol Neurodegener. 2011 Mar 06;6(1):20. doi: 10.1186/1750-1326-6-20.

BACKGROUND: Several lines of evidence indicate that memory loss represents a synaptic failure caused by soluble amyloid β (Aβ) oligomers. However, the pathological relevance of Aβ oligomers (AβOs) as the trigger of synaptic or neuronal degeneration, and the possible...

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Takamura A, Okamoto Y, Kawarabayashi T, et al. Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse. Mol Neurodegener. 2011;6(1):20doi: 10.1186/1750-1326-6-20.
Takamura, A., Okamoto, Y., Kawarabayashi, T., Yokoseki, T., Shibata, M., Mouri, A., Nabeshima, T., Sun, H., Abe, K., Urisu, T., Yamamoto, N., Shoji, M., Yanagisawa, K., Michikawa, M., & Matsubara, E. (2011). Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse. Molecular neurodegeneration, 6(1), 20. https://doi.org/10.1186/1750-1326-6-20
Takamura, Ayumi, et al. "Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse." Molecular neurodegeneration vol. 6,1 (2011): 20. doi: https://doi.org/10.1186/1750-1326-6-20
Takamura A, Okamoto Y, Kawarabayashi T, Yokoseki T, Shibata M, Mouri A, Nabeshima T, Sun H, Abe K, Urisu T, Yamamoto N, Shoji M, Yanagisawa K, Michikawa M, Matsubara E. Extracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouse. Mol Neurodegener. 2011 Mar 06;6(1):20. doi: 10.1186/1750-1326-6-20. PMID: 21375782; PMCID: PMC3061944.
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Catalytic and Enantioselective Synthesis of Chiral Multisubstituted Tribenzothiepins by Intermolecular Cycloadditions.

Angewandte Chemie (International ed. in English)

Tahara YK, Matsubara R, Mitake A, Sato T, Kanyiva KS, Shibata T.
PMID: 26933763
Angew Chem Int Ed Engl. 2016 Mar 24;55(14):4552-6. doi: 10.1002/anie.201511876. Epub 2016 Mar 02.

The first catalytic and highly enantioselective synthesis of tribenzothiepin derivatives was achieved. Two types of intermolecular cycloadditions using either diphenyl-sulfide-tethered diynes or 2-phenyl sulfanylbenzene-tethered diynes with a monoalkyne successfully gave chiral multisubstituted tribenzothiepins in good to excellent ee values...

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Tahara YK, Matsubara R, Mitake A, et al. Catalytic and Enantioselective Synthesis of Chiral Multisubstituted Tribenzothiepins by Intermolecular Cycloadditions. Angew Chem Int Ed Engl. 2016;55(14):4552-6doi: 10.1002/anie.201511876.
Tahara, Y. K., Matsubara, R., Mitake, A., Sato, T., Kanyiva, K. S., & Shibata, T. (2016). Catalytic and Enantioselective Synthesis of Chiral Multisubstituted Tribenzothiepins by Intermolecular Cycloadditions. Angewandte Chemie (International ed. in English), 55(14), 4552-6. https://doi.org/10.1002/anie.201511876
Tahara, Yu-Ki, et al. "Catalytic and Enantioselective Synthesis of Chiral Multisubstituted Tribenzothiepins by Intermolecular Cycloadditions." Angewandte Chemie (International ed. in English) vol. 55,14 (2016): 4552-6. doi: https://doi.org/10.1002/anie.201511876
Tahara YK, Matsubara R, Mitake A, Sato T, Kanyiva KS, Shibata T. Catalytic and Enantioselective Synthesis of Chiral Multisubstituted Tribenzothiepins by Intermolecular Cycloadditions. Angew Chem Int Ed Engl. 2016 Mar 24;55(14):4552-6. doi: 10.1002/anie.201511876. Epub 2016 Mar 02. PMID: 26933763.
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Membranous nephropathy associated with type 1 autoimmune pancreatitis and dominant glomerular IgG4 deposit.

CEN case reports

Sueta S, Kondo M, Matsubara T, Yasuhara Y, Akiyama S, Imai E, Amaike H, Tagawa M.
PMID: 28509238
CEN Case Rep. 2014 May;3(1):18-23. doi: 10.1007/s13730-013-0077-y. Epub 2013 May 03.

We report a case of membranous nephropathy associated with type 1 autoimmune pancreatitis. A 58-year-old man presented with anorexia. Work-up revealed a mass in the pancreatic head, which was subsequently resected. Pathological examination showed diffuse infiltration of immunoglobulin (Ig)...

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Sueta S, Kondo M, Matsubara T, et al. Membranous nephropathy associated with type 1 autoimmune pancreatitis and dominant glomerular IgG4 deposit. CEN Case Rep. 2013;3(1):18-23doi: 10.1007/s13730-013-0077-y.
Sueta, S., Kondo, M., Matsubara, T., Yasuhara, Y., Akiyama, S., Imai, E., Amaike, H., & Tagawa, M. (2014). Membranous nephropathy associated with type 1 autoimmune pancreatitis and dominant glomerular IgG4 deposit. CEN case reports, 3(1), 18-23. https://doi.org/10.1007/s13730-013-0077-y
Sueta, Shinichi, et al. "Membranous nephropathy associated with type 1 autoimmune pancreatitis and dominant glomerular IgG4 deposit." CEN case reports vol. 3,1 (2014): 18-23. doi: https://doi.org/10.1007/s13730-013-0077-y
Sueta S, Kondo M, Matsubara T, Yasuhara Y, Akiyama S, Imai E, Amaike H, Tagawa M. Membranous nephropathy associated with type 1 autoimmune pancreatitis and dominant glomerular IgG4 deposit. CEN Case Rep. 2014 May;3(1):18-23. doi: 10.1007/s13730-013-0077-y. Epub 2013 May 03. PMID: 28509238; PMCID: PMC5411534.
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Striking Differences in Properties of Geometric Isomers of [Ir(tpy)(ppy)H](+): Experimental and Computational Studies of their Hydricities, Interaction with CO2, and Photochemistry.

Angewandte Chemie (International ed. in English)

Garg K, Matsubara Y, Ertem MZ, Lewandowska-Andralojc A, Sato S, Szalda DJ, Muckerman JT, Fujita E.
PMID: 26427767
Angew Chem Int Ed Engl. 2015 Nov 16;54(47):14128-32. doi: 10.1002/anie.201506961. Epub 2015 Oct 02.

We prepared two geometric isomers of [Ir(tpy)(ppy)H](+), previously proposed as a key intermediate in the photochemical reduction of CO2 to CO, and characterized their notably different ground- and excited-state interactions with CO2 and their hydricities using experimental and computational...

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Garg K, Matsubara Y, Ertem MZ, et al. Striking Differences in Properties of Geometric Isomers of [Ir(tpy)(ppy)H](+): Experimental and Computational Studies of their Hydricities, Interaction with CO2, and Photochemistry. Angew Chem Int Ed Engl. 2015;54(47):14128-32doi: 10.1002/anie.201506961.
Garg, K., Matsubara, Y., Ertem, M. Z., Lewandowska-Andralojc, A., Sato, S., Szalda, D. J., Muckerman, J. T., & Fujita, E. (2015). Striking Differences in Properties of Geometric Isomers of [Ir(tpy)(ppy)H](+): Experimental and Computational Studies of their Hydricities, Interaction with CO2, and Photochemistry. Angewandte Chemie (International ed. in English), 54(47), 14128-32. https://doi.org/10.1002/anie.201506961
Garg, Komal, et al. "Striking Differences in Properties of Geometric Isomers of [Ir(tpy)(ppy)H](+): Experimental and Computational Studies of their Hydricities, Interaction with CO2, and Photochemistry." Angewandte Chemie (International ed. in English) vol. 54,47 (2015): 14128-32. doi: https://doi.org/10.1002/anie.201506961
Garg K, Matsubara Y, Ertem MZ, Lewandowska-Andralojc A, Sato S, Szalda DJ, Muckerman JT, Fujita E. Striking Differences in Properties of Geometric Isomers of [Ir(tpy)(ppy)H](+): Experimental and Computational Studies of their Hydricities, Interaction with CO2, and Photochemistry. Angew Chem Int Ed Engl. 2015 Nov 16;54(47):14128-32. doi: 10.1002/anie.201506961. Epub 2015 Oct 02. PMID: 26427767.
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SU-E-J-31: Direct Point Dose Verification Using IGRT for Actual Beam Delivery.

Medical physics

Matsubara K, Kohno R, Nishioka S, Shibuya T, Ariji T, Akimoto T, Saitoh H.
PMID: 28517591
Med Phys. 2012 Jun;39(6):3659. doi: 10.1118/1.4734864.

PURPOSE: In radiation therapy, treatment planning for patients is performed using pre-acquired CT images. However, many patients with head-and-neck (H&N) cancer have tumor shrinkage and/or weight loss during their treatment course. Daily positional error of patients also causes unexpected...

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Matsubara K, Kohno R, Nishioka S, et al. SU-E-J-31: Direct Point Dose Verification Using IGRT for Actual Beam Delivery. Med Phys. 2012;39(6):3659doi: 10.1118/1.4734864.
Matsubara, K., Kohno, R., Nishioka, S., Shibuya, T., Ariji, T., Akimoto, T., & Saitoh, H. (2012). SU-E-J-31: Direct Point Dose Verification Using IGRT for Actual Beam Delivery. Medical physics, 39(6), 3659. https://doi.org/10.1118/1.4734864
Matsubara, K, et al. "SU-E-J-31: Direct Point Dose Verification Using IGRT for Actual Beam Delivery." Medical physics vol. 39,6 (2012): 3659. doi: https://doi.org/10.1118/1.4734864
Matsubara K, Kohno R, Nishioka S, Shibuya T, Ariji T, Akimoto T, Saitoh H. SU-E-J-31: Direct Point Dose Verification Using IGRT for Actual Beam Delivery. Med Phys. 2012 Jun;39(6):3659. doi: 10.1118/1.4734864. PMID: 28517591.
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Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report.

Surgical case reports

Otsuka R, Kano M, Hayashi H, Hanari N, Gunji H, Hayano K, Matsubara H.
PMID: 27059471
Surg Case Rep. 2016 Dec;2(1):33. doi: 10.1186/s40792-016-0161-6. Epub 2016 Apr 08.

A 44-year-old man consulted an internist because of abnormalities in an upper gastrointestinal series. It showed an elevated lesion with central depression in the greater curvature of the middle part of the stomach. Upper gastrointestinal endoscopy showed an elevated...

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Otsuka R, Kano M, Hayashi H, et al. Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report. Surg Case Rep. 2016;2(1):33doi: 10.1186/s40792-016-0161-6.
Otsuka, R., Kano, M., Hayashi, H., Hanari, N., Gunji, H., Hayano, K., & Matsubara, H. (2016). Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report. Surgical case reports, 2(1), 33. https://doi.org/10.1186/s40792-016-0161-6
Otsuka, Ryota, et al. "Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report." Surgical case reports vol. 2,1 (2016): 33. doi: https://doi.org/10.1186/s40792-016-0161-6
Otsuka R, Kano M, Hayashi H, Hanari N, Gunji H, Hayano K, Matsubara H. Probable IgG4-related sclerosing disease presenting as a gastric submucosal tumor with an intense tracer uptake on PET/CT: a case report. Surg Case Rep. 2016 Dec;2(1):33. doi: 10.1186/s40792-016-0161-6. Epub 2016 Apr 08. PMID: 27059471; PMCID: PMC4826359.
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Chronic encapsulated intracerebral hematoma: Three case reports and a literature review.

Surgical neurology international

Nishiyama A, Toi H, Takai H, Hirai S, Yokosuka K, Matsushita N, Hirano K, Matsubara S, Nishimura H, Uno M.
PMID: 25024888
Surg Neurol Int. 2014 Jun 06;5:88. doi: 10.4103/2152-7806.134076. eCollection 2014.

BACKGROUND: Chronic encapsulated intracerebral hematoma (CEIH) is one type of intracerebral hematoma that sometimes grows progressively while forming a capsule and presenting with neurological deficits. Although many cases of CEIH have been reported, correct preoperative diagnosis is very difficult....

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Nishiyama A, Toi H, Takai H, et al. Chronic encapsulated intracerebral hematoma: Three case reports and a literature review. Surg Neurol Int. 2014;5:88doi: 10.4103/2152-7806.134076.
Nishiyama, A., Toi, H., Takai, H., Hirai, S., Yokosuka, K., Matsushita, N., Hirano, K., Matsubara, S., Nishimura, H., & Uno, M. (2014). Chronic encapsulated intracerebral hematoma: Three case reports and a literature review. Surgical neurology international, 588. https://doi.org/10.4103/2152-7806.134076
Nishiyama, Akira, et al. "Chronic encapsulated intracerebral hematoma: Three case reports and a literature review." Surgical neurology international vol. 5 (2014): 88. doi: https://doi.org/10.4103/2152-7806.134076
Nishiyama A, Toi H, Takai H, Hirai S, Yokosuka K, Matsushita N, Hirano K, Matsubara S, Nishimura H, Uno M. Chronic encapsulated intracerebral hematoma: Three case reports and a literature review. Surg Neurol Int. 2014 Jun 06;5:88. doi: 10.4103/2152-7806.134076. eCollection 2014. PMID: 25024888; PMCID: PMC4093747.
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A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography.

Journal of medical ultrasonics (2001)

Ishikawa T, Itoh A, Kawashima H, Ohno E, Matsubara H, Nakamura M, Miyahara R, Ohmiya N, Goto H, Hirooka Y.
PMID: 27278586
J Med Ultrason (2001). 2011 Oct;38(4):209. doi: 10.1007/s10396-011-0313-z. Epub 2011 Jun 17.

We used contrast-enhanced endoscopic ultrasonography (CE-EUS) to diagnose a case of solid-pseudopapillary neoplasm (SPN) in an adult man. A 58-year-old man was referred to our hospital because of a pancreatic mass found by positron emission tomography (PET) using (18)F-fluorodeoxyglucose...

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Ishikawa T, Itoh A, Kawashima H, et al. A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography. J Med Ultrason (2001). 2011;38(4):209doi: 10.1007/s10396-011-0313-z.
Ishikawa, T., Itoh, A., Kawashima, H., Ohno, E., Matsubara, H., Nakamura, M., Miyahara, R., Ohmiya, N., Goto, H., & Hirooka, Y. (2011). A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography. Journal of medical ultrasonics (2001), 38(4), 209. https://doi.org/10.1007/s10396-011-0313-z
Ishikawa, Takuya, et al. "A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography." Journal of medical ultrasonics (2001) vol. 38,4 (2011): 209. doi: https://doi.org/10.1007/s10396-011-0313-z
Ishikawa T, Itoh A, Kawashima H, Ohno E, Matsubara H, Nakamura M, Miyahara R, Ohmiya N, Goto H, Hirooka Y. A case of solid-pseudopapillary neoplasm, focusing on contrast-enhanced endoscopic ultrasonography. J Med Ultrason (2001). 2011 Oct;38(4):209. doi: 10.1007/s10396-011-0313-z. Epub 2011 Jun 17. PMID: 27278586.
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The patient had a normal magnetic resonance imaging and temporal lobe epilepsy secondary to a porencephalic cyst but showed structural lesions (hippocampal sclerosis).

Epilepsy & behavior case reports

Matsubara T, Ayuzawa S, Aoki T, Fujiomto A, Osuka S, Matsumura A.
PMID: 25667851
Epilepsy Behav Case Rep. 2013 Sep 28;1:153-6. doi: 10.1016/j.ebcr.2013.08.005. eCollection 2013.

Patients with a porencephalic cyst frequently develop intractable temporal lobe epilepsy (TLE). We report a surgically-treated male patient with intractable mesial TLE (mTLE) secondary to a porencephalic cyst. Although magnetic resonance imaging showed no hippocampal abnormalities, long-term video-electrocorticography revealed...

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Matsubara T, Ayuzawa S, Aoki T, et al. The patient had a normal magnetic resonance imaging and temporal lobe epilepsy secondary to a porencephalic cyst but showed structural lesions (hippocampal sclerosis). Epilepsy Behav Case Rep. 2013;1:153-6doi: 10.1016/j.ebcr.2013.08.005.
Matsubara, T., Ayuzawa, S., Aoki, T., Fujiomto, A., Osuka, S., & Matsumura, A. (2013). The patient had a normal magnetic resonance imaging and temporal lobe epilepsy secondary to a porencephalic cyst but showed structural lesions (hippocampal sclerosis). Epilepsy & behavior case reports, 1153-6. https://doi.org/10.1016/j.ebcr.2013.08.005
Matsubara, Teppei, et al. "The patient had a normal magnetic resonance imaging and temporal lobe epilepsy secondary to a porencephalic cyst but showed structural lesions (hippocampal sclerosis)." Epilepsy & behavior case reports vol. 1 (2013): 153-6. doi: https://doi.org/10.1016/j.ebcr.2013.08.005
Matsubara T, Ayuzawa S, Aoki T, Fujiomto A, Osuka S, Matsumura A. The patient had a normal magnetic resonance imaging and temporal lobe epilepsy secondary to a porencephalic cyst but showed structural lesions (hippocampal sclerosis). Epilepsy Behav Case Rep. 2013 Sep 28;1:153-6. doi: 10.1016/j.ebcr.2013.08.005. eCollection 2013. PMID: 25667851; PMCID: PMC4150633.
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Showing 1 to 12 of 1607 entries