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Pedunculopontine arousal system physiology - Implications for insomnia.

Sleep science (Sao Paulo, Brazil)

Garcia-Rill E, Luster B, Mahaffey S, Bisagno V, Urbano FJ.
PMID: 26483950
Sleep Sci. 2015 Apr-Jun;8(2):92-9. doi: 10.1016/j.slsci.2015.06.002. Epub 2015 Jul 10.

We consider insomnia a disorder of waking rather than a disorder of sleep. This review examines the role of the reticular activating system, especially the pedunculopontine nucleus, in the symptoms of insomnia, mainly representing an overactive waking drive. We...

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Garcia-Rill E, Luster B, Mahaffey S, et al. Pedunculopontine arousal system physiology - Implications for insomnia. Sleep Sci. 2015;8(2):92-9doi: 10.1016/j.slsci.2015.06.002.
Garcia-Rill, E., Luster, B., Mahaffey, S., Bisagno, V., & Urbano, F. J. (2015). Pedunculopontine arousal system physiology - Implications for insomnia. Sleep science (Sao Paulo, Brazil), 8(2), 92-9. https://doi.org/10.1016/j.slsci.2015.06.002
Garcia-Rill, Edgar, et al. "Pedunculopontine arousal system physiology - Implications for insomnia." Sleep science (Sao Paulo, Brazil) vol. 8,2 (2015): 92-9. doi: https://doi.org/10.1016/j.slsci.2015.06.002
Garcia-Rill E, Luster B, Mahaffey S, Bisagno V, Urbano FJ. Pedunculopontine arousal system physiology - Implications for insomnia. Sleep Sci. 2015 Apr-Jun;8(2):92-9. doi: 10.1016/j.slsci.2015.06.002. Epub 2015 Jul 10. PMID: 26483950; PMCID: PMC4608886.
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Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance .

Clinical proteomics

Mehaffy C, Dobos KM, Nahid P, Kruh-Garcia NA.
PMID: 28592925
Clin Proteomics. 2017 Jun 05;14:21. doi: 10.1186/s12014-017-9156-y. eCollection 2017.

METHODS: Multiple reaction monitoring assays were optimized for the enhanced detection of 41 RESULTS: Our enhanced methods provide limit of detection and quantification averaging in the low femtomolar range for detection of mycobacterial products in serum. At least one...

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Mehaffy C, Dobos KM, Nahid P, et al. Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance . Clin Proteomics. 2017;14:21doi: 10.1186/s12014-017-9156-y.
Mehaffy, C., Dobos, K. M., Nahid, P., & Kruh-Garcia, N. A. (2017). Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance . Clinical proteomics, 1421. https://doi.org/10.1186/s12014-017-9156-y
Mehaffy, Carolina, et al. "Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance ." Clinical proteomics vol. 14 (2017): 21. doi: https://doi.org/10.1186/s12014-017-9156-y
Mehaffy C, Dobos KM, Nahid P, Kruh-Garcia NA. Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance . Clin Proteomics. 2017 Jun 05;14:21. doi: 10.1186/s12014-017-9156-y. eCollection 2017. PMID: 28592925; PMCID: PMC5460347.
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Consumer acceptance and steak cutting yields of beef top sirloin and knuckle subprimals.

Meat science

King DA, Shackelford SD, Wheeler TL, Pfeiffer KD, Mehaffey JM, Miller MF, Nickelson R, Koohmaraie M.
PMID: 20416622
Meat Sci. 2009 Dec;83(4):782-7. doi: 10.1016/j.meatsci.2009.08.021. Epub 2009 Aug 14.

Beef knuckles (n=150) and center-cut top sirloin butts (n=150) were used to determine portion-controlled steak cutting yields, palatability characteristics, and consumer acceptance of rectus femoris (RF), vastus lateralis (VL), and gluteus medius (GM) steaks. Steak yields were higher (P

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King DA, Shackelford SD, Wheeler TL, et al. Consumer acceptance and steak cutting yields of beef top sirloin and knuckle subprimals. Meat Sci. 2009;83(4):782-7doi: 10.1016/j.meatsci.2009.08.021.
King, D. A., Shackelford, S. D., Wheeler, T. L., Pfeiffer, K. D., Mehaffey, J. M., Miller, M. F., Nickelson, R., & Koohmaraie, M. (2009). Consumer acceptance and steak cutting yields of beef top sirloin and knuckle subprimals. Meat science, 83(4), 782-7. https://doi.org/10.1016/j.meatsci.2009.08.021
King, D A, et al. "Consumer acceptance and steak cutting yields of beef top sirloin and knuckle subprimals." Meat science vol. 83,4 (2009): 782-7. doi: https://doi.org/10.1016/j.meatsci.2009.08.021
King DA, Shackelford SD, Wheeler TL, Pfeiffer KD, Mehaffey JM, Miller MF, Nickelson R, Koohmaraie M. Consumer acceptance and steak cutting yields of beef top sirloin and knuckle subprimals. Meat Sci. 2009 Dec;83(4):782-7. doi: 10.1016/j.meatsci.2009.08.021. Epub 2009 Aug 14. PMID: 20416622.
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Cardiac Safety Research Consortium (CSRC): Cardiovascular Safety and Adverse Event Case Report Forms.

Therapeutic innovation & regulatory science

Sabol ME, Finkle J, Krucoff M, Stockbridge N, Parkhill N, Shinagawa K, Mahaffey K, Tcheng J, Lenihan D, Melloni C, Todaro T, Michelson E, Munley J, Zander J, Oh R.
PMID: 30222439
Ther Innov Regul Sci. 2015 Jul;49(4):511-513. doi: 10.1177/2168479014567319.

Detection of off-target cardiovascular (CV) effects remains a significant challenge to drug development. Documentation of CV events in non-CV trials is often inadequate to interpret imbalances between treatment arms, which may lead to concerns about potential CV safety "signals."...

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Sabol ME, Finkle J, Krucoff M, et al. Cardiac Safety Research Consortium (CSRC): Cardiovascular Safety and Adverse Event Case Report Forms. Ther Innov Regul Sci. 2015;49(4):511-513doi: 10.1177/2168479014567319.
Sabol, M. E., Finkle, J., Krucoff, M., Stockbridge, N., Parkhill, N., Shinagawa, K., Mahaffey, K., Tcheng, J., Lenihan, D., Melloni, C., Todaro, T., Michelson, E., Munley, J., Zander, J., & Oh, R. (2015). Cardiac Safety Research Consortium (CSRC): Cardiovascular Safety and Adverse Event Case Report Forms. Therapeutic innovation & regulatory science, 49(4), 511-513. https://doi.org/10.1177/2168479014567319
Sabol, Mary Elizabeth, et al. "Cardiac Safety Research Consortium (CSRC): Cardiovascular Safety and Adverse Event Case Report Forms." Therapeutic innovation & regulatory science vol. 49,4 (2015): 511-513. doi: https://doi.org/10.1177/2168479014567319
Sabol ME, Finkle J, Krucoff M, Stockbridge N, Parkhill N, Shinagawa K, Mahaffey K, Tcheng J, Lenihan D, Melloni C, Todaro T, Michelson E, Munley J, Zander J, Oh R. Cardiac Safety Research Consortium (CSRC): Cardiovascular Safety and Adverse Event Case Report Forms. Ther Innov Regul Sci. 2015 Jul;49(4):511-513. doi: 10.1177/2168479014567319. PMID: 30222439.
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SITS Derivatization of Peptides to Enhance 266 nm Ultraviolet Photodissociation (UVPD).

Journal of the American Society for Mass Spectrometry

Quick MM, Mehaffey MR, Johns RW, Parker WR, Brodbelt JS.
PMID: 28315237
J Am Soc Mass Spectrom. 2017 Jul;28(7):1462-1472. doi: 10.1007/s13361-017-1650-y. Epub 2017 Mar 17.

N-terminal derivatization of peptides with the chromogenic reagent 4-acetamido-4-isothiocyanatostilbene-2,2-disulfonic acid (SITS) is demonstrated to enhance the efficiency of 266 nm ultraviolet photodissociation (UVPD). Attachment of the chromophore results in a mass shift of 454 Da and provides significant gains...

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Quick MM, Mehaffey MR, Johns RW, et al. SITS Derivatization of Peptides to Enhance 266 nm Ultraviolet Photodissociation (UVPD). J Am Soc Mass Spectrom. 2017;28(7):1462-1472doi: 10.1007/s13361-017-1650-y.
Quick, M. M., Mehaffey, M. R., Johns, R. W., Parker, W. R., & Brodbelt, J. S. (2017). SITS Derivatization of Peptides to Enhance 266 nm Ultraviolet Photodissociation (UVPD). Journal of the American Society for Mass Spectrometry, 28(7), 1462-1472. https://doi.org/10.1007/s13361-017-1650-y
Quick, M Montana, et al. "SITS Derivatization of Peptides to Enhance 266 nm Ultraviolet Photodissociation (UVPD)." Journal of the American Society for Mass Spectrometry vol. 28,7 (2017): 1462-1472. doi: https://doi.org/10.1007/s13361-017-1650-y
Quick MM, Mehaffey MR, Johns RW, Parker WR, Brodbelt JS. SITS Derivatization of Peptides to Enhance 266 nm Ultraviolet Photodissociation (UVPD). J Am Soc Mass Spectrom. 2017 Jul;28(7):1462-1472. doi: 10.1007/s13361-017-1650-y. Epub 2017 Mar 17. PMID: 28315237.
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Acute differences in blood lipids and inflammatory biomarkers following controlled exposures to cookstove air pollution in the STOVES study.

International journal of environmental health research

Walker ES, Fedak KM, Good N, Balmes J, Brook RD, Clark ML, Cole-Hunter T, Devlin RB, L'Orange C, Luckasen G, Mehaffy J, Shelton R, Wilson A, Volckens J, Peel JL.
PMID: 32615777
Int J Environ Health Res. 2020 Jul 02;1-14. doi: 10.1080/09603123.2020.1785402. Epub 2020 Jul 02.

Household air pollution is a leading risk factor for morbidity and premature mortality. Numerous cookstoves have been developed to reduce household air pollution, but it is unclear whether such cookstoves meaningfully improve health. In a controlled exposure study with...

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Walker ES, Fedak KM, Good N, et al. Acute differences in blood lipids and inflammatory biomarkers following controlled exposures to cookstove air pollution in the STOVES study. Int J Environ Health Res. 2020;1-14doi: 10.1080/09603123.2020.1785402.
Walker, E. S., Fedak, K. M., Good, N., Balmes, J., Brook, R. D., Clark, M. L., Cole-Hunter, T., Devlin, R. B., L'Orange, C., Luckasen, G., Mehaffy, J., Shelton, R., Wilson, A., Volckens, J., & Peel, J. L. (2020). Acute differences in blood lipids and inflammatory biomarkers following controlled exposures to cookstove air pollution in the STOVES study. International journal of environmental health research, 1-14. https://doi.org/10.1080/09603123.2020.1785402
Walker, Ethan S, et al. "Acute differences in blood lipids and inflammatory biomarkers following controlled exposures to cookstove air pollution in the STOVES study." International journal of environmental health research vol. (2020): 1-14. doi: https://doi.org/10.1080/09603123.2020.1785402
Walker ES, Fedak KM, Good N, Balmes J, Brook RD, Clark ML, Cole-Hunter T, Devlin RB, L'Orange C, Luckasen G, Mehaffy J, Shelton R, Wilson A, Volckens J, Peel JL. Acute differences in blood lipids and inflammatory biomarkers following controlled exposures to cookstove air pollution in the STOVES study. Int J Environ Health Res. 2020 Jul 02;1-14. doi: 10.1080/09603123.2020.1785402. Epub 2020 Jul 02. PMID: 32615777; PMCID: PMC7775880.
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Commentary: Pathoanatomic differences in functional mitral regurgitation-a guide for future interventions?.

The Journal of thoracic and cardiovascular surgery

Hawkins RB, Mehaffey JH.
PMID: 33583582
J Thorac Cardiovasc Surg. 2021 Jan 21; doi: 10.1016/j.jtcvs.2021.01.054. Epub 2021 Jan 21.

No abstract available.

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Hawkins RB, Mehaffey JH. Commentary: Pathoanatomic differences in functional mitral regurgitation-a guide for future interventions?. J Thorac Cardiovasc Surg. 2021;doi: 10.1016/j.jtcvs.2021.01.054.
Hawkins, R. B., & Mehaffey, J. H. (2021). Commentary: Pathoanatomic differences in functional mitral regurgitation-a guide for future interventions?. The Journal of thoracic and cardiovascular surgery, . https://doi.org/10.1016/j.jtcvs.2021.01.054
Hawkins, Robert B, and Mehaffey, J Hunter. "Commentary: Pathoanatomic differences in functional mitral regurgitation-a guide for future interventions?." The Journal of thoracic and cardiovascular surgery vol. (2021). doi: https://doi.org/10.1016/j.jtcvs.2021.01.054
Hawkins RB, Mehaffey JH. Commentary: Pathoanatomic differences in functional mitral regurgitation-a guide for future interventions?. J Thorac Cardiovasc Surg. 2021 Jan 21; doi: 10.1016/j.jtcvs.2021.01.054. Epub 2021 Jan 21. PMID: 33583582.
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Angiotensin II-induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor-alpha type 1 receptor.

Physiological reports

Majid DSA, Mahaffey E, Castillo A, Prieto MC, Navar LG.
PMID: 34427402
Physiol Rep. 2021 Aug;9(16):e14990. doi: 10.14814/phy2.14990.

In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor-alpha (TNF-α) levels increase. However, TNF-α has been shown to suppress AGT formation in cultured renal proximal tubular cells. We...

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Majid DSA, Mahaffey E, Castillo A, et al. Angiotensin II-induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor-alpha type 1 receptor. Physiol Rep. 2021;9(16):e14990doi: 10.14814/phy2.14990.
Majid, D. S. A., Mahaffey, E., Castillo, A., Prieto, M. C., & Navar, L. G. (2021). Angiotensin II-induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor-alpha type 1 receptor. Physiological reports, 9(16), e14990. https://doi.org/10.14814/phy2.14990
Majid, Dewan S A, et al. "Angiotensin II-induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor-alpha type 1 receptor." Physiological reports vol. 9,16 (2021): e14990. doi: https://doi.org/10.14814/phy2.14990
Majid DSA, Mahaffey E, Castillo A, Prieto MC, Navar LG. Angiotensin II-induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor-alpha type 1 receptor. Physiol Rep. 2021 Aug;9(16):e14990. doi: 10.14814/phy2.14990. PMID: 34427402; PMCID: PMC8383705.
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Two Hours of In Vivo Lung Perfusion Improves Lung Function in Sepsis-Induced Acute Respiratory Distress Syndrome.

Seminars in thoracic and cardiovascular surgery

Byler MR, Haywood NS, Money DT, Zhang A, Beller JP, Charles EJ, Chancellor WZ, Ta HQ, Stoler MH, Mehaffey JH, Laubach VE, Kron IL, Roeser ME.
PMID: 33713831
Semin Thorac Cardiovasc Surg. 2021 Mar 11; doi: 10.1053/j.semtcvs.2021.02.034. Epub 2021 Mar 11.

Sepsis is the leading cause of acute respiratory distress syndrome (ARDS) in adults and carries a high mortality. Utilizing a previously validated porcine model of sepsis-induced ARDS, we sought to refine our novel therapeutic technique of in vivo lung...

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Byler MR, Haywood NS, Money DT, et al. Two Hours of In Vivo Lung Perfusion Improves Lung Function in Sepsis-Induced Acute Respiratory Distress Syndrome. Semin Thorac Cardiovasc Surg. 2021;doi: 10.1053/j.semtcvs.2021.02.034.
Byler, M. R., Haywood, N. S., Money, D. T., Zhang, A., Beller, J. P., Charles, E. J., Chancellor, W. Z., Ta, H. Q., Stoler, M. H., Mehaffey, J. H., Laubach, V. E., Kron, I. L., & Roeser, M. E. (2021). Two Hours of In Vivo Lung Perfusion Improves Lung Function in Sepsis-Induced Acute Respiratory Distress Syndrome. Seminars in thoracic and cardiovascular surgery, . https://doi.org/10.1053/j.semtcvs.2021.02.034
Byler, Matthew R, et al. "Two Hours of In Vivo Lung Perfusion Improves Lung Function in Sepsis-Induced Acute Respiratory Distress Syndrome." Seminars in thoracic and cardiovascular surgery vol. (2021). doi: https://doi.org/10.1053/j.semtcvs.2021.02.034
Byler MR, Haywood NS, Money DT, Zhang A, Beller JP, Charles EJ, Chancellor WZ, Ta HQ, Stoler MH, Mehaffey JH, Laubach VE, Kron IL, Roeser ME. Two Hours of In Vivo Lung Perfusion Improves Lung Function in Sepsis-Induced Acute Respiratory Distress Syndrome. Semin Thorac Cardiovasc Surg. 2021 Mar 11; doi: 10.1053/j.semtcvs.2021.02.034. Epub 2021 Mar 11. PMID: 33713831; PMCID: PMC8433279.
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Commentary: The debate continues on optimal myocardial recovery assessment.

The Journal of thoracic and cardiovascular surgery

Hawkins RB, Yarboro LT, Mehaffey JH.
PMID: 33785211
J Thorac Cardiovasc Surg. 2021 Feb 22; doi: 10.1016/j.jtcvs.2021.02.051. Epub 2021 Feb 22.

No abstract available.

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Hawkins RB, Yarboro LT, Mehaffey JH. Commentary: The debate continues on optimal myocardial recovery assessment. J Thorac Cardiovasc Surg. 2021;doi: 10.1016/j.jtcvs.2021.02.051.
Hawkins, R. B., Yarboro, L. T., & Mehaffey, J. H. (2021). Commentary: The debate continues on optimal myocardial recovery assessment. The Journal of thoracic and cardiovascular surgery, . https://doi.org/10.1016/j.jtcvs.2021.02.051
Hawkins, Robert B, et al. "Commentary: The debate continues on optimal myocardial recovery assessment." The Journal of thoracic and cardiovascular surgery vol. (2021). doi: https://doi.org/10.1016/j.jtcvs.2021.02.051
Hawkins RB, Yarboro LT, Mehaffey JH. Commentary: The debate continues on optimal myocardial recovery assessment. J Thorac Cardiovasc Surg. 2021 Feb 22; doi: 10.1016/j.jtcvs.2021.02.051. Epub 2021 Feb 22. PMID: 33785211.
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Barriers and facilitators to postoperative pain management in Rwanda from the perspective of health care providers: A contextualization of the theory of planned behavior.

Canadian journal of pain = Revue canadienne de la douleur

Nyirigira G, Wilson RA, VanDenKerkhof EG, Goldstein DH, Twagirumugabe T, Mahaffey R, Parlow J, Johnson AP.
PMID: 35005369
Can J Pain. 2018 Apr 12;2(1):87-102. doi: 10.1080/24740527.2018.1451251. eCollection 2018.

AIMS: Identify opportunities to improve knowledge translation for post-operative pain management in Rwanda by exploring clinician and environmental factors affecting this practice.METHODS: The theory of planned behavior (TPB) guided development of a questionnaire to measure intent to assess and...

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Nyirigira G, Wilson RA, VanDenKerkhof EG, et al. Barriers and facilitators to postoperative pain management in Rwanda from the perspective of health care providers: A contextualization of the theory of planned behavior. Can J Pain. 2018;2(1):87-102doi: 10.1080/24740527.2018.1451251.
Nyirigira, G., Wilson, R. A., VanDenKerkhof, E. G., Goldstein, D. H., Twagirumugabe, T., Mahaffey, R., Parlow, J., & Johnson, A. P. (2018). Barriers and facilitators to postoperative pain management in Rwanda from the perspective of health care providers: A contextualization of the theory of planned behavior. Canadian journal of pain = Revue canadienne de la douleur, 2(1), 87-102. https://doi.org/10.1080/24740527.2018.1451251
Nyirigira, Gaston, et al. "Barriers and facilitators to postoperative pain management in Rwanda from the perspective of health care providers: A contextualization of the theory of planned behavior." Canadian journal of pain = Revue canadienne de la douleur vol. 2,1 (2018): 87-102. doi: https://doi.org/10.1080/24740527.2018.1451251
Nyirigira G, Wilson RA, VanDenKerkhof EG, Goldstein DH, Twagirumugabe T, Mahaffey R, Parlow J, Johnson AP. Barriers and facilitators to postoperative pain management in Rwanda from the perspective of health care providers: A contextualization of the theory of planned behavior. Can J Pain. 2018 Apr 12;2(1):87-102. doi: 10.1080/24740527.2018.1451251. eCollection 2018. PMID: 35005369; PMCID: PMC8730569.
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Interviews During the Pandemic: A Thoracic Education Cooperative Group and Surgery Residents Project.

The Annals of thoracic surgery

Taylor M, Wallen T, Mehaffey JH, Shirafkan A, Brescia AA, Freeman K, Louis C, Watson J, Okereke I.
PMID: 33774001
Ann Thorac Surg. 2022 Feb;113(2):663-668. doi: 10.1016/j.athoracsur.2021.02.089. Epub 2021 Mar 25.

BACKGROUND: The 2020 interview cycle for cardiothoracic fellowships was affected by the coronavirus-19 pandemic. Many programs shifted from in-person to virtual interviews. We evaluated applicant perceptions of the various formats.METHODS: All 2019-2020 cardiothoracic fellowship applicants received an electronic survey...

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Taylor M, Wallen T, Mehaffey JH, et al. Interviews During the Pandemic: A Thoracic Education Cooperative Group and Surgery Residents Project. Ann Thorac Surg. 2021;113(2):663-668doi: 10.1016/j.athoracsur.2021.02.089.
Taylor, M., Wallen, T., Mehaffey, J. H., Shirafkan, A., Brescia, A. A., Freeman, K., Louis, C., Watson, J., & Okereke, I. (2022). Interviews During the Pandemic: A Thoracic Education Cooperative Group and Surgery Residents Project. The Annals of thoracic surgery, 113(2), 663-668. https://doi.org/10.1016/j.athoracsur.2021.02.089
Taylor, Melissa, et al. "Interviews During the Pandemic: A Thoracic Education Cooperative Group and Surgery Residents Project." The Annals of thoracic surgery vol. 113,2 (2022): 663-668. doi: https://doi.org/10.1016/j.athoracsur.2021.02.089
Taylor M, Wallen T, Mehaffey JH, Shirafkan A, Brescia AA, Freeman K, Louis C, Watson J, Okereke I. Interviews During the Pandemic: A Thoracic Education Cooperative Group and Surgery Residents Project. Ann Thorac Surg. 2022 Feb;113(2):663-668. doi: 10.1016/j.athoracsur.2021.02.089. Epub 2021 Mar 25. PMID: 33774001.
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Showing 1 to 12 of 133 entries