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Showing 1 to 12 of 152 entries
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New platinum(II) complexes with benzo-thia-zole ligands.

Acta crystallographica. Section E, Crystallographic communications

Carmona-Negrón JA, Cádiz ME, Moore CE, Rheingold AL, Meléndez E.
PMID: 27006819
Acta Crystallogr E Crystallogr Commun. 2016 Feb 24;72:412-6. doi: 10.1107/S2056989016002826. eCollection 2016 Mar 01.

Four new platinum(II) complexes, namely tetra-ethyl-ammonium tri-bromido-(2-methyl-1,3-benzo-thia-zole-κN)platinate(II), [NEt4][PtBr3(C8H7NS)] (1), tetra-ethyl-ammonium tri-bromido-(6-meth-oxy-2-methyl-1,3-benzo-thia-zole-κN)platinate(II), [NEt4][PtBr3(C9H9NOS)] (2), tetra-ethyl-ammonium tri-bromido-(2,5,6-trimethyl-1,3-benzo-thia-zole-κN)platinate(II), [NEt4][PtBr3(C10H11NS)] (3), and tetra-ethyl-ammonium tri-bromido-(2-methyl-5-nitro-1,3-benzo-thia-zole-κN)platinate(II), [NEt4][PtBr3(C8H6N2O2S)] (4), have been synthesized and structurally characterized by single-crystal X-ray diffraction techniques. These species are precursors of compounds...

Crystal structure of 16-ferrocenylmethyl-3β-hydroxy-estra-1,3,5(10)-trien-17-one: a potential chemotherapeutic drug.

Acta crystallographica. Section E, Crystallographic communications

Carmona-Negrón JA, Flores-Rivera MM, Díaz-Reyes Z, Moore CE, Rheigold AL, Meléndez E.
PMID: 27308062
Acta Crystallogr E Crystallogr Commun. 2016 May 27;72:868-71. doi: 10.1107/S2056989016008446. eCollection 2016 Jun 01.

A new ferrocene complex, 16-ferrocenylmethyl-3β-hy-droxy-estra-1,3,5(10)-trien-17-one dimethyl sulfoxide monosolvate, [Fe(C5H5)(C24H27O2)]·C2H6OS, has been synthesized and structurally characterized by single-crystal X-ray diffraction techniques. The mol-ecule crystallizes in the space group P21 with one mol-ecule of dimethyl sulfoxide. A hydrogen bond links the...

Formulation and particle size reduction improve bioavailability of poorly water-soluble compounds with antimalarial activity.

Malaria research and treatment

Wang H, Li Q, Reyes S, Zhang J, Xie L, Melendez V, Hickman M, Kozar MP.
PMID: 23766925
Malar Res Treat. 2013;2013:769234. doi: 10.1155/2013/769234. Epub 2013 May 12.

Decoquinate (DQ) is highly effective at killing malaria parasites in vitro; however, it is extremely insoluble in water. In this study, solid dispersion method was used for DQ formulation which created a suitable physical form of DQ in aqueous...

The Gelation of CO(2): A Sustainable Route to the Creation of Microcellular Materials.

Science (New York, N.Y.)

Shi C, Huang Z, Kilic S, Xu J, Enick RM, Beckman EJ, Carr AJ, Melendez RE, Hamilton AD.
PMID: 10567255
Science. 1999 Nov 19;286(5444):1540-1543. doi: 10.1126/science.286.5444.1540.

Compounds with strong thermodynamic affinity for carbon dioxide (CO(2)) have been designed and synthesized that dissolve in CO(2), then associate to form gels. Upon removal of the CO(2), these gels produced free-standing foams with cells with an average diameter...

Synthesis, Solution and Solid State Structure of Titanium-Maltol Complex.

Inorganica chimica acta

Lamboy JL, Pasquale A, Rheingold AL, Meléndez E.
PMID: 18425211
Inorganica Chim Acta. 2007 Apr 20;360(6):2115-2120. doi: 10.1016/j.ica.2006.10.042.

The reaction of Cp(2)TiCl(2) with two equivalents of maltol (3-hydroxy-2-methyl-4-pyrone) in water, at room temperature and pH of 5.4, leads to a complete replacement of Cp and chloride ligands affording, Ti(maltolato)(2)(OH)(2.) The complex has been characterized by IR, NMR...

Temporal evolution of the angular response of a holographic diffraction grating in PVA/acrylamide photopolymer.

Optics express

Gallego S, Ortuno M, Neipp C, Garcia C, Belendez A, Pascual I.
PMID: 19461722
Opt Express. 2003 Jan 27;11(2):181-90. doi: 10.1364/oe.11.000181.

In this paper we evaluate the temporal evolution, after exposure, of a diffraction grating stored in a PVA/acrylamide photopolymer. We also study the overmodulation of the refractive index inside the hologram, which gives rise to a particular behaviour of...

Experimental evidence of mixed gratings with a phase difference between the phase and amplitude grating in volume holograms.

Optics express

Neipp C, Pascual I, Belendez A.
PMID: 19452002
Opt Express. 2002 Nov 18;10(23):1374-83. doi: 10.1364/oe.10.001374.

The Coupled Wave Theory of Kogelnik has given a wellestablished basis for the comprehension of how light propagates inside a hologram. This theory gives an accurate approximation for the diffraction efficiency of volume phase holograms and volume absorption holograms...

Synthesis, characterization and cytotoxic studies of water soluble [(η-C(5)H(5))(2)Mo(thionucleobase/thionucleoside)]Cl complexes in breast and colon cancer cell lines.

Journal of organometallic chemistry

Acevedo-Acevedo D, Matta J, Meléndez E.
PMID: 21399723
J Organomet Chem. 2011 Mar 01;696(5):1032-1037. doi: 10.1016/j.jorganchem.2010.09.053.

Four new water soluble molybdenocene complexes were synthesized in aqueous solution at pH 7.0. The new species, [(η(5)-C(5)H(5))(2)Mo(L)]Cl (L= 6-mercaptopurine, 2-amino-6-mercaptopurine, (-)-2-amino-6-mercaptopurine ribose and 6-mercaptopurine ribose), were characterized by spectroscopic methods. NMR spectroscopic data showed the presence of two...

Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics.

Gene regulation and systems biology

Mansoor M, Melendez AJ.
PMID: 19787090
Gene Regul Syst Bio. 2008 Sep 22;2:275-95. doi: 10.4137/grsb.s418.

Antisense oligonucleotides (As-ODNs) are single stranded, synthetically prepared strands of deoxynucleotide sequences, usually 18-21 nucleotides in length, complementary to the mRNA sequence of the target gene. As-ODNs are able to selectively bind cognate mRNA sequences by sequence-specific hybridization. This...

The power of mentoring leaders. Interview by Kenya D Haney.

Imprint

Burnes L, Melendez G, Schmidt C.
PMID: 20377020
Imprint. 2010 Feb-Mar;57(2):26-9.

No abstract available.

Homozygous deletion of TNFRSF4, TP73, PPAP2B and DPYD at 1p and PDCD5 at 19q identified by multiplex ligation-dependent probe amplification (MLPA) analysis in pediatric anaplastic glioma with questionable oligodendroglial component.

Molecular cytogenetics

Torres-Martín M, Peña-Granero C, Carceller F, Gutiérrez M, Burbano RR, Pinto GR, Castresana JS, Melendez B, Rey JA.
PMID: 24387276
Mol Cytogenet. 2014 Jan 06;7(1):1. doi: 10.1186/1755-8166-7-1.

BACKGROUND: Pediatric oligodendrogliomas are rare and appear to show a different molecular profile from adult tumors. Some gliomas display allelic losses at 1p/19q in pediatric patients, although less frequently than in adult patients, but this is rare in tumors...

Theoretical and experimental spectroscopic analysis of cyano-substituted styrylpyridine compounds.

International journal of molecular sciences

Castro ME, Percino MJ, Chapela VM, Ceron M, Soriano-Moro G, Lopez-Cruz J, Melendez FJ.
PMID: 23429190
Int J Mol Sci. 2013 Feb 18;14(2):4005-29. doi: 10.3390/ijms14024005.

A combined theoretical and experimental study on the structure, infrared, UV-Vis and 1H NMR data of trans-2-(m-cyanostyryl)pyridine, trans-2-[3-methyl-(m-cyanostyryl)]pyridine and trans-4-(m-cyanostyryl)pyridine is presented. The synthesis was carried out with an efficient Knoevenagel condensation using green chemistry conditions. Theoretical geometry optimizations...

Showing 1 to 12 of 152 entries