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Autoimmune liver disease: news and perspectives.

Translational medicine @ UniSa

Mieli-Vergani G, Vergani D.
PMID: 23905033
Transl Med UniSa. 2011 Oct 17;1:195-212. Print 2011 Sep.

Autoimmune liver disorders in childhood include autoimmune hepatitis and autoimmune sclerosing cholangitis. These inflammatory liver disorders are characterised histologically by interface hepatitis, biochemically by elevated transaminase levels and serologically by autoantibodies and increased levels of immunoglobulin G. Autoimmune hepatitis...

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Mieli-Vergani G, Vergani D. Autoimmune liver disease: news and perspectives. Transl Med UniSa. 2011;1:195-212
Mieli-Vergani, G., & Vergani, D. (2011). Autoimmune liver disease: news and perspectives. Translational medicine @ UniSa, 1195-212.
Mieli-Vergani, Giorgina, and Vergani, Diego. "Autoimmune liver disease: news and perspectives." Translational medicine @ UniSa vol. 1 (2011): 195-212.
Mieli-Vergani G, Vergani D. Autoimmune liver disease: news and perspectives. Transl Med UniSa. 2011 Oct 17;1:195-212. Print 2011 Sep. PMID: 23905033; PMCID: PMC3728841.
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Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies.

Hepatology communications

Bull LN, Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Dodge JL, Emerick K, Wanty C, Wali S, Blanchard S, Lacaille F, Byrne JA, van Eerde AM, Kolho KL, Houwen R, Lobritto S, Hupertz V, McClean P, Mieli-Vergani G, Sokal E, Rosenthal P, Whitington PF, Pawlowska J, Thompson RJ.
PMID: 29761168
Hepatol Commun. 2018 Mar 30;2(5):515-528. doi: 10.1002/hep4.1168. eCollection 2018 May.

Progressive familial intrahepatic cholestasis (PFIC) with normal circulating gamma-glutamyl transpeptidase levels can result from mutations in the

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Bull LN, Pawlikowska L, Strautnieks S, et al. Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies. Hepatol Commun. 2018;2(5):515-528doi: 10.1002/hep4.1168.
Bull, L. N., Pawlikowska, L., Strautnieks, S., Jankowska, I., Czubkowski, P., Dodge, J. L., Emerick, K., Wanty, C., Wali, S., Blanchard, S., Lacaille, F., Byrne, J. A., van Eerde, A. M., Kolho, K. L., Houwen, R., Lobritto, S., Hupertz, V., McClean, P., Mieli-Vergani, G., Sokal, E., Rosenthal, P., Whitington, P. F., Pawlowska, J., & Thompson, R. J. (2018). Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies. Hepatology communications, 2(5), 515-528. https://doi.org/10.1002/hep4.1168
Bull, Laura N, et al. "Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies." Hepatology communications vol. 2,5 (2018): 515-528. doi: https://doi.org/10.1002/hep4.1168
Bull LN, Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Dodge JL, Emerick K, Wanty C, Wali S, Blanchard S, Lacaille F, Byrne JA, van Eerde AM, Kolho KL, Houwen R, Lobritto S, Hupertz V, McClean P, Mieli-Vergani G, Sokal E, Rosenthal P, Whitington PF, Pawlowska J, Thompson RJ. Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies. Hepatol Commun. 2018 Mar 30;2(5):515-528. doi: 10.1002/hep4.1168. eCollection 2018 May. PMID: 29761168; PMCID: PMC5944593.
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Atovaquone/proguanil-induced autoimmune-like hepatitis.

Hepatology communications

Terziroli Beretta-Piccoli B, Mieli-Vergani G, Bertoli R, Mazzucchelli L, Nofziger C, Paulmichl M, Vergani D.
PMID: 29404460
Hepatol Commun. 2017 May 08;1(4):293-298. doi: 10.1002/hep4.1039. eCollection 2017 Jun.

We report a novel association between the commonly used antimalarial medication atovaquone/proguanil and drug-induced autoimmune-like hepatitis. The patient developed severe liver disease fulfilling biochemical, immunologic, and histologic criteria for the diagnosis of autoimmune hepatitis after the inadvertent rechallenge with...

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Terziroli Beretta-Piccoli B, Mieli-Vergani G, Bertoli R, et al. Atovaquone/proguanil-induced autoimmune-like hepatitis. Hepatol Commun. 2017;1(4):293-298doi: 10.1002/hep4.1039.
Terziroli Beretta-Piccoli, B., Mieli-Vergani, G., Bertoli, R., Mazzucchelli, L., Nofziger, C., Paulmichl, M., & Vergani, D. (2017). Atovaquone/proguanil-induced autoimmune-like hepatitis. Hepatology communications, 1(4), 293-298. https://doi.org/10.1002/hep4.1039
Terziroli Beretta-Piccoli, Benedetta, et al. "Atovaquone/proguanil-induced autoimmune-like hepatitis." Hepatology communications vol. 1,4 (2017): 293-298. doi: https://doi.org/10.1002/hep4.1039
Terziroli Beretta-Piccoli B, Mieli-Vergani G, Bertoli R, Mazzucchelli L, Nofziger C, Paulmichl M, Vergani D. Atovaquone/proguanil-induced autoimmune-like hepatitis. Hepatol Commun. 2017 May 08;1(4):293-298. doi: 10.1002/hep4.1039. eCollection 2017 Jun. PMID: 29404460; PMCID: PMC5721398.
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Real-world management of juvenile autoimmune liver disease.

United European gastroenterology journal

de Boer YS, Liberal R, Vergani D, Mieli-Vergani G.
PMID: 30228891
United European Gastroenterol J. 2018 Aug;6(7):1032-1038. doi: 10.1177/2050640618768922. Epub 2018 Mar 30.

BACKGROUND AND AIMS: Juvenile autoimmune liver disease (JAILD) includes paediatric forms of autoimmune hepatitis (AIH) and autoimmune sclerosing cholangitis (ASC). Since evidence is scarce, there are currently no evidence-based management guidelines for juvenile AIH. This survey was carried out...

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de Boer YS, Liberal R, Vergani D, et al. Real-world management of juvenile autoimmune liver disease. United European Gastroenterol J. 2018;6(7):1032-1038doi: 10.1177/2050640618768922.
de Boer, Y. S., Liberal, R., Vergani, D., & Mieli-Vergani, G. (2018). Real-world management of juvenile autoimmune liver disease. United European gastroenterology journal, 6(7), 1032-1038. https://doi.org/10.1177/2050640618768922
de Boer, Y S, et al. "Real-world management of juvenile autoimmune liver disease." United European gastroenterology journal vol. 6,7 (2018): 1032-1038. doi: https://doi.org/10.1177/2050640618768922
de Boer YS, Liberal R, Vergani D, Mieli-Vergani G. Real-world management of juvenile autoimmune liver disease. United European Gastroenterol J. 2018 Aug;6(7):1032-1038. doi: 10.1177/2050640618768922. Epub 2018 Mar 30. PMID: 30228891; PMCID: PMC6137590.
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Reply.

The Journal of pediatrics

Samyn M, Hensel K, Hadzic N, Mieli-Vergani G.
PMID: 34530024
J Pediatr. 2022 Jan;240:317-318. doi: 10.1016/j.jpeds.2021.09.011. Epub 2021 Sep 13.

No abstract available.

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Samyn M, Hensel K, Hadzic N, et al. Reply. J Pediatr. 2021;240:317-318doi: 10.1016/j.jpeds.2021.09.011.
Samyn, M., Hensel, K., Hadzic, N., & Mieli-Vergani, G. (2022). Reply. The Journal of pediatrics, 240317-318. https://doi.org/10.1016/j.jpeds.2021.09.011
Samyn, Marianne, et al. "Reply." The Journal of pediatrics vol. 240 (2022): 317-318. doi: https://doi.org/10.1016/j.jpeds.2021.09.011
Samyn M, Hensel K, Hadzic N, Mieli-Vergani G. Reply. J Pediatr. 2022 Jan;240:317-318. doi: 10.1016/j.jpeds.2021.09.011. Epub 2021 Sep 13. PMID: 34530024.
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Autoimmune hepatitis.

Current opinion in gastroenterology

Vergani D, Mieli-Vergani G.
PMID: 17031219
Curr Opin Gastroenterol. 2001 Nov;17(6):562-7. doi: 10.1097/00001574-200111000-00014.

Autoimmune liver disease encompasses several disorders (Table 1). Autoimmune hepatitis (AIH) affects mainly women and is characterized histologically by a portal tract mononuclear cell infiltrate disrupting the limiting plate and invading the parenchyma ("interface hepatitis") and serologically by the...

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Vergani D, Mieli-Vergani G. Autoimmune hepatitis. Curr Opin Gastroenterol. 2001;17(6):562-7doi: 10.1097/00001574-200111000-00014.
Vergani, D., & Mieli-Vergani, G. (2001). Autoimmune hepatitis. Current opinion in gastroenterology, 17(6), 562-7. https://doi.org/10.1097/00001574-200111000-00014
Vergani, D, and Mieli-Vergani, G. "Autoimmune hepatitis." Current opinion in gastroenterology vol. 17,6 (2001): 562-7. doi: https://doi.org/10.1097/00001574-200111000-00014
Vergani D, Mieli-Vergani G. Autoimmune hepatitis. Curr Opin Gastroenterol. 2001 Nov;17(6):562-7. doi: 10.1097/00001574-200111000-00014. PMID: 17031219.
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Autoimmune hepatitis in childhood.

Clinical liver disease

Mieli-Vergani G, Vergani D.
PMID: 30992879
Clin Liver Dis (Hoboken). 2014 Feb 10;3(1):6-8. doi: 10.1002/cld.296. eCollection 2014 Jan.

No abstract available.

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Mieli-Vergani G, Vergani D. Autoimmune hepatitis in childhood. Clin Liver Dis (Hoboken). 2014;3(1):6-8doi: 10.1002/cld.296.
Mieli-Vergani, G., & Vergani, D. (2014). Autoimmune hepatitis in childhood. Clinical liver disease, 3(1), 6-8. https://doi.org/10.1002/cld.296
Mieli-Vergani, Giorgina, and Vergani, Diego. "Autoimmune hepatitis in childhood." Clinical liver disease vol. 3,1 (2014): 6-8. doi: https://doi.org/10.1002/cld.296
Mieli-Vergani G, Vergani D. Autoimmune hepatitis in childhood. Clin Liver Dis (Hoboken). 2014 Feb 10;3(1):6-8. doi: 10.1002/cld.296. eCollection 2014 Jan. PMID: 30992879; PMCID: PMC6448691.
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Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry.

Hepatology (Baltimore, Md.)

Ma Y, Su H, Yuksel M, Longhi MS, McPhail MJ, Wang P, Bansal S, Wong GW, Graham J, Yang L, J Thompson R, Doherty DG, Hadzic N, Zen Y, Quaglia A, Heneghan MA, Samyn M, Vergani D, Mieli-Vergani G.
PMID: 33971035
Hepatology. 2021 Oct;74(4):2032-2046. doi: 10.1002/hep.31893. Epub 2021 Jun 21.

BACKGROUND AND AIMS: Genetic predisposition to autoimmune hepatitis (AIH) in adults is associated with possession of human leukocyte antigen (HLA) class I (A*01, B*08) and class II (DRB1*03, -04, -07, or -13) alleles, depending on geographic region. Juvenile autoimmune...

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Ma Y, Su H, Yuksel M, et al. Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry. Hepatology. 2021;74(4):2032-2046doi: 10.1002/hep.31893.
Ma, Y., Su, H., Yuksel, M., Longhi, M. S., McPhail, M. J., Wang, P., Bansal, S., Wong, G. W., Graham, J., Yang, L., J Thompson, R., Doherty, D. G., Hadzic, N., Zen, Y., Quaglia, A., Heneghan, M. A., Samyn, M., Vergani, D., & Mieli-Vergani, G. (2021). Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry. Hepatology (Baltimore, Md.), 74(4), 2032-2046. https://doi.org/10.1002/hep.31893
Ma, Yun, et al. "Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry." Hepatology (Baltimore, Md.) vol. 74,4 (2021): 2032-2046. doi: https://doi.org/10.1002/hep.31893
Ma Y, Su H, Yuksel M, Longhi MS, McPhail MJ, Wang P, Bansal S, Wong GW, Graham J, Yang L, J Thompson R, Doherty DG, Hadzic N, Zen Y, Quaglia A, Heneghan MA, Samyn M, Vergani D, Mieli-Vergani G. Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry. Hepatology. 2021 Oct;74(4):2032-2046. doi: 10.1002/hep.31893. Epub 2021 Jun 21. PMID: 33971035; PMCID: PMC8463472.
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Cutting edge issues in juvenile sclerosing cholangitis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Giorgio AD, Vergani D, Mieli-Vergani G.
PMID: 34289942
Dig Liver Dis. 2021 Jul 18; doi: 10.1016/j.dld.2021.06.028. Epub 2021 Jul 18.

Sclerosing cholangitis (SC) is a rare chronic disorder characterised by inflammation and progressive obliterative fibrosis of the intrahepatic and/or extrahepatic bile ducts. Diagnosis is based on cholangiogram showing bile duct dilatation, narrowing and obliteration of the biliary tree, and...

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Giorgio AD, Vergani D, Mieli-Vergani G. Cutting edge issues in juvenile sclerosing cholangitis. Dig Liver Dis. 2021;doi: 10.1016/j.dld.2021.06.028.
Giorgio, A. D., Vergani, D., & Mieli-Vergani, G. (2021). Cutting edge issues in juvenile sclerosing cholangitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, . https://doi.org/10.1016/j.dld.2021.06.028
Giorgio, Angelo Di, et al. "Cutting edge issues in juvenile sclerosing cholangitis." Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver vol. (2021). doi: https://doi.org/10.1016/j.dld.2021.06.028
Giorgio AD, Vergani D, Mieli-Vergani G. Cutting edge issues in juvenile sclerosing cholangitis. Dig Liver Dis. 2021 Jul 18; doi: 10.1016/j.dld.2021.06.028. Epub 2021 Jul 18. PMID: 34289942.
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A reasoned approach to the treatment of autoimmune hepatitis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Vergani D, Terziroli Beretta-Piccoli B, Mieli-Vergani G.
PMID: 34162505
Dig Liver Dis. 2021 Nov;53(11):1381-1393. doi: 10.1016/j.dld.2021.05.033. Epub 2021 Jun 23.

Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease affecting all ages, characterised by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis on histology and good response to immunosuppressive treatment. If untreated, it has a poor prognosis....

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Vergani D, Terziroli Beretta-Piccoli B, Mieli-Vergani G. A reasoned approach to the treatment of autoimmune hepatitis. Dig Liver Dis. 2021;53(11):1381-1393doi: 10.1016/j.dld.2021.05.033.
Vergani, D., Terziroli Beretta-Piccoli, B., & Mieli-Vergani, G. (2021). A reasoned approach to the treatment of autoimmune hepatitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 53(11), 1381-1393. https://doi.org/10.1016/j.dld.2021.05.033
Vergani, Diego, et al. "A reasoned approach to the treatment of autoimmune hepatitis." Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver vol. 53,11 (2021): 1381-1393. doi: https://doi.org/10.1016/j.dld.2021.05.033
Vergani D, Terziroli Beretta-Piccoli B, Mieli-Vergani G. A reasoned approach to the treatment of autoimmune hepatitis. Dig Liver Dis. 2021 Nov;53(11):1381-1393. doi: 10.1016/j.dld.2021.05.033. Epub 2021 Jun 23. PMID: 34162505.
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Regulatory T cells in autoimmune hepatitis: an updated overview.

Journal of autoimmunity

Longhi MS, Mieli-Vergani G, Vergani D.
PMID: 33652348
J Autoimmun. 2021 May;119:102619. doi: 10.1016/j.jaut.2021.102619. Epub 2021 Feb 27.

Regulatory T-cells (Tregs) are key players in the maintenance of immune homeostasis by preventing immune responses to self-antigens. Defects in Treg frequency and/or function result in overwhelming CD4 and CD8 T cell immune responses participating in the autoimmune attack....

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Longhi MS, Mieli-Vergani G, Vergani D. Regulatory T cells in autoimmune hepatitis: an updated overview. J Autoimmun. 2021;119:102619doi: 10.1016/j.jaut.2021.102619.
Longhi, M. S., Mieli-Vergani, G., & Vergani, D. (2021). Regulatory T cells in autoimmune hepatitis: an updated overview. Journal of autoimmunity, 119102619. https://doi.org/10.1016/j.jaut.2021.102619
Longhi, Maria Serena, et al. "Regulatory T cells in autoimmune hepatitis: an updated overview." Journal of autoimmunity vol. 119 (2021): 102619. doi: https://doi.org/10.1016/j.jaut.2021.102619
Longhi MS, Mieli-Vergani G, Vergani D. Regulatory T cells in autoimmune hepatitis: an updated overview. J Autoimmun. 2021 May;119:102619. doi: 10.1016/j.jaut.2021.102619. Epub 2021 Feb 27. PMID: 33652348; PMCID: PMC8044040.
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Reply.

The Journal of pediatrics

Samyn M, Hensel K, Hadzic N, Mieli-Vergani G.
PMID: 34530024
J Pediatr. 2021 Sep 13; doi: 10.1016/j.jpeds.2021.09.011. Epub 2021 Sep 13.

No abstract available.

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Samyn M, Hensel K, Hadzic N, et al. Reply. J Pediatr. 2021;doi: 10.1016/j.jpeds.2021.09.011.
Samyn, M., Hensel, K., Hadzic, N., & Mieli-Vergani, G. (2021). Reply. The Journal of pediatrics, . https://doi.org/10.1016/j.jpeds.2021.09.011
Samyn, Marianne, et al. "Reply." The Journal of pediatrics vol. (2021). doi: https://doi.org/10.1016/j.jpeds.2021.09.011
Samyn M, Hensel K, Hadzic N, Mieli-Vergani G. Reply. J Pediatr. 2021 Sep 13; doi: 10.1016/j.jpeds.2021.09.011. Epub 2021 Sep 13. PMID: 34530024.
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Showing 1 to 12 of 25 entries