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Showing 1 to 12 of 92 entries
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Progression after spontaneous regression in lung large cell neuroendocrine carcinoma: Report of a curative resection.

Thoracic cancer

Tomizawa K, Suda K, Takemoto T, Iwasaki T, Sakaguchi M, Kuwano H, Mitsudomi T.
PMID: 26443884
Thorac Cancer. 2015 Sep;6(5):655-8. doi: 10.1111/1759-7714.12201. Epub 2015 Jan 08.

We present the first reported case of lung large cell neuroendocrine carcinoma (LCNEC) with spontaneous regression followed by progression. An 85-year-old woman presented with a 2.8-cm nodule in the right upper lung lobe on chest computed tomography. After four...

New Routes for Refinery of Biogenic Platform Chemicals Catalyzed by Cerium Oxide-supported Ruthenium Nanoparticles in Water.

Scientific reports

Mizugaki T, Togo K, Maeno Z, Mitsudome T, Jitsukawa K, Kaneda K.
PMID: 29070900
Sci Rep. 2017 Oct 25;7(1):14007. doi: 10.1038/s41598-017-14373-1.

Highly selective hydrogenative carbon-carbon bond scission of biomass-derived platform oxygenates was achieved with a cerium oxide-supported ruthenium nanoparticle catalyst in water. The present catalyst enabled the selective cleavage of carbon-carbon σ bonds adjacent to carboxyl, ester, and hydroxymethyl groups,...

Highly atom-efficient oxidation of electron-deficient internal olefins to ketones using a palladium catalyst.

Angewandte Chemie (International ed. in English)

Mitsudome T, Yoshida S, Mizugaki T, Jitsukawa K, Kaneda K.
PMID: 23610030
Angew Chem Int Ed Engl. 2013 Jun 03;52(23):5961-4. doi: 10.1002/anie.201301611. Epub 2013 Apr 22.

A 100% atom-efficient synthesis of ketones from electron-deficient internal olefins was achieved using O2 as a "green" oxidant (see scheme, DMA=N,N-dimethylacetamide, EWG=electron-withdrawing group). Various electron-deficient olefins were oxidized to the corresponding ketones with over 99% selectivity and without the...

Montmorillonite-entrapped sub-nanoordered Pd clusters as a heterogeneous catalyst for allylic substitution reactions.

Angewandte Chemie (International ed. in English)

Mitsudome T, Nose K, Mori K, Mizugaki T, Ebitani K, Jitsukawa K, Kaneda K.
PMID: 17378004
Angew Chem Int Ed Engl. 2007;46(18):3288-90. doi: 10.1002/anie.200604644.

No abstract available.

Supported gold nanoparticle catalyst for the selective oxidation of silanes to silanols in water.

Chemical communications (Cambridge, England)

Mitsudome T, Noujima A, Mizugaki T, Jitsukawa K, Kaneda K.
PMID: 19707653
Chem Commun (Camb). 2009 Sep 21;(35):5302-4. doi: 10.1039/b910208f. Epub 2009 Jul 23.

Hydroxyapatite-supported gold nanoparticles (AuHAP) can act as highly efficient and reusable catalysts for the oxidation of diverse silanes into silanols in water; this is the first catalytic methodology for the selective synthesis of aliphatic silanols using water under organic-solvent-free...

Honoring the Past, Embracing the Present, You Are the Future.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Scagliotti GV, Mitsudomi T, Mesko D.
PMID: 30850303
J Thorac Oncol. 2019 Apr;14(4):571-573. doi: 10.1016/j.jtho.2019.01.012. Epub 2019 Mar 06.

No abstract available.

Synthesis and Structural Analysis of (Imido)vanadium Dichloride Complexes Containing 2-(2'-Benz-imidazolyl)pyridine Ligands: Effect of Al Cocatalyst for Efficient Ethylene (Co)polymerization.

ACS omega

Nomura K, Oshima M, Mitsudome T, Harakawa H, Hao P, Tsutsumi K, Nagai G, Ina T, Takaya H, Sun WH, Yamazoe S.
PMID: 31457397
ACS Omega. 2017 Dec 06;2(12):8660-8673. doi: 10.1021/acsomega.7b01225. eCollection 2017 Dec 31.

(Imido)vanadium(V) dichloride complexes containing 2-(2'-benzimidazolyl)-6-methylpyridine ligand (L) of type V(NR)Cl

Mild Hydrogenation of Amides to Amines over a Platinum-Vanadium Bimetallic Catalyst.

Angewandte Chemie (International ed. in English)

Mitsudome T, Miyagawa K, Maeno Z, Mizugaki T, Jitsukawa K, Yamasaki J, Kitagawa Y, Kaneda K.
PMID: 28649715
Angew Chem Int Ed Engl. 2017 Aug 01;56(32):9381-9385. doi: 10.1002/anie.201704199. Epub 2017 Jul 06.

Hydrogenation of amides to amines is an important reaction, but the need for high temperatures and H

Inter-tumor heterogeneity of PD-L1 status: is it important in clinical decision making?.

Journal of thoracic disease

Suda K, Mitsudomi T.
PMID: 32642082
J Thorac Dis. 2020 May;12(5):1770-1775. doi: 10.21037/jtd-20-1661.

No abstract available.

Integrin-linked kinase pathway in heterogeneous pulmonary sarcomatoid carcinoma.

Oncology letters

Shimizu S, Sakai K, Chikugo T, Satou T, Shiraishi N, Mitsudomi T, Nishio K.
PMID: 33692852
Oncol Lett. 2021 Apr;21(4):320. doi: 10.3892/ol.2021.12582. Epub 2021 Feb 23.

Pulmonary sarcomatoid carcinoma (PSC) is classified as poorly differentiated, and non-small cell lung carcinomas that contained a component of sarcoma or sarcoma-like differentiation are rare. The underlying carcinogenetic mechanism governing PSC remains unclear. The current study investigated the underlying...

Activity and mechanism of acquired resistance to tarloxotinib in .

Translational lung cancer research

Koga T, Suda K, Nishino M, Fujino T, Ohara S, Hamada A, Soh J, Tirunagaru V, Vellanki A, Doebele RC, Mitsudomi T.
PMID: 34584864
Transl Lung Cancer Res. 2021 Aug;10(8):3659-3670. doi: 10.21037/tlcr-21-216.

METHODS: Growth inhibitory assays were performed with tarloxotinib-E and its prodrug using Ba/F3 cells expressing one of six RESULTS: Tarloxotinib-E showed potent activity against CONCLUSIONS: Tarloxotinib-E exhibited potent activity against cell line models with

Ni.

Chemistry (Weinheim an der Bergstrasse, Germany)

Fujita S, Yamaguchi S, Yamasaki J, Nakajima K, Yamazoe S, Mizugaki T, Mitsudome T.
PMID: 33283374
Chemistry. 2021 Mar 01;27(13):4439-4446. doi: 10.1002/chem.202005037. Epub 2021 Feb 03.

Non-noble metal-based hydrogenation catalysts have limited practical applications because they exhibit low activity, require harsh reaction conditions, and are unstable in air. To overcome these limitations, herein we propose the alloying of non-noble metal nanoparticles with phosphorus as a...

Showing 1 to 12 of 92 entries