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Showing 1 to 12 of 129 entries
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Controllable yawning expressed as focal seizures of frontal lobe epilepsy.

Epilepsy & behavior case reports

Wasade VS, Balki I, Bowyer SM, Gaddam S, Mohammadi-Nejad AR, Nazem-Zadeh MR, Soltanian-Zadeh H, Zillgitt A, Spanaki-Varelas M.
PMID: 27668178
Epilepsy Behav Case Rep. 2016 Aug 26;6:61-3. doi: 10.1016/j.ebcr.2016.08.005. eCollection 2016.

Excessive yawning was described in some neurological conditions as part of periictal or ictal manifestations of epilepsy, most commonly temporal lobe. We present the first case of controllable yawning as a primary seizure semiology with dominant frontal lobe involvement...

Sustained release Curcumin loaded Solid Lipid Nanoparticles.

Advanced pharmaceutical bulletin

Jourghanian P, Ghaffari S, Ardjmand M, Haghighat S, Mohammadnejad M.
PMID: 27123413
Adv Pharm Bull. 2016 Mar;6(1):17-21. doi: 10.15171/apb.2016.004. Epub 2016 Mar 17.

PURPOSE: curcumin is poorly water soluble drug with low bioavailability. Use of lipid systems in lipophilic substances increases solubility and bioavailability of poorly soluble drugs. The aim of this study was to prepare curcumin loaded Solid Lipid Nanoparticles (SLNs)...

Cytotoxic effects of alcoholic extract of dorema glabrum seed on cancerous cells viability.

Advanced pharmaceutical bulletin

Bannazadeh Amirkhiz M, Rashtchizadeh N, Nazemieh H, Abdolalizadeh J, Mohammadnejad L, Baradaran B.
PMID: 24312867
Adv Pharm Bull. 2013;3(2):403-8. doi: 10.5681/apb.2013.064. Epub 2013 Aug 20.

PURPOSE: In the present study cytotoxic effects of the alcoholic extract of Dorema Glabrum seed on viability of WEHI-164 cells, mouse Fibrosarcoma cell line and L929 normal cells were compared with the cytotoxic effects of Taxol (anticancer and apoptosis...

Mediterranean Fever gene analysis in the azeri turk population with familial mediterranean Fever: evidence for new mutations associated with disease.

Cell journal

Mohammadnejad L, Farajnia S.
PMID: 23862117
Cell J. 2013;15(2):152-9. Epub 2013 Jul 02.

OBJECTIVE: Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent febrile attacks accompanied by serosal and synovial membrane inflammation. FMF is caused by mutations in the MEFV gene and are found usually among Mediterranean populations, Armenians,...

The comparative effects of atorvastatin and quince leaf extract on atherosclerosis.

Iranian Red Crescent medical journal

Khademi F, Danesh B, Mohammad Nejad D, Soleimani Rad J.
PMID: 24578828
Iran Red Crescent Med J. 2013 Aug;15(8):639-43. doi: 10.5812/ircmj.4030. Epub 2013 Aug 05.

BACKGROUND: This study investigates the ability of quince leaf extract to prevent progression of atherosclerosis and to determine the lipid-lowering effect of it.OBJECTIVES: This study suggested that quince leaf effects on progression of atherosclerosis, and performed comparison with atorvastatin...

Neuroprotective effects of Rosa damascena extract on learning and memory in a rat model of amyloid-β-induced Alzheimer's disease.

Advanced biomedical research

Esfandiary E, Karimipour M, Mardani M, Ghanadian M, Alaei HA, Mohammadnejad D, Esmaeili A.
PMID: 26322279
Adv Biomed Res. 2015 Jul 27;4:131. doi: 10.4103/2277-9175.161512. eCollection 2015.

BACKGROUND: Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease, which is characterized clinically by serious impairment in memory and cognition. Current medications only slow down the dementia progression and the present treatment one-drug one-target paradigm for anti-AD treatment...

Evaluation of different direct and indirect SELEX monitoring methods and implementation of melt-curve analysis for rapid discrimination of variant aptamer sequences.

Analytical methods : advancing methods and applications

Mohammadinezhad R, Jalali SAH, Farahmand H.
PMID: 32676627
Anal Methods. 2020 Aug 14;12(30):3823-3835. doi: 10.1039/d0ay00491j. Epub 2020 Jul 17.

Systematic Evolution of Ligands by Exponential enrichment (SELEX) is an iterative method for in vitro selection of aptamers from a random synthetic oligonucleotide library. Successful retrieving of aptamers by SELEX relies on optimization of various steps including target immobilization,...

Health Concerns of Various Nanoparticles: A Review of Their in Vitro and in Vivo Toxicity.

Nanomaterials (Basel, Switzerland)

Ajdary M, Moosavi MA, Rahmati M, Falahati M, Mahboubi M, Mandegary A, Jangjoo S, Mohammadinejad R, Varma RS.
PMID: 30134524
Nanomaterials (Basel). 2018 Aug 21;8(9). doi: 10.3390/nano8090634.

Nanoparticles (NPs) are currently used in diagnosis and treatment of many human diseases, including autoimmune diseases and cancer. However, cytotoxic effects of NPs on normal cells and living organs is a severe limiting factor that hinders their use in...

Evaluation of mitochondrial dysfunction due to oxidative stress in therapeutic, toxic and lethal concentrations of tramadol.

Toxicology research

Mohammadnejad L, Soltaninejad K, Seyedabadi M, Ghasem Pouri SK, Shokrzadeh M, Mohammadi H.
PMID: 34956619
Toxicol Res (Camb). 2021 Nov 08;10(6):1162-1170. doi: 10.1093/toxres/tfab096. eCollection 2021 Dec.

Tramadol (TR) is a centrally acting analgesic drug that is used to relieve pain. The therapeutic (0.1-0.8 mg/l), toxic (1-2 mg/l) and lethal (>2 mg/l) ranges were reported for TR. The present study was designed to evaluate which doses...

Antimicrobial resistance pattern in healthcare-associated infections: investigation of in-hospital risk factors.

Iranian journal of microbiology

Meybodi MME, Foroushani AR, Zolfaghari M, Abdollahi A, Alipour A, Mohammadnejad E, Mehrjardi EZ, Seifi A.
PMID: 34540152
Iran J Microbiol. 2021 Apr;13(2):178-182. doi: 10.18502/ijm.v13i2.5978.

BACKGROUND AND OBJECTIVES: Antimicrobial resistance (AMR) is an increasing threat for efficient treatment of infections. Determining the epidemiology of healthcare-associated infections and causative agents in various hospital wards helps appropriate selection of antimicrobial agents.MATERIALS AND METHODS: This retrospective study...

Nobiletin in Cancer Therapy: How This Plant Derived-Natural Compound Targets Various Oncogene and Onco-Suppressor Pathways.

Biomedicines

Ashrafizadeh M, Zarrabi A, Saberifar S, Hashemi F, Hushmandi K, Hashemi F, Moghadam ER, Mohammadinejad R, Najafi M, Garg M.
PMID: 32380783
Biomedicines. 2020 May 05;8(5). doi: 10.3390/biomedicines8050110.

Cancer therapy is a growing field, and annually, a high number of research is performed to develop novel antitumor drugs. Attempts to find new antitumor drugs continue, since cancer cells are able to acquire resistance to conventional drugs. Natural...

Protective Effect of Resveratrol against Glioblastoma: A Review.

Anti-cancer agents in medicinal chemistry

Ashrafizadeh M, Mohammadinejad R, Farkhondeh T, Samarghandian S.
PMID: 32990542
Anticancer Agents Med Chem. 2021;21(10):1216-1227. doi: 10.2174/1871520620666200929151139.

BACKGROUND: One of the most common tumors of the central nervous system is Glioblastoma (GBM).OBJECTIVE: There is not still an appropriate cure for this malignant tumor. Plant-derived natural products have demonstrated great potential in cancer therapy, and Resveratrol (Res)...

Showing 1 to 12 of 129 entries