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Showing 1 to 12 of 257 entries
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Invasive candidiasis in non neutropenic critically ill - need for region-specific management guidelines.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

Ahmed A, Azim A, Baronia AK, Marak RS, Gurjar M.
PMID: 26195859
Indian J Crit Care Med. 2015 Jun;19(6):333-9. doi: 10.4103/0972-5229.158273.

Use of antifungal agents has increased over past few decades. A number of risk factors such as immunosuppression, broad spectrum antibiotics, dialysis, pancreatitis, surgery, etc., have been linked with the increased risk of invasive candidiasis. Though there are various...

Optogenetics for retinal disorders.

Journal of ophthalmic & vision research

Henriksen BS, Marc RE, Bernstein PS.
PMID: 25667740
J Ophthalmic Vis Res. 2014 Jul-Sep;9(3):374-82. doi: 10.4103/2008-322X.143379.

Optogenetics is the use of genetic methods combined with optical technology to achieve gain or loss of function within neuronal circuits. The field of optogenetics has been rapidly expanding in efforts to restore visual function to blinding diseases such...

Perforator-based flaps for the treatment of burn scar contractures: a review.

Burns & trauma

Stekelenburg CM, Marck RE, Verhaegen PDHM, Marck KW, van Zuijlen PPM.
PMID: 28261622
Burns Trauma. 2017 Feb 27;5:5. doi: 10.1186/s41038-017-0071-2. eCollection 2017.

Patients with burn scars often experience functional problems because of scar contractures. Surgical treatment may be indicated for those burn scar contractures. If the contractures are small and linear, the contraction bands can be treated with local transposition flaps...

The ASM Curriculum Guidelines for Undergraduate Microbiology: A Case Study of the Advocacy Role of Societies in Reform Efforts.

Journal of microbiology & biology education

Horak RE, Merkel S, Chang A.
PMID: 25949769
J Microbiol Biol Educ. 2015 May 01;16(1):100-4. doi: 10.1128/jmbe.v16i1.915. eCollection 2015 May.

A number of national reports, including Vision and Change in Undergraduate Biology Education: A Call to Action, have called for drastic changes in how undergraduate biology is taught. To that end, the American Society for Microbiology (ASM) has developed...

Lipid Bilayers: The Effect of Force Field on Ordering and Dynamics.

Journal of chemical theory and computation

Poger D, Mark AE.
PMID: 26605633
J Chem Theory Comput. 2012 Nov 13;8(11):4807-17. doi: 10.1021/ct300675z. Epub 2012 Oct 18.

The sensitivity of the structure and dynamics of a fully hydrated pure bilayer of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in molecular dynamics simulations to changes in force-field and simulation parameters has been assessed. Three related force fields (the Gromos 54A7 force field,...

An Automated Force Field Topology Builder (ATB) and Repository: Version 1.0.

Journal of chemical theory and computation

Malde AK, Zuo L, Breeze M, Stroet M, Poger D, Nair PC, Oostenbrink C, Mark AE.
PMID: 26598349
J Chem Theory Comput. 2011 Dec 13;7(12):4026-37. doi: 10.1021/ct200196m. Epub 2011 Nov 15.

The Automated force field Topology Builder (ATB, http://compbio.biosci.uq.edu.au/atb ) is a Web-accessible server that can provide topologies and parameters for a wide range of molecules appropriate for use in molecular simulations, computational drug design, and X-ray refinement. The ATB...

Activating the Prolactin Receptor: Effect of the Ligand on the Conformation of the Extracellular Domain.

Journal of chemical theory and computation

Groothuizen FS, Poger D, Mark AE.
PMID: 26616789
J Chem Theory Comput. 2010 Oct 12;6(10):3274-83. doi: 10.1021/ct1003934.

The prolactin receptor resides on the surface of the cell as a preformed dimer. This suggests that cell signaling is triggered by conformational changes within the extracellular domain of the receptors. Here, by using atomistic molecular dynamics simulations, we...

Using Theory to Reconcile Experiment: The Structural and Thermodynamic Basis of Ligand Recognition by Phenylethanolamine N-Methyltransferase (PNMT).

Journal of chemical theory and computation

Nair PC, Malde AK, Mark AE.
PMID: 26610136
J Chem Theory Comput. 2011 May 10;7(5):1458-68. doi: 10.1021/ct1007229. Epub 2011 Mar 30.

A fundamental challenge in computational drug design is the availability of reliable and validated experimental binding and structural data against which theoretical calculations can be compared. In this work a combination of molecular dynamics (MD) simulations and free energy...

Quantifying adsorption-induced deformation of nanoporous materials on different length scales.

Journal of applied crystallography

Morak R, Braxmeier S, Ludescher L, Putz F, Busch S, Hüsing N, Reichenauer G, Paris O.
PMID: 29021735
J Appl Crystallogr. 2017 Sep 14;50:1404-1410. doi: 10.1107/S1600576717012274. eCollection 2017 Oct 01.

A new

ClinSeK: a targeted variant characterization framework for clinical sequencing.

Genome medicine

Zhou W, Zhao H, Chong Z, Mark RJ, Eterovic AK, Meric-Bernstam F, Chen K.
PMID: 25918555
Genome Med. 2015 Mar 31;7(1):34. doi: 10.1186/s13073-015-0155-1. eCollection 2015.

Applying genomics to patient care demands sensitive, unambiguous and rapid characterization of a known set of clinically relevant variants in patients' samples, an objective substantially different from the standard discovery process, in which every base in every sequenced read...

Mental health shared decision making in the US.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Drake RE.
PMID: 28498589
World Psychiatry. 2017 Jun;16(2):161-162. doi: 10.1002/wps.20419.

No abstract available.

Sustaining Individual Placement and Support (IPS) services: the IPS Learning Community.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Bond GR, Drake RE, Becker DR, Noel V.
PMID: 26833616
World Psychiatry. 2016 Feb;15(1):81-3. doi: 10.1002/wps.20294.

No abstract available.

Showing 1 to 12 of 257 entries