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Target Identification of .

Frontiers in pharmacology

Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP.
PMID: 29018348
Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017.

Mycobacterium phenotypic hits are a good reservoir for new chemotypes for the treatment of tuberculosis. However, the absence of defined molecular targets and modes of action could lead to failure in drug development. Therefore, a combination of ligand-based and...

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Mugumbate G, Mendes V, Blaszczyk M, et al. Target Identification of . Front Pharmacol. 2017;8:681doi: 10.3389/fphar.2017.00681.
Mugumbate, G., Mendes, V., Blaszczyk, M., Sabbah, M., Papadatos, G., Lelievre, J., Ballell, L., Barros, D., Abell, C., Blundell, T. L., & Overington, J. P. (2017). Target Identification of . Frontiers in pharmacology, 8681. https://doi.org/10.3389/fphar.2017.00681
Mugumbate, Grace, et al. "Target Identification of ." Frontiers in pharmacology vol. 8 (2017): 681. doi: https://doi.org/10.3389/fphar.2017.00681
Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP. Target Identification of . Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017. PMID: 29018348; PMCID: PMC5623190.
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Making epilepsy a national priority in African countries.

Epilepsy & behavior : E&B

Little A, Secco M, Mugumbate J.
PMID: 30414711
Epilepsy Behav. 2018 Dec;89:173-174. doi: 10.1016/j.yebeh.2018.09.024. Epub 2018 Nov 08.

No abstract available.

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Little A, Secco M, Mugumbate J. Making epilepsy a national priority in African countries. Epilepsy Behav. 2018;89:173-174doi: 10.1016/j.yebeh.2018.09.024.
Little, A., Secco, M., & Mugumbate, J. (2018). Making epilepsy a national priority in African countries. Epilepsy & behavior : E&B, 89173-174. https://doi.org/10.1016/j.yebeh.2018.09.024
Little, Ann, et al. "Making epilepsy a national priority in African countries." Epilepsy & behavior : E&B vol. 89 (2018): 173-174. doi: https://doi.org/10.1016/j.yebeh.2018.09.024
Little A, Secco M, Mugumbate J. Making epilepsy a national priority in African countries. Epilepsy Behav. 2018 Dec;89:173-174. doi: 10.1016/j.yebeh.2018.09.024. Epub 2018 Nov 08. PMID: 30414711.
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Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?.

Pharmaceuticals (Basel, Switzerland)

Moyo P, Mugumbate G, Eloff JN, Louw AI, Maharaj VJ, Birkholtz LM.
PMID: 32957668
Pharmaceuticals (Basel). 2020 Sep 17;13(9). doi: 10.3390/ph13090251.

The ability to block human-to-mosquito and mosquito-to-human transmission of

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Moyo P, Mugumbate G, Eloff JN, et al. Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?. Pharmaceuticals (Basel). 2020;13(9)doi: 10.3390/ph13090251.
Moyo, P., Mugumbate, G., Eloff, J. N., Louw, A. I., Maharaj, V. J., & Birkholtz, L. M. (2020). Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?. Pharmaceuticals (Basel, Switzerland), 13(9), . https://doi.org/10.3390/ph13090251
Moyo, Phanankosi, et al. "Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?." Pharmaceuticals (Basel, Switzerland) vol. 13,9 (2020). doi: https://doi.org/10.3390/ph13090251
Moyo P, Mugumbate G, Eloff JN, Louw AI, Maharaj VJ, Birkholtz LM. Natural Products: A Potential Source of Malaria Transmission Blocking Drugs?. Pharmaceuticals (Basel). 2020 Sep 17;13(9). doi: 10.3390/ph13090251. PMID: 32957668; PMCID: PMC7558993.
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Why does Africa have the lowest number of Neurologists and how to cover the Gap?.

Journal of the neurological sciences

Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y.
PMID: 34982975
J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29.

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to...

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Kissani N, Liqali L, Hakimi K, et al. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021;434:120119doi: 10.1016/j.jns.2021.120119.
Kissani, N., Liqali, L., Hakimi, K., Mugumbate, J., Daniel, G. M., Ibrahim, E. A. A., Yewnetu, E., Belo, M., Wilmshurst, J., Mbelesso, P., Ragab, A. H., Millogo, A., Massimo, L., & Naji, Y. (2021). Why does Africa have the lowest number of Neurologists and how to cover the Gap?. Journal of the neurological sciences, 434120119. https://doi.org/10.1016/j.jns.2021.120119
Kissani, Najib, et al. "Why does Africa have the lowest number of Neurologists and how to cover the Gap?." Journal of the neurological sciences vol. 434 (2021): 120119. doi: https://doi.org/10.1016/j.jns.2021.120119
Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29. PMID: 34982975.
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Epilepsy in Africa: Past, present, and future.

Epilepsy & behavior : E&B

Mugumbate J, Zimba AM.
PMID: 29169812
Epilepsy Behav. 2018 Feb;79:239-241. doi: 10.1016/j.yebeh.2017.10.009. Epub 2017 Nov 21.

No abstract available.

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Mugumbate J, Zimba AM. Epilepsy in Africa: Past, present, and future. Epilepsy Behav. 2017;79:239-241doi: 10.1016/j.yebeh.2017.10.009.
Mugumbate, J., & Zimba, A. M. (2018). Epilepsy in Africa: Past, present, and future. Epilepsy & behavior : E&B, 79239-241. https://doi.org/10.1016/j.yebeh.2017.10.009
Mugumbate, Jacob, and Zimba, Anthony M. "Epilepsy in Africa: Past, present, and future." Epilepsy & behavior : E&B vol. 79 (2018): 239-241. doi: https://doi.org/10.1016/j.yebeh.2017.10.009
Mugumbate J, Zimba AM. Epilepsy in Africa: Past, present, and future. Epilepsy Behav. 2018 Feb;79:239-241. doi: 10.1016/j.yebeh.2017.10.009. Epub 2017 Nov 21. PMID: 29169812.
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Why does Africa have the lowest number of Neurologists and how to cover the Gap?.

Journal of the neurological sciences

Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y.
PMID: 34982975
J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29.

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to...

Cite
Kissani N, Liqali L, Hakimi K, et al. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021;434:120119doi: 10.1016/j.jns.2021.120119.
Kissani, N., Liqali, L., Hakimi, K., Mugumbate, J., Daniel, G. M., Ibrahim, E. A. A., Yewnetu, E., Belo, M., Wilmshurst, J., Mbelesso, P., Ragab, A. H., Millogo, A., Massimo, L., & Naji, Y. (2021). Why does Africa have the lowest number of Neurologists and how to cover the Gap?. Journal of the neurological sciences, 434120119. https://doi.org/10.1016/j.jns.2021.120119
Kissani, Najib, et al. "Why does Africa have the lowest number of Neurologists and how to cover the Gap?." Journal of the neurological sciences vol. 434 (2021): 120119. doi: https://doi.org/10.1016/j.jns.2021.120119
Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29. PMID: 34982975.
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Why does Africa have the lowest number of Neurologists and how to cover the Gap?.

Journal of the neurological sciences

Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y.
PMID: 34982975
J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29.

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to...

Cite
Kissani N, Liqali L, Hakimi K, et al. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021;434:120119doi: 10.1016/j.jns.2021.120119.
Kissani, N., Liqali, L., Hakimi, K., Mugumbate, J., Daniel, G. M., Ibrahim, E. A. A., Yewnetu, E., Belo, M., Wilmshurst, J., Mbelesso, P., Ragab, A. H., Millogo, A., Massimo, L., & Naji, Y. (2021). Why does Africa have the lowest number of Neurologists and how to cover the Gap?. Journal of the neurological sciences, 434120119. https://doi.org/10.1016/j.jns.2021.120119
Kissani, Najib, et al. "Why does Africa have the lowest number of Neurologists and how to cover the Gap?." Journal of the neurological sciences vol. 434 (2021): 120119. doi: https://doi.org/10.1016/j.jns.2021.120119
Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29. PMID: 34982975.
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Why does Africa have the lowest number of Neurologists and how to cover the Gap?.

Journal of the neurological sciences

Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y.
PMID: 34982975
J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29.

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to...

Cite
Kissani N, Liqali L, Hakimi K, et al. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021;434:120119doi: 10.1016/j.jns.2021.120119.
Kissani, N., Liqali, L., Hakimi, K., Mugumbate, J., Daniel, G. M., Ibrahim, E. A. A., Yewnetu, E., Belo, M., Wilmshurst, J., Mbelesso, P., Ragab, A. H., Millogo, A., Massimo, L., & Naji, Y. (2021). Why does Africa have the lowest number of Neurologists and how to cover the Gap?. Journal of the neurological sciences, 434120119. https://doi.org/10.1016/j.jns.2021.120119
Kissani, Najib, et al. "Why does Africa have the lowest number of Neurologists and how to cover the Gap?." Journal of the neurological sciences vol. 434 (2021): 120119. doi: https://doi.org/10.1016/j.jns.2021.120119
Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29. PMID: 34982975.
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Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds.

ACS medicinal chemistry letters

Tukulula M, Njoroge M, Abay ET, Mugumbate GC, Wiesner L, Taylor D, Gibhard L, Norman J, Swart KJ, Gut J, Rosenthal PJ, Barteau S, Streckfuss J, Kameni-Tcheudji J, Chibale K.
PMID: 24900630
ACS Med Chem Lett. 2013 Oct 01;4(12):1198-202. doi: 10.1021/ml400311r. eCollection 2013 Dec 12.

A new class of 4-aminoquinolines was synthesized and evaluated in vitro for antiplasmodial activity against both the chloroquine-sensitive (3D7) and -resistant (K1 and W2) strains. The most active compounds 3c-3e had acceptable cytotoxicity but showed strong inhibition toward a...

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Tukulula M, Njoroge M, Abay ET, et al. Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds. ACS Med Chem Lett. 2013;4(12):1198-202doi: 10.1021/ml400311r.
Tukulula, M., Njoroge, M., Abay, E. T., Mugumbate, G. C., Wiesner, L., Taylor, D., Gibhard, L., Norman, J., Swart, K. J., Gut, J., Rosenthal, P. J., Barteau, S., Streckfuss, J., Kameni-Tcheudji, J., & Chibale, K. (2013). Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds. ACS medicinal chemistry letters, 4(12), 1198-202. https://doi.org/10.1021/ml400311r
Tukulula, Matshawandile, et al. "Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds." ACS medicinal chemistry letters vol. 4,12 (2013): 1198-202. doi: https://doi.org/10.1021/ml400311r
Tukulula M, Njoroge M, Abay ET, Mugumbate GC, Wiesner L, Taylor D, Gibhard L, Norman J, Swart KJ, Gut J, Rosenthal PJ, Barteau S, Streckfuss J, Kameni-Tcheudji J, Chibale K. Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds. ACS Med Chem Lett. 2013 Oct 01;4(12):1198-202. doi: 10.1021/ml400311r. eCollection 2013 Dec 12. PMID: 24900630; PMCID: PMC4027225.
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Application of Computational Methods in Understanding Mutations in .

Frontiers in molecular biosciences

Mugumbate G, Nyathi B, Zindoga A, Munyuki G.
PMID: 34651013
Front Mol Biosci. 2021 Sep 28;8:643849. doi: 10.3389/fmolb.2021.643849. eCollection 2021.

The emergence of drug-resistant strains of

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Mugumbate G, Nyathi B, Zindoga A, et al. Application of Computational Methods in Understanding Mutations in . Front Mol Biosci. 2021;8:643849doi: 10.3389/fmolb.2021.643849.
Mugumbate, G., Nyathi, B., Zindoga, A., & Munyuki, G. (2021). Application of Computational Methods in Understanding Mutations in . Frontiers in molecular biosciences, 8643849. https://doi.org/10.3389/fmolb.2021.643849
Mugumbate, Grace, et al. "Application of Computational Methods in Understanding Mutations in ." Frontiers in molecular biosciences vol. 8 (2021): 643849. doi: https://doi.org/10.3389/fmolb.2021.643849
Mugumbate G, Nyathi B, Zindoga A, Munyuki G. Application of Computational Methods in Understanding Mutations in . Front Mol Biosci. 2021 Sep 28;8:643849. doi: 10.3389/fmolb.2021.643849. eCollection 2021. PMID: 34651013; PMCID: PMC8505691.
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Why does Africa have the lowest number of Neurologists and how to cover the Gap?.

Journal of the neurological sciences

Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y.
PMID: 34982975
J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29.

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to...

Cite
Kissani N, Liqali L, Hakimi K, et al. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021;434:120119doi: 10.1016/j.jns.2021.120119.
Kissani, N., Liqali, L., Hakimi, K., Mugumbate, J., Daniel, G. M., Ibrahim, E. A. A., Yewnetu, E., Belo, M., Wilmshurst, J., Mbelesso, P., Ragab, A. H., Millogo, A., Massimo, L., & Naji, Y. (2021). Why does Africa have the lowest number of Neurologists and how to cover the Gap?. Journal of the neurological sciences, 434120119. https://doi.org/10.1016/j.jns.2021.120119
Kissani, Najib, et al. "Why does Africa have the lowest number of Neurologists and how to cover the Gap?." Journal of the neurological sciences vol. 434 (2021): 120119. doi: https://doi.org/10.1016/j.jns.2021.120119
Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29. PMID: 34982975.
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Why does Africa have the lowest number of Neurologists and how to cover the Gap?.

Journal of the neurological sciences

Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y.
PMID: 34982975
J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29.

PURPOSE: Neurology is one of Africa's central and noble specialties due to the frequency of its related diseases. Through this study we: -1-described the status of neurologists in Africa in terms of numbers,-2-listed the reasons and discussed how to...

Cite
Kissani N, Liqali L, Hakimi K, et al. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021;434:120119doi: 10.1016/j.jns.2021.120119.
Kissani, N., Liqali, L., Hakimi, K., Mugumbate, J., Daniel, G. M., Ibrahim, E. A. A., Yewnetu, E., Belo, M., Wilmshurst, J., Mbelesso, P., Ragab, A. H., Millogo, A., Massimo, L., & Naji, Y. (2021). Why does Africa have the lowest number of Neurologists and how to cover the Gap?. Journal of the neurological sciences, 434120119. https://doi.org/10.1016/j.jns.2021.120119
Kissani, Najib, et al. "Why does Africa have the lowest number of Neurologists and how to cover the Gap?." Journal of the neurological sciences vol. 434 (2021): 120119. doi: https://doi.org/10.1016/j.jns.2021.120119
Kissani N, Liqali L, Hakimi K, Mugumbate J, Daniel GM, Ibrahim EAA, Yewnetu E, Belo M, Wilmshurst J, Mbelesso P, Ragab AH, Millogo A, Massimo L, Naji Y. Why does Africa have the lowest number of Neurologists and how to cover the Gap?. J Neurol Sci. 2021 Dec 29;434:120119. doi: 10.1016/j.jns.2021.120119. Epub 2021 Dec 29. PMID: 34982975.
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Showing 1 to 12 of 12 entries