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Showing 1 to 12 of 56 entries
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Apolipoproteins and their subspecies in human cerebrospinal fluid and plasma.

Alzheimer's & dementia (Amsterdam, Netherlands)

Koch M, Furtado JD, Falk K, Leypoldt F, Mukamal KJ, Jensen MK.
PMID: 28289700
Alzheimers Dement (Amst). 2017 Feb 24;6:182-187. doi: 10.1016/j.dadm.2017.01.007. eCollection 2017.

INTRODUCTION: Subspecies of apolipoproteins can be defined by fractionating apolipoproteins based on the presence and absence of coexisting apolipoproteins.METHODS: We determined age- and sex-adjusted correlations of enzyme-linked immunosorbent assay-measured plasma and cerebrospinal fluid (CSF) apolipoproteins (apoA-I, apoC-III, apoE, and...

ACGME Duty Hour Revisions and Self-Reported Intern ICU Sleep Schedules.

Journal of graduate medical education

Allen-Dicker J, Herzig SJ, Mukamal KJ, Tess A.
PMID: 26279785
J Grad Med Educ. 2014 Sep;6(3):561-6. doi: 10.4300/JGME-D-13-00263.1.

BACKGROUND: The Accreditation Council for Graduate Medical Education duty hour standards restrict continuous duty for postgraduate year (PGY)-1 residents to 16 hours.OBJECTIVE: We aimed to assess the relationship between a duty hour-compliant schedule and resident sleep.METHODS: To comply with...

Apolipoproteins and Alzheimer's pathophysiology.

Alzheimer's & dementia (Amsterdam, Netherlands)

Koch M, DeKosky ST, Fitzpatrick AL, Furtado JD, Lopez OL, Kuller LH, Mackey RH, Hughes TM, Mukamal KJ, Jensen MK.
PMID: 30370330
Alzheimers Dement (Amst). 2018 Aug 10;10:545-553. doi: 10.1016/j.dadm.2018.07.001. eCollection 2018.

INTRODUCTION: Apolipoproteins of demonstrated importance to brain cholesterol and ß-amyloid metabolism may serve as novel risk markers for Alzheimer's pathology.METHODS: We measured apolipoproteins (apoE, apoJ, apoA-I, and apoC-III and their uniquely defined subspecies) by enzyme-linked immunosorbent assay in plasma...

Urine creatinine concentration and clinical outcomes in older adults: The Cardiovascular Health Study.

Journal of the American Geriatrics Society

Barzilay JI, Buzkova P, Shlipak MG, Lyles MF, Bansal N, Garimella PS, Ix JH, Kizer JR, Strotmeyer ES, Djousse L, Biggs ML, Siscovick D, Mukamal KJ.
PMID: 34363689
J Am Geriatr Soc. 2021 Dec;69(12):3486-3496. doi: 10.1111/jgs.17388. Epub 2021 Aug 07.

PURPOSE: Loss of muscle mass and strength are associated with long-term adverse health outcomes in older adults. Urine creatinine concentrations (Ucr; mg/dl) are a measure of muscle tissue mass and turnover. This study assessed the associations of a spot...

Associations of body size and composition with subclinical cardiac dysfunction in older individuals: the cardiovascular health study.

International journal of obesity (2005)

Garg PK, Biggs ML, Kizer JR, Shah SJ, Djousse L, Mukamal KJ.
PMID: 34349227
Int J Obes (Lond). 2021 Dec;45(12):2539-2545. doi: 10.1038/s41366-021-00926-y. Epub 2021 Aug 04.

BACKGROUND: Focused studies in younger to middle-aged populations have demonstrated a relationship between obesity and adverse cardiac mechanics. We examined whether measures of overall and central adiposity are associated with cardiac mechanics, assessed by speckle-tracking echocardiography, in an older...

Assessing short-term risk of ischemic stroke in relation to all prescribed medications.

Scientific reports

Janszky I, Vardaxis I, Lindqvist BH, Horn JW, Brumpton BM, Strand LB, Bakken IJ, Alsnes IV, Romundstad PR, Ljung R, Mukamal KJ, Sen A.
PMID: 34737336
Sci Rep. 2021 Nov 04;11(1):21673. doi: 10.1038/s41598-021-01115-7.

We examined the short-term risk of stroke associated with drugs prescribed in Norway or Sweden in a comprehensive, hypothesis-free manner using comprehensive nation-wide data. We identified 27,680 and 92,561 cases with a first ischemic stroke via the patient- and...

Serum Nonesterified Fatty Acids and Incident Stroke: The CHS.

Journal of the American Heart Association

Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH.
PMID: 34755529
J Am Heart Assoc. 2021 Nov 16;10(22):e022725. doi: 10.1161/JAHA.121.022725. Epub 2021 Nov 10.

Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies. We evaluated the associations between incident stroke and serum concentrations of nonesterified saturated, monounsaturated, polyunsaturated, and

Serum Nonesterified Fatty Acids and Incident Stroke: The CHS.

Journal of the American Heart Association

Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH.
PMID: 34755529
J Am Heart Assoc. 2021 Nov 16;10(22):e022725. doi: 10.1161/JAHA.121.022725. Epub 2021 Nov 10.

Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies. We evaluated the associations between incident stroke and serum concentrations of nonesterified saturated, monounsaturated, polyunsaturated, and

Influenza vaccination among adults with cardiovascular disease in the United States: Results from the Behavioral Risk Factor Surveillance System 2018-2019.

American heart journal

Pankayatselvan V, Mukamal KJ.
PMID: 34599883
Am Heart J. 2022 Feb;244:50-53. doi: 10.1016/j.ahj.2021.09.004. Epub 2021 Sep 29.

Influenza causes significant morbidity and mortality among adults with cardiovascular disease (CVD). In nationally representative surveys of 101,210 individuals with CVD conducted in 2018 and 2019, the self-reported rate of vaccination was only 50%, with significant disparities by race...

Plasma antioxidants and risk of dementia in older adults.

Alzheimer's & dementia (New York, N. Y.)

Koch M, Furtado JD, Cronjé HT, DeKosky ST, Fitzpatrick AL, Lopez OL, Kuller LH, Mukamal KJ, Jensen MK.
PMID: 34504943
Alzheimers Dement (N Y). 2021 Sep 05;7(1):e12208. doi: 10.1002/trc2.12208. eCollection 2021.

INTRODUCTION: Plant-based diets rich in fruits and vegetables have been associated with lower risk of dementia, but the specific role of antioxidants, a key class of bioactive phytochemicals, has not been well ascertained.METHODS: We measured antioxidants in a case-cohort...

Influenza vaccination among adults with cardiovascular disease in the United States: Results from the Behavioral Risk Factor Surveillance System 2018-2019.

American heart journal

Pankayatselvan V, Mukamal KJ.
PMID: 34599883
Am Heart J. 2021 Sep 29;244:50-53. doi: 10.1016/j.ahj.2021.09.004. Epub 2021 Sep 29.

Influenza causes significant morbidity and mortality among adults with cardiovascular disease (CVD). In nationally representative surveys of 101,210 individuals with CVD conducted in 2018 and 2019, the self-reported rate of vaccination was only 50%, with significant disparities by race...

Association of Serum Neurofilament Light Chain Concentration and MRI Findings in Older Adults: The Cardiovascular Health Study.

Neurology

Fohner AE, Bartz TM, Tracy RP, Adams HHH, Bis JC, Djousse L, Satizabal CL, Lopez OL, Seshadri S, Mukamal KJ, Kuller LH, Psaty BM, Longstreth WT.
PMID: 34921102
Neurology. 2021 Dec 17; doi: 10.1212/WNL.0000000000013229. Epub 2021 Dec 17.

BACKGROUND AND OBJECTIVES: Neurofilament light chain (NfL) in blood is a sensitive but non-specific marker of brain injury. This study sought to evaluate associations between NfL concentration and MRI findings of vascular brain injury in older adults.METHODS: A longitudinal...

Showing 1 to 12 of 56 entries