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Application of Pre-Column Labeling Liquid Chromatography for Canine Plasma-Free Amino Acid Analysis.

Metabolites

Azuma K, Hirao Y, Hayakawa Y, Murahata Y, Osaki T, Tsuka T, Imagawa T, Okamoto Y, Ito N.
PMID: 26771650
Metabolites. 2016 Jan 12;6(1). doi: 10.3390/metabo6010003.

Plasma-free amino acid (PFAA) levels are a useful metric for diagnosing cancer and providing a prognosis. However, the use of analysis of PFAA levels has been limited in the veterinary medicine field. We addressed the application of liquid chromatography...

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Azuma K, Hirao Y, Hayakawa Y, et al. Application of Pre-Column Labeling Liquid Chromatography for Canine Plasma-Free Amino Acid Analysis. Metabolites. 2016;6(1)doi: 10.3390/metabo6010003.
Azuma, K., Hirao, Y., Hayakawa, Y., Murahata, Y., Osaki, T., Tsuka, T., Imagawa, T., Okamoto, Y., & Ito, N. (2016). Application of Pre-Column Labeling Liquid Chromatography for Canine Plasma-Free Amino Acid Analysis. Metabolites, 6(1), . https://doi.org/10.3390/metabo6010003
Azuma, Kazuo, et al. "Application of Pre-Column Labeling Liquid Chromatography for Canine Plasma-Free Amino Acid Analysis." Metabolites vol. 6,1 (2016). doi: https://doi.org/10.3390/metabo6010003
Azuma K, Hirao Y, Hayakawa Y, Murahata Y, Osaki T, Tsuka T, Imagawa T, Okamoto Y, Ito N. Application of Pre-Column Labeling Liquid Chromatography for Canine Plasma-Free Amino Acid Analysis. Metabolites. 2016 Jan 12;6(1). doi: 10.3390/metabo6010003. PMID: 26771650; PMCID: PMC4812332.
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Corrigendum to "Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate" [Ultrason. Sonochem. 28 (2016) 161-168].

Ultrasonics sonochemistry

Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y.
PMID: 27291696
Ultrason Sonochem. 2017 Sep;38:751. doi: 10.1016/j.ultsonch.2016.06.002. Epub 2016 Jun 09.

No abstract available.

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Osaki T, Yokoe I, Uto Y, et al. Corrigendum to "Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate" [Ultrason. Sonochem. 28 (2016) 161-168]. Ultrason Sonochem. 2016;38:751doi: 10.1016/j.ultsonch.2016.06.002.
Osaki, T., Yokoe, I., Uto, Y., Ishizuka, M., Tanaka, T., Yamanaka, N., Kurahashi, T., Azuma, K., Murahata, Y., Tsuka, T., Ito, N., Imagawa, T., & Okamoto, Y. (2017). Corrigendum to "Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate" [Ultrason. Sonochem. 28 (2016) 161-168]. Ultrasonics sonochemistry, 38751. https://doi.org/10.1016/j.ultsonch.2016.06.002
Osaki, Tomohiro, et al. "Corrigendum to "Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate" [Ultrason. Sonochem. 28 (2016) 161-168]." Ultrasonics sonochemistry vol. 38 (2017): 751. doi: https://doi.org/10.1016/j.ultsonch.2016.06.002
Osaki T, Yokoe I, Uto Y, Ishizuka M, Tanaka T, Yamanaka N, Kurahashi T, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y. Corrigendum to "Bleomycin enhances the efficacy of sonodynamic therapy using aluminum phthalocyanine disulfonate" [Ultrason. Sonochem. 28 (2016) 161-168]. Ultrason Sonochem. 2017 Sep;38:751. doi: 10.1016/j.ultsonch.2016.06.002. Epub 2016 Jun 09. PMID: 27291696.
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Clinical systemic lupeol administration for canine oral malignant melanoma.

Molecular and clinical oncology

Yokoe I, Azuma K, Hata K, Mukaiyama T, Goto T, Tsuka T, Imagawa T, Itoh N, Murahata Y, Osaki T, Minami S, Okamoto Y.
PMID: 25469276
Mol Clin Oncol. 2015 Jan;3(1):89-92. doi: 10.3892/mco.2014.450. Epub 2014 Oct 30.

Canine oral malignant melanoma (COMM) is the most aggressive malignant tumor in dogs. Lupeol is a triterpene extracted from various fruits and vegetables that reportedly inhibits melanoma cell proliferation

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Yokoe I, Azuma K, Hata K, et al. Clinical systemic lupeol administration for canine oral malignant melanoma. Mol Clin Oncol. 2014;3(1):89-92doi: 10.3892/mco.2014.450.
Yokoe, I., Azuma, K., Hata, K., Mukaiyama, T., Goto, T., Tsuka, T., Imagawa, T., Itoh, N., Murahata, Y., Osaki, T., Minami, S., & Okamoto, Y. (2015). Clinical systemic lupeol administration for canine oral malignant melanoma. Molecular and clinical oncology, 3(1), 89-92. https://doi.org/10.3892/mco.2014.450
Yokoe, Inoru, et al. "Clinical systemic lupeol administration for canine oral malignant melanoma." Molecular and clinical oncology vol. 3,1 (2015): 89-92. doi: https://doi.org/10.3892/mco.2014.450
Yokoe I, Azuma K, Hata K, Mukaiyama T, Goto T, Tsuka T, Imagawa T, Itoh N, Murahata Y, Osaki T, Minami S, Okamoto Y. Clinical systemic lupeol administration for canine oral malignant melanoma. Mol Clin Oncol. 2015 Jan;3(1):89-92. doi: 10.3892/mco.2014.450. Epub 2014 Oct 30. PMID: 25469276; PMCID: PMC4251128.
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PI3K mutations in breast cancer: prognostic and therapeutic implications.

Breast cancer (Dove Medical Press)

Mukohara T.
PMID: 26028978
Breast Cancer (Dove Med Press). 2015 May 15;7:111-23. doi: 10.2147/BCTT.S60696. eCollection 2015.

The PI3K pathway is the most frequently enhanced oncogenic pathway in breast cancer. Among mechanisms of PI3K enhancement, PIK3CA mutations are most frequently (∼30%) observed, along with protein loss of PTEN. Since the first discovery of PIK3CA mutations in...

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Mukohara T. PI3K mutations in breast cancer: prognostic and therapeutic implications. Breast Cancer (Dove Med Press). 2015;7:111-23doi: 10.2147/BCTT.S60696.
Mukohara, T. (2015). PI3K mutations in breast cancer: prognostic and therapeutic implications. Breast cancer (Dove Medical Press), 7111-23. https://doi.org/10.2147/BCTT.S60696
Mukohara, Toru. "PI3K mutations in breast cancer: prognostic and therapeutic implications." Breast cancer (Dove Medical Press) vol. 7 (2015): 111-23. doi: https://doi.org/10.2147/BCTT.S60696
Mukohara T. PI3K mutations in breast cancer: prognostic and therapeutic implications. Breast Cancer (Dove Med Press). 2015 May 15;7:111-23. doi: 10.2147/BCTT.S60696. eCollection 2015. PMID: 26028978; PMCID: PMC4440424.
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Analysis of plasma free amino acid profiles in canine brain tumors.

Biomedical reports

Utsugi S, Azuma K, Osaki T, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y.
PMID: 28357072
Biomed Rep. 2017 Feb;6(2):195-200. doi: 10.3892/br.2016.825. Epub 2016 Dec 06.

Canine brain tumors are best diagnosed using magnetic resonance imaging (MRI). However, opportunities of MRI examination are restricted due to its limited availability in veterinary facilities; thus, numerous canine brain tumors are diagnosed at an advanced stage. Therefore, development...

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Utsugi S, Azuma K, Osaki T, et al. Analysis of plasma free amino acid profiles in canine brain tumors. Biomed Rep. 2016;6(2):195-200doi: 10.3892/br.2016.825.
Utsugi, S., Azuma, K., Osaki, T., Murahata, Y., Tsuka, T., Ito, N., Imagawa, T., & Okamoto, Y. (2017). Analysis of plasma free amino acid profiles in canine brain tumors. Biomedical reports, 6(2), 195-200. https://doi.org/10.3892/br.2016.825
Utsugi, Shinichi, et al. "Analysis of plasma free amino acid profiles in canine brain tumors." Biomedical reports vol. 6,2 (2017): 195-200. doi: https://doi.org/10.3892/br.2016.825
Utsugi S, Azuma K, Osaki T, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y. Analysis of plasma free amino acid profiles in canine brain tumors. Biomed Rep. 2017 Feb;6(2):195-200. doi: 10.3892/br.2016.825. Epub 2016 Dec 06. PMID: 28357072; PMCID: PMC5351192.
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Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer.

Chemotherapy research and practice

Mukohara T.
PMID: 22295205
Chemother Res Pract. 2011;2011:730360. doi: 10.1155/2011/730360. Epub 2011 Sep 25.

Approximately 20% of breast cancers overexpress human epidermal growth factor receptor 2 (HER2) protein, mainly as a result of gene amplification. The receptor tyrosine kinase is believed to play a critical role in the pathogenesis and further proliferation of...

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Mukohara T. Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer. Chemother Res Pract. 2011;2011:730360doi: 10.1155/2011/730360.
Mukohara, T. (2011). Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer. Chemotherapy research and practice, 2011730360. https://doi.org/10.1155/2011/730360
Mukohara, Toru. "Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer." Chemotherapy research and practice vol. 2011 (2011): 730360. doi: https://doi.org/10.1155/2011/730360
Mukohara T. Role of HER2-Targeted Agents in Adjuvant Treatment for Breast Cancer. Chemother Res Pract. 2011;2011:730360. doi: 10.1155/2011/730360. Epub 2011 Sep 25. PMID: 22295205; PMCID: PMC3263614.
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The climatic signature of incised river meanders.

Science (New York, N.Y.)

Stark CP, Barbour JR, Hayakawa YS, Hattanji T, Hovius N, Chen H, Lin CW, Horng MJ, Xu KQ, Fukahata Y.
PMID: 20299592
Science. 2010 Mar 19;327(5972):1497-501. doi: 10.1126/science.1184406.

Climate controls landscape evolution, but quantitative signatures of climatic drivers have yet to be found in topography on a broad scale. Here we describe how a topographic signature of typhoon rainfall is recorded in the meandering of incising mountain...

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Stark CP, Barbour JR, Hayakawa YS, et al. The climatic signature of incised river meanders. Science. 2010;327(5972):1497-501doi: 10.1126/science.1184406.
Stark, C. P., Barbour, J. R., Hayakawa, Y. S., Hattanji, T., Hovius, N., Chen, H., Lin, C. W., Horng, M. J., Xu, K. Q., & Fukahata, Y. (2010). The climatic signature of incised river meanders. Science (New York, N.Y.), 327(5972), 1497-501. https://doi.org/10.1126/science.1184406
Stark, Colin P, et al. "The climatic signature of incised river meanders." Science (New York, N.Y.) vol. 327,5972 (2010): 1497-501. doi: https://doi.org/10.1126/science.1184406
Stark CP, Barbour JR, Hayakawa YS, Hattanji T, Hovius N, Chen H, Lin CW, Horng MJ, Xu KQ, Fukahata Y. The climatic signature of incised river meanders. Science. 2010 Mar 19;327(5972):1497-501. doi: 10.1126/science.1184406. PMID: 20299592.
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Uterine torsion in a full-term pregnant cat.

JFMS open reports

Kuroda K, Osaki T, Harada K, Yamashita M, Murahata Y, Azuma K, Tsuka T, Ito N, Imagawa T, Okamoto Y.
PMID: 28839948
JFMS Open Rep. 2017 Aug 18;3(2):2055116917726228. doi: 10.1177/2055116917726228. eCollection 2017.

CASE SUMMARY: A 5-year-old intact female Maine Coon cat presented with a 2 day history of lethargy, anorexia and anaemia. The cat had bred 60 days previously and jumped from a height 3 days earlier, which was followed by...

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Kuroda K, Osaki T, Harada K, et al. Uterine torsion in a full-term pregnant cat. JFMS Open Rep. 2017;3(2):2055116917726228doi: 10.1177/2055116917726228.
Kuroda, K., Osaki, T., Harada, K., Yamashita, M., Murahata, Y., Azuma, K., Tsuka, T., Ito, N., Imagawa, T., & Okamoto, Y. (2017). Uterine torsion in a full-term pregnant cat. JFMS open reports, 3(2), 2055116917726228. https://doi.org/10.1177/2055116917726228
Kuroda, Kohei, et al. "Uterine torsion in a full-term pregnant cat." JFMS open reports vol. 3,2 (2017): 2055116917726228. doi: https://doi.org/10.1177/2055116917726228
Kuroda K, Osaki T, Harada K, Yamashita M, Murahata Y, Azuma K, Tsuka T, Ito N, Imagawa T, Okamoto Y. Uterine torsion in a full-term pregnant cat. JFMS Open Rep. 2017 Aug 18;3(2):2055116917726228. doi: 10.1177/2055116917726228. eCollection 2017. PMID: 28839948; PMCID: PMC5564926.
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Olecranon Apophyseal Nonunion in Adolescent Judo Players: A Report of Two Cases.

Case reports in orthopedics

Yamaura K, Mifune Y, Inui A, Nishimoto H, Ueda Y, Kataoka T, Kurosawa T, Mukohara S, Kokubu T, Kuroda R.
PMID: 30693125
Case Rep Orthop. 2018 Dec 30;2018:8256074. doi: 10.1155/2018/8256074. eCollection 2018.

Olecranon apophyseal nonunion is an elbow injury from overuse that affects adolescent athletes such as baseball pitchers who participate in overhead throwing sports. However, such injury is rare in collision sports. Here, we report two patients with this condition...

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Yamaura K, Mifune Y, Inui A, et al. Olecranon Apophyseal Nonunion in Adolescent Judo Players: A Report of Two Cases. Case Rep Orthop. 2018;2018:8256074doi: 10.1155/2018/8256074.
Yamaura, K., Mifune, Y., Inui, A., Nishimoto, H., Ueda, Y., Kataoka, T., Kurosawa, T., Mukohara, S., Kokubu, T., & Kuroda, R. (2018). Olecranon Apophyseal Nonunion in Adolescent Judo Players: A Report of Two Cases. Case reports in orthopedics, 20188256074. https://doi.org/10.1155/2018/8256074
Yamaura, Kohei, et al. "Olecranon Apophyseal Nonunion in Adolescent Judo Players: A Report of Two Cases." Case reports in orthopedics vol. 2018 (2018): 8256074. doi: https://doi.org/10.1155/2018/8256074
Yamaura K, Mifune Y, Inui A, Nishimoto H, Ueda Y, Kataoka T, Kurosawa T, Mukohara S, Kokubu T, Kuroda R. Olecranon Apophyseal Nonunion in Adolescent Judo Players: A Report of Two Cases. Case Rep Orthop. 2018 Dec 30;2018:8256074. doi: 10.1155/2018/8256074. eCollection 2018. PMID: 30693125; PMCID: PMC6332969.
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Endovascular Treatment for a Ruptured Lumbar Artery Aneurysm in a Patient with von Recklinghausen Disease.

EJVES short reports

Ishigaki T, Kawasaki R, Matsuda H, Mukohara N.
PMID: 29276786
EJVES Short Rep. 2017 Dec 06;38:1-3. doi: 10.1016/j.ejvssr.2017.11.003. eCollection 2018.

INTRODUCTION: Vasculopathy, such as an aneurysm, stenosis, rupture, or arteriovenous fistula, in patients with neurofibromatosis type I (NF-1; von Recklinghausen disease) is well recognised. However, there has been no report regarding treatment for a ruptured lumbar artery aneurysm associated...

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Ishigaki T, Kawasaki R, Matsuda H, et al. Endovascular Treatment for a Ruptured Lumbar Artery Aneurysm in a Patient with von Recklinghausen Disease. EJVES Short Rep. 2017;38:1-3doi: 10.1016/j.ejvssr.2017.11.003.
Ishigaki, T., Kawasaki, R., Matsuda, H., & Mukohara, N. (2018). Endovascular Treatment for a Ruptured Lumbar Artery Aneurysm in a Patient with von Recklinghausen Disease. EJVES short reports, 381-3. https://doi.org/10.1016/j.ejvssr.2017.11.003
Ishigaki, T, et al. "Endovascular Treatment for a Ruptured Lumbar Artery Aneurysm in a Patient with von Recklinghausen Disease." EJVES short reports vol. 38 (2018): 1-3. doi: https://doi.org/10.1016/j.ejvssr.2017.11.003
Ishigaki T, Kawasaki R, Matsuda H, Mukohara N. Endovascular Treatment for a Ruptured Lumbar Artery Aneurysm in a Patient with von Recklinghausen Disease. EJVES Short Rep. 2017 Dec 06;38:1-3. doi: 10.1016/j.ejvssr.2017.11.003. eCollection 2018. PMID: 29276786; PMCID: PMC5730433.
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Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy .

Oncology letters

Osaki T, Yokoe I, Takahashi K, Inoue K, Ishizuka M, Tanaka T, Azuma K, Murahata Y, Tsuka T, Itoh N, Imagawa T, Okamoto Y.
PMID: 28693272
Oncol Lett. 2017 Jul;14(1):1049-1053. doi: 10.3892/ol.2017.6237. Epub 2017 May 24.

The biguanide metformin is a drug widely used for the treatment of type 2 diabetes. Metformin enhances the cytotoxicity of chemotherapy by promoting the adenosine monophosphate-activated protein kinase (AMPK) autophagy signaling pathway. Photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA),...

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Osaki T, Yokoe I, Takahashi K, et al. Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy . Oncol Lett. 2017;14(1):1049-1053doi: 10.3892/ol.2017.6237.
Osaki, T., Yokoe, I., Takahashi, K., Inoue, K., Ishizuka, M., Tanaka, T., Azuma, K., Murahata, Y., Tsuka, T., Itoh, N., Imagawa, T., & Okamoto, Y. (2017). Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy . Oncology letters, 14(1), 1049-1053. https://doi.org/10.3892/ol.2017.6237
Osaki, Tomohiro, et al. "Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy ." Oncology letters vol. 14,1 (2017): 1049-1053. doi: https://doi.org/10.3892/ol.2017.6237
Osaki T, Yokoe I, Takahashi K, Inoue K, Ishizuka M, Tanaka T, Azuma K, Murahata Y, Tsuka T, Itoh N, Imagawa T, Okamoto Y. Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy . Oncol Lett. 2017 Jul;14(1):1049-1053. doi: 10.3892/ol.2017.6237. Epub 2017 May 24. PMID: 28693272; PMCID: PMC5494612.
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Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer.

Case reports in oncological medicine

Sasaki A, Harano K, Kogawa T, Matsubara N, Naito Y, Hosono A, Mukai H, Yoshino T, Mukohara T.
PMID: 32612862
Case Rep Oncol Med. 2020 Jun 16;2020:7231358. doi: 10.1155/2020/7231358. eCollection 2020.

Intestinal perforation is a rare adverse event of antineoplastic therapy. However, once it occurs, it is potentially fatal. This report describes a case of intestinal perforation caused by bevacizumab in a patient with ovarian cancer who concurrently developed neutropenic...

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Sasaki A, Harano K, Kogawa T, et al. Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer. Case Rep Oncol Med. 2020;2020:7231358doi: 10.1155/2020/7231358.
Sasaki, A., Harano, K., Kogawa, T., Matsubara, N., Naito, Y., Hosono, A., Mukai, H., Yoshino, T., & Mukohara, T. (2020). Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer. Case reports in oncological medicine, 20207231358. https://doi.org/10.1155/2020/7231358
Sasaki, Akinori, et al. "Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer." Case reports in oncological medicine vol. 2020 (2020): 7231358. doi: https://doi.org/10.1155/2020/7231358
Sasaki A, Harano K, Kogawa T, Matsubara N, Naito Y, Hosono A, Mukai H, Yoshino T, Mukohara T. Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer. Case Rep Oncol Med. 2020 Jun 16;2020:7231358. doi: 10.1155/2020/7231358. eCollection 2020. PMID: 32612862; PMCID: PMC7317333.
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Showing 1 to 12 of 68 entries