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24/7 Registered Nurse Staffing Coverage in Saskatchewan Nursing Homes and Acute Hospital Use.

Canadian journal on aging = La revue canadienne du vieillissement

McGregor MJ, Murphy JM, Poss JW, McGrail KM, Kuramoto L, Huang HC, Bryan S.
PMID: 26568323
Can J Aging. 2015 Dec;34(4):492-505. doi: 10.1017/S0714980815000434. Epub 2015 Nov 16.

RÉSUMÉ La législation, dans de nombreuses juridictions, nécessite les établissements des soins de longue durée (SLD) d'avoir une infirmière en service 24 heures par jour, 7 jours par semaine. Bien que la recherche considérable existe sur l'intensité SLD de...

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McGregor MJ, Murphy JM, Poss JW, et al. 24/7 Registered Nurse Staffing Coverage in Saskatchewan Nursing Homes and Acute Hospital Use. Can J Aging. 2015;34(4):492-505doi: 10.1017/S0714980815000434.
McGregor, M. J., Murphy, J. M., Poss, J. W., McGrail, K. M., Kuramoto, L., Huang, H. C., & Bryan, S. (2015). 24/7 Registered Nurse Staffing Coverage in Saskatchewan Nursing Homes and Acute Hospital Use. Canadian journal on aging = La revue canadienne du vieillissement, 34(4), 492-505. https://doi.org/10.1017/S0714980815000434
McGregor, Margaret J, et al. "24/7 Registered Nurse Staffing Coverage in Saskatchewan Nursing Homes and Acute Hospital Use." Canadian journal on aging = La revue canadienne du vieillissement vol. 34,4 (2015): 492-505. doi: https://doi.org/10.1017/S0714980815000434
McGregor MJ, Murphy JM, Poss JW, McGrail KM, Kuramoto L, Huang HC, Bryan S. 24/7 Registered Nurse Staffing Coverage in Saskatchewan Nursing Homes and Acute Hospital Use. Can J Aging. 2015 Dec;34(4):492-505. doi: 10.1017/S0714980815000434. Epub 2015 Nov 16. PMID: 26568323.
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Involvement of CNS cholinergic systems in alcohol drinking of P rats.

Addiction biology

Katner SN, McBRIDE WJ, Lumeng L, Li TK, Murphy JM.
PMID: 26735639
Addict Biol. 1997 Apr;2(2):215-23. doi: 10.1080/13556219772769.

Experiments were undertaken to determine if CNS muscarinic- and nicotinic-cholinergic receptors are involved in regulating alcohol drinking of rats from the selectively-bred alcohol-preferring P line. Intracerebroventricular (i.c.v.) drug infusions were administered into the lateral ventricle of female P rats...

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Katner SN, McBRIDE WJ, Lumeng L, et al. Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addict Biol. 1997;2(2):215-23doi: 10.1080/13556219772769.
Katner, S. N., McBRIDE, W. J., Lumeng, L., Li, T. K., & Murphy, J. M. (1997). Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addiction biology, 2(2), 215-23. https://doi.org/10.1080/13556219772769
Katner, S N, et al. "Involvement of CNS cholinergic systems in alcohol drinking of P rats." Addiction biology vol. 2,2 (1997): 215-23. doi: https://doi.org/10.1080/13556219772769
Katner SN, McBRIDE WJ, Lumeng L, Li TK, Murphy JM. Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addict Biol. 1997 Apr;2(2):215-23. doi: 10.1080/13556219772769. PMID: 26735639.
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Salicylic Acid Interferes with Tobacco Mosaic Virus Replication via a Novel Salicylhydroxamic Acid-Sensitive Mechanism.

The Plant cell

Chivasa S, Murphy AM, Naylor M, Carr JP.
PMID: 12237364
Plant Cell. 1997 Apr;9(4):547-557. doi: 10.1105/tpc.9.4.547.

Salicylic acid (SA) induces resistance to all plant pathogens, including bacteria, fungi, and viruses, but the mechanism by which SA engenders resistance to viruses is not known. Pretreatment of tobacco mosaic virus (TMV)-susceptible (nn genotype) tobacco tissue with SA...

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Chivasa S, Murphy AM, Naylor M, et al. Salicylic Acid Interferes with Tobacco Mosaic Virus Replication via a Novel Salicylhydroxamic Acid-Sensitive Mechanism. Plant Cell. 1997;9(4):547-557doi: 10.1105/tpc.9.4.547.
Chivasa, S., Murphy, A. M., Naylor, M., & Carr, J. P. (1997). Salicylic Acid Interferes with Tobacco Mosaic Virus Replication via a Novel Salicylhydroxamic Acid-Sensitive Mechanism. The Plant cell, 9(4), 547-557. https://doi.org/10.1105/tpc.9.4.547
Chivasa, S., et al. "Salicylic Acid Interferes with Tobacco Mosaic Virus Replication via a Novel Salicylhydroxamic Acid-Sensitive Mechanism." The Plant cell vol. 9,4 (1997): 547-557. doi: https://doi.org/10.1105/tpc.9.4.547
Chivasa S, Murphy AM, Naylor M, Carr JP. Salicylic Acid Interferes with Tobacco Mosaic Virus Replication via a Novel Salicylhydroxamic Acid-Sensitive Mechanism. Plant Cell. 1997 Apr;9(4):547-557. doi: 10.1105/tpc.9.4.547. PMID: 12237364; PMCID: PMC156938.
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Quantification of modelling uncertainties in a large ensemble of climate change simulations.

Nature

Murphy JM, Sexton DM, Barnett DN, Jones GS, Webb MJ, Collins M, Stainforth DA.
PMID: 15306806
Nature. 2004 Aug 12;430(7001):768-72. doi: 10.1038/nature02771.

Comprehensive global climate models are the only tools that account for the complex set of processes which will determine future climate change at both a global and regional level. Planners are typically faced with a wide range of predicted...

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Murphy JM, Sexton DM, Barnett DN, et al. Quantification of modelling uncertainties in a large ensemble of climate change simulations. Nature. 2004;430(7001):768-72doi: 10.1038/nature02771.
Murphy, J. M., Sexton, D. M., Barnett, D. N., Jones, G. S., Webb, M. J., Collins, M., & Stainforth, D. A. (2004). Quantification of modelling uncertainties in a large ensemble of climate change simulations. Nature, 430(7001), 768-72. https://doi.org/10.1038/nature02771
Murphy, James M, et al. "Quantification of modelling uncertainties in a large ensemble of climate change simulations." Nature vol. 430,7001 (2004): 768-72. doi: https://doi.org/10.1038/nature02771
Murphy JM, Sexton DM, Barnett DN, Jones GS, Webb MJ, Collins M, Stainforth DA. Quantification of modelling uncertainties in a large ensemble of climate change simulations. Nature. 2004 Aug 12;430(7001):768-72. doi: 10.1038/nature02771. PMID: 15306806.
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C-H activation for the construction of C-B bonds.

Chemical reviews

Mkhalid IA, Barnard JH, Marder TB, Murphy JM, Hartwig JF.
PMID: 20028025
Chem Rev. 2010 Feb 10;110(2):890-931. doi: 10.1021/cr900206p.

No abstract available.

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Mkhalid IA, Barnard JH, Marder TB, et al. C-H activation for the construction of C-B bonds. Chem Rev. 2010;110(2):890-931doi: 10.1021/cr900206p.
Mkhalid, I. A., Barnard, J. H., Marder, T. B., Murphy, J. M., & Hartwig, J. F. (2010). C-H activation for the construction of C-B bonds. Chemical reviews, 110(2), 890-931. https://doi.org/10.1021/cr900206p
Mkhalid, Ibraheem A I, et al. "C-H activation for the construction of C-B bonds." Chemical reviews vol. 110,2 (2010): 890-931. doi: https://doi.org/10.1021/cr900206p
Mkhalid IA, Barnard JH, Marder TB, Murphy JM, Hartwig JF. C-H activation for the construction of C-B bonds. Chem Rev. 2010 Feb 10;110(2):890-931. doi: 10.1021/cr900206p. PMID: 20028025.
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Screening for psychosocial dysfunction in economically disadvantaged and minority group children: further validation of the Pediatric Symptom Checklist.

The American journal of orthopsychiatry

Murphy JM, Jellinek M.
PMID: 3407735
Am J Orthopsychiatry. 1988 Jul;58(3):450-456. doi: 10.1111/j.1939-0025.1988.tb01605.x.

This study assessed the validity and reliability of the Pediatric Symptom Checklist (PSC) for screening lower-middle-class and minority group children. PSCs were collected from parents of 300 pediatric outpatients aged six to 12 years and 48 of these children...

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Murphy JM, Jellinek M. Screening for psychosocial dysfunction in economically disadvantaged and minority group children: further validation of the Pediatric Symptom Checklist. Am J Orthopsychiatry. 1988;58(3):450-456doi: 10.1111/j.1939-0025.1988.tb01605.x.
Murphy, J. M., & Jellinek, M. (1988). Screening for psychosocial dysfunction in economically disadvantaged and minority group children: further validation of the Pediatric Symptom Checklist. The American journal of orthopsychiatry, 58(3), 450-456. https://doi.org/10.1111/j.1939-0025.1988.tb01605.x
Murphy, J Michael, and Jellinek, Michael. "Screening for psychosocial dysfunction in economically disadvantaged and minority group children: further validation of the Pediatric Symptom Checklist." The American journal of orthopsychiatry vol. 58,3 (1988): 450-456. doi: https://doi.org/10.1111/j.1939-0025.1988.tb01605.x
Murphy JM, Jellinek M. Screening for psychosocial dysfunction in economically disadvantaged and minority group children: further validation of the Pediatric Symptom Checklist. Am J Orthopsychiatry. 1988 Jul;58(3):450-456. doi: 10.1111/j.1939-0025.1988.tb01605.x. PMID: 3407735.
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Advancing national climate change risk assessment to deliver national adaptation plans.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Warren RF, Wilby RL, Brown K, Watkiss P, Betts RA, Murphy JM, Lowe JA.
PMID: 29712791
Philos Trans A Math Phys Eng Sci. 2018 Jun 13;376(2121). doi: 10.1098/rsta.2017.0295.

A wide range of climate vulnerability and risk assessments have been implemented using different approaches at different scales, some with a broad multi-sectoral scope and others focused on single risks or sectors. This paper describes the novel approach to...

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Warren RF, Wilby RL, Brown K, et al. Advancing national climate change risk assessment to deliver national adaptation plans. Philos Trans A Math Phys Eng Sci. 2018;376(2121)doi: 10.1098/rsta.2017.0295.
Warren, R. F., Wilby, R. L., Brown, K., Watkiss, P., Betts, R. A., Murphy, J. M., & Lowe, J. A. (2018). Advancing national climate change risk assessment to deliver national adaptation plans. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 376(2121), . https://doi.org/10.1098/rsta.2017.0295
Warren, R F, et al. "Advancing national climate change risk assessment to deliver national adaptation plans." Philosophical transactions. Series A, Mathematical, physical, and engineering sciences vol. 376,2121 (2018). doi: https://doi.org/10.1098/rsta.2017.0295
Warren RF, Wilby RL, Brown K, Watkiss P, Betts RA, Murphy JM, Lowe JA. Advancing national climate change risk assessment to deliver national adaptation plans. Philos Trans A Math Phys Eng Sci. 2018 Jun 13;376(2121). doi: 10.1098/rsta.2017.0295. PMID: 29712791; PMCID: PMC5938631.
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Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome.

Frontiers in bioengineering and biotechnology

Mancuso P, Raman S, Glynn A, Barry F, Murphy JM.
PMID: 30761298
Front Bioeng Biotechnol. 2019 Jan 29;7:9. doi: 10.3389/fbioe.2019.00009. eCollection 2019.

Osteoarthritis (OA) is an inflammatory condition still lacking effective treatments. Mesenchymal stem/stromal cells (MSCs) have been successfully employed in pre-clinical models aiming to resurface the degenerated cartilage. In early-phase clinical trials, intra-articular (IA) administration of MSCs leads to pain...

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Mancuso P, Raman S, Glynn A, et al. Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome. Front Bioeng Biotechnol. 2019;7:9doi: 10.3389/fbioe.2019.00009.
Mancuso, P., Raman, S., Glynn, A., Barry, F., & Murphy, J. M. (2019). Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome. Frontiers in bioengineering and biotechnology, 79. https://doi.org/10.3389/fbioe.2019.00009
Mancuso, Patrizio, et al. "Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome." Frontiers in bioengineering and biotechnology vol. 7 (2019): 9. doi: https://doi.org/10.3389/fbioe.2019.00009
Mancuso P, Raman S, Glynn A, Barry F, Murphy JM. Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome. Front Bioeng Biotechnol. 2019 Jan 29;7:9. doi: 10.3389/fbioe.2019.00009. eCollection 2019. PMID: 30761298; PMCID: PMC6361779.
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Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis.

Frontiers in bioengineering and biotechnology

Raman S, FitzGerald U, Murphy JM.
PMID: 29594113
Front Bioeng Biotechnol. 2018 Mar 14;6:22. doi: 10.3389/fbioe.2018.00022. eCollection 2018.

Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary diseases thought to be major factors driving the process of articular cartilage degeneration. Chondrocytes, the cellular component...

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Raman S, FitzGerald U, Murphy JM. Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis. Front Bioeng Biotechnol. 2018;6:22doi: 10.3389/fbioe.2018.00022.
Raman, S., FitzGerald, U., & Murphy, J. M. (2018). Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis. Frontiers in bioengineering and biotechnology, 622. https://doi.org/10.3389/fbioe.2018.00022
Raman, Swarna, et al. "Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis." Frontiers in bioengineering and biotechnology vol. 6 (2018): 22. doi: https://doi.org/10.3389/fbioe.2018.00022
Raman S, FitzGerald U, Murphy JM. Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis. Front Bioeng Biotechnol. 2018 Mar 14;6:22. doi: 10.3389/fbioe.2018.00022. eCollection 2018. PMID: 29594113; PMCID: PMC5861204.
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Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening.

Chemical science

Narayanam MK, Liang Y, Houk KN, Murphy JM.
PMID: 29910881
Chem Sci. 2016 Feb 01;7(2):1257-1261. doi: 10.1039/c5sc03259h. Epub 2015 Nov 11.

Density functional theory (DFT) calculations and experiments in tandem led to discoveries of new reactivities and selectivities involving bioorthogonal sydnone cycloadditions. Dibenzocyclooctyne derivatives (DIBAC and BARAC) were identified to be especially reactive dipolarophiles, which undergo the (3 + 2)...

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Narayanam MK, Liang Y, Houk KN, et al. Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. Chem Sci. 2015;7(2):1257-1261doi: 10.1039/c5sc03259h.
Narayanam, M. K., Liang, Y., Houk, K. N., & Murphy, J. M. (2016). Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. Chemical science, 7(2), 1257-1261. https://doi.org/10.1039/c5sc03259h
Narayanam, Maruthi Kumar, et al. "Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening." Chemical science vol. 7,2 (2016): 1257-1261. doi: https://doi.org/10.1039/c5sc03259h
Narayanam MK, Liang Y, Houk KN, Murphy JM. Discovery of new mutually orthogonal bioorthogonal cycloaddition pairs through computational screening. Chem Sci. 2016 Feb 01;7(2):1257-1261. doi: 10.1039/c5sc03259h. Epub 2015 Nov 11. PMID: 29910881; PMCID: PMC4763938.
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Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy.

The Journal of biological chemistry

Choi CS, Gwin M, Voth S, Kolb C, Zhou C, Nelson AR, deWeever A, Koloteva A, Annamdevula NS, Murphy JM, Wagener BM, Pittet JF, Lim SS, Balczon R, Stevens T, Lin MT.
PMID: 34896150
J Biol Chem. 2021 Dec 08;298(1):101482. doi: 10.1016/j.jbc.2021.101482. Epub 2021 Dec 08.

Patients who recover from nosocomial pneumonia oftentimes exhibit long-lasting cognitive impairment comparable with what is observed in Alzheimer's disease patients. We previously hypothesized that the lung endothelium contributes to infection-related neurocognitive dysfunction, because bacteria-exposed endothelial cells release a form(s)...

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Choi CS, Gwin M, Voth S, et al. Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy. J Biol Chem. 2021;298(1):101482doi: 10.1016/j.jbc.2021.101482.
Choi, C. S., Gwin, M., Voth, S., Kolb, C., Zhou, C., Nelson, A. R., deWeever, A., Koloteva, A., Annamdevula, N. S., Murphy, J. M., Wagener, B. M., Pittet, J. F., Lim, S. S., Balczon, R., Stevens, T., & Lin, M. T. (2021). Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy. The Journal of biological chemistry, 298(1), 101482. https://doi.org/10.1016/j.jbc.2021.101482
Choi, Chung-Sik, et al. "Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy." The Journal of biological chemistry vol. 298,1 (2021): 101482. doi: https://doi.org/10.1016/j.jbc.2021.101482
Choi CS, Gwin M, Voth S, Kolb C, Zhou C, Nelson AR, deWeever A, Koloteva A, Annamdevula NS, Murphy JM, Wagener BM, Pittet JF, Lim SS, Balczon R, Stevens T, Lin MT. Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy. J Biol Chem. 2021 Dec 08;298(1):101482. doi: 10.1016/j.jbc.2021.101482. Epub 2021 Dec 08. PMID: 34896150.
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Phosphorylation by Aurora B kinase regulates caspase-2 activity and function.

Cell death and differentiation

Lim Y, De Bellis D, Sandow JJ, Capalbo L, D'Avino PP, Murphy JM, Webb AI, Dorstyn L, Kumar S.
PMID: 32811973
Cell Death Differ. 2021 Jan;28(1):349-366. doi: 10.1038/s41418-020-00604-y. Epub 2020 Aug 18.

Mitotic catastrophe (MC) is an important oncosuppressive mechanism that serves to eliminate cells that become polyploid or aneuploid due to aberrant mitosis. Previous studies have demonstrated that the activation and catalytic function of caspase-2 are key steps in MC...

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Lim Y, De Bellis D, Sandow JJ, et al. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function. Cell Death Differ. 2020;28(1):349-366doi: 10.1038/s41418-020-00604-y.
Lim, Y., De Bellis, D., Sandow, J. J., Capalbo, L., D'Avino, P. P., Murphy, J. M., Webb, A. I., Dorstyn, L., & Kumar, S. (2021). Phosphorylation by Aurora B kinase regulates caspase-2 activity and function. Cell death and differentiation, 28(1), 349-366. https://doi.org/10.1038/s41418-020-00604-y
Lim, Yoon, et al. "Phosphorylation by Aurora B kinase regulates caspase-2 activity and function." Cell death and differentiation vol. 28,1 (2021): 349-366. doi: https://doi.org/10.1038/s41418-020-00604-y
Lim Y, De Bellis D, Sandow JJ, Capalbo L, D'Avino PP, Murphy JM, Webb AI, Dorstyn L, Kumar S. Phosphorylation by Aurora B kinase regulates caspase-2 activity and function. Cell Death Differ. 2021 Jan;28(1):349-366. doi: 10.1038/s41418-020-00604-y. Epub 2020 Aug 18. PMID: 32811973; PMCID: PMC7852673.
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Showing 1 to 12 of 90 entries