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The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection.

Oncotarget

Muscat AM, Wong NC, Drummond KJ, Algar EM, Khasraw M, Verhaak R, Field K, Rosenthal MA, Ashley DM.
PMID: 29487696
Oncotarget. 2017 Dec 15;9(8):7844-7858. doi: 10.18632/oncotarget.23541. eCollection 2018 Jan 30.

Glioblastoma presents as a heterogeneous disease with poor prognosis despite the use of multimodal therapy. Analysis of genomic DNA changes between initial diagnosis and recurrence in response to standard treatment protocols would enhance understanding of disease progression and better...

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Muscat AM, Wong NC, Drummond KJ, et al. The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection. Oncotarget. 2017;9(8):7844-7858doi: 10.18632/oncotarget.23541.
Muscat, A. M., Wong, N. C., Drummond, K. J., Algar, E. M., Khasraw, M., Verhaak, R., Field, K., Rosenthal, M. A., & Ashley, D. M. (2018). The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection. Oncotarget, 9(8), 7844-7858. https://doi.org/10.18632/oncotarget.23541
Muscat, Andrea M, et al. "The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection." Oncotarget vol. 9,8 (2018): 7844-7858. doi: https://doi.org/10.18632/oncotarget.23541
Muscat AM, Wong NC, Drummond KJ, Algar EM, Khasraw M, Verhaak R, Field K, Rosenthal MA, Ashley DM. The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection. Oncotarget. 2017 Dec 15;9(8):7844-7858. doi: 10.18632/oncotarget.23541. eCollection 2018 Jan 30. PMID: 29487696; PMCID: PMC5814263.
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Ammonia photodissociation promoted by Si(100).

The journal of physical chemistry. A

Finstad CC, Muscat AJ.
PMID: 24802663
J Phys Chem A. 2014 Jun 05;118(22):3880-90. doi: 10.1021/jp408543e. Epub 2014 May 20.

Using in situ X-ray photoelectron spectroscopy measurements after reaction, we show that hydrogen-terminated Si(100) perturbs the bonding of physisorbed NH3 enabling a photochemical decomposition pathway at wavelengths different from those characteristic of either the molecule in the gas phase...

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Finstad CC, Muscat AJ. Ammonia photodissociation promoted by Si(100). J Phys Chem A. 2014;118(22):3880-90doi: 10.1021/jp408543e.
Finstad, C. C., & Muscat, A. J. (2014). Ammonia photodissociation promoted by Si(100). The journal of physical chemistry. A, 118(22), 3880-90. https://doi.org/10.1021/jp408543e
Finstad, Casey C, and Muscat, Anthony J. "Ammonia photodissociation promoted by Si(100)." The journal of physical chemistry. A vol. 118,22 (2014): 3880-90. doi: https://doi.org/10.1021/jp408543e
Finstad CC, Muscat AJ. Ammonia photodissociation promoted by Si(100). J Phys Chem A. 2014 Jun 05;118(22):3880-90. doi: 10.1021/jp408543e. Epub 2014 May 20. PMID: 24802663.
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Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks.

Cancers

Jones NR, Ashmore JH, Lee SY, Richie JP, Lazarus P, Muscat JE.
PMID: 26690219
Cancers (Basel). 2015 Dec 09;7(4):2386-96. doi: 10.3390/cancers7040898.

BACKGROUND: Polymorphisms in the hemochromatosis (HFE) gene are associated with excessive iron absorption from the diet, and pro-oxidant effects of iron accumulation are thought to be a risk factor for several types of cancer.METHODS: The C282Y (rs1800562) and H63D...

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Jones NR, Ashmore JH, Lee SY, et al. Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks. Cancers (Basel). 2015;7(4):2386-96doi: 10.3390/cancers7040898.
Jones, N. R., Ashmore, J. H., Lee, S. Y., Richie, J. P., Lazarus, P., & Muscat, J. E. (2015). Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks. Cancers, 7(4), 2386-96. https://doi.org/10.3390/cancers7040898
Jones, Nathan R, et al. "Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks." Cancers vol. 7,4 (2015): 2386-96. doi: https://doi.org/10.3390/cancers7040898
Jones NR, Ashmore JH, Lee SY, Richie JP, Lazarus P, Muscat JE. Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks. Cancers (Basel). 2015 Dec 09;7(4):2386-96. doi: 10.3390/cancers7040898. PMID: 26690219; PMCID: PMC4695898.
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Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study.

Behavioural pharmacology

Muscat R, Patel J, Trout SJ, Wieczorek W, Kruk ZL.
PMID: 11224210
Behav Pharmacol. 1993;4(4):411-418.

Behavioural sensitization to the locomotor stimulant effect of (+)-amphetamine or quinpirole was induced in rats by intermittent drug administration. Once established, endogenous dopamine release (DA) was measured in slices containing nucleus accumbens using fast cyclic voltammetry. DA release induced...

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Muscat R, Patel J, Trout SJ, et al. Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study. Behav Pharmacol. 1993;4(4):411-418
Muscat, R., Patel, J., Trout, S. J., Wieczorek, W., & Kruk, Z. L. (1993). Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study. Behavioural pharmacology, 4(4), 411-418.
Muscat, R., et al. "Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study." Behavioural pharmacology vol. 4,4 (1993): 411-418.
Muscat R, Patel J, Trout SJ, Wieczorek W, Kruk ZL. Dissociation of the effects of amphetamine and quinpirole on dopamine release in the nucleus accumbens following behavioural sensitization: an ex vivo voltammetric study. Behav Pharmacol. 1993;4(4):411-418. PMID: 11224210.
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Time-dependent and schedule-dependent effects of dopamine receptor blockade.

Behavioural pharmacology

Willner P, Phillips G, Sampson D, Muscat R.
PMID: 11175400
Behav Pharmacol. 1989;1(2):169-176.

Rats were trained on one of two multiple random-interval schedules of reinforcement, which contained both ascending and descending reinforcement density sequences. The design of the schedules made it possible to determine whether performance changes in a particular component depended...

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Willner P, Phillips G, Sampson D, et al. Time-dependent and schedule-dependent effects of dopamine receptor blockade. Behav Pharmacol. 1989;1(2):169-176
Willner, P., Phillips, G., Sampson, D., & Muscat, R. (1989). Time-dependent and schedule-dependent effects of dopamine receptor blockade. Behavioural pharmacology, 1(2), 169-176.
Willner, P., et al. "Time-dependent and schedule-dependent effects of dopamine receptor blockade." Behavioural pharmacology vol. 1,2 (1989): 169-176.
Willner P, Phillips G, Sampson D, Muscat R. Time-dependent and schedule-dependent effects of dopamine receptor blockade. Behav Pharmacol. 1989;1(2):169-176. PMID: 11175400.
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The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?.

Nuclear receptor signaling

Ramakrishnan SN, Muscat GE.
PMID: 16741567
Nucl Recept Signal. 2006;4:e009. doi: 10.1621/nrs.04009. Epub 2006 Apr 28.

Nuclear hormone receptors (NRs) function as ligand dependent DNA binding proteins that translate physiological/nutritional signals into gene regulation. Dysfunctional NR signaling leads to many disorders in reproduction, inflammation, and metabolism. The opportunity to identify novel regulatory pathways in the...

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Ramakrishnan SN, Muscat GE. The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?. Nucl Recept Signal. 2006;4:e009doi: 10.1621/nrs.04009.
Ramakrishnan, S. N., & Muscat, G. E. (2006). The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?. Nuclear receptor signaling, 4e009. https://doi.org/10.1621/nrs.04009
Ramakrishnan, Sathiya N, and Muscat, George E O. "The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?." Nuclear receptor signaling vol. 4 (2006): e009. doi: https://doi.org/10.1621/nrs.04009
Ramakrishnan SN, Muscat GE. The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?. Nucl Recept Signal. 2006;4:e009. doi: 10.1621/nrs.04009. Epub 2006 Apr 28. PMID: 16741567; PMCID: PMC1472670.
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Capillary affinity gel electrophoresis for combined size- and sequence-dependent separation of oligonucleotides.

Analytical chemistry

Muscate A, Natt F, Paulus A, Ehrat M.
PMID: 21644736
Anal Chem. 1998 Apr 01;70(7):1419-24. doi: 10.1021/ac971057f.

An interesting new approach to capillary affinity gel electrophoresis (CAGE) has been developed for the selective capture and separation of homopolymer and heteropolymer oligonucleotides. The combination of selectivity of bioaffinity recognition and high-resolution power of capillary gel electrophoresis allows...

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Muscate A, Natt F, Paulus A, et al. Capillary affinity gel electrophoresis for combined size- and sequence-dependent separation of oligonucleotides. Anal Chem. 1998;70(7):1419-24doi: 10.1021/ac971057f.
Muscate, A., Natt, F., Paulus, A., & Ehrat, M. (1998). Capillary affinity gel electrophoresis for combined size- and sequence-dependent separation of oligonucleotides. Analytical chemistry, 70(7), 1419-24. https://doi.org/10.1021/ac971057f
Muscate, A, et al. "Capillary affinity gel electrophoresis for combined size- and sequence-dependent separation of oligonucleotides." Analytical chemistry vol. 70,7 (1998): 1419-24. doi: https://doi.org/10.1021/ac971057f
Muscate A, Natt F, Paulus A, Ehrat M. Capillary affinity gel electrophoresis for combined size- and sequence-dependent separation of oligonucleotides. Anal Chem. 1998 Apr 01;70(7):1419-24. doi: 10.1021/ac971057f. PMID: 21644736.
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[Prophylactic cranial irradiation in patients with extensive disease caused by small-cell lung cancer responsive to chemotherapy: fewer symptomatic brain metastases and improved survival].

Nederlands tijdschrift voor geneeskunde

Slotman BJ, Faivre-Finn C, Kramer GW, Rankin E, Snee M, Hatton M, Postmus PE, Collette L, Musat E, Senan S.
PMID: 18549175
Ned Tijdschr Geneeskd. 2008 Apr 26;152(17):1000-4.

OBJECTIVE: To determine the effect of prophylactic cranial irradiation (PCI) in patients with extensive-disease small-cell lung cancer (ED-SCLC) who responded to chemotherapy.DESIGN: Randomised, controlled clinical trial; phase III study (EORTC nr 08993-22993; www.clinicaltrials.gov, nr NCT00016211).METHOD: Patients aged 18-75 years...

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Slotman BJ, Faivre-Finn C, Kramer GW, et al. Profylactische schedelbestraling bij patiënten met uitgebreid kleincellig longcarcinoom dat reageert op chemotherapie: minder symptomatische hersenmetastasen en betere overleving. [Prophylactic cranial irradiation in patients with extensive disease caused by small-cell lung cancer responsive to chemotherapy: fewer symptomatic brain metastases and improved survival]. Ned Tijdschr Geneeskd. 2008;152(17):1000-4
Slotman, B. J., Faivre-Finn, C., Kramer, G. W., Rankin, E., Snee, M., Hatton, M., Postmus, P. E., Collette, L., Musat, E., & Senan, S. (2008). Profylactische schedelbestraling bij patiënten met uitgebreid kleincellig longcarcinoom dat reageert op chemotherapie: minder symptomatische hersenmetastasen en betere overleving. [Prophylactic cranial irradiation in patients with extensive disease caused by small-cell lung cancer responsive to chemotherapy: fewer symptomatic brain metastases and improved survival]. Nederlands tijdschrift voor geneeskunde, 152(17), 1000-4.
Slotman, B J, et al. "Profylactische schedelbestraling bij patiënten met uitgebreid kleincellig longcarcinoom dat reageert op chemotherapie: minder symptomatische hersenmetastasen en betere overleving." [Prophylactic cranial irradiation in patients with extensive disease caused by small-cell lung cancer responsive to chemotherapy: fewer symptomatic brain metastases and improved survival]. Nederlands tijdschrift voor geneeskunde vol. 152,17 (2008): 1000-4.
Slotman BJ, Faivre-Finn C, Kramer GW, Rankin E, Snee M, Hatton M, Postmus PE, Collette L, Musat E, Senan S. Profylactische schedelbestraling bij patiënten met uitgebreid kleincellig longcarcinoom dat reageert op chemotherapie: minder symptomatische hersenmetastasen en betere overleving. [Prophylactic cranial irradiation in patients with extensive disease caused by small-cell lung cancer responsive to chemotherapy: fewer symptomatic brain metastases and improved survival]. Ned Tijdschr Geneeskd. 2008 Apr 26;152(17):1000-4. Dutch. PMID: 18549175.
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Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer.

Journal of contemporary brachytherapy

Palmer A, Hayman O, Muscat S.
PMID: 23346140
J Contemp Brachytherapy. 2012 Mar;4(1):52-9. doi: 10.5114/jcb.2012.27952. Epub 2012 Mar 30.

PURPOSE: To evaluate whether Co-60 is equivalent to Ir-192 for HDR cervical brachytherapy, through 3D-DVH dose comparisons in standard and optimised plans. Previous studies have only considered 2D dosimetry, point dose comparisons or identical loading. Typical treatment times and...

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Palmer A, Hayman O, Muscat S. Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer. J Contemp Brachytherapy. 2012;4(1):52-9doi: 10.5114/jcb.2012.27952.
Palmer, A., Hayman, O., & Muscat, S. (2012). Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer. Journal of contemporary brachytherapy, 4(1), 52-9. https://doi.org/10.5114/jcb.2012.27952
Palmer, Antony, et al. "Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer." Journal of contemporary brachytherapy vol. 4,1 (2012): 52-9. doi: https://doi.org/10.5114/jcb.2012.27952
Palmer A, Hayman O, Muscat S. Treatment planning study of the 3D dosimetric differences between Co-60 and Ir-192 sources in high dose rate (HDR) brachytherapy for cervix cancer. J Contemp Brachytherapy. 2012 Mar;4(1):52-9. doi: 10.5114/jcb.2012.27952. Epub 2012 Mar 30. PMID: 23346140; PMCID: PMC3551368.
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P53 protein overexpression in lung adenocarcinomas in non-smokers.

Oncology reports

Muscat J, Citron M, Wang C, White A, Lazarus P.
PMID: 21590150
Oncol Rep. 1997 Jul-Aug;4(4):825-7. doi: 10.3892/or.4.4.825.

Greater than 55% of all lung cancers contain mutations in the p53 tumor suppressor gene, and the frequency of p53 mutations has been directly correlated with the use of tobacco and the smoking of cigarettes. To determine if environmental...

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Muscat J, Citron M, Wang C, et al. P53 protein overexpression in lung adenocarcinomas in non-smokers. Oncol Rep. 1997;4(4):825-7doi: 10.3892/or.4.4.825.
Muscat, J., Citron, M., Wang, C., White, A., & Lazarus, P. (1997). P53 protein overexpression in lung adenocarcinomas in non-smokers. Oncology reports, 4(4), 825-7. https://doi.org/10.3892/or.4.4.825
Muscat, J, et al. "P53 protein overexpression in lung adenocarcinomas in non-smokers." Oncology reports vol. 4,4 (1997): 825-7. doi: https://doi.org/10.3892/or.4.4.825
Muscat J, Citron M, Wang C, White A, Lazarus P. P53 protein overexpression in lung adenocarcinomas in non-smokers. Oncol Rep. 1997 Jul-Aug;4(4):825-7. doi: 10.3892/or.4.4.825. PMID: 21590150.
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Effects of amphetamine and pimozide on reinforcement and motor parameters in variable-interval performance.

Journal of psychopharmacology (Oxford, England)

Willner P, Towell A, Muscat R.
PMID: 22158977
J Psychopharmacol. 1987 Jan;1(3):140-53. doi: 10.1177/026988118700100302.

The effects of amphetamine and pimozide were studied in rats performing on variable-interval (VI) schedules of reinforcement. In experiment 1, a five-component multiple VI schedule was used; in experiments 2 and 3, two VI schedules were presented on alternate...

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Willner P, Towell A, Muscat R. Effects of amphetamine and pimozide on reinforcement and motor parameters in variable-interval performance. J Psychopharmacol. 1987;1(3):140-53doi: 10.1177/026988118700100302.
Willner, P., Towell, A., & Muscat, R. (1987). Effects of amphetamine and pimozide on reinforcement and motor parameters in variable-interval performance. Journal of psychopharmacology (Oxford, England), 1(3), 140-53. https://doi.org/10.1177/026988118700100302
Willner, P, et al. "Effects of amphetamine and pimozide on reinforcement and motor parameters in variable-interval performance." Journal of psychopharmacology (Oxford, England) vol. 1,3 (1987): 140-53. doi: https://doi.org/10.1177/026988118700100302
Willner P, Towell A, Muscat R. Effects of amphetamine and pimozide on reinforcement and motor parameters in variable-interval performance. J Psychopharmacol. 1987 Jan;1(3):140-53. doi: 10.1177/026988118700100302. PMID: 22158977.
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Knowing You, Knowing Me (KYKM): an interactive game to address positive mother-daughter communication and relationships.

Frontiers in psychology

Katsikitis M, Jones C, Muscat M, Crawford K.
PMID: 25071682
Front Psychol. 2014 Jul 11;5:721. doi: 10.3389/fpsyg.2014.00721. eCollection 2014.

This technical report describes an interactive game environment designed to bring mothers and their adolescent daughters together to discuss three issues that have previously been shown in the literature to be of concern to families, as young girls transition...

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Katsikitis M, Jones C, Muscat M, et al. Knowing You, Knowing Me (KYKM): an interactive game to address positive mother-daughter communication and relationships. Front Psychol. 2014;5:721doi: 10.3389/fpsyg.2014.00721.
Katsikitis, M., Jones, C., Muscat, M., & Crawford, K. (2014). Knowing You, Knowing Me (KYKM): an interactive game to address positive mother-daughter communication and relationships. Frontiers in psychology, 5721. https://doi.org/10.3389/fpsyg.2014.00721
Katsikitis, Mary, et al. "Knowing You, Knowing Me (KYKM): an interactive game to address positive mother-daughter communication and relationships." Frontiers in psychology vol. 5 (2014): 721. doi: https://doi.org/10.3389/fpsyg.2014.00721
Katsikitis M, Jones C, Muscat M, Crawford K. Knowing You, Knowing Me (KYKM): an interactive game to address positive mother-daughter communication and relationships. Front Psychol. 2014 Jul 11;5:721. doi: 10.3389/fpsyg.2014.00721. eCollection 2014. PMID: 25071682; PMCID: PMC4093658.
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Showing 1 to 12 of 176 entries