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Data on microcirculatory parameters of GTS- 21 treated rats assessed by intravital microscopy.

Data in brief

Schmidt K, Bhakdisongkhram S, Uhle F, Philipsenburg C, Zivkovic AR, Brenner T, Motsch J, Weigand MA, Hofer S.
PMID: 29022002
Data Brief. 2017 Sep 23;15:228-233. doi: 10.1016/j.dib.2017.09.045. eCollection 2017 Dec.

This article contains animal experimental data associated with the research article entitled "GTS-21 reduces microvascular permeability during experimental endotoxemia" (Schmidt et al., 2017) [1] (supplementary datasets of baseline intravital microscopic measurements, baseline TNF-α levels and vital parameters of the...

Moderate intensity physical activity prevents increased blood glucose concentrations, fat pad deposition and cardiac action potential prolongation following diet-induced obesity in a juvenile-adolescent rat model.

BMC obesity

van Waveren A, Duncan MJ, Coulson FR, Fenning A.
PMID: 26217503
BMC Obes. 2014 Aug 20;1:11. doi: 10.1186/2052-9538-1-11. eCollection 2014.

BACKGROUND: Both obesity and a lack of physical activity have been associated with an elevated risk of cardiovascular disease (CVD). The incidence of obesity is increasing, especially in juvenile-adolescents. While there is limited research examining the chronic effects of...

Advances in the treatment of pediatric obsessive-compulsive d-cycloserine with exposure and response prevention.

Neuropsychiatry

McGuire JF, Lewin AB, Geller DA, Brown A, Ramsey K, Mutch J, Mittelman A, Micco J, Jordan C, Wilhelm S, Murphy TK, Small BJ, Storch EA.
PMID: 24174993
Neuropsychiatry (London). 2012 Aug;2(4). doi: 10.2217/npy.12.38.

Exposure-based cognitive-behavioral therapy and serotonin reuptake inhibitor medications are efficacious treatment options for the management of pediatric obsessive-compulsive disorder. Despite established efficacy, many youths receiving either therapy remain symptomatic after acute treatment. Regardless of the rationale for persistent symptoms,...

[Spinal administration of alpha 2-adrenoceptor agonists and opioids or local anaesthetic agents].

Schmerz (Berlin, Germany)

Motsch J.
PMID: 12799873
Schmerz. 1996 Feb 15;10(1):21-6. doi: 10.1007/s004829600010.

The effects of combined spinal administration of alpha(2)-adrenoceptor agonists, local anaesthetics, and opioids have been extensively studied. The motor and the sensory block of spinal and epidural anaesthesia is enhanced and prolonged by the combination of clonidine with the...

Determination of elemental carbon emission.

Environmental monitoring and assessment

Mniszek W, Wypych J, Zielonka U.
PMID: 24221230
Environ Monit Assess. 1994 Jan;29(1):41-52. doi: 10.1007/BF00546777.

The studies on elemental carbon content in the atmospheric air, performed at the air monitoring station in Katowice (Poland), have revealed violations of allowable maximum average annual and diurnal concentrations. Elemental carbon is introduced into the atmosphere mainly as...

Successes and Challenges of an IT-Based Health Behaviour Change Program to Increase Physical Activity.

Studies in health technology and informatics

Kolt GS, Duncan MJ, Vandelanotte C, Rosenkranz RR, Maeder AJ, Savage TN, Tague R, Van Itallie A, Mummery WK, Caperchione CM.
PMID: 32141877
Stud Health Technol Inform. 2020 Mar 02;268:31-43. doi: 10.3233/SHTI200004.

Health behaviour change programs that utilise IT-based delivery have great potential to improve health. Whilst more static Web 1.0 technologies have been somewhat effective, they often failed to promote longer-term user engagement required for greater health promotion impact. With...

Apparatus design for measuring of the strain dependence of the Seebeck coefficient of single crystals.

The Review of scientific instruments

Qian T, Mutch J, Wu L, Went P, Jiang Q, Malinowski P, Yang J, Chu JH.
PMID: 32113413
Rev Sci Instrum. 2020 Feb 01;91(2):023902. doi: 10.1063/1.5127530.

We present the design and construction of an apparatus that measures the Seebeck coefficient of single crystals under in situ tunable strain at cryogenic temperatures. A home-built three piezostack apparatus applies uni-axial stress to a single crystalline sample and...

Sleep and physical activity in relation to all-cause, cardiovascular disease and cancer mortality risk.

British journal of sports medicine

Huang BH, Duncan MJ, Cistulli PA, Nassar N, Hamer M, Stamatakis E.
PMID: 34187783
Br J Sports Med. 2021 Jun 29; doi: 10.1136/bjsports-2021-104046. Epub 2021 Jun 29.

OBJECTIVES: Although both physical inactivity and poor sleep are deleteriously associated with mortality, the joint effects of these two behaviours remain unknown. This study aimed to investigate the joint association of physical activity (PA) and sleep with all-cause and...

Toxic effect of antidepressants on male reproductive system cells: evaluation of possible fertility reduction mechanism.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society

Solek P, Mytych J, Tabecka-Lonczynska A, Sowa-Kucma M, Koziorowski M.
PMID: 34810289
J Physiol Pharmacol. 2021 Jun;72(3). doi: 10.26402/jpp.2021.3.06. Epub 2021 Nov 19.

Depression is acknowledged as a major public health problem. Pharmacological treatment may cause adverse drug reactions and sexual side effects. At the same time, the knowledge of the molecular mechanisms associated with antidepressant-mediated toxicity to reproductive cells is fragmentary....

Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target.

Frontiers in immunology

Kroenke MA, Barger TE, Hu J, Miller MJ, Kalenian K, He L, Hsu H, Bartley Y, Chow VF, Teixeira Dos Santos MC, Sullivan BA, Cheng LE, Parnes JR, Padaki R, Kuhns S, Mytych DT.
PMID: 34970265
Front Immunol. 2021 Dec 14;12:782788. doi: 10.3389/fimmu.2021.782788. eCollection 2021.

AMG 966 is a bi-specific, heteroimmunoglobulin molecule that binds both tumor necrosis factor alpha (TNFα) and TNF-like ligand 1A (TL1A). In a first-in-human clinical study in healthy volunteers, AMG 966 elicited anti-drug antibodies (ADA) in 53 of 54 subjects...

Research in psychotherapy (Milano)

Doležal P, Čevelíček M, Řiháček T, Roubal J, Hytych R, Ukropová L.
PMID: 32913795
Res Psychother. 2019 Jul 30;22(2):354. doi: 10.4081/ripppo.2019.354. eCollection 2019 Aug 09.

The present case study aims to explore the unfolding of the working alliance in a case that ended with the client dropping out of psychotherapy, unilaterally cutting off her contact with the therapist. However, both quantitative and qualitative outcome...

The transport-structural correspondence across the nematic phase transition probed by elasto X-ray diffraction.

Nature materials

Sanchez JJ, Malinowski P, Mutch J, Liu J, Kim JW, Ryan PJ, Chu JH.
PMID: 34446865
Nat Mater. 2021 Nov;20(11):1519-1524. doi: 10.1038/s41563-021-01082-4. Epub 2021 Aug 26.

Electronic nematicity in iron pnictide materials is coupled to both the lattice and the conducting electrons, which allows both structural and transport observables to probe nematic fluctuations and the order parameter. Here we combine simultaneous transport and X-ray diffraction...

Showing 1 to 12 of 78 entries