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Showing 1 to 12 of 16 entries
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Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation.

Stem cells international

Van den Bogerd B, Zakaria N, Matthyssen S, Koppen C, Ní Dhubhghaill S.
PMID: 32089707
Stem Cells Int. 2020 Feb 05;2020:5891393. doi: 10.1155/2020/5891393. eCollection 2020.

Ex vivo grown human corneal endothelial cells (HCEnC) are a new emerging treatment option to treat visually impaired patients aimed at alleviating the current global donor shortage. Expanding HCEnC is still challenging, and obtaining cells in sufficient quantities is...

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Van den Bogerd B, Zakaria N, Matthyssen S, et al. Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation. Stem Cells Int. 2020;2020:5891393doi: 10.1155/2020/5891393.
Van den Bogerd, B., Zakaria, N., Matthyssen, S., Koppen, C., & Ní Dhubhghaill, S. (2020). Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation. Stem cells international, 20205891393. https://doi.org/10.1155/2020/5891393
Van den Bogerd, Bert, et al. "Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation." Stem cells international vol. 2020 (2020): 5891393. doi: https://doi.org/10.1155/2020/5891393
Van den Bogerd B, Zakaria N, Matthyssen S, Koppen C, Ní Dhubhghaill S. Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation. Stem Cells Int. 2020 Feb 05;2020:5891393. doi: 10.1155/2020/5891393. eCollection 2020. PMID: 32089707; PMCID: PMC7025074.
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Approaches for corneal endothelium regenerative medicine.

Progress in retinal and eye research

Català P, Thuret G, Skottman H, Mehta JS, Parekh M, Ní Dhubhghaill S, Collin RWJ, Nuijts RMMA, Ferrari S, LaPointe VLS, Dickman MM.
PMID: 34237411
Prog Retin Eye Res. 2021 Jul 06;100987. doi: 10.1016/j.preteyeres.2021.100987. Epub 2021 Jul 06.

The state of the art therapy for treating corneal endothelial disease is transplantation. Advances in the reproducibility and accessibility of surgical techniques are increasing the number of corneal transplants, thereby causing a global deficit of donor corneas and leaving...

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Català P, Thuret G, Skottman H, et al. Approaches for corneal endothelium regenerative medicine. Prog Retin Eye Res. 2021;100987doi: 10.1016/j.preteyeres.2021.100987.
Català, P., Thuret, G., Skottman, H., Mehta, J. S., Parekh, M., Ní Dhubhghaill, S., Collin, R. W. J., Nuijts, R. M. M. A., Ferrari, S., LaPointe, V. L. S., & Dickman, M. M. (2021). Approaches for corneal endothelium regenerative medicine. Progress in retinal and eye research, 100987. https://doi.org/10.1016/j.preteyeres.2021.100987
Català, Pere, et al. "Approaches for corneal endothelium regenerative medicine." Progress in retinal and eye research vol. (2021): 100987. doi: https://doi.org/10.1016/j.preteyeres.2021.100987
Català P, Thuret G, Skottman H, Mehta JS, Parekh M, Ní Dhubhghaill S, Collin RWJ, Nuijts RMMA, Ferrari S, LaPointe VLS, Dickman MM. Approaches for corneal endothelium regenerative medicine. Prog Retin Eye Res. 2021 Jul 06;100987. doi: 10.1016/j.preteyeres.2021.100987. Epub 2021 Jul 06. PMID: 34237411.
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Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Transplantation in Aniridia-Associated Keratopathy-A Single-Center Retrospective Analysis.

Cornea

Behaegel J, Tassignon MJ, Lagali N, Consejo A, Koppen C, Ní Dhubhghaill S.
PMID: 33928920
Cornea. 2022 Jan 01;41(1):69-77. doi: 10.1097/ICO.0000000000002729.

PURPOSE: To assess the efficacy and safety of human leukocyte antigen-matched allogeneic cultivated limbal epithelial stem cell grafts in the treatment of aniridia-associated keratopathy (AAK).METHODS: Six eyes of 6 patients with severe AAK received an allogeneic stem cell graft...

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Behaegel J, Tassignon MJ, Lagali N, et al. Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Transplantation in Aniridia-Associated Keratopathy-A Single-Center Retrospective Analysis. Cornea. 2022;41(1):69-77doi: 10.1097/ICO.0000000000002729.
Behaegel, J., Tassignon, M. J., Lagali, N., Consejo, A., Koppen, C., & Ní Dhubhghaill, S. (2022). Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Transplantation in Aniridia-Associated Keratopathy-A Single-Center Retrospective Analysis. Cornea, 41(1), 69-77. https://doi.org/10.1097/ICO.0000000000002729
Behaegel, Joséphine, et al. "Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Transplantation in Aniridia-Associated Keratopathy-A Single-Center Retrospective Analysis." Cornea vol. 41,1 (2022): 69-77. doi: https://doi.org/10.1097/ICO.0000000000002729
Behaegel J, Tassignon MJ, Lagali N, Consejo A, Koppen C, Ní Dhubhghaill S. Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Transplantation in Aniridia-Associated Keratopathy-A Single-Center Retrospective Analysis. Cornea. 2022 Jan 01;41(1):69-77. doi: 10.1097/ICO.0000000000002729. PMID: 33928920; PMCID: PMC8647694.
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Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies.

Stem cells international

Haagdorens M, Van Acker SI, Van Gerwen V, Ní Dhubhghaill S, Koppen C, Tassignon MJ, Zakaria N.
PMID: 26788074
Stem Cells Int. 2016;2016:9798374. doi: 10.1155/2016/9798374. Epub 2015 Dec 14.

Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition leading to decreased visual acuity, photophobia, and ocular pain. To restore the ocular surface in advanced stem cell deficient corneas, an autologous or allogenic limbal...

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Haagdorens M, Van Acker SI, Van Gerwen V, et al. Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies. Stem Cells Int. 2015;2016:9798374doi: 10.1155/2016/9798374.
Haagdorens, M., Van Acker, S. I., Van Gerwen, V., Ní Dhubhghaill, S., Koppen, C., Tassignon, M. J., & Zakaria, N. (2016). Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies. Stem cells international, 20169798374. https://doi.org/10.1155/2016/9798374
Haagdorens, Michel, et al. "Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies." Stem cells international vol. 2016 (2016): 9798374. doi: https://doi.org/10.1155/2016/9798374
Haagdorens M, Van Acker SI, Van Gerwen V, Ní Dhubhghaill S, Koppen C, Tassignon MJ, Zakaria N. Limbal Stem Cell Deficiency: Current Treatment Options and Emerging Therapies. Stem Cells Int. 2016;2016:9798374. doi: 10.1155/2016/9798374. Epub 2015 Dec 14. PMID: 26788074; PMCID: PMC4691643.
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Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?.

Translational vision science & technology

Van den Bogerd B, Zakaria N, Adam B, Matthyssen S, Koppen C, Ní Dhubhghaill S.
PMID: 31772824
Transl Vis Sci Technol. 2019 Nov 15;8(6):13. doi: 10.1167/tvst.8.6.13. eCollection 2019 Nov.

Corneal endothelial dysfunction is one of the leading causes of corneal edema and visual impairment, requiring corneal endothelial transplantation. The treatments are limited, however, by both logistics and a global donor shortage. As a result, corneal researchers are striving...

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Van den Bogerd B, Zakaria N, Adam B, et al. Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?. Transl Vis Sci Technol. 2019;8(6):13doi: 10.1167/tvst.8.6.13.
Van den Bogerd, B., Zakaria, N., Adam, B., Matthyssen, S., Koppen, C., & Ní Dhubhghaill, S. (2019). Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?. Translational vision science & technology, 8(6), 13. https://doi.org/10.1167/tvst.8.6.13
Van den Bogerd, Bert, et al. "Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?." Translational vision science & technology vol. 8,6 (2019): 13. doi: https://doi.org/10.1167/tvst.8.6.13
Van den Bogerd B, Zakaria N, Adam B, Matthyssen S, Koppen C, Ní Dhubhghaill S. Corneal Endothelial Cells Over the Past Decade: Are We Missing the Mark(er)?. Transl Vis Sci Technol. 2019 Nov 15;8(6):13. doi: 10.1167/tvst.8.6.13. eCollection 2019 Nov. PMID: 31772824; PMCID: PMC6859829.
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New developments in corneal endothelial cell replacement.

Acta ophthalmologica

Spinozzi D, Miron A, Bruinsma M, Dapena I, Kocaba V, Jager MJ, Melles GRJ, Ni Dhubhghaill S, Oellerich S.
PMID: 33369235
Acta Ophthalmol. 2021 Nov;99(7):712-729. doi: 10.1111/aos.14722. Epub 2020 Dec 24.

Corneal transplantation is currently the most effective treatment to restore corneal clarity in patients with endothelial disorders. Endothelial transplantation, either by Descemet membrane endothelial keratoplasty (DMEK) or by Descemet stripping (automated) endothelial keratoplasty (DS(A)EK), is a surgical approach that...

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Spinozzi D, Miron A, Bruinsma M, et al. New developments in corneal endothelial cell replacement. Acta Ophthalmol. 2020;99(7):712-729doi: 10.1111/aos.14722.
Spinozzi, D., Miron, A., Bruinsma, M., Dapena, I., Kocaba, V., Jager, M. J., Melles, G. R. J., Ni Dhubhghaill, S., & Oellerich, S. (2021). New developments in corneal endothelial cell replacement. Acta ophthalmologica, 99(7), 712-729. https://doi.org/10.1111/aos.14722
Spinozzi, Daniele, et al. "New developments in corneal endothelial cell replacement." Acta ophthalmologica vol. 99,7 (2021): 712-729. doi: https://doi.org/10.1111/aos.14722
Spinozzi D, Miron A, Bruinsma M, Dapena I, Kocaba V, Jager MJ, Melles GRJ, Ni Dhubhghaill S, Oellerich S. New developments in corneal endothelial cell replacement. Acta Ophthalmol. 2021 Nov;99(7):712-729. doi: 10.1111/aos.14722. Epub 2020 Dec 24. PMID: 33369235.
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Clinical and Surgical Outcome of a Supplementary Multifocal Intraocular Lens Implanted with a Bag-In-the-Lens Intraocular Lens: 5-Year Follow-Up.

Ophthalmic research

Verdonck T, Werner L, Ní Dhubhghaill S, Tassignon MJ.
PMID: 33326968
Ophthalmic Res. 2021;64(3):503-511. doi: 10.1159/000513790. Epub 2020 Dec 16.

INTRODUCTION: To assess the postoperative outcome and patient-reported satisfaction, spectacle independence, and dysphotopsia after implantation with the mutifocal Rayner Sulcoflex supplementary intraocular lens (sIOL).MATERIALS AND METHODS: We analyzed the outcome of all patients implanted with a multifocal sIOL between...

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Verdonck T, Werner L, Ní Dhubhghaill S, et al. Clinical and Surgical Outcome of a Supplementary Multifocal Intraocular Lens Implanted with a Bag-In-the-Lens Intraocular Lens: 5-Year Follow-Up. Ophthalmic Res. 2020;64(3):503-511doi: 10.1159/000513790.
Verdonck, T., Werner, L., Ní Dhubhghaill, S., & Tassignon, M. J. (2021). Clinical and Surgical Outcome of a Supplementary Multifocal Intraocular Lens Implanted with a Bag-In-the-Lens Intraocular Lens: 5-Year Follow-Up. Ophthalmic research, 64(3), 503-511. https://doi.org/10.1159/000513790
Verdonck, Thomas, et al. "Clinical and Surgical Outcome of a Supplementary Multifocal Intraocular Lens Implanted with a Bag-In-the-Lens Intraocular Lens: 5-Year Follow-Up." Ophthalmic research vol. 64,3 (2021): 503-511. doi: https://doi.org/10.1159/000513790
Verdonck T, Werner L, Ní Dhubhghaill S, Tassignon MJ. Clinical and Surgical Outcome of a Supplementary Multifocal Intraocular Lens Implanted with a Bag-In-the-Lens Intraocular Lens: 5-Year Follow-Up. Ophthalmic Res. 2021;64(3):503-511. doi: 10.1159/000513790. Epub 2020 Dec 16. PMID: 33326968.
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Proliferation Increasing Genetic Engineering in Human Corneal Endothelial Cells: A Literature Review.

Frontiers in medicine

Arras W, Vercammen H, Ní Dhubhghaill S, Koppen C, Van den Bogerd B.
PMID: 34268324
Front Med (Lausanne). 2021 Jun 29;8:688223. doi: 10.3389/fmed.2021.688223. eCollection 2021.

The corneal endothelium is the inner layer of the cornea. Despite comprising only a monolayer of cells, dysfunction of this layer renders millions of people visually impaired worldwide. Currently, corneal endothelial transplantation is the only viable means of restoring...

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Arras W, Vercammen H, Ní Dhubhghaill S, et al. Proliferation Increasing Genetic Engineering in Human Corneal Endothelial Cells: A Literature Review. Front Med (Lausanne). 2021;8:688223doi: 10.3389/fmed.2021.688223.
Arras, W., Vercammen, H., Ní Dhubhghaill, S., Koppen, C., & Van den Bogerd, B. (2021). Proliferation Increasing Genetic Engineering in Human Corneal Endothelial Cells: A Literature Review. Frontiers in medicine, 8688223. https://doi.org/10.3389/fmed.2021.688223
Arras, Wout, et al. "Proliferation Increasing Genetic Engineering in Human Corneal Endothelial Cells: A Literature Review." Frontiers in medicine vol. 8 (2021): 688223. doi: https://doi.org/10.3389/fmed.2021.688223
Arras W, Vercammen H, Ní Dhubhghaill S, Koppen C, Van den Bogerd B. Proliferation Increasing Genetic Engineering in Human Corneal Endothelial Cells: A Literature Review. Front Med (Lausanne). 2021 Jun 29;8:688223. doi: 10.3389/fmed.2021.688223. eCollection 2021. PMID: 34268324; PMCID: PMC8275833.
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Forecasting Progressive Trends in Keratoconus by Means of a Time Delay Neural Network.

Journal of clinical medicine

Jiménez-García M, Issarti I, Kreps EO, Ní Dhubhghaill S, Koppen C, Varssano D, Rozema JJ.
PMID: 34362023
J Clin Med. 2021 Jul 22;10(15). doi: 10.3390/jcm10153238.

Early and accurate detection of keratoconus progression is particularly important for the prudent, cost-effective use of corneal cross-linking and judicious timing of clinical follow-up visits. The aim of this study was to verify whether a progression could be predicted...

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Jiménez-García M, Issarti I, Kreps EO, et al. Forecasting Progressive Trends in Keratoconus by Means of a Time Delay Neural Network. J Clin Med. 2021;10(15)doi: 10.3390/jcm10153238.
Jiménez-García, M., Issarti, I., Kreps, E. O., Ní Dhubhghaill, S., Koppen, C., Varssano, D., Rozema, J. J. (2021). Forecasting Progressive Trends in Keratoconus by Means of a Time Delay Neural Network. Journal of clinical medicine, 10(15), . https://doi.org/10.3390/jcm10153238
Jiménez-García, Marta, et al. "Forecasting Progressive Trends in Keratoconus by Means of a Time Delay Neural Network." Journal of clinical medicine vol. 10,15 (2021). doi: https://doi.org/10.3390/jcm10153238
Jiménez-García M, Issarti I, Kreps EO, Ní Dhubhghaill S, Koppen C, Varssano D, Rozema JJ. Forecasting Progressive Trends in Keratoconus by Means of a Time Delay Neural Network. J Clin Med. 2021 Jul 22;10(15). doi: 10.3390/jcm10153238. PMID: 34362023; PMCID: PMC8347247.
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Densitometry marks delineating the affected area in keratoconus: clinical suitability of a new descriptive system based on its repeatability and reproducibility.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)

Jiménez-García M, Ní Dhubhghaill S, Hershko S, Koppen C, Rozema JJ.
PMID: 33860971
Ophthalmic Physiol Opt. 2021 Jul;41(4):748-756. doi: 10.1111/opo.12821. Epub 2021 Apr 16.

PURPOSE: To present a descriptive system for the elliptic demarcation area seen in keratoconus densitometry maps (obtained with a Scheimpflug tomographer) and to evaluate its suitability for clinical practice.METHODS: The subjects were 30 keratoconus patients at different stages and...

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Jiménez-García M, Ní Dhubhghaill S, Hershko S, et al. Densitometry marks delineating the affected area in keratoconus: clinical suitability of a new descriptive system based on its repeatability and reproducibility. Ophthalmic Physiol Opt. 2021;41(4):748-756doi: 10.1111/opo.12821.
Jiménez-García, M., Ní Dhubhghaill, S., Hershko, S., Koppen, C., & Rozema, J. J. (2021). Densitometry marks delineating the affected area in keratoconus: clinical suitability of a new descriptive system based on its repeatability and reproducibility. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 41(4), 748-756. https://doi.org/10.1111/opo.12821
Jiménez-García, Marta, et al. "Densitometry marks delineating the affected area in keratoconus: clinical suitability of a new descriptive system based on its repeatability and reproducibility." Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) vol. 41,4 (2021): 748-756. doi: https://doi.org/10.1111/opo.12821
Jiménez-García M, Ní Dhubhghaill S, Hershko S, Koppen C, Rozema JJ. Densitometry marks delineating the affected area in keratoconus: clinical suitability of a new descriptive system based on its repeatability and reproducibility. Ophthalmic Physiol Opt. 2021 Jul;41(4):748-756. doi: 10.1111/opo.12821. Epub 2021 Apr 16. PMID: 33860971.
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An Overview of Advanced .

Tissue engineering. Part B, Reviews

Van Meenen J, Ní Dhubhghaill S, Van den Bogerd B, Koppen C.
PMID: 33878935
Tissue Eng Part B Rev. 2021 Jun 11; doi: 10.1089/ten.TEB.2021.0031. Epub 2021 Jun 11.

The cornea is an important barrier to consider when developing ophthalmic formulations, but proper modeling of this multilayered tissue remains a challenge. This is due to the varying properties associated with each layer in addition to the dynamics of...

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Van Meenen J, Ní Dhubhghaill S, Van den Bogerd B, et al. An Overview of Advanced . Tissue Eng Part B Rev. 2021;doi: 10.1089/ten.TEB.2021.0031.
Van Meenen, J., Ní Dhubhghaill, S., Van den Bogerd, B., & Koppen, C. (2021). An Overview of Advanced . Tissue engineering. Part B, Reviews, . https://doi.org/10.1089/ten.TEB.2021.0031
Van Meenen, Joris, et al. "An Overview of Advanced ." Tissue engineering. Part B, Reviews vol. (2021). doi: https://doi.org/10.1089/ten.TEB.2021.0031
Van Meenen J, Ní Dhubhghaill S, Van den Bogerd B, Koppen C. An Overview of Advanced . Tissue Eng Part B Rev. 2021 Jun 11; doi: 10.1089/ten.TEB.2021.0031. Epub 2021 Jun 11. PMID: 33878935.
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Scheimpflug Analysis of Centration and Bending of Posterior Chamber Phakic Intraocular Lenses.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Tassignon MJ, Rozema JJ, Ní Dhubhghaill S.
PMID: 26107582
Asia Pac J Ophthalmol (Phila). 2014 May-Jun;3(3):136-40. doi: 10.1097/APO.0000000000000004.

PURPOSE: The aim of the study was to present a novel technique for the assessment of postoperative centration and bending in phakic intraocular lens (PIOL), illustrated through 4 patient examples.DESIGN: This was a prospective observational study.METHODS: Four patients (7...

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Tassignon MJ, Rozema JJ, Ní Dhubhghaill S. Scheimpflug Analysis of Centration and Bending of Posterior Chamber Phakic Intraocular Lenses. Asia Pac J Ophthalmol (Phila). 2014;3(3):136-40doi: 10.1097/APO.0000000000000004.
Tassignon, M. J., Rozema, J. J., & Ní Dhubhghaill, S. (2014). Scheimpflug Analysis of Centration and Bending of Posterior Chamber Phakic Intraocular Lenses. Asia-Pacific journal of ophthalmology (Philadelphia, Pa.), 3(3), 136-40. https://doi.org/10.1097/APO.0000000000000004
Tassignon, Marie-José B R, et al. "Scheimpflug Analysis of Centration and Bending of Posterior Chamber Phakic Intraocular Lenses." Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) vol. 3,3 (2014): 136-40. doi: https://doi.org/10.1097/APO.0000000000000004
Tassignon MJ, Rozema JJ, Ní Dhubhghaill S. Scheimpflug Analysis of Centration and Bending of Posterior Chamber Phakic Intraocular Lenses. Asia Pac J Ophthalmol (Phila). 2014 May-Jun;3(3):136-40. doi: 10.1097/APO.0000000000000004. PMID: 26107582.
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Showing 1 to 12 of 16 entries