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Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling.

EXCLI journal

Yang W, Burkhardt B, Fischer L, Beirow M, Bork N, Wönne EC, Wagner C, Husen B, Zeilinger K, Liu L, Nussler AK.
PMID: 27004051
EXCLI J. 2015 Dec 22;14:1273-90. doi: 10.17179/excli2015-734. eCollection 2015.

Aging is characterized by a progressive decrease of cellular functions, because cells gradually lose their capacity to respond to injury. Increased oxidative stress is considered to be one of the major contributors to age-related changes in all organs including...

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Yang W, Burkhardt B, Fischer L, et al. Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. EXCLI J. 2015;14:1273-90doi: 10.17179/excli2015-734.
Yang, W., Burkhardt, B., Fischer, L., Beirow, M., Bork, N., Wönne, E. C., Wagner, C., Husen, B., Zeilinger, K., Liu, L., & Nussler, A. K. (2015). Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. EXCLI journal, 141273-90. https://doi.org/10.17179/excli2015-734
Yang, Wei, et al. "Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling." EXCLI journal vol. 14 (2015): 1273-90. doi: https://doi.org/10.17179/excli2015-734
Yang W, Burkhardt B, Fischer L, Beirow M, Bork N, Wönne EC, Wagner C, Husen B, Zeilinger K, Liu L, Nussler AK. Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. EXCLI J. 2015 Dec 22;14:1273-90. doi: 10.17179/excli2015-734. eCollection 2015. PMID: 27004051; PMCID: PMC4800781.
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The immune response after fracture trauma is different in old compared to young patients.

Immunity & ageing : I & A

Vester H, Huber-Lang MS, Kida Q, Scola A, van Griensven M, Gebhard F, Nüssler AK, Perl M.
PMID: 25620994
Immun Ageing. 2014 Dec 11;11(1):20. doi: 10.1186/s12979-014-0020-x. eCollection 2014.

BACKGROUND: Despite significant medical progress and improved treatment, surgical procedures of proximal femur fractures in older patients are still associated with a high postoperative complication and mortality rate. Recently, several authors investigated the phenomenon of immunoageing, indicating differences in...

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Vester H, Huber-Lang MS, Kida Q, et al. The immune response after fracture trauma is different in old compared to young patients. Immun Ageing. 2014;11(1):20doi: 10.1186/s12979-014-0020-x.
Vester, H., Huber-Lang, M. S., Kida, Q., Scola, A., van Griensven, M., Gebhard, F., Nüssler, A. K., & Perl, M. (2014). The immune response after fracture trauma is different in old compared to young patients. Immunity & ageing : I & A, 11(1), 20. https://doi.org/10.1186/s12979-014-0020-x
Vester, Helen, et al. "The immune response after fracture trauma is different in old compared to young patients." Immunity & ageing : I & A vol. 11,1 (2014): 20. doi: https://doi.org/10.1186/s12979-014-0020-x
Vester H, Huber-Lang MS, Kida Q, Scola A, van Griensven M, Gebhard F, Nüssler AK, Perl M. The immune response after fracture trauma is different in old compared to young patients. Immun Ageing. 2014 Dec 11;11(1):20. doi: 10.1186/s12979-014-0020-x. eCollection 2014. PMID: 25620994; PMCID: PMC4305233.
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Rhythmic changes of hydroxymethylglutaryl coenzyme a reductase activity in livers of fed and fasted rats.

FEBS letters

Hamprecht B, Nüssler C, Lynen F.
PMID: 11947160
FEBS Lett. 1969 Jul;4(2):117-121. doi: 10.1016/0014-5793(69)80210-3.

No abstract available.

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Hamprecht B, Nüssler C, Lynen F. Rhythmic changes of hydroxymethylglutaryl coenzyme a reductase activity in livers of fed and fasted rats. FEBS Lett. 1969;4(2):117-121doi: 10.1016/0014-5793(69)80210-3.
Hamprecht, B., Nüssler, C., & Lynen, F. (1969). Rhythmic changes of hydroxymethylglutaryl coenzyme a reductase activity in livers of fed and fasted rats. FEBS letters, 4(2), 117-121. https://doi.org/10.1016/0014-5793(69)80210-3
Hamprecht, B, et al. "Rhythmic changes of hydroxymethylglutaryl coenzyme a reductase activity in livers of fed and fasted rats." FEBS letters vol. 4,2 (1969): 117-121. doi: https://doi.org/10.1016/0014-5793(69)80210-3
Hamprecht B, Nüssler C, Lynen F. Rhythmic changes of hydroxymethylglutaryl coenzyme a reductase activity in livers of fed and fasted rats. FEBS Lett. 1969 Jul;4(2):117-121. doi: 10.1016/0014-5793(69)80210-3. PMID: 11947160.
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Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics.

Diabetology & metabolic syndrome

Pscherer S, Freude T, Forst T, Nussler AK, Braun KF, Ehnert S.
PMID: 24004910
Diabetol Metab Syndr. 2013 Aug 31;5(1):48. doi: 10.1186/1758-5996-5-48.

BACKGROUND: The single-center, open-label, four-arm, exploratory study investigates the relation of different anti-diabetics to serum levels of active TGF-β, a known pro-fibrotic stimulus, before and after a defined test meal.FINDINGS: We investigated sera of patients with type 2 diabetes...

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Pscherer S, Freude T, Forst T, et al. Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics. Diabetol Metab Syndr. 2013;5(1):48doi: 10.1186/1758-5996-5-48.
Pscherer, S., Freude, T., Forst, T., Nussler, A. K., Braun, K. F., & Ehnert, S. (2013). Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics. Diabetology & metabolic syndrome, 5(1), 48. https://doi.org/10.1186/1758-5996-5-48
Pscherer, Stefan, et al. "Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics." Diabetology & metabolic syndrome vol. 5,1 (2013): 48. doi: https://doi.org/10.1186/1758-5996-5-48
Pscherer S, Freude T, Forst T, Nussler AK, Braun KF, Ehnert S. Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics. Diabetol Metab Syndr. 2013 Aug 31;5(1):48. doi: 10.1186/1758-5996-5-48. PMID: 24004910; PMCID: PMC3847073.
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Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia.

Aging and disease

Liao Y, Peng Z, Chen L, Zhang Y, Cheng Q, Nüssler AK, Bao W, Liu L, Yang W.
PMID: 30705776
Aging Dis. 2019 Feb 01;10(1):157-173. doi: 10.14336/AD.2018.0325. eCollection 2019 Feb.

Skeletal muscle aging is characterized by decline in skeletal muscle mass and function along with growing age, which consequently leads to age-related sarcopenia, if without any preventive timely treatment. Moreover, age-related sarcopenia in elder people would contribute to falls...

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Liao Y, Peng Z, Chen L, et al. Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia. Aging Dis. 2019;10(1):157-173doi: 10.14336/AD.2018.0325.
Liao, Y., Peng, Z., Chen, L., Zhang, Y., Cheng, Q., Nüssler, A. K., Bao, W., Liu, L., & Yang, W. (2019). Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia. Aging and disease, 10(1), 157-173. https://doi.org/10.14336/AD.2018.0325
Liao, Yuxiao, et al. "Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia." Aging and disease vol. 10,1 (2019): 157-173. doi: https://doi.org/10.14336/AD.2018.0325
Liao Y, Peng Z, Chen L, Zhang Y, Cheng Q, Nüssler AK, Bao W, Liu L, Yang W. Prospective Views for Whey Protein and/or Resistance Training Against Age-related Sarcopenia. Aging Dis. 2019 Feb 01;10(1):157-173. doi: 10.14336/AD.2018.0325. eCollection 2019 Feb. PMID: 30705776; PMCID: PMC6345331.
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Organ transplantation and gut microbiota: current reviews and future challenges.

American journal of translational research

Xiao J, Peng Z, Liao Y, Sun H, Chen W, Chen X, Wei Z, Yang C, Nüssler AK, Liu J, Yang W.
PMID: 30662590
Am J Transl Res. 2018 Nov 15;10(11):3330-3344. eCollection 2018.

Organ transplantation is often the only effective treatment for patients with end-stage diseases, such as heart, liver, kidney and small bowel failure and is carried out frequently worldwide. Still the post-transplantation complications remain health- and life-threatening outcome that needed...

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Xiao J, Peng Z, Liao Y, et al. Organ transplantation and gut microbiota: current reviews and future challenges. Am J Transl Res. 2018;10(11):3330-3344
Xiao, J., Peng, Z., Liao, Y., Sun, H., Chen, W., Chen, X., Wei, Z., Yang, C., Nüssler, A. K., Liu, J., & Yang, W. (2018). Organ transplantation and gut microbiota: current reviews and future challenges. American journal of translational research, 10(11), 3330-3344.
Xiao, Jie, et al. "Organ transplantation and gut microbiota: current reviews and future challenges." American journal of translational research vol. 10,11 (2018): 3330-3344.
Xiao J, Peng Z, Liao Y, Sun H, Chen W, Chen X, Wei Z, Yang C, Nüssler AK, Liu J, Yang W. Organ transplantation and gut microbiota: current reviews and future challenges. Am J Transl Res. 2018 Nov 15;10(11):3330-3344. eCollection 2018. PMID: 30662590; PMCID: PMC6291689.
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Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative Potential.

Stem cells international

Ungefroren H, Hyder A, Schulze M, Fawzy El-Sayed KM, Grage-Griebenow E, Nussler AK, Fändrich F.
PMID: 26798361
Stem Cells Int. 2016;2016:7132751. doi: 10.1155/2016/7132751. Epub 2015 Dec 20.

Adult stem or programmable cells hold great promise in diseases in which damaged or nonfunctional cells need to be replaced. We have recently demonstrated that peripheral blood monocytes can be differentiated in vitro into cells resembling specialized cell types...

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Ungefroren H, Hyder A, Schulze M, et al. Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative Potential. Stem Cells Int. 2015;2016:7132751doi: 10.1155/2016/7132751.
Ungefroren, H., Hyder, A., Schulze, M., Fawzy El-Sayed, K. M., Grage-Griebenow, E., Nussler, A. K., & Fändrich, F. (2016). Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative Potential. Stem cells international, 20167132751. https://doi.org/10.1155/2016/7132751
Ungefroren, Hendrik, et al. "Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative Potential." Stem cells international vol. 2016 (2016): 7132751. doi: https://doi.org/10.1155/2016/7132751
Ungefroren H, Hyder A, Schulze M, Fawzy El-Sayed KM, Grage-Griebenow E, Nussler AK, Fändrich F. Peripheral Blood Monocytes as Adult Stem Cells: Molecular Characterization and Improvements in Culture Conditions to Enhance Stem Cell Features and Proliferative Potential. Stem Cells Int. 2016;2016:7132751. doi: 10.1155/2016/7132751. Epub 2015 Dec 20. PMID: 26798361; PMCID: PMC4699085.
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Barriers and attitudes towards cervical cancer screening in primary healthcare in Poland - doctors' perspective.

BMC family practice

Nessler K, Ball F, Chan SKF, Chwalek M, Krztoń-Królewiecka A, Windak A.
PMID: 34969373
BMC Fam Pract. 2021 Dec 30;22(1):260. doi: 10.1186/s12875-021-01612-8.

BACKGROUND: Healthcare systems have adopted different strategies to reduce the burden of cervical cancer. In Poland, a population-based screening program was implemented in 2006, leading to a downward trend in cervical cancer burden. However, screening rates are still low...

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Nessler K, Ball F, Chan SKF, et al. Barriers and attitudes towards cervical cancer screening in primary healthcare in Poland - doctors' perspective. BMC Fam Pract. 2021;22(1):260doi: 10.1186/s12875-021-01612-8.
Nessler, K., Ball, F., Chan, S. K. F., Chwalek, M., Krztoń-Królewiecka, A., & Windak, A. (2021). Barriers and attitudes towards cervical cancer screening in primary healthcare in Poland - doctors' perspective. BMC family practice, 22(1), 260. https://doi.org/10.1186/s12875-021-01612-8
Nessler, Katarzyna, et al. "Barriers and attitudes towards cervical cancer screening in primary healthcare in Poland - doctors' perspective." BMC family practice vol. 22,1 (2021): 260. doi: https://doi.org/10.1186/s12875-021-01612-8
Nessler K, Ball F, Chan SKF, Chwalek M, Krztoń-Królewiecka A, Windak A. Barriers and attitudes towards cervical cancer screening in primary healthcare in Poland - doctors' perspective. BMC Fam Pract. 2021 Dec 30;22(1):260. doi: 10.1186/s12875-021-01612-8. PMID: 34969373.
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Osteolectin.

Signal transduction and targeted therapy

Ehnert S, Histing T, Nüssler AK.
PMID: 34234107
Signal Transduct Target Ther. 2021 Jul 07;6(1):257. doi: 10.1038/s41392-021-00680-7.

No abstract available.

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Ehnert S, Histing T, Nüssler AK. Osteolectin. Signal Transduct Target Ther. 2021;6(1):257doi: 10.1038/s41392-021-00680-7.
Ehnert, S., Histing, T., & Nüssler, A. K. (2021). Osteolectin. Signal transduction and targeted therapy, 6(1), 257. https://doi.org/10.1038/s41392-021-00680-7
Ehnert, Sabrina, et al. "Osteolectin." Signal transduction and targeted therapy vol. 6,1 (2021): 257. doi: https://doi.org/10.1038/s41392-021-00680-7
Ehnert S, Histing T, Nüssler AK. Osteolectin. Signal Transduct Target Ther. 2021 Jul 07;6(1):257. doi: 10.1038/s41392-021-00680-7. PMID: 34234107; PMCID: PMC8263755.
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A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation.

Journal of materials science. Materials in medicine

Weng W, Zanetti F, Bovard D, Braun B, Ehnert S, Uynuk-Ool T, Histing T, Hoeng J, Nussler AK, Aspera-Werz RH.
PMID: 34524552
J Mater Sci Mater Med. 2021 Sep 15;32(9):124. doi: 10.1007/s10856-021-06601-y.

The extracellular matrix regulates cell survival, proliferation, and differentiation. In vitro two-dimensional cell experiments are typically performed on a plastic plate or a substrate of a single extracellular matrix constituent such as collagen or calcium phosphate. As these approaches...

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Weng W, Zanetti F, Bovard D, et al. A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation. J Mater Sci Mater Med. 2021;32(9):124doi: 10.1007/s10856-021-06601-y.
Weng, W., Zanetti, F., Bovard, D., Braun, B., Ehnert, S., Uynuk-Ool, T., Histing, T., Hoeng, J., Nussler, A. K., & Aspera-Werz, R. H. (2021). A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation. Journal of materials science. Materials in medicine, 32(9), 124. https://doi.org/10.1007/s10856-021-06601-y
Weng, Weidong, et al. "A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation." Journal of materials science. Materials in medicine vol. 32,9 (2021): 124. doi: https://doi.org/10.1007/s10856-021-06601-y
Weng W, Zanetti F, Bovard D, Braun B, Ehnert S, Uynuk-Ool T, Histing T, Hoeng J, Nussler AK, Aspera-Werz RH. A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation. J Mater Sci Mater Med. 2021 Sep 15;32(9):124. doi: 10.1007/s10856-021-06601-y. PMID: 34524552; PMCID: PMC8443471.
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Effects of immune cells on mesenchymal stem cells during fracture healing.

World journal of stem cells

Ehnert S, Relja B, Schmidt-Bleek K, Fischer V, Ignatius A, Linnemann C, Rinderknecht H, Huber-Lang M, Kalbitz M, Histing T, Nussler AK.
PMID: 34909117
World J Stem Cells. 2021 Nov 26;13(11):1667-1695. doi: 10.4252/wjsc.v13.i11.1667.

In vertebrates, bone is considered an osteoimmune system which encompasses functions of a locomotive organ, a mineral reservoir, a hormonal organ, a stem cell pool and a cradle for immune cells. This osteoimmune system is based on cooperatively acting...

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Ehnert S, Relja B, Schmidt-Bleek K, et al. Effects of immune cells on mesenchymal stem cells during fracture healing. World J Stem Cells. 2021;13(11):1667-1695doi: 10.4252/wjsc.v13.i11.1667.
Ehnert, S., Relja, B., Schmidt-Bleek, K., Fischer, V., Ignatius, A., Linnemann, C., Rinderknecht, H., Huber-Lang, M., Kalbitz, M., Histing, T., & Nussler, A. K. (2021). Effects of immune cells on mesenchymal stem cells during fracture healing. World journal of stem cells, 13(11), 1667-1695. https://doi.org/10.4252/wjsc.v13.i11.1667
Ehnert, Sabrina, et al. "Effects of immune cells on mesenchymal stem cells during fracture healing." World journal of stem cells vol. 13,11 (2021): 1667-1695. doi: https://doi.org/10.4252/wjsc.v13.i11.1667
Ehnert S, Relja B, Schmidt-Bleek K, Fischer V, Ignatius A, Linnemann C, Rinderknecht H, Huber-Lang M, Kalbitz M, Histing T, Nussler AK. Effects of immune cells on mesenchymal stem cells during fracture healing. World J Stem Cells. 2021 Nov 26;13(11):1667-1695. doi: 10.4252/wjsc.v13.i11.1667. PMID: 34909117; PMCID: PMC8641016.
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Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes.

World journal of stem cells

Aspera-Werz RH, Ehnert S, Müller M, Zhu S, Chen T, Weng W, Jacoby J, Nussler AK.
PMID: 32952862
World J Stem Cells. 2020 Aug 26;12(8):841-856. doi: 10.4252/wjsc.v12.i8.841.

BACKGROUND: Cigarette smoking (CS) is the most common method of consuming tobacco. Deleterious effects on bone integrity, increased incidence of fractures, and delayed fracture healing are all associated with CS. Over 150 of the 6500 molecular species contained in...

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Aspera-Werz RH, Ehnert S, Müller M, et al. Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes. World J Stem Cells. 2020;12(8):841-856doi: 10.4252/wjsc.v12.i8.841.
Aspera-Werz, R. H., Ehnert, S., Müller, M., Zhu, S., Chen, T., Weng, W., Jacoby, J., & Nussler, A. K. (2020). Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes. World journal of stem cells, 12(8), 841-856. https://doi.org/10.4252/wjsc.v12.i8.841
Aspera-Werz, Romina H, et al. "Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes." World journal of stem cells vol. 12,8 (2020): 841-856. doi: https://doi.org/10.4252/wjsc.v12.i8.841
Aspera-Werz RH, Ehnert S, Müller M, Zhu S, Chen T, Weng W, Jacoby J, Nussler AK. Assessment of tobacco heating system 2.4 on osteogenic differentiation of mesenchymal stem cells and primary human osteoblasts compared to conventional cigarettes. World J Stem Cells. 2020 Aug 26;12(8):841-856. doi: 10.4252/wjsc.v12.i8.841. PMID: 32952862; PMCID: PMC7477651.
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Showing 1 to 12 of 59 entries