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Showing 1 to 12 of 17 entries
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Neurosurgery: chemotherapy in conjunction with blood-brain barrier modification in patients with cerebral metastasis.

The Western journal of medicine

Neuwelt EA, Hill SA.
PMID: 18750025
West J Med. 1986 Jul;145(1):86.

No abstract available.

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Neuwelt EA, Hill SA. Neurosurgery: chemotherapy in conjunction with blood-brain barrier modification in patients with cerebral metastasis. West J Med. 1986;145(1):86
Neuwelt, E. A., & Hill, S. A. (1986). Neurosurgery: chemotherapy in conjunction with blood-brain barrier modification in patients with cerebral metastasis. The Western journal of medicine, 145(1), 86.
Neuwelt, E A, and Hill, S A. "Neurosurgery: chemotherapy in conjunction with blood-brain barrier modification in patients with cerebral metastasis." The Western journal of medicine vol. 145,1 (1986): 86.
Neuwelt EA, Hill SA. Neurosurgery: chemotherapy in conjunction with blood-brain barrier modification in patients with cerebral metastasis. West J Med. 1986 Jul;145(1):86. PMID: 18750025; PMCID: PMC1306825.
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siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli.

Cancer therapy

Tritz R, Mueller BM, Hickey MJ, Lin AH, Gomez GG, Hadwiger P, Sah DW, Muldoon L, Neuwelt EA, Kruse CA.
PMID: 19081762
Cancer Ther. 2008;6:865-876.

The PATZ1 gene encodes a transcription factor that belongs to the BTB/POZ group of transcriptional regulators and has been implicated as a transcriptional repressor. We cloned cDNA from glioma cell lines and found they expressed transcript variant 2 of...

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Tritz R, Mueller BM, Hickey MJ, et al. siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli. Cancer Ther. 2008;6:865-876
Tritz, R., Mueller, B. M., Hickey, M. J., Lin, A. H., Gomez, G. G., Hadwiger, P., Sah, D. W., Muldoon, L., Neuwelt, E. A., & Kruse, C. A. (2008). siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli. Cancer therapy, 6865-876.
Tritz, Richard, et al. "siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli." Cancer therapy vol. 6 (2008): 865-876.
Tritz R, Mueller BM, Hickey MJ, Lin AH, Gomez GG, Hadwiger P, Sah DW, Muldoon L, Neuwelt EA, Kruse CA. siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli. Cancer Ther. 2008;6:865-876. PMID: 19081762; PMCID: PMC2600477.
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Intra-renal splenosis mimicking a solid renal mass.

Ultrasound (Leeds, England)

Neufeld EA, Sekhon S, Gerscovich EO.
PMID: 29410693
Ultrasound. 2017 Aug;25(3):173-176. doi: 10.1177/1742271X17697752. Epub 2017 Mar 09.

We present the case of a young woman found to have an exophytic solid renal mass who was referred to our institution for ablation of said mass versus partial nephrectomy. The patient had a history of splenectomy. Ultrasound demonstrated...

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Neufeld EA, Sekhon S, Gerscovich EO. Intra-renal splenosis mimicking a solid renal mass. Ultrasound. 2017;25(3):173-176doi: 10.1177/1742271X17697752.
Neufeld, E. A., Sekhon, S., & Gerscovich, E. O. (2017). Intra-renal splenosis mimicking a solid renal mass. Ultrasound (Leeds, England), 25(3), 173-176. https://doi.org/10.1177/1742271X17697752
Neufeld, Ethan A, et al. "Intra-renal splenosis mimicking a solid renal mass." Ultrasound (Leeds, England) vol. 25,3 (2017): 173-176. doi: https://doi.org/10.1177/1742271X17697752
Neufeld EA, Sekhon S, Gerscovich EO. Intra-renal splenosis mimicking a solid renal mass. Ultrasound. 2017 Aug;25(3):173-176. doi: 10.1177/1742271X17697752. Epub 2017 Mar 09. PMID: 29410693; PMCID: PMC5794049.
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Photosynthetic responses of Miconia species to canopy openings in a lowland tropical rainforest.

Oecologia

Newell EA, McDonald EP, Strain BR, Denslow JS.
PMID: 28313857
Oecologia. 1993 May;94(1):49-56. doi: 10.1007/BF00317300.

We examined the photosynthetic acclimation of three tropical species of Miconia to canopy openings in a Costa Rican rainforest. The response of photosynthesis to canopy opening was very similar in Miconia affinis, M. gracilis, and M. nervosa, despite differences...

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Newell EA, McDonald EP, Strain BR, et al. Photosynthetic responses of Miconia species to canopy openings in a lowland tropical rainforest. Oecologia. 1993;94(1):49-56doi: 10.1007/BF00317300.
Newell, E. A., McDonald, E. P., Strain, B. R., & Denslow, J. S. (1993). Photosynthetic responses of Miconia species to canopy openings in a lowland tropical rainforest. Oecologia, 94(1), 49-56. https://doi.org/10.1007/BF00317300
Newell, Elizabeth A, et al. "Photosynthetic responses of Miconia species to canopy openings in a lowland tropical rainforest." Oecologia vol. 94,1 (1993): 49-56. doi: https://doi.org/10.1007/BF00317300
Newell EA, McDonald EP, Strain BR, Denslow JS. Photosynthetic responses of Miconia species to canopy openings in a lowland tropical rainforest. Oecologia. 1993 May;94(1):49-56. doi: 10.1007/BF00317300. PMID: 28313857.
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Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival.

Neuro-oncology advances

Kersch CN, Claunch CJ, Ambady P, Bucher E, Schwartz DL, Barajas RF, Iliff JJ, Risom T, Heiser L, Muldoon LL, Korkola JE, Gray JW, Neuwelt EA.
PMID: 32904984
Neurooncol Adv. 2020 Aug 03;2(1):vdaa093. doi: 10.1093/noajnl/vdaa093. eCollection 2020.

BACKGROUND: Glioblastoma is a rapidly fatal brain cancer that exhibits extensive intra- and intertumoral heterogeneity. Improving survival will require the development of personalized treatment strategies that can stratify tumors into subtypes that differ in therapeutic vulnerability and outcomes. Glioblastoma...

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Kersch CN, Claunch CJ, Ambady P, et al. Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival. Neurooncol Adv. 2020;2(1):vdaa093doi: 10.1093/noajnl/vdaa093.
Kersch, C. N., Claunch, C. J., Ambady, P., Bucher, E., Schwartz, D. L., Barajas, R. F., Iliff, J. J., Risom, T., Heiser, L., Muldoon, L. L., Korkola, J. E., Gray, J. W., & Neuwelt, E. A. (2020). Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival. Neuro-oncology advances, 2(1), vdaa093. https://doi.org/10.1093/noajnl/vdaa093
Kersch, Cymon N, et al. "Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival." Neuro-oncology advances vol. 2,1 (2020): vdaa093. doi: https://doi.org/10.1093/noajnl/vdaa093
Kersch CN, Claunch CJ, Ambady P, Bucher E, Schwartz DL, Barajas RF, Iliff JJ, Risom T, Heiser L, Muldoon LL, Korkola JE, Gray JW, Neuwelt EA. Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival. Neurooncol Adv. 2020 Aug 03;2(1):vdaa093. doi: 10.1093/noajnl/vdaa093. eCollection 2020. PMID: 32904984; PMCID: PMC7462280.
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Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses.

Proceedings of the National Academy of Sciences of the United States of America

Burks SR, Kersch CN, Witko JA, Pagel MA, Sundby M, Muldoon LL, Neuwelt EA, Frank JA.
PMID: 33906946
Proc Natl Acad Sci U S A. 2021 May 04;118(18). doi: 10.1073/pnas.2021915118.

Intracarotid arterial hyperosmolar mannitol (ICAHM) blood-brain barrier disruption (BBBD) is effective and safe for delivery of therapeutics for central nervous system malignancies. ICAHM osmotically alters endothelial cells and tight junction integrity to achieve BBBD. However, occurrence of neuroinflammation following...

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Burks SR, Kersch CN, Witko JA, et al. Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses. Proc Natl Acad Sci U S A. 2021;118(18)doi: 10.1073/pnas.2021915118.
Burks, S. R., Kersch, C. N., Witko, J. A., Pagel, M. A., Sundby, M., Muldoon, L. L., Neuwelt, E. A., & Frank, J. A. (2021). Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses. Proceedings of the National Academy of Sciences of the United States of America, 118(18), . https://doi.org/10.1073/pnas.2021915118
Burks, Scott R, et al. "Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses." Proceedings of the National Academy of Sciences of the United States of America vol. 118,18 (2021). doi: https://doi.org/10.1073/pnas.2021915118
Burks SR, Kersch CN, Witko JA, Pagel MA, Sundby M, Muldoon LL, Neuwelt EA, Frank JA. Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses. Proc Natl Acad Sci U S A. 2021 May 04;118(18). doi: 10.1073/pnas.2021915118. PMID: 33906946; PMCID: PMC8106347.
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Diagnosis and management of primary intraocular lymphoma: an update.

Clinical ophthalmology (Auckland, N.Z.)

Jahnke K, Thiel E, Abrey LE, Neuwelt EA, Korfel A.
PMID: 19668478
Clin Ophthalmol. 2007 Sep;1(3):247-58.

Despite recent advances in diagnosis and treatment, the prognosis of primary intraocular lymphoma (PIOL) remains poor, and the optimal treatment has yet to be defined. This review presents an overview of the current status of PIOL with a focus...

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Jahnke K, Thiel E, Abrey LE, et al. Diagnosis and management of primary intraocular lymphoma: an update. Clin Ophthalmol. 2007;1(3):247-58
Jahnke, K., Thiel, E., Abrey, L. E., Neuwelt, E. A., & Korfel, A. (2007). Diagnosis and management of primary intraocular lymphoma: an update. Clinical ophthalmology (Auckland, N.Z.), 1(3), 247-58.
Jahnke, Kristoph, et al. "Diagnosis and management of primary intraocular lymphoma: an update." Clinical ophthalmology (Auckland, N.Z.) vol. 1,3 (2007): 247-58.
Jahnke K, Thiel E, Abrey LE, Neuwelt EA, Korfel A. Diagnosis and management of primary intraocular lymphoma: an update. Clin Ophthalmol. 2007 Sep;1(3):247-58. PMID: 19668478; PMCID: PMC2701132.
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Radiation enhances the delivery of antisense oligonucleotides and improves chemo-radiation efficacy in brain tumor xenografts.

Cancer gene therapy

Ambady P, Wu YJ, Kersch CN, Walker JM, Holland S, Muldoon LL, Neuwelt EA.
PMID: 33850305
Cancer Gene Ther. 2021 Apr 14; doi: 10.1038/s41417-021-00324-6. Epub 2021 Apr 14.

Overexpression of O

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Ambady P, Wu YJ, Kersch CN, et al. Radiation enhances the delivery of antisense oligonucleotides and improves chemo-radiation efficacy in brain tumor xenografts. Cancer Gene Ther. 2021;doi: 10.1038/s41417-021-00324-6.
Ambady, P., Wu, Y. J., Kersch, C. N., Walker, J. M., Holland, S., Muldoon, L. L., & Neuwelt, E. A. (2021). Radiation enhances the delivery of antisense oligonucleotides and improves chemo-radiation efficacy in brain tumor xenografts. Cancer gene therapy, . https://doi.org/10.1038/s41417-021-00324-6
Ambady, Prakash, et al. "Radiation enhances the delivery of antisense oligonucleotides and improves chemo-radiation efficacy in brain tumor xenografts." Cancer gene therapy vol. (2021). doi: https://doi.org/10.1038/s41417-021-00324-6
Ambady P, Wu YJ, Kersch CN, Walker JM, Holland S, Muldoon LL, Neuwelt EA. Radiation enhances the delivery of antisense oligonucleotides and improves chemo-radiation efficacy in brain tumor xenografts. Cancer Gene Ther. 2021 Apr 14; doi: 10.1038/s41417-021-00324-6. Epub 2021 Apr 14. PMID: 33850305.
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Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response.

Journal of neuroinflammation

Todd BP, Chimenti MS, Luo Z, Ferguson PJ, Bassuk AG, Newell EA.
PMID: 34225752
J Neuroinflammation. 2021 Jul 05;18(1):151. doi: 10.1186/s12974-021-02197-w.

BACKGROUND: Traumatic brain injury (TBI) is a leading cause of death and disability that lacks neuroprotective therapies. Following a TBI, secondary injury response pathways are activated and contribute to ongoing neurodegeneration. Microglia and astrocytes are critical neuroimmune modulators with...

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Todd BP, Chimenti MS, Luo Z, et al. Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response. J Neuroinflammation. 2021;18(1):151doi: 10.1186/s12974-021-02197-w.
Todd, B. P., Chimenti, M. S., Luo, Z., Ferguson, P. J., Bassuk, A. G., & Newell, E. A. (2021). Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response. Journal of neuroinflammation, 18(1), 151. https://doi.org/10.1186/s12974-021-02197-w
Todd, Brittany P, et al. "Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response." Journal of neuroinflammation vol. 18,1 (2021): 151. doi: https://doi.org/10.1186/s12974-021-02197-w
Todd BP, Chimenti MS, Luo Z, Ferguson PJ, Bassuk AG, Newell EA. Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response. J Neuroinflammation. 2021 Jul 05;18(1):151. doi: 10.1186/s12974-021-02197-w. PMID: 34225752; PMCID: PMC8259035.
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Educating public health physicians for the future: a current perspective from Aotearoa New Zealand.

Australia and New Zealand health policy

Bullen C, Neuwelt P.
PMID: 19358712
Aust New Zealand Health Policy. 2009 Apr 09;6:7. doi: 10.1186/1743-8462-6-7.

Persisting, and in some cases widening, inequalities in health within and between countries present significant challenges to the focus and practice of contemporary public health, and by association, to public health education. As public health physicians and academic educators...

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Bullen C, Neuwelt P. Educating public health physicians for the future: a current perspective from Aotearoa New Zealand. Aust New Zealand Health Policy. 2009;6:7doi: 10.1186/1743-8462-6-7.
Bullen, C., & Neuwelt, P. (2009). Educating public health physicians for the future: a current perspective from Aotearoa New Zealand. Australia and New Zealand health policy, 67. https://doi.org/10.1186/1743-8462-6-7
Bullen, Chris, and Neuwelt, Pat. "Educating public health physicians for the future: a current perspective from Aotearoa New Zealand." Australia and New Zealand health policy vol. 6 (2009): 7. doi: https://doi.org/10.1186/1743-8462-6-7
Bullen C, Neuwelt P. Educating public health physicians for the future: a current perspective from Aotearoa New Zealand. Aust New Zealand Health Policy. 2009 Apr 09;6:7. doi: 10.1186/1743-8462-6-7. PMID: 19358712; PMCID: PMC2672091.
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Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation.

Translational stroke research

Hasan DM, Amans M, Tihan T, Hess C, Guo Y, Cha S, Su H, Martin AJ, Lawton MT, Neuwelt EA, Saloner DA, Young WL.
PMID: 23002401
Transl Stroke Res. 2012 Jul;3:166-73. doi: 10.1007/s12975-012-0172-y.

Inflammation cell infiltration and cytokine expression are seen in the vascular walls and intervening stroma of resected brain arteriovenous malformation (bAVM) specimens, even in unruptured and previously untreated lesions. Macrophages may play a critical role in bAVM progression to...

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Hasan DM, Amans M, Tihan T, et al. Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation. Transl Stroke Res. 2012;3:166-73doi: 10.1007/s12975-012-0172-y.
Hasan, D. M., Amans, M., Tihan, T., Hess, C., Guo, Y., Cha, S., Su, H., Martin, A. J., Lawton, M. T., Neuwelt, E. A., Saloner, D. A., & Young, W. L. (2012). Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation. Translational stroke research, 3166-73. https://doi.org/10.1007/s12975-012-0172-y
Hasan, David M, et al. "Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation." Translational stroke research vol. 3 (2012): 166-73. doi: https://doi.org/10.1007/s12975-012-0172-y
Hasan DM, Amans M, Tihan T, Hess C, Guo Y, Cha S, Su H, Martin AJ, Lawton MT, Neuwelt EA, Saloner DA, Young WL. Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation. Transl Stroke Res. 2012 Jul;3:166-73. doi: 10.1007/s12975-012-0172-y. PMID: 23002401; PMCID: PMC3445332.
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Primary dystonia misinterpreted as Parkinson disease: Video case presentation and practical clues.

Neurology. Clinical practice

Klepitskaya O, Neuwelt AJ, Nguyen T, Leehey M.
PMID: 24353921
Neurol Clin Pract. 2013 Dec;3(6):469-474. doi: 10.1212/CPJ.0b013e3182a78eb5.

Diagnosing dystonia can be challenging and depends on the recognition of subtle clinical signs. Due to clinical heterogeneity, variable age at presentation, and overlapping features with other disorders, dystonia is under-recognized. The presence of dystonic tremor is often a...

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Klepitskaya O, Neuwelt AJ, Nguyen T, et al. Primary dystonia misinterpreted as Parkinson disease: Video case presentation and practical clues. Neurol Clin Pract. 2013;3(6):469-474doi: 10.1212/CPJ.0b013e3182a78eb5.
Klepitskaya, O., Neuwelt, A. J., Nguyen, T., & Leehey, M. (2013). Primary dystonia misinterpreted as Parkinson disease: Video case presentation and practical clues. Neurology. Clinical practice, 3(6), 469-474. https://doi.org/10.1212/CPJ.0b013e3182a78eb5
Klepitskaya, Olga, et al. "Primary dystonia misinterpreted as Parkinson disease: Video case presentation and practical clues." Neurology. Clinical practice vol. 3,6 (2013): 469-474. doi: https://doi.org/10.1212/CPJ.0b013e3182a78eb5
Klepitskaya O, Neuwelt AJ, Nguyen T, Leehey M. Primary dystonia misinterpreted as Parkinson disease: Video case presentation and practical clues. Neurol Clin Pract. 2013 Dec;3(6):469-474. doi: 10.1212/CPJ.0b013e3182a78eb5. PMID: 24353921; PMCID: PMC3863978.
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Showing 1 to 12 of 17 entries