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Showing 1 to 12 of 38 entries
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Natural Killer cell control of .

Oncoimmunology

de Andrade LF, Ngiow SF, Martinet L, Smyth MJ.
PMID: 26137412
Oncoimmunology. 2015 Apr 01;4(4):e998119. doi: 10.1080/2162402X.2014.998119. eCollection 2015 Apr.

Pharmacologic inhibition of the mutant BRAF

Novel Genetic Variants of Hepatitis B Virus in Fulminant Hepatitis.

Journal of pathogens

Chook JB, Ngeow YF, Tee KK, Peh SC, Mohamed R, Golightly YM.
PMID: 29410920
J Pathog. 2017;2017:1231204. doi: 10.1155/2017/1231204. Epub 2017 Dec 19.

Fulminant hepatitis (FH) is a life-threatening liver disease characterised by intense immune attack and massive liver cell death. The common precore stop codon mutation of hepatitis B virus (HBV), A1896, is frequently associated with FH, but lacks specificity. This...

A simple spreadsheet-based method for relative quantification using quantitative real-time PCR.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

Ng HF, Ngeow YF.
PMID: 34854201
Biochem Mol Biol Educ. 2021 Dec 02; doi: 10.1002/bmb.21596. Epub 2021 Dec 02.

Relative quantification is a popular analysis in gene expression studies using quantitative real-time PCR (qPCR). However, the calculation steps using the major algorithms for this analysis are rather complicated. In this study, we developed an easy-to-use spreadsheet-based method for...

Diabetic Autonomic Neuropathy.

The Medical journal of Malaysia

Ngeow TF.
PMID: 35008154
Med J Malaysia. 1976 Dec;31(2):115-119.

No abstract available.

Genomic diversity of SARS-CoV-2 in Malaysia.

PeerJ

Mohamad Noordin N, Tan JL, Chong CK, Chem YK, Tajudin N, Abu Bakar RS, Sengol S, Phoon HYP, Che Azid NAM, W Mohd Arifin WNA, Aziz ZA, Hussin H, Ibrahim NS, Omar A, Ravi U, Kamarul Zaman KH, Yamin MA, Ngeow YF.
PMID: 34760404
PeerJ. 2021 Nov 03;9:e12449. doi: 10.7717/peerj.12449. eCollection 2021.

BACKGROUND: More than a year after its first appearance in December 2019, the COVID-19 pandemic is still on a rampage in many parts of the world. Although several vaccines have been approved for emergency use, the emergence and rapid...

NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy.

The Journal of experimental medicine

Lewis EL, Xu R, Beltra JC, Ngiow SF, Cohen J, Telange R, Crane A, Sawinski D, Wherry EJ, Porrett PM.
PMID: 34882194
J Exp Med. 2022 Jan 03;219(1). doi: 10.1084/jem.20201599. Epub 2021 Dec 09.

Pregnancy is a common immunization event, but the molecular mechanisms and immunological consequences provoked by pregnancy remain largely unknown. We used mouse models and human transplant registry data to reveal that pregnancy induced exhausted CD8 T cells (Preg-TEX), which...

Genomic Comparisons Reveal Microevolutionary Differences in .

Frontiers in microbiology

Tan JL, Ng KP, Ong CS, Ngeow YF.
PMID: 29109707
Front Microbiol. 2017 Oct 23;8:2042. doi: 10.3389/fmicb.2017.02042. eCollection 2017.

No abstract available.

Chromosomal rearrangements and protein globularity changes in Mycobacterium tuberculosis isolates from cerebrospinal fluid.

PeerJ

Saw SH, Tan JL, Chan XY, Chan KG, Ngeow YF.
PMID: 27688977
PeerJ. 2016 Sep 21;4:e2484. doi: 10.7717/peerj.2484. eCollection 2016.

BACKGROUND: Meningitis is a major cause of mortality in tuberculosis (TB). It is not clear what factors promote central nervous system invasion and pathology but it has been reported that certain strains of Mycobacterium tuberculosis (Mtb) might have genetic...

BRAF-targeted therapy and immune responses to melanoma.

Oncoimmunology

Ngiow SF, Knight DA, Ribas A, McArthur GA, Smyth MJ.
PMID: 23894707
Oncoimmunology. 2013 Jun 01;2(6):e24462. doi: 10.4161/onci.24462. Epub 2013 May 09.

Type I BRAF inhibitors and immunotherapy constitute two new exciting approaches for the treatment of advanced malignant melanoma. We have recently elucidated a role for host C-C chemokine receptor type 2 (CCR2) in the antineoplastic effects of type I...

Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Malaysia.

Genome announcements

Ng KP, Yew SM, Chan CL, Chong J, Tang SN, Soo-Hoo TS, Na SL, Hassan H, Ngeow YF, Hoh CC, Lee KW, Yee WY.
PMID: 23405310
Genome Announc. 2013 Jan;1(1). doi: 10.1128/genomeA.00056-12. Epub 2013 Jan 24.

The emergence of the global threat of extensively drug-resistant (XDR) Mycobacterium tuberculosis reveals weaknesses in tuberculosis management and diagnostic services. We report the draft genome sequence of the first extensively drug-resistant Mycobacterium tuberculosis strain isolated in Malaysia. The sequence...

Draft Genome Sequence of a Clinical Isolate of Mycobacterium tuberculosis Strain PR05.

Genome announcements

Ismail A, Teh LK, Ngeow YF, Norazmi MN, Zainul ZF, Tang TH, Najimudin N, Salleh MZ.
PMID: 23788553
Genome Announc. 2013 Jun 20;1(3). doi: 10.1128/genomeA.00397-13.

We report the annotated genome sequence of a clinical isolate, Mycobacterium tuberculosis strain PR05, which was isolated from the human cerebrospinal fluid of a patient diagnosed with tuberculosis.

Immunosurveillance and therapy of multiple myeloma are CD226 dependent.

The Journal of clinical investigation

Guillerey C, Ferrari de Andrade L, Vuckovic S, Miles K, Ngiow SF, Yong MC, Teng MW, Colonna M, Ritchie DS, Chesi M, Bergsagel PL, Hill GR, Smyth MJ, Martinet L.
PMID: 26075821
J Clin Invest. 2015 Jul 01;125(7):2904. doi: 10.1172/JCI82646. Epub 2015 Jun 15.

No abstract available.

Showing 1 to 12 of 38 entries