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Showing 1 to 12 of 13 entries
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Empowering newborn screening programs in African countries through establishment of an international collaborative effort.

Journal of community genetics

Therrell BL, Lloyd-Puryear MA, Ohene-Frempong K, Ware RE, Padilla CD, Ambrose EE, Barkat A, Ghazal H, Kiyaga C, Mvalo T, Nnodu O, Ouldim K, Rahimy MC, Santos B, Tshilolo L, Yusuf C, Zarbalian G, Watson MS.
PMID: 32415570
J Community Genet. 2020 Jul;11(3):253-268. doi: 10.1007/s12687-020-00463-7. Epub 2020 May 15.

In an effort to explore new knowledge and to develop meaningful collaborations for improving child health, the First Pan African Workshop on Newborn Screening was convened in June 2019 in Rabat, Morocco. Participants included an informal network of newborn...

Effect of amlodipine, a calcium channel antagonist, on gonadal steroid of male Wistar albino rats.

Journal of experimental pharmacology

Onwuka FC, Wuanyanwu KP, Nnodu CK, Erhabor O.
PMID: 27186091
J Exp Pharmacol. 2010 Mar 13;2:55-8. eCollection 2010.

This study was carried out to investigate the effect of prolonged intake of calcium-channel blocker amlodipine, an antihypertensive drug on gonadal steroid hormone (testosterone) of male albino rats. Three different concentrations of amlodipine (0.01, 0.02 and 0.03 mg/kg body...

Implementation science research for the scale-up of evidence-based interventions for sickle cell disease in africa: a commentary.

Globalization and health

Gyamfi J, Ojo T, Iwelunmor J, Ogedegbe G, Ryan N, Diawara A, Nnodu O, Wonkam A, Royal C, Peprah E.
PMID: 33596947
Global Health. 2021 Feb 17;17(1):20. doi: 10.1186/s12992-021-00671-x.

BACKGROUND: The burden of sickle cell disease (SCD) is greatest among African nations. Effective scalability of evidence-based interventions (e.g., newborn screening, health education, prophylaxis for infection, optimal nutrition and hydration, hydroxyurea therapy, blood transfusions, and transcranial Doppler (TCD) screening)...

Utilization of Pneumococcal Vaccine and Penicillin Prophylaxis in Sickle Cell Disease in Three African Countries: Assessment among Healthcare Providers in SickleInAfrica.

Hemoglobin

Brown BJ, Madu A, Sangeda RZ, Nkya S, Peprah E, Paintsil V, Mmbando BP, Gyamfi J, Okocha CE, Asala SA, Nembaware V, Jonas M, Kengne AP, Chimusa ER, Nguweneza A, Isa HA, Nnebe-Agumadu U, Adekile AD, Osei-Akoto A, Ohene-Frempong K, Balandya E, Nnodu OE, Wonkam A, Makani J.
PMID: 34355623
Hemoglobin. 2021 May;45(3):163-170. doi: 10.1080/03630269.2021.1954943. Epub 2021 Aug 06.

Sickle cell disease is a genetic disease with a predisposition to infections caused by encapsulated organisms, especially

White Paper: Pathways to Progress in Newborn Screening for Sickle Cell Disease in Sub-Saharan Africa.

Journal of tropical diseases & public health

Hsu L, Nnodu OE, Brown BJ, Tluway F, King S, Dogara LG, Patil C, Shevkoplyas SS, Lettre G, Cooper RS, Gordeuk VR, Tayo BO.
PMID: 30505949
J Trop Dis Public Health. 2018;6(2):260. doi: 10.4172/2329-891X.1000260. Epub 2018 Jul 10.

Sickle Cell Disease (SCD) is among the most common single-gene diseases in the world but evidence-based comprehensive health care has not been implemented where the highest prevalence of SCD occurs, in sub-Saharan Africa (SSA). It represents an urgent health...

Proceedings of a Sickle Cell Disease Ontology workshop - Towards the first comprehensive ontology for Sickle Cell Disease.

Applied & translational genomics

Mulder N, Nembaware V, Adekile A, Anie KA, Inusa B, Brown B, Campbell A, Chinenere F, Chunda-Liyoka C, Derebail VK, Geard A, Ghedira K, Hamilton CM, Hanchard NA, Haendel M, Huggins W, Ibrahim M, Jupp S, Kamga KK, Knight-Madden J, Lopez-Sall P, Mbiyavanga M, Munube D, Nirenberg D, Nnodu O, Ofori-Acquah SF, Ohene-Frempong K, Opap KB, Panji S, Park M, Pule G, Royal C, Sangeda R, Tayo B, Treadwell M, Tshilolo L, Wonkam A.
PMID: 27354937
Appl Transl Genom. 2016 Mar 15;9:23-9. doi: 10.1016/j.atg.2016.03.005. eCollection 2016 Jun.

Sickle cell disease (SCD) is a debilitating single gene disorder caused by a single point mutation that results in physical deformation (i.e. sickling) of erythrocytes at reduced oxygen tensions. Up to 75% of SCD in newborns world-wide occurs in...

Blinding bilateral hyperviscosity retinopathy in a 43-year-old nigerian male with lymphoplasmacytic lymphoma: a case report and management challenges.

Case reports in oncological medicine

Ayanniyi AA, Ejikeme UG, Tanko Y, Muhammad RC, Nnodu OE.
PMID: 24883217
Case Rep Oncol Med. 2014;2014:567632. doi: 10.1155/2014/567632. Epub 2014 May 05.

Lymphoplasmacytic lymphomas are rare and may present with uncommon and devastating symptoms. We report a case of a 43-year-old male who presented with bleeding gums and sudden onset of bilateral blindness but was not on anticoagulants and had no...

Establishing a Multi-Country Sickle Cell Disease Registry in Africa: Ethical Considerations.

Frontiers in genetics

Munung NS, Nembaware V, de Vries J, Bukini D, Tluway F, Treadwell M, Sangeda RZ, Mazandu G, Jonas M, Paintsil V, Nnodu OE, Balandya E, Makani J, Wonkam A.
PMID: 31649726
Front Genet. 2019 Oct 10;10:943. doi: 10.3389/fgene.2019.00943. eCollection 2019.

Sickle cell disease (SCD) is one of the most prevalent genetic conditions in sub-Saharan Africa. It is a chronic, lifelong disease often characterized by severe pain. However, SCD has received little investment terms of health research, though there is...

Corrigendum to "Sickle cell disease clinical phenotypes in Nigeria: A preliminary analysis of the Sickle Pan Africa Research Consortium Nigeria database" [Blood Cells, Molecules and Diseases (2020) Start page-End page/202438].

Blood cells, molecules & diseases

Isa H, Adegoke S, Madu A, Hassan AA, Ohiaeri C, Chianumba R, Brown B, Okocha E, Ugwu N, Diaku-Akinwumi I, Adeyemo T, Kuliya-Gwarzo A, Dogara L, Lawal H, Tanko Y, Ladu A, Kangiwa U, Ekwem L, Oniyangi S, Wakama T, Umoru D, Olanrewaju O, Akinola N, Nnebe-Agumadu U, Asala S, Adekile A, Olaniyi J, Sangeda R, Nnodu O.
PMID: 32739321
Blood Cells Mol Dis. 2021 May;88:102480. doi: 10.1016/j.bcmd.2020.102480. Epub 2020 Jul 29.

No abstract available.

A Multi-centre Survey of Acceptability of Newborn Screening for Sickle Cell Disease in Nigeria.

Cureus

Nnodu OE, Adegoke SA, Ezenwosu OU, Emodi II, Ugwu NI, Ohiaeri CN, Brown BJ, Olaniyi JA, Isa H, Okeke CC, Bene BA, Balogun MT, Okocha EC, Aneke JC, Lawson JOJ, Usman AM, Diaku-Akinwumi IN, Okolo AA, Israel-Aina YT, Jamda M, Aworanti OW, Piel FB, Adekile AD.
PMID: 32181059
Cureus. 2018 Mar 21;10(3):e2354. doi: 10.7759/cureus.2354.

Background Sickle cell disease (SCD) is a major genetic disease that manifests early in life and may lead to significant morbidities. One of the health care services that have been effective in reducing the burden of SCD in developed...

Fine needle aspiration cytology of bone tumours--the experience from the National Orthopaedic and Lagos University Teaching Hospitals, Lagos, Nigeria.

CytoJournal

Nnodu OE, Giwa SO, Eyesan SU, Abdulkareem FB.
PMID: 16776844
Cytojournal. 2006 Jun 15;3:16. doi: 10.1186/1742-6413-3-16.

BACKGROUND: Due to difficulty in confirming clinical suspicions of malignancy in patients presenting with bone tumours, the cost of surgical biopsies where hospital charges are borne almost entirely by patients, competition with bone setters and healing homes with high...

A Randomized Trial Comparing the Efficacy of Methylene Blue Dye Alone Versus Combination of Methylene Blue Dye and Radioactive Sulfur Colloid in Sentinel Lymph Node Biopsy for Early Stage Breast Cancer Patients.

Indian journal of surgical oncology

Gupta V, Raju K, Rao TS, Naidu CK, Goel V, Hariharan N, Nagarajuch R, Madhunarayana B, Wollowski M, Brown L, Goel A.
PMID: 32523266
Indian J Surg Oncol. 2020 Jun;11(2):216-222. doi: 10.1007/s13193-019-01023-3. Epub 2019 Dec 10.

Although sentinel lymph node biopsy (SLNB) has become a standard of care for management of axilla in breast cancer patients, the technique of SLNB is still not well defined. Unlike radioactive sulfur colloid which requires nuclear medicine facilities, methylene...

Showing 1 to 12 of 13 entries