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Showing 1 to 12 of 77 entries
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Role of Protein Glycosylation in Candida parapsilosis Cell Wall Integrity and Host Interaction.

Frontiers in microbiology

Pérez-García LA, Csonka K, Flores-Carreón A, Estrada-Mata E, Mellado-Mojica E, Németh T, López-Ramírez LA, Toth R, López MG, Vizler C, Marton A, Tóth A, Nosanchuk JD, Gácser A, Mora-Montes HM.
PMID: 27014229
Front Microbiol. 2016 Mar 08;7:306. doi: 10.3389/fmicb.2016.00306. eCollection 2016.

Candida parapsilosis is an important, emerging opportunistic fungal pathogen. Highly mannosylated fungal cell wall proteins are initial contact points with host immune systems. In Candida albicans, Och1 is a Golgi α1,6-mannosyltransferase that plays a key role in the elaboration...

Butyricimonas virosa bacteraemia and bowel disease: case report and review.

New microbes and new infections

Enemchukwu CU, Ben-Faras H, Gialanella P, Szymczak WA, Nosanchuk JD, Madaline TF.
PMID: 27408738
New Microbes New Infect. 2016 May 14;13:34-6. doi: 10.1016/j.nmni.2016.05.004. eCollection 2016 Sep.

Only two cases of human infection with the anaerobic Gram-negative bacillus Butyricimonas virosa have been previously reported. We describe the case of a 69-year-old man with B. virosa and diverticulitis, further supporting an association of bacteraemia with this pathogen...

Fungal Melanin: What do We Know About Structure?.

Frontiers in microbiology

Nosanchuk JD, Stark RE, Casadevall A.
PMID: 26733993
Front Microbiol. 2015 Dec 22;6:1463. doi: 10.3389/fmicb.2015.01463. eCollection 2015.

The production of melanin significantly enhances the virulence of many important human pathogenic fungi. Despite fungal melanin's importance in human disease, as well as melanin's contribution to the ability of fungi to survive in diverse hostile environments, the structure...

Evaluation of an enzyme-linked immunosorbent assay using purified, deglycosylated histoplasmin for different clinical manifestations of histoplasmosis.

Microbiology research

Guimarães AJ, Pizzini CV, De Abreu Almeida M, Peralta JM, Nosanchuk JD, Zancopé-Oliveira RM.
PMID: 21691458
Microbiol Res (Pavia). 2010;1(1). doi: 10.4081/mr.2010.e2. Epub 2010 Mar 17.

Diagnosis of invasive fungal diseases remains problematic, especially in undeveloped countries. We have developed an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to

DIAGNOSIS OF HISTOPLASMOSIS.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]

Guimarães AJ, Nosanchuk JD, Zancopé-Oliveira RM.
PMID: 20445761
Braz J Microbiol. 2006 Jan;37(1):1-13. doi: 10.1590/S1517-83822006000100001.

Endemic mycoses can be challenging to diagnose and accurate interpretation of laboratory data is important to ensure the most appropriate treatment for the patients. Although the definitive diagnosis of histoplasmosis (HP), one of the most frequent endemic mycoses in...

Biogenesis of extracellular vesicles in yeast: Many questions with few answers.

Communicative & integrative biology

Oliveira DL, Nakayasu ES, Joffe LS, Guimarães AJ, Sobreira TJ, Nosanchuk JD, Cordero RJ, Frases S, Casadevall A, Almeida IC, Nimrichter L, Rodrigues ML.
PMID: 21331232
Commun Integr Biol. 2010 Nov;3(6):533-5. doi: 10.4161/cib.3.6.12756. Epub 2010 Nov 01.

The cellular events required for unconventional protein secretion in eukaryotic pathogens are beginning to be revealed. In fungi, extracellular release of proteins involves passage through the cell wall by mechanisms that are poorly understood. In recent years, several studies...

Developing Interactive Antimicrobial Stewardship and Infection Prevention Curricula for Diverse Learners: A Tailored Approach.

Open forum infectious diseases

Nori P, Madaline T, Munjal I, Bhar S, Guo Y, Seo SK, Porrovecchio A, Gancher E, Nosanchuk J, Pirofski LA, Ostrowsky B.
PMID: 28748196
Open Forum Infect Dis. 2017 Jul 20;4(3):ofx117. doi: 10.1093/ofid/ofx117. eCollection 2017.

BACKGROUND: To impart principles of antimicrobial stewardship (AS) and infection prevention and control (IPC), we developed a curriculum tailored to the diverse aptitudes of learners at our medical center.METHODS: We integrated case-based modules, group learning activities, smartphone applications (apps),...

Fidgetin-Like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing.

Advances in wound care

O'Rourke BP, Kramer AH, Cao LL, Inayathullah M, Guzik H, Rajadas J, Nosanchuk JD, Sharp DJ.
PMID: 30911440
Adv Wound Care (New Rochelle). 2019 Mar 01;8(3):91-100. doi: 10.1089/wound.2018.0827. Epub 2019 Mar 05.

Microtubules (MTs) are intracellular polymers that provide structure to the cell, serve as railways for intracellular transport, and regulate many cellular activities, including cell migration. The dynamicity and function of the MT cytoskeleton are determined in large part by...

Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody.

Frontiers in microbiology

Helal M, Allen KJH, van Dijk B, Nosanchuk JD, Snead E, Dadachova E.
PMID: 32117166
Front Microbiol. 2020 Feb 07;11:147. doi: 10.3389/fmicb.2020.00147. eCollection 2020.

Invasive fungal infections (IFI) cause devastating morbidity and mortality, with the number of IFIs more than tripling since 1979. Our laboratories were the first to demonstrate that radiolabeled microorganism-specific monoclonal antibodies are highly effective for treatment of experimental fungal,...

A .

Journal of fungi (Basel, Switzerland)

Pál SE, Tóth R, Nosanchuk JD, Vágvölgyi C, Németh T, Gácser A.
PMID: 33572958
J Fungi (Basel). 2021 Jan 29;7(2). doi: 10.3390/jof7020097.

Relative to the vast data regarding the virulence mechanisms of

Transcriptional and translational landscape of .

Computational and structural biotechnology journal

Zamith-Miranda D, Amatuzzi RF, Munhoz da Rocha IF, Martins ST, Lucena ACR, Vieira AZ, Trentin G, Almeida F, Rodrigues ML, Nakayasu ES, Nosanchuk JD, Alves LR.
PMID: 34630944
Comput Struct Biotechnol J. 2021 Sep 14;19:5264-5277. doi: 10.1016/j.csbj.2021.09.007. eCollection 2021.

No abstract available.

Cytokine and Chemokine Responses in Invasive Aspergillosis Following Hematopoietic Stem Cell Transplantation: Past Evidence for Future Therapy of Aspergillosis.

Journal of fungi (Basel, Switzerland)

Thammasit P, Sripetchwandee J, Nosanchuk JD, Chattipakorn SC, Chattipakorn N, Youngchim S.
PMID: 34575791
J Fungi (Basel). 2021 Sep 13;7(9). doi: 10.3390/jof7090753.

Invasive pulmonary aspergillosis is a frequent complication in immunocompromised individuals, and it continues to be an important cause of mortality in patients undergoing hematopoietic stem cell transplantation. In addition to antifungal therapy used for mycoses, immune-modulatory molecules such as...

Showing 1 to 12 of 77 entries