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Showing 1 to 12 of 104 entries
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DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

NPJ breast cancer

Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O, van 't Veer L.
PMID: 28948212
NPJ Breast Cancer. 2017 Aug 25;3:31. doi: 10.1038/s41523-017-0025-7. eCollection 2017.

Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature. However, not all triple negative patients achieved pathologic complete response...

Incorporating a Psychological Counselor in a Cancer Risk Assessment Program: Necessity, Acceptability, and Potential Roles.

Journal of genetic counseling

Matthews AK, Brandenburg DL, Cummings S, Olopade OI.
PMID: 26141561
J Genet Couns. 2002 Feb;11(1):51-64. doi: 10.1023/A:1013820515603.

Evidence suggests that cancer risk assessment may be associated with increased psychological distress. This exploratory study assessed the necessity and acceptability of incorporating psychological counseling into routine clinic procedures at a cancer risk program. Following a visit to a...

Metabolic profiles of triple-negative and luminal A breast cancer subtypes in African-American identify key metabolic differences.

Oncotarget

Tayyari F, Gowda GAN, Olopade OF, Berg R, Yang HH, Lee MP, Ngwa WF, Mittal SK, Raftery D, Mohammed SI.
PMID: 29545929
Oncotarget. 2018 Feb 07;9(14):11677-11690. doi: 10.18632/oncotarget.24433. eCollection 2018 Feb 20.

Breast cancer, a heterogeneous disease with variable pathophysiology and biology, is classified into four major subtypes. While hormonal- and antibody-targeted therapies are effective in the patients with luminal and HER-2 subtypes, the patients with triple-negative breast cancer (TNBC) subtype...

Morphometric studies of the mandibular and maxillofacial regions of the Kuri cattle and the implications in regional anaesthesia.

Folia morphologica

Gambo BG, Yahaya A, Girgiri I, Olopade JO.
PMID: 26050804
Folia Morphol (Warsz). 2015;74(2):183-7. doi: 10.5603/FM.2015.0029.

This work investigated and analysed some morphometrical measurements of mandibles and maxillofacial regions of ten adult Kuri cattle (above 5 years) skulls that were apparently free from musculoskeletal deformity. A total of 19 (13 mandibular and 6 maxillofacial) parameters...

Establishment of a standing ethics/institutional review board in a nigerian university: a blueprint for developing countries.

Journal of empirical research on human research ethics : JERHRE

Falusi AG, Olopade OI, Olopade CO.
PMID: 19385889
J Empir Res Hum Res Ethics. 2007 Mar;2(1):21-30. doi: 10.1525/jer.2007.2.1.21.

AN ETHICS/INSTITUTIONAL REVIEW BOARD (IRB) was established according to International standards at the University of Ibadan in Nigeria. To achieve this, a private-public partnership was developed to support a review of prevailing practice and the development of necessary infrastructure...

Towards an Oncology Database (ONCOD) Using a Warehousing Approach.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Wang X, Liu L, Fackenthal J, Chang P, Newstead G, Chmura S, Foster I, Olopade OI.
PMID: 22779060
AMIA Jt Summits Transl Sci Proc. 2012;2012:105. Epub 2012 Mar 19.

Here we report a model data mart developed upon a warehousing system focusing on oncology data to explore optimized system architecture to support enhanced data integration and application capacity.

Pilot Survey of Breast Cancer Management in Sub-Saharan Africa.

Journal of global oncology

Vanderpuye VDNK, Olopade OI, Huo D.
PMID: 28717760
J Glob Oncol. 2016 Dec 21;3(3):194-200. doi: 10.1200/JGO.2016.004945. eCollection 2017 Jun.

PURPOSE: To understand the current state of breast cancer management in sub-Saharan Africa.METHODS: We conducted an anonymous online survey of breast cancer management among African Organization for Research and Treatment in Cancer (AORTIC) members by using a 42-question structured...

Virome Assembly and Annotation: A Surprise in the Namib Desert.

Frontiers in microbiology

Hesse U, van Heusden P, Kirby BM, Olonade I, van Zyl LJ, Trindade M.
PMID: 28167933
Front Microbiol. 2017 Jan 23;8:13. doi: 10.3389/fmicb.2017.00013. eCollection 2017.

Sequencing, assembly, and annotation of environmental virome samples is challenging. Methodological biases and differences in species abundance result in fragmentary read coverage; sequence reconstruction is further complicated by the mosaic nature of viral genomes. In this paper, we focus...

LXR/RXR pathway signaling associated with triple-negative breast cancer in African American women.

Breast cancer (Dove Medical Press)

Torres-Luquis O, Madden K, N'dri NM, Berg R, Olopade OF, Ngwa W, Abuidris D, Mittal S, Lyn-Cook B, Mohammed SI.
PMID: 30588086
Breast Cancer (Dove Med Press). 2018 Dec 20;11:1-12. doi: 10.2147/BCTT.S185960. eCollection 2019.

BACKGROUND: Triple-negative breast cancer (TNBC) is more prevalent in African and African American (AA) women compared to European American (EA) women. African and AA women diagnosed with TNBC experience high frequencies of metastases and less favorable outcomes. Emerging evidence...

Knowledge and Attitudes about Breast Cancer among Women: A Wake-Up Call in Nigeria.

Open access Macedonian journal of medical sciences

George TO, Allo TA, Amoo EO, Olonade O.
PMID: 31210826
Open Access Maced J Med Sci. 2019 May 25;7(10):1700-1705. doi: 10.3889/oamjms.2019.221. eCollection 2019 May 31.

BACKGROUND: Preventable deaths resulting from the scourge of breast cancer has become alarming and worrisome in many societies in developing countries, including Nigeria. Of much concern is the fact that breast cancer has continued to claim the precious lives...

INTESTINAL PARASITES, NUTRITIONAL STATUS AND COGNITIVE FUNCTION AMONG PRIMARY SCHOOL PUPILS IN ILE-IFE, OSUN STATE, NIGERIA.

African journal of infectious diseases

Olopade BO, Idowu CO, Oyelese AO, Aboderin AO.
PMID: 30109282
Afr J Infect Dis. 2018 Jun 18;12(2):21-28. doi: 10.21010/ajid.v12i2.4. eCollection 2018.

BACKGROUND: Intestinal parasites are a cause of morbidity and mortality throughout the world particularly in developing countries and they are common health problems of children. This study determined the prevalence of intestinal parasites among primary school children, assessed risk...

Understanding gender issues in Nigeria: the imperative for sustainable development.

Heliyon

Olonade OY, Oyibode BO, Idowu BO, George TO, Iwelumor OS, Ozoya MI, Egharevba ME, Adetunde CO.
PMID: 34377858
Heliyon. 2021 Jul 18;7(7):e07622. doi: 10.1016/j.heliyon.2021.e07622. eCollection 2021 Jul.

Whenever the term "Gender" is mentioned, many readily attribute it to the womenfolk who, in many societies, are challenged and often put in a disadvantaged position concerning the men. As a result, many women empowerment programs are being championed...

Showing 1 to 12 of 104 entries