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Showing 1 to 12 of 115 entries
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Joint Analysis of Survival Time and Longitudinal Categorical Outcomes.

Statistics in biosciences

Choi J, Cai J, Zeng D, Olshan AF.
PMID: 26052353
Stat Biosci. 2015 May;7(1):19-47. doi: 10.1007/s12561-013-9091-z.

In biomedical or public health research, it is common for both survival time and longitudinal categorical outcomes to be collected for a subject, along with the subject's characteristics or risk factors. Investigators are often interested in finding important variables...

Kidney stone formation and antioxidant effects of .

Avicenna journal of phytomedicine

Golshan A, Hayatdavoudi P, Hadjzadeh MA, Khajavi Rad A, Mohamadian Roshan N, Abbasnezhad A, Mousavi SM, Pakdel R, Zarei B, Aghaee A.
PMID: 28348973
Avicenna J Phytomed. 2017 Mar-Apr;7(2):180-190.

OBJECTIVES: The antioxidant capacity impairs in kidney and urinary bladder of animals with stone disease. Herbal medicine can improve the antioxidant condition of renal tissue. MATERIALS AND METHODS: Fifty male Wistar rats were randomly divided into 5 experimental groups...

The case-only independence assumption: associations between genetic polymorphisms and smoking among controls in two population-based studies.

International journal of molecular epidemiology and genetics

Hodgson ME, Olshan AF, North KE, Poole CL, Zeng D, Tse CK, Keku TO, Galanko J, Sandler R, Millikan RC.
PMID: 23205185
Int J Mol Epidemiol Genet. 2012;3(4):333-60. Epub 2012 Nov 15.

The independence assumption for a case-only analysis of statistical interaction, i. e. that genetic (G) and environmental exposures (E) are not associated in the source population, is often checked in surrogate populations. Few studies have examined G-E association in...

Children's Oncology Group's 2013 blueprint for research: epidemiology.

Pediatric blood & cancer

Spector LG, Ross JA, Olshan AF.
PMID: 23255344
Pediatr Blood Cancer. 2013 Jun;60(6):1059-62. doi: 10.1002/pbc.24434. Epub 2012 Dec 19.

Investigators worldwide have for over 40 years conducted case-control studies aimed at determining the causes of childhood cancer. The central challenge to conducting such research is the rarity of childhood cancer, thus many studies aggregate cases through clinical trials...

The reduction of rotational ambiguity in soft-modeling by introducing hard models.

Analytica chimica acta

Golshan A, Abdollahi H, Maeder M.
PMID: 22122928
Anal Chim Acta. 2012 Jan 04;709:32-40. doi: 10.1016/j.aca.2011.10.057. Epub 2011 Nov 07.

Rotational ambiguity is a major problem in the application of soft-modeling analysis to a variety of multivariate mixture resolution problems and particularly important in the analysis of kinetic data. Soft-modeling analyses rely on constraints that restrict the concentration profiles...

Next-Generation Sequencing of Uveal Melanoma for Detection of Genetic Alterations Predicting Metastasis.

Translational vision science & technology

Afshar AR, Damato BE, Stewart JM, Zablotska LB, Roy R, Olshen AB, Joseph NM, Bastian BC.
PMID: 31024753
Transl Vis Sci Technol. 2019 Apr 17;8(2):18. doi: 10.1167/tvst.8.2.18. eCollection 2019 Mar.

PURPOSE: To clinically use the UCSF500, a pancancer, next-generation sequencing assay in uveal melanoma (UM) and to correlate results with gene expression profiling (GEP) and predictive factors for metastasis.METHODS: Cohort study. Tumor samples of adult UM patients were analyzed...

Experimental observation and investigation of energy exchange between an electron beam and counterpropagating laser beams in a Compton-scattering free-electron-laser scheme.

Physical review. A, General physics

Friedman A, Gover A, Kleinman H, Olshan RZ, Ruschin S.
PMID: 9900241
Phys Rev A Gen Phys. 1988 Nov 15;38(10):5206-5216. doi: 10.1103/physreva.38.5206.

No abstract available.

Identification of a Novel Inflamed Tumor Microenvironment Signature as a Predictive Biomarker of Bacillus Calmette-Guérin Immunotherapy in Non-Muscle-Invasive Bladder Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Damrauer JS, Roell KR, Smith MA, Sun X, Kirk EL, Hoadley KA, Benefield HC, Iyer G, Solit DB, Milowsky MI, Kim WY, Nielsen ME, Wobker SE, Dalbagni G, Al-Ahmadie HA, Olshan AF, Bochner BH, Furberg H, Troester MA, Pietzak EJ.
PMID: 34117034
Clin Cancer Res. 2021 Aug 15;27(16):4599-4609. doi: 10.1158/1078-0432.CCR-21-0205. Epub 2021 Jun 11.

PURPOSE: Improved risk stratification and predictive biomarkers of treatment response are needed for non-muscle-invasive bladder cancer (NMIBC). Here we assessed the clinical utility of targeted RNA and DNA molecular profiling in NMIBC.EXPERIMENTAL DESIGN: Gene expression in NMIBC samples was...

TP53 Pathway Function, Estrogen Receptor Status, and Breast Cancer Risk Factors in the Carolina Breast Cancer Study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Hurson AN, Abubakar M, Hamilton AM, Conway K, Hoadley KA, Love MI, Olshan AF, Perou CM, Garcia-Closas M, Troester MA.
PMID: 34737209
Cancer Epidemiol Biomarkers Prev. 2022 Jan;31(1):124-131. doi: 10.1158/1055-9965.EPI-21-0661. Epub 2021 Nov 04.

BACKGROUND: TP53 and estrogen receptor (ER) both play essential roles in breast cancer development and progression, with recent research revealing cross-talk between TP53 and ER signaling pathways. Although many studies have demonstrated heterogeneity of risk factor associations across ER...

Integrating biology and access to care in addressing breast cancer disparities: 25 years' research experience in the Carolina Breast Cancer Study.

Current breast cancer reports

Emerson MA, Reeder-Hayes KE, Tipaldos HJ, Bell ME, Sweeney MR, Carey LA, Earp HS, Olshan AF, Troester MA.
PMID: 33815665
Curr Breast Cancer Rep. 2020 Sep;12(3):149-160. doi: 10.1007/s12609-020-00365-0. Epub 2020 May 14.

PURPOSE OF REVIEW: To review research on breast cancer mortality disparities, emphasizing research conducted in the Carolina Breast Cancer Study, with a focus on challenges and opportunities for integration of tumor biology and access characteristics across the cancer care...

Hepatocyte growth factor pathway expression in breast cancer by race and subtype.

Breast cancer research : BCR

Jones GS, Hoadley KA, Olsson LT, Hamilton AM, Bhattacharya A, Kirk EL, Tipaldos HJ, Fleming JM, Love MI, Nichols HB, Olshan AF, Troester MA.
PMID: 34344422
Breast Cancer Res. 2021 Aug 03;23(1):80. doi: 10.1186/s13058-021-01460-5.

BACKGROUND: African American women have the highest risk of breast cancer mortality compared to other racial groups. Differences in tumor characteristics have been implicated as a possible cause; however, the tumor microenvironment may also contribute to this disparity in...

Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals.

HGG advances

Chen H, Majumdar A, Wang L, Kar S, Brown KM, Feng H, Turman C, Dennis J, Easton D, Michailidou K, Simard J, Bishop T, Cheng IC, Huyghe JR, Schmit SL, O'Mara TA, Spurdle AB, Gharahkhani P, Schumacher J, Jankowski J, Gocke I, Bondy ML, Houlston RS, Jenkins RB, Melin B, Lesseur C, Ness AR, Diergaarde B, Olshan AF, Amos CI, Christiani DC, Landi MT, McKay JD, Brossard M, Iles MM, Law MH, MacGregor S, Beesley J, Jones MR, Tyrer J, Winham SJ, Klein AP, Petersen G, Li D, Wolpin BM, Eeles RA, Haiman CA, Kote-Jarai Z, Schumacher FR, Brennan P, Chanock SJ, Gaborieau V, Purdue MP, Pharoah P, Hung RJ, Amundadottir LT, Kraft P, Pasaniuc B, Lindström S.
PMID: 34355204
HGG Adv. 2021 Jul 08;2(3). doi: 10.1016/j.xhgg.2021.100041. Epub 2021 Jun 12.

Genome-wide association studies (GWASs) have identified thousands of cancer risk loci revealing many risk regions shared across multiple cancers. Characterizing the cross-cancer shared genetic basis can increase our understanding of global mechanisms of cancer development. In this study, we...

Showing 1 to 12 of 115 entries