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Osteoporosis in men: findings from the Osteoporotic Fractures in Men Study (MrOS).

Therapeutic advances in musculoskeletal disease

Cawthon PM, Shahnazari M, Orwoll ES, Lane NE.
PMID: 26834847
Ther Adv Musculoskelet Dis. 2016 Feb;8(1):15-27. doi: 10.1177/1759720X15621227.

The lifespan of men is increasing and this is associated with an increased prevalence of osteoporosis in men. Osteoporosis increases the risk of bone fracture. Fractures are associated with increased disability and mortality, and public health problems. We review...

Osteoporosis in men.

Journal of musculoskeletal & neuronal interactions

Orwoll ES.
PMID: 15758437
J Musculoskelet Neuronal Interact. 2002 Mar;2(3):219.

No abstract available.

Clinical experience with intravenous zoledronic acid in the treatment of male osteoporosis: evidence and opinions.

Therapeutic advances in musculoskeletal disease

Ruza I, Mirfakhraee S, Orwoll E, Gruntmanis U.
PMID: 23904863
Ther Adv Musculoskelet Dis. 2013 Aug;5(4):182-98. doi: 10.1177/1759720X13485829.

Osteoporosis frequently remains underrecognized and undertreated in men. Most osteoporosis-related fractures could be prevented if men at risk would be diagnosed, treated, and remained compliant with therapy. Bisphosphonates, the mainstay of osteoporosis treatment, are potent antiresorptive agents that inhibit...

Hip load capacity cut-points for Astronaut Skeletal Health NASA Finite Element Strength Task Group Recommendations.

NPJ microgravity

Michalski AS, Amin S, Cheung AM, Cody DD, Keyak JH, Lang TF, Nicolella DP, Orwoll ES, Boyd SK, Sibonga JD.
PMID: 30886891
NPJ Microgravity. 2019 Mar 14;5:6. doi: 10.1038/s41526-019-0066-3. eCollection 2019.

Concerns raised at a 2010 Bone Summit held for National Aeronautics and Space Administration Johnson Space Center led experts in finite element (FE) modeling for hip fracture prediction to propose including hip load capacity in the standards for astronaut...

Comparing identified and statistically significant lipids and polar metabolites in 15-year old serum and dried blood spot samples for longitudinal studies.

Rapid communications in mass spectrometry : RCM

Kyle JE, Casey CP, Stratton KG, Zink EM, Kim YM, Zheng X, Monroe ME, Weitz KK, Bloodsworth KJ, Orton DJ, Ibrahim YM, Moore RJ, Lee CG, Pedersen C, Orwoll E, Smith RD, Burnum-Johnson KE, Baker ES.
PMID: 27958645
Rapid Commun Mass Spectrom. 2017 Mar 15;31(5):447-456. doi: 10.1002/rcm.7808.

RATIONALE: The use of dried blood spots (DBS) has many advantages over traditional plasma and serum samples such as the smaller blood volume required, storage at room temperature, and ability to sample in remote locations. However, understanding the robustness...

Genetic Burden Contributing to Extremely Low or High Bone Mineral Density in a Senior Male Population From the Osteoporotic Fractures in Men Study (MrOS).

JBMR plus

Chen S, Jain M, Jhangiani S, Akdemir ZC, Campeau PM, Klein RF, Nielson C, Dai H, Muzny DM, Boerwinkle E, Gibbs RA, Orwoll ES, Lupski JR, Posey JE, Lee B.
PMID: 32161841
JBMR Plus. 2020 Jan 22;4(3):e10335. doi: 10.1002/jbm4.10335. eCollection 2020 Mar.

Worldwide, one in five men aged over 50 years will experience osteoporosis or a clinical bone fracture, with a greater fracture-related mortality rate than women. However, the genetic etiology of osteoporosis in men is still poorly understood. We aimed...

Muscle Strength and Physical Performance Improve Fracture Risk Prediction Beyond Garvan and FRAX: The Osteoporotic Fractures in Men (MrOS) Study.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Alajlouni D, Tran T, Bliuc D, Blank RD, Cawthon PM, Orwoll ES, Center JR.
PMID: 34842309
J Bone Miner Res. 2021 Nov 29; doi: 10.1002/jbmr.4483. Epub 2021 Nov 29.

Muscle strength and physical performance are associated with fracture risk in men. However, it is not known whether these measurements enhance fracture prediction beyond Garvan and FRAX tools. A total of 5665 community-dwelling men, aged ≥65 years, from the...

Endogenous Testosterone Levels and the Risk of Incident Cardiovascular Events in Elderly Men: The MrOS Prospective Study.

Journal of the Endocrine Society

Collet TH, Ewing SK, Ensrud KE, Laughlin GA, Hoffman AR, Varosy PD, Stefanick ML, Stone KL, Orwoll E, Bauer DC.
PMID: 32337470
J Endocr Soc. 2020 Mar 24;4(5):bvaa038. doi: 10.1210/jendso/bvaa038. eCollection 2020 May 01.

CONTEXT: Observational studies show discordant links between endogenous testosterone levels and cardiovascular diseases (CVD).OBJECTIVE: We assessed whether sex hormones and sex hormone-binding globulin (SHBG) are associated with CVD in community-dwelling elderly men.DESIGN SETTING AND PARTICIPANTS: Prospective study of incident...

Corrigendum to: CT Muscle Density, D3Cr Muscle Mass, and Body Fat Associations With Physical Performance, Mobility Outcomes, and Mortality Risk in Older Men.

The journals of gerontology. Series A, Biological sciences and medical sciences

Orwoll ES, Blackwell T, Cummings SR, Cauley JA, Lane NE, Hoffman AR, Burghardt AJ, Evans WJ, Cawthon PM.
PMID: 34940807
J Gerontol A Biol Sci Med Sci. 2021 Dec 23; doi: 10.1093/gerona/glab364. Epub 2021 Dec 23.

No abstract available.

A qualitative study of provider burnout: do medical scribes hinder or help?.

JAMIA open

Corby S, Ash JS, Mohan V, Becton J, Solberg N, Bergstrom R, Orwoll B, Hoekstra C, Gold JA.
PMID: 34396055
JAMIA Open. 2021 Aug 12;4(3):ooab047. doi: 10.1093/jamiaopen/ooab047. eCollection 2021 Jul.

OBJECTIVE: Provider burnout is a crisis in healthcare and leads to medical errors, a decrease in patient satisfaction, and provider turnover. Many feel that the increased use of electronic health records contributes to the rate of burnout. To avoid...

Successful collection of stool samples for microbiome analyses from a large community-based population of elderly men.

Contemporary clinical trials communications

Abrahamson M, Hooker E, Ajami NJ, Petrosino JF, Orwoll ES.
PMID: 29250605
Contemp Clin Trials Commun. 2017 Sep;7:158-162. doi: 10.1016/j.conctc.2017.07.002. Epub 2017 Jul 06.

The relationship of the gastrointestinal microbiome to health and disease is of major research interest, including the effects of the gut microbiota on age related conditions. Here we report on the outcome of a project to collect stool samples...

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Nature communications

Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker SCJ, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stančáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP.
PMID: 29116125
Nat Commun. 2017 Nov 07;8(1):1414. doi: 10.1038/s41467-017-01008-2.

A correction to this article has been published and is linked from the HTML version of this article.

Showing 1 to 12 of 37 entries