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Showing 1 to 12 of 19 entries
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Review of Laboratory Tests used in Monitoring Hepatitis B Response to Pegylated Interferon and Nucleos(t)ide Analog Therapy.

Current treatment options in infectious diseases

Osiowy C, Coffin C, Andonov A.
PMID: 27547127
Curr Treat Options Infect Dis. 2016;8:177-193. doi: 10.1007/s40506-016-0080-x. Epub 2016 Jul 02.

There are only two currently approved classes of hepatitis B virus (HBV) antiviral agents, pegylated interferon (Peg-IFN), and nucleos(t)ide analogs (NAs) for chronic HBV infection. Although Peg-IFN is used for a finite 48-week duration and offers a greater chance...

Correction: Hepatitis B Virus (HBV) Variants in Untreated and Tenofovir Treated Chronic Hepatitis B (CHB) Patients During Pregnancy and Post-Partum Follow-up.

PloS one

Virine B, Osiowy C, Gao S, Wang T, Castillo E, Martin SR, Lee SS, Simmonds K, van Marle G, Coffin CS.
PMID: 26690969
PLoS One. 2015 Dec 21;10(12):e0145898. doi: 10.1371/journal.pone.0145898. eCollection 2015.

No abstract available.

Novel Biomarkers of Hepatitis B Virus and Their Use in Chronic Hepatitis B Patient Management.

Viruses

Vachon A, Osiowy C.
PMID: 34064049
Viruses. 2021 May 21;13(6). doi: 10.3390/v13060951.

Even though an approved vaccine for hepatitis B virus (HBV) is available and widely used, over 257 million individuals worldwide are living with chronic hepatitis B (CHB) who require monitoring of treatment response, viral activity, and disease progression to...

Novel Biomarkers of Hepatitis B Virus and Their Use in Chronic Hepatitis B Patient Management.

Viruses

Vachon A, Osiowy C.
PMID: 34064049
Viruses. 2021 May 21;13(6). doi: 10.3390/v13060951.

Even though an approved vaccine for hepatitis B virus (HBV) is available and widely used, over 257 million individuals worldwide are living with chronic hepatitis B (CHB) who require monitoring of treatment response, viral activity, and disease progression to...

Dried blood spot specimens for SARS-CoV-2 antibody testing: A multi-site, multi-assay comparison.

PloS one

Cholette F, Mesa C, Harris A, Ellis H, Cachero K, Lacap P, Galipeau Y, Langlois MA, Gingras AC, Yansouni CP, Papenburg J, Cheng MP, Chakraborty P, Stein DR, Van Caeseele P, Bartlett S, Krajden M, Goldfarb D, McGeer A, Osiowy C, Hankins C, Mazer B, Drebot M, Kim J.
PMID: 34874948
PLoS One. 2021 Dec 07;16(12):e0261003. doi: 10.1371/journal.pone.0261003. eCollection 2021.

The true severity of infection due to COVID-19 is under-represented because it is based on only those who are tested. Although nucleic acid amplifications tests (NAAT) are the gold standard for COVID-19 diagnostic testing, serological assays provide better population-level...

Public health response to a large-scale endoscopy infection control lapse in a nonhospital clinic.

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

Willmore J, Ellis E, Etches V, Labrecque L, Osiowy C, Andonov A, McDermaid C, Majury A, Achonu C, Maher M, MacLean B, Levy I.
PMID: 26015789
Can J Infect Dis Med Microbiol. 2015 Mar-Apr;26(2):77-84. doi: 10.1155/2015/160536.

OBJECTIVE: To determine whether transmission of blood-borne pathogens (BBPs) (hepatitis B virus [HBV], hepatitis C virus [HCV] and HIV) occurred as a result of endoscopy reprocessing failures identified during an inspection of a nonhospital endoscopy clinic in 2011.METHODS: The...

Editorial: Origin and Evolution of Hepatitis Viruses.

Frontiers in microbiology

Osiowy C, Yuen L.
PMID: 34512616
Front Microbiol. 2021 Aug 25;12:740255. doi: 10.3389/fmicb.2021.740255. eCollection 2021.

No abstract available.

Social Capital and Autism in Young Adulthood: Applying Social Network Methods to Measure the Social Capital of Autistic Young Adults.

Autism in adulthood : challenges and management

McGhee Hassrick E, Sosnowy C, Graham Holmes L, Walton J, Shattuck PT.
PMID: 32954220
Autism Adulthood. 2020 Sep 01;2(3):243-254. doi: 10.1089/aut.2019.0058. Epub 2020 Sep 03.

Social isolation is a core challenge associated with autism. Interpersonal relationships and the resources and support embedded in the social networks of autistic young adults could impact key adult outcomes, including quality of life, mental health, employment, and independence....

Analysis of Hepatitis B Virus Genotype D in Greenland Suggests the Presence of a Novel Quasi-Subgenotype.

Frontiers in microbiology

de Bernardi Schneider A, Osiowy C, Hostager R, Krarup H, Børresen M, Tanaka Y, Morriseau T, Wertheim JO.
PMID: 33519744
Front Microbiol. 2021 Jan 15;11:602296. doi: 10.3389/fmicb.2020.602296. eCollection 2020.

A disproportionate number of Greenland's Inuit population are chronically infected with Hepatitis B virus (HBV; 5-10%). HBV genotypes B and D are most prevalent in the circumpolar Arctic. Here, we report 39 novel HBV/D sequences from individuals residing in...

Tracing hepatitis B virus (HBV) genotype B5 (formerly B6) evolutionary history in the circumpolar Arctic through phylogeographic modelling.

PeerJ

Bouckaert R, Simons BC, Krarup H, Friesen TM, Osiowy C.
PMID: 28875087
PeerJ. 2017 Aug 31;5:e3757. doi: 10.7717/peerj.3757. eCollection 2017.

BACKGROUND: Indigenous populations of the circumpolar Arctic are considered to be endemically infected (>2% prevalence) with hepatitis B virus (HBV), with subgenotype B5 (formerly B6) unique to these populations. The distinctive properties of HBV/B5, including high nucleotide diversity yet...

Hepatitis B Virus Infection of Normal Hepatic Stem/Progenitor Cells.

Journal of clinical and experimental hepatology

Bautista WW, Osiowy C, Klein J, Minuk GY.
PMID: 30765937
J Clin Exp Hepatol. 2019 Jan-Feb;9(1):34-42. doi: 10.1016/j.jceh.2018.02.002. Epub 2018 Feb 16.

BACKGROUND/AIMS: Whether the hepatitis B virus (HBV) infects normal hepatic stem/progenitor cells (NSCs) and if so, whether such infections play a role in the pathogenesis of HBV-induced chronic liver disease (CLD) and/or hepatocellular carcinoma (HCC) remains to be determined....

Effect of Processing on Postprandial Glycemic Response and Consumer Acceptability of Lentil-Containing Food Items.

Foods (Basel, Switzerland)

Ramdath DD, Wolever TMS, Siow YC, Ryland D, Hawke A, Taylor C, Zahradka P, Aliani M.
PMID: 29751679
Foods. 2018 May 11;7(5). doi: 10.3390/foods7050076.

The consumption of pulses is associated with many health benefits. This study assessed post-prandial blood glucose response (PPBG) and the acceptability of food items containing green lentils. In human trials we: (i) defined processing methods (boiling, pureeing, freezing, roasting,...

Showing 1 to 12 of 19 entries