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Showing 1 to 12 of 37 entries
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Patients with high serum substance P levels previously to liver transplantation for hepatocellular carcinoma have higher risk of one-year liver transplantation mortality.

Oncotarget

Lorente L, Rodriguez ST, Sanz P, Pérez-Cejas A, Padilla J, Díaz D, González A, Martín MM, Jiménez A, Cerro P, Barrera MA.
PMID: 29765559
Oncotarget. 2018 Apr 20;9(30):21552-21559. doi: 10.18632/oncotarget.25097. eCollection 2018 Apr 20.

PURPOSE: Substance P is a tachykinins family member with inflammatory effects. Higher circulating levels of substance P have been found in patients with liver diseases and in patients with higher severity of liver diseases. The objective of this study...

Colonization Resistance of the Gut Microbiota against Clostridium difficile.

Antibiotics (Basel, Switzerland)

Pérez-Cobas AE, Moya A, Gosalbes MJ, Latorre A.
PMID: 27025628
Antibiotics (Basel). 2015 Aug 07;4(3):337-57. doi: 10.3390/antibiotics4030337.

Antibiotics strongly disrupt the human gut microbiota, which in consequence loses its colonization resistance capacity, allowing infection by opportunistic pathogens such as Clostridium difficile. This bacterium is the main cause of antibiotic-associated diarrhea and a current problem in developed...

Association between serum concentrations of anti-apoptotic B-cell lymphoma-2 protein and traumatic brain injury mortality.

Expert review of molecular diagnostics

Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Ferrer-Moure C, Jiménez A.
PMID: 34878357
Expert Rev Mol Diagn. 2021 Dec 08; doi: 10.1080/14737159.2022.2016394. Epub 2021 Dec 08.

BACKGROUND: There are scarce and contradictory data exist about B-cell lymphoma 2 (Bcl2), one of Bcl2 family of anti-apoptotic proteins, in traumatic brain injury (TBI) patients. Thus, the objective of this study was to analyze whether blood concentrations of...

Association of serum soluble Fas concentrations and mortality of septic patients.

Enfermedades infecciosas y microbiologia clinica (English ed.)

Lorente L, Martín MM, Ortiz-López R, González-Rivero AF, Pérez-Cejas A, Pastor E, Domínguez-Curell C, Raja L, Lorenzo L, Jiménez A.
PMID: 32972791
Enferm Infecc Microbiol Clin (Engl Ed). 2020 Sep 21; doi: 10.1016/j.eimc.2020.08.003. Epub 2020 Sep 21.

INTRODUCTION: Scarce data on Fas, one of the main receptors that activates the apoptosis extrinsic pathway, in septic patients exists. Higher blood soluble Fas (sFas) concentrations in non-survivor septic patients compared with survivors have been found in small studies;...

Mortality prediction of patients with spontaneous intracerebral hemorrhage by serum soluble Fas ligand concentrations.

Expert review of molecular diagnostics

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Cabrera J, Uribe L, Ferrer-Moure C, Jiménez A.
PMID: 34894981
Expert Rev Mol Diagn. 2021 Dec 22;1-6. doi: 10.1080/14737159.2022.2017775. Epub 2021 Dec 22.

BACKGROUND: A study of patients with spontaneous intracerebral hemorrhage (SIH) found a higher content of Fas ligand in the perihematomic brain area compared to healthy brain areas. The objective of this study was to analyze whether blood soluble Fas...

Low blood caspase-8 levels in survivor patients of traumatic brain injury.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

Lorente L, Martín MM, Pérez-Cejas A, González-Rivero AF, Ramos-Gómez L, Solé-Violán J, Cáceres JJ, Ferrer-Moure C, Jiménez A.
PMID: 33759054
Neurol Sci. 2021 Dec;42(12):5065-5070. doi: 10.1007/s10072-021-05205-2. Epub 2021 Mar 23.

OBJECTIVE: High concentrations of caspase-8 (main initiator caspase of the extrinsic pathway of apoptosis) have been found in brain tissue of patients with traumatic brain injury (TBI) and in the blood of patients with different diseases. However, blood caspase-8...

Association between total antioxidant capacity and mortality in ischemic stroke patients.

Annals of intensive care

Lorente L, Martín MM, Pérez-Cejas A, Abreu-González P, Ramos L, Argueso M, Cáceres JJ, Solé-Violán J, Jiménez A.
PMID: 27107565
Ann Intensive Care. 2016 Dec;6(1):39. doi: 10.1186/s13613-016-0143-7. Epub 2016 Apr 23.

OBJECTIVE: Data on circulating total antioxidant capacity (TAC) levels in ischemic stroke patients compared with healthy controls are limited and provided conflicting findings. There are not data about the association between circulating TAC levels, peroxidation state and outcome in...

Nanoscale investigation of AlGaN/GaN-on-Si high electron mobility transistors.

Nanotechnology

Fontserè A, Pérez-Tomás A, Placidi M, Llobet J, Baron N, Chenot S, Cordier Y, Moreno JC, Jennings MR, Gammon PM, Fisher CA, Iglesias V, Porti M, Bayerl A, Lanza M, Nafría M.
PMID: 22971927
Nanotechnology. 2012 Oct 05;23(39):395204. doi: 10.1088/0957-4484/23/39/395204. Epub 2012 Sep 12.

AlGaN/GaN HEMTs are devices which are strongly influenced by surface properties such as donor states, roughness or any kind of inhomogeneity. The electron gas is only a few nanometers away from the surface and the transistor forward and reverse...

Above-Bandgap Photovoltages in Antiferroelectrics.

Advanced materials (Deerfield Beach, Fla.)

Pérez-Tomás A, Lira-Cantú M, Catalan G.
PMID: 27629252
Adv Mater. 2016 Nov;28(43):9644-9647. doi: 10.1002/adma.201603176. Epub 2016 Sep 15.

The first antiferroelectric solar cell is presented. This study shows that antiferroelectric thin-film photovoltaic current can be switched on when biased into the polar phase to generate abovebandgap photovoltages in excess of 100 V and photovoltaic fields of several...

Unraveling Assemblage, Functions and Stability of the Gut Microbiota of .

Frontiers in microbiology

Domínguez-Santos R, Pérez-Cobas AE, Artacho A, Castro JA, Talón I, Moya A, García-Ferris C, Latorre A.
PMID: 32269557
Front Microbiol. 2020 Mar 25;11:487. doi: 10.3389/fmicb.2020.00487. eCollection 2020.

Symbiosis between prokaryotes and eukaryotes is a widespread phenomenon that has contributed to the evolution of eukaryotes. In cockroaches, two types of symbionts coexist: an endosymbiont in the fat body (

DNA and RNA oxidative damage are associated to mortality in patients with cerebral infarction.

Medicina intensiva

Lorente L, Martín MM, González-Rivero AF, Pérez-Cejas A, Abreu-González P, Ramos L, Argueso M, Cáceres JJ, Solé-Violán J, Alvarez-Castillo A, Jiménez A, García-Marín V.
PMID: 31492477
Med Intensiva (Engl Ed). 2021 Jan-Feb;45(1):35-41. doi: 10.1016/j.medin.2019.07.008. Epub 2019 Sep 03.

OBJECTIVE: Secondary injury due to oxidation may occur during ischemic stroke, possibly leading to oxidative damage to deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Higher blood concentrations of 8-hydroxy-2'-deoxyguanosine (8-OHdG) (through the oxidation of guanosine from DNA) have been...

Structural and functional changes in the gut microbiota associated to Clostridium difficile infection.

Frontiers in microbiology

Pérez-Cobas AE, Artacho A, Ott SJ, Moya A, Gosalbes MJ, Latorre A.
PMID: 25309515
Front Microbiol. 2014 Jul 04;5:335. doi: 10.3389/fmicb.2014.00335. eCollection 2014.

Antibiotic therapy is a causative agent of severe disturbances in microbial communities. In healthy individuals, the gut microbiota prevents infection by harmful microorganisms through direct inhibition (releasing antimicrobial compounds), competition, or stimulation of the host's immune defenses. However, widespread...

Showing 1 to 12 of 37 entries