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Showing 1 to 12 of 123 entries
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Target Identification of .

Frontiers in pharmacology

Mugumbate G, Mendes V, Blaszczyk M, Sabbah M, Papadatos G, Lelievre J, Ballell L, Barros D, Abell C, Blundell TL, Overington JP.
PMID: 29018348
Front Pharmacol. 2017 Sep 26;8:681. doi: 10.3389/fphar.2017.00681. eCollection 2017.

Mycobacterium phenotypic hits are a good reservoir for new chemotypes for the treatment of tuberculosis. However, the absence of defined molecular targets and modes of action could lead to failure in drug development. Therefore, a combination of ligand-based and...

Unexpected combination of acute croup and myocarditis: case report.

BMC clinical pathology

Briassoulis G, Tsorva A, Agapitos E, Papadatos J.
PMID: 15941482
BMC Clin Pathol. 2005 Jun 07;5:5. doi: 10.1186/1472-6890-5-5.

BACKGROUND: Lower vaccination coverage among foreign-born children is of concern because they live in households and communities characterized by more intense exposure to infectious diseases. Because of their higher prevalence rates, there is an increasing occurrence of infectious diseases...

Diagnosis and management of hepatocellular carcinoma: results of a consensus meeting of The Ottawa Hospital Cancer Centre.

Current oncology (Toronto, Ont.)

Asmis T, Balaa F, Scully L, Papadatos D, Marginean C, Fasih N, Shaw-Stiffel T, Goel R.
PMID: 20404972
Curr Oncol. 2010 Apr;17(2):6-12. doi: 10.3747/co.v17i2.555.

Hepatocellular carcinoma (HCC) is an uncommon tumour, but its incidence is increasing in Canada and elsewhere. Currently, there are no Canadian recommendations for diagnosis and treatment of hcc, and possible options may have regional limitations. A consensus symposium was...

Draft Genome Sequence of the Gammaproteobacterial Strain MOLA455, a Representative of a Ubiquitous Proteorhodopsin-Producing Group in the Ocean.

Genome announcements

Courties A, Riedel T, Jarek M, Papadatou M, Intertaglia L, Lebaron P, Suzuki MT.
PMID: 24482511
Genome Announc. 2014 Jan 30;2(1). doi: 10.1128/genomeA.01203-13.

Strain MOLA455 is a marine gammaproteobacterium isolated from the bay of Banyuls-sur-Mer, France. Here, we present its genome sequence and annotation. Genome analysis revealed the presence of genes associated with a possibly photoheterotrophic lifestyle that uses a proteorhodopsin protein.

UniChem: extension of InChI-based compound mapping to salt, connectivity and stereochemistry layers.

Journal of cheminformatics

Chambers J, Davies M, Gaulton A, Papadatos G, Hersey A, Overington JP.
PMID: 25221628
J Cheminform. 2014 Sep 04;6(1):43. doi: 10.1186/s13321-014-0043-5. eCollection 2014 Dec.

UniChem is a low-maintenance, fast and freely available compound identifier mapping service, recently made available on the Internet. Until now, the criterion of molecular equivalence within UniChem has been on the basis of complete identity between Standard InChIs. However,...

Primary biliary cirrhosis in HBV and HCV patients: Clinical characteristics and outcome.

World journal of hepatology

Rigopoulou EI, Zachou K, Gatselis NK, Papadamou G, Koukoulis GK, Dalekos GN.
PMID: 24179617
World J Hepatol. 2013 Oct 27;5(10):577-83. doi: 10.4254/wjh.v5.i10.577.

AIM: To present the characteristics, management and outcome of patients with hepatitis B virus (HBV) or hepatitis C virus (HCV) infections concurrent with primary biliary cirrhosis (PBC).METHODS: Since January 2001 to September 2009, we retrospectively evaluated the medical records...

Prolonged Detection of Japanese Encephalitis Virus in Urine and Whole Blood in a Returned Short-term Traveler.

Open forum infectious diseases

Huang GKL, Tio SY, Caly L, Nicholson S, Thevarajan I, Papadakis G, Catton M, Tong SYC, Druce J.
PMID: 29226169
Open Forum Infect Dis. 2017 Sep 27;4(4):ofx203. doi: 10.1093/ofid/ofx203. eCollection 2017.

We describe a fatal case of Japanese encephalitis virus infection following short-term travel to Thailand. Viral RNA was detected in urine and whole blood out to 26 and 28 days, respectively, after the onset of symptoms. Live virus was...

Pneumococcal Vaccines: Challenges and Prospects.

Vaccines

Licciardi P, Papadatou I.
PMID: 30818791
Vaccines (Basel). 2019 Feb 27;7(1). doi: 10.3390/vaccines7010025.

Infections with the bacterium

Validation of a spectral light scattering method to differentiate large from small particles in intraocular lenses.

Biomedical optics express

Łabuz G, Papadatou E, Vargas-Martín F, López-Gil N, Reus NJ, van den Berg TJTP.
PMID: 28663871
Biomed Opt Express. 2017 Feb 27;8(3):1889-1894. doi: 10.1364/BOE.8.001889. eCollection 2017 Mar 01.

A psychophysical approach has been designed to measure straylight from intraocular lenses (IOLs)

Pedicle distraction increases intervertebral and spinal canal area in a cadaver and bone model.

SICOT-J

Hughes M, Papadakos N, Bishop T, Bernard J.
PMID: 29727270
SICOT J. 2018;4:15. doi: 10.1051/sicotj/2018009. Epub 2018 May 04.

INTRODUCTION: Lumbar spinal stenosis is degenerative narrowing of the spinal canal and/or intervertebral foramen causing compression of the spinal cord and nerve roots. Traditional decompression techniques can often cause significant trauma and vertebral instability. This paper evaluates a method...

High-grade blunt traumatic rupture of kidney transplant: is conservative management an option?.

Annals of the Royal College of Surgeons of England

Papadakis G, Dost S, Kunduzi B, Olsburgh J, Brown C, Mamode N, Karydis N.
PMID: 34825827
Ann R Coll Surg Engl. 2021 Nov 26; doi: 10.1308/rcsann.2021.0167. Epub 2021 Nov 26.

Road traffic accidents are the most common cause of blunt native kidney injuries. Transplanted kidneys are more exposed to such injuries due to the common positioning in the iliac fossa compared with the relatively protected position of the native...

Pneumococcal Immunization Strategies for High-Risk Pediatric Populations Worldwide: One Size Does Not Fit All.

Vaccines

Lagousi T, Papadatou I, Strempas P, Chatzikalil E, Spoulou V.
PMID: 34960136
Vaccines (Basel). 2021 Nov 24;9(12). doi: 10.3390/vaccines9121390.

Despite the significant reduction in pneumococcal disease due to pneumococcal vaccines, protection of vulnerable high-risk individuals, especially pediatric populations, remains a great challenge. In an effort to maximize the protection of high-risk children against pneumococcal disease, a combined schedule...

Showing 1 to 12 of 123 entries