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Targeting metabolism to regulate immune responses in autoimmunity and cancer

interventions

Patel CH.
GSID: WSL070LNqeYJ
CH Patel, RD Leone, MR Horton… - Nature Reviews Drug …, 2019 - nature.com

Metabolic programming is emerging as a critical mechanism to alter immune cell activation, differentiation and function. Targeting metabolism does not completely suppress or activate …

Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study.

Neurology. Genetics

Traylor M, Rutten-Jacobs L, Curtis C, Patel H, Breen G, Newhouse S, Lewis CM, Markus HS.
PMID: 28349126
Neurol Genet. 2017 Mar 15;3(2):e142. doi: 10.1212/NXG.0000000000000142. eCollection 2017 Apr.

OBJECTIVE: Despite epidemiologic data showing an increased stroke incidence in African ancestry populations, genetic studies in this group have so far been limited, and there has been little characterization of the genetic contribution to stroke liability in this population,...

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Traylor M, Rutten-Jacobs L, Curtis C, et al. Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study. Neurol Genet. 2017;3(2):e142doi: 10.1212/NXG.0000000000000142.
Traylor, M., Rutten-Jacobs, L., Curtis, C., Patel, H., Breen, G., Newhouse, S., Lewis, C. M., & Markus, H. S. (2017). Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study. Neurology. Genetics, 3(2), e142. https://doi.org/10.1212/NXG.0000000000000142
Traylor, Matthew, et al. "Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study." Neurology. Genetics vol. 3,2 (2017): e142. doi: https://doi.org/10.1212/NXG.0000000000000142
Traylor M, Rutten-Jacobs L, Curtis C, Patel H, Breen G, Newhouse S, Lewis CM, Markus HS. Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study. Neurol Genet. 2017 Mar 15;3(2):e142. doi: 10.1212/NXG.0000000000000142. eCollection 2017 Apr. PMID: 28349126; PMCID: PMC5354108.
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Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites.

Case reports in gastroenterology

Abdulsamad M, Abbas N, Patel H, Balar B, Khaja M.
PMID: 28512393
Case Rep Gastroenterol. 2017 Apr 10;11(1):201-206. doi: 10.1159/000468516. eCollection 2017.

Multiple myeloma (MM) is a neoplastic proliferation of plasma cells with overproduction of monoclonal immunoglobulins and infiltration into the bone and other organs. Ascites can develop in patients with lymphoproliferative and solid malignancies involving the peritoneum. However, ascites is...

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Abdulsamad M, Abbas N, Patel H, et al. Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites. Case Rep Gastroenterol. 2017;11(1):201-206doi: 10.1159/000468516.
Abdulsamad, M., Abbas, N., Patel, H., Balar, B., & Khaja, M. (2017). Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites. Case reports in gastroenterology, 11(1), 201-206. https://doi.org/10.1159/000468516
Abdulsamad, Molham, et al. "Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites." Case reports in gastroenterology vol. 11,1 (2017): 201-206. doi: https://doi.org/10.1159/000468516
Abdulsamad M, Abbas N, Patel H, Balar B, Khaja M. Immunoglobulin A Lambda Multiple Myeloma in a Patient with HIV: An Unusual Cause of Massive Ascites. Case Rep Gastroenterol. 2017 Apr 10;11(1):201-206. doi: 10.1159/000468516. eCollection 2017. PMID: 28512393; PMCID: PMC5422736.
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Comparative Evaluation of Efficacy of Physics Forceps versus Conventional Forceps in Orthodontic Extractions: A Prospective Randomized Split Mouth Study.

Journal of clinical and diagnostic research : JCDR

Patel HS, Managutti AM, Menat S, Agarwal A, Shah D, Patel J.
PMID: 27630951
J Clin Diagn Res. 2016 Jul;10(7):ZC41-5. doi: 10.7860/JCDR/2016/17724.8160. Epub 2016 Jul 01.

INTRODUCTION: Tooth extraction is one of the most commonly performed procedures in dentistry. It is usually a traumatic procedure often resulting in immediate destruction and loss of alveolar bone and surrounding soft tissues. Various instruments have been described to...

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Patel HS, Managutti AM, Menat S, et al. Comparative Evaluation of Efficacy of Physics Forceps versus Conventional Forceps in Orthodontic Extractions: A Prospective Randomized Split Mouth Study. J Clin Diagn Res. 2016;10(7):ZC41-5doi: 10.7860/JCDR/2016/17724.8160.
Patel, H. S., Managutti, A. M., Menat, S., Agarwal, A., Shah, D., & Patel, J. (2016). Comparative Evaluation of Efficacy of Physics Forceps versus Conventional Forceps in Orthodontic Extractions: A Prospective Randomized Split Mouth Study. Journal of clinical and diagnostic research : JCDR, 10(7), ZC41-5. https://doi.org/10.7860/JCDR/2016/17724.8160
Patel, Harsh S, et al. "Comparative Evaluation of Efficacy of Physics Forceps versus Conventional Forceps in Orthodontic Extractions: A Prospective Randomized Split Mouth Study." Journal of clinical and diagnostic research : JCDR vol. 10,7 (2016): ZC41-5. doi: https://doi.org/10.7860/JCDR/2016/17724.8160
Patel HS, Managutti AM, Menat S, Agarwal A, Shah D, Patel J. Comparative Evaluation of Efficacy of Physics Forceps versus Conventional Forceps in Orthodontic Extractions: A Prospective Randomized Split Mouth Study. J Clin Diagn Res. 2016 Jul;10(7):ZC41-5. doi: 10.7860/JCDR/2016/17724.8160. Epub 2016 Jul 01. PMID: 27630951; PMCID: PMC5020268.
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Significance of Interleukin-6 in Papillary Thyroid Carcinoma.

Journal of thyroid research

Kobawala TP, Trivedi TI, Gajjar KK, Patel DH, Patel GH, Ghosh NR.
PMID: 27034885
J Thyroid Res. 2016;2016:6178921. doi: 10.1155/2016/6178921. Epub 2016 Mar 13.

This study sought to reveal the significance of IL-6 in papillary thyroid carcinoma by determining its circulating levels, tumoral protein, and mRNA expressions. As compared to the healthy individuals, serum IL-6 was significantly higher in patients with benign thyroid...

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Kobawala TP, Trivedi TI, Gajjar KK, et al. Significance of Interleukin-6 in Papillary Thyroid Carcinoma. J Thyroid Res. 2016;2016:6178921doi: 10.1155/2016/6178921.
Kobawala, T. P., Trivedi, T. I., Gajjar, K. K., Patel, D. H., Patel, G. H., & Ghosh, N. R. (2016). Significance of Interleukin-6 in Papillary Thyroid Carcinoma. Journal of thyroid research, 20166178921. https://doi.org/10.1155/2016/6178921
Kobawala, Toral P, et al. "Significance of Interleukin-6 in Papillary Thyroid Carcinoma." Journal of thyroid research vol. 2016 (2016): 6178921. doi: https://doi.org/10.1155/2016/6178921
Kobawala TP, Trivedi TI, Gajjar KK, Patel DH, Patel GH, Ghosh NR. Significance of Interleukin-6 in Papillary Thyroid Carcinoma. J Thyroid Res. 2016;2016:6178921. doi: 10.1155/2016/6178921. Epub 2016 Mar 13. PMID: 27034885; PMCID: PMC4808558.
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Corrigendum: Lanosterol reverses protein aggregation in cataracts.

Nature

Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Perry JJ, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K.
PMID: 26308894
Nature. 2015 Oct 22;526(7574):595. doi: 10.1038/nature15253. Epub 2015 Aug 26.

No abstract available.

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Zhao L, Chen XJ, Zhu J, et al. Corrigendum: Lanosterol reverses protein aggregation in cataracts. Nature. 2015;526(7574):595doi: 10.1038/nature15253.
Zhao, L., Chen, X. J., Zhu, J., Xi, Y. B., Yang, X., Hu, L. D., Ouyang, H., Patel, S. H., Jin, X., Lin, D., Wu, F., Flagg, K., Cai, H., Li, G., Cao, G., Lin, Y., Chen, D., Wen, C., Chung, C., Wang, Y., Qiu, A., Yeh, E., Wang, W., Hu, X., Grob, S., Abagyan, R., Su, Z., Tjondro, H. C., Zhao, X. J., Luo, H., Hou, R., Perry, J. J., Gao, W., Kozak, I., Granet, D., Li, Y., Sun, X., Wang, J., Zhang, L., Liu, Y., Yan, Y. B., & Zhang, K. (2015). Corrigendum: Lanosterol reverses protein aggregation in cataracts. Nature, 526(7574), 595. https://doi.org/10.1038/nature15253
Zhao, Ling, et al. "Corrigendum: Lanosterol reverses protein aggregation in cataracts." Nature vol. 526,7574 (2015): 595. doi: https://doi.org/10.1038/nature15253
Zhao L, Chen XJ, Zhu J, Xi YB, Yang X, Hu LD, Ouyang H, Patel SH, Jin X, Lin D, Wu F, Flagg K, Cai H, Li G, Cao G, Lin Y, Chen D, Wen C, Chung C, Wang Y, Qiu A, Yeh E, Wang W, Hu X, Grob S, Abagyan R, Su Z, Tjondro HC, Zhao XJ, Luo H, Hou R, Perry JJ, Gao W, Kozak I, Granet D, Li Y, Sun X, Wang J, Zhang L, Liu Y, Yan YB, Zhang K. Corrigendum: Lanosterol reverses protein aggregation in cataracts. Nature. 2015 Oct 22;526(7574):595. doi: 10.1038/nature15253. Epub 2015 Aug 26. PMID: 26308894.
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Ascorbic acid attenuates the pressor response to voluntary apnea in postmenopausal women.

Physiological reports

Randolph BJ, Patel HM, Muller MD.
PMID: 25907792
Physiol Rep. 2015 Apr;3(4). doi: 10.14814/phy2.12384.

We recently demonstrated that postmenopausal women have an augmented blood pressure response to voluntary apnea compared to premenopausal women. Both obstructive sleep apnea (OSA) and healthy aging are associated with increased oxidative stress, which may impair cardiovascular function. Restoring...

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Randolph BJ, Patel HM, Muller MD. Ascorbic acid attenuates the pressor response to voluntary apnea in postmenopausal women. Physiol Rep. 2015;3(4)doi: 10.14814/phy2.12384.
Randolph, B. J., Patel, H. M., & Muller, M. D. (2015). Ascorbic acid attenuates the pressor response to voluntary apnea in postmenopausal women. Physiological reports, 3(4), . https://doi.org/10.14814/phy2.12384
Randolph, Brittney J, et al. "Ascorbic acid attenuates the pressor response to voluntary apnea in postmenopausal women." Physiological reports vol. 3,4 (2015). doi: https://doi.org/10.14814/phy2.12384
Randolph BJ, Patel HM, Muller MD. Ascorbic acid attenuates the pressor response to voluntary apnea in postmenopausal women. Physiol Rep. 2015 Apr;3(4). doi: 10.14814/phy2.12384. PMID: 25907792; PMCID: PMC4425983.
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Imprudent Gastro-protective Approach in Majority of Specialists' Clinics of a Tertiary Hospital.

Journal of clinical and diagnostic research : JCDR

Patel HR, Dhande P.
PMID: 27134889
J Clin Diagn Res. 2016 Mar;10(3):FC12-5. doi: 10.7860/JCDR/2016/16976.7499. Epub 2016 Mar 01.

INTRODUCTION: One out of four prescriptions in out-patient departments contains a gastro-protective drug (APUD) - PPI/ H2 Blockers/ Antacids/ Ulcer Protective's. These drugs should be prescribed only when there is a justified indication. To assess the prescriptions of gastro-protective...

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Patel HR, Dhande P. Imprudent Gastro-protective Approach in Majority of Specialists' Clinics of a Tertiary Hospital. J Clin Diagn Res. 2016;10(3):FC12-5doi: 10.7860/JCDR/2016/16976.7499.
Patel, H. R., & Dhande, P. (2016). Imprudent Gastro-protective Approach in Majority of Specialists' Clinics of a Tertiary Hospital. Journal of clinical and diagnostic research : JCDR, 10(3), FC12-5. https://doi.org/10.7860/JCDR/2016/16976.7499
Patel, Hardik Rameshbhai, and Dhande, Priti. "Imprudent Gastro-protective Approach in Majority of Specialists' Clinics of a Tertiary Hospital." Journal of clinical and diagnostic research : JCDR vol. 10,3 (2016): FC12-5. doi: https://doi.org/10.7860/JCDR/2016/16976.7499
Patel HR, Dhande P. Imprudent Gastro-protective Approach in Majority of Specialists' Clinics of a Tertiary Hospital. J Clin Diagn Res. 2016 Mar;10(3):FC12-5. doi: 10.7860/JCDR/2016/16976.7499. Epub 2016 Mar 01. PMID: 27134889; PMCID: PMC4843275.
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An overlooked case of pacemaker-related heart failure.

Echo research and practice

Patel HC, Mariani JA.
PMID: 29117988
Echo Res Pract. 2017 Dec;4(4):K57-K60. doi: 10.1530/ERP-17-0057. Epub 2017 Nov 08.

This case describes an iatrogenic cause of heart failure: the pacemaker syndrome. The diagnosis was initially overlooked but in retrospect could have easily been made by reviewing the rhythm strip recorded during the echocardiogram. The patient eventually received the...

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Patel HC, Mariani JA. An overlooked case of pacemaker-related heart failure. Echo Res Pract. 2017;4(4):K57-K60doi: 10.1530/ERP-17-0057.
Patel, H. C., & Mariani, J. A. (2017). An overlooked case of pacemaker-related heart failure. Echo research and practice, 4(4), K57-K60. https://doi.org/10.1530/ERP-17-0057
Patel, Hitesh C, and Mariani, Justin A. "An overlooked case of pacemaker-related heart failure." Echo research and practice vol. 4,4 (2017): K57-K60. doi: https://doi.org/10.1530/ERP-17-0057
Patel HC, Mariani JA. An overlooked case of pacemaker-related heart failure. Echo Res Pract. 2017 Dec;4(4):K57-K60. doi: 10.1530/ERP-17-0057. Epub 2017 Nov 08. PMID: 29117988; PMCID: PMC5682409.
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Economic burden of hospitalizations of Medicare beneficiaries with heart failure.

Risk management and healthcare policy

Kilgore M, Patel HK, Kielhorn A, Maya JF, Sharma P.
PMID: 28546776
Risk Manag Healthc Policy. 2017 May 10;10:63-70. doi: 10.2147/RMHP.S130341. eCollection 2017.

OBJECTIVE: The objective of this study was to assess the costs associated with the hospitalization and the cumulative 30-, 60-, and 90-day readmission rates in a cohort of Medicare beneficiaries with heart failure (HF).METHODS: This was a retrospective, observational...

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Kilgore M, Patel HK, Kielhorn A, et al. Economic burden of hospitalizations of Medicare beneficiaries with heart failure. Risk Manag Healthc Policy. 2017;10:63-70doi: 10.2147/RMHP.S130341.
Kilgore, M., Patel, H. K., Kielhorn, A., Maya, J. F., & Sharma, P. (2017). Economic burden of hospitalizations of Medicare beneficiaries with heart failure. Risk management and healthcare policy, 1063-70. https://doi.org/10.2147/RMHP.S130341
Kilgore, Meredith, et al. "Economic burden of hospitalizations of Medicare beneficiaries with heart failure." Risk management and healthcare policy vol. 10 (2017): 63-70. doi: https://doi.org/10.2147/RMHP.S130341
Kilgore M, Patel HK, Kielhorn A, Maya JF, Sharma P. Economic burden of hospitalizations of Medicare beneficiaries with heart failure. Risk Manag Healthc Policy. 2017 May 10;10:63-70. doi: 10.2147/RMHP.S130341. eCollection 2017. PMID: 28546776; PMCID: PMC5436769.
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Collapsing Glomerulopathy: A Single Centre Clinicopathologic Study of Seven Years.

Journal of clinical and diagnostic research : JCDR

Kanodia KV, Vanikar AV, Patel RD, Suthar KS, Nigam LK, Patel HV, Kute V, Trivedi HL.
PMID: 27190812
J Clin Diagn Res. 2016 Apr;10(4):EC15-7. doi: 10.7860/JCDR/2016/17297.7646. Epub 2016 Apr 01.

INTRODUCTION: Collapsing Glomerulopathy (CG) is recognized as distinct pattern of proliferative parenchymal injury with poor response to empirical therapy.AIM: A single center retrospective study was carried out to find out clinicopathological features of idiopathic CG.MATERIALS AND METHODS: A total...

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Kanodia KV, Vanikar AV, Patel RD, et al. Collapsing Glomerulopathy: A Single Centre Clinicopathologic Study of Seven Years. J Clin Diagn Res. 2016;10(4):EC15-7doi: 10.7860/JCDR/2016/17297.7646.
Kanodia, K. V., Vanikar, A. V., Patel, R. D., Suthar, K. S., Nigam, L. K., Patel, H. V., Kute, V., & Trivedi, H. L. (2016). Collapsing Glomerulopathy: A Single Centre Clinicopathologic Study of Seven Years. Journal of clinical and diagnostic research : JCDR, 10(4), EC15-7. https://doi.org/10.7860/JCDR/2016/17297.7646
Kanodia, Kamal V, et al. "Collapsing Glomerulopathy: A Single Centre Clinicopathologic Study of Seven Years." Journal of clinical and diagnostic research : JCDR vol. 10,4 (2016): EC15-7. doi: https://doi.org/10.7860/JCDR/2016/17297.7646
Kanodia KV, Vanikar AV, Patel RD, Suthar KS, Nigam LK, Patel HV, Kute V, Trivedi HL. Collapsing Glomerulopathy: A Single Centre Clinicopathologic Study of Seven Years. J Clin Diagn Res. 2016 Apr;10(4):EC15-7. doi: 10.7860/JCDR/2016/17297.7646. Epub 2016 Apr 01. PMID: 27190812; PMCID: PMC4866110.
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Posterior reversible encephalopathy syndrome-an under recognized manifestation of Chronic Kidney Disease.

Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

Kute VB, Trivedi HL, Shah PR, Gumber MR, Patel HV, Vanikar AV.
PMID: 24339647
Indian J Crit Care Med. 2013 Sep;17(5):318-20. doi: 10.4103/0972-5229.120329.

First Report of the Indian Chronic Kidney Disease (CKD) Registry showed that patient with CKD in India more frequently presented in Stage V. Many patients have uncontrolled hypertension and uremia due to noncompliance or non affordability of renal replacement...

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Kute VB, Trivedi HL, Shah PR, et al. Posterior reversible encephalopathy syndrome-an under recognized manifestation of Chronic Kidney Disease. Indian J Crit Care Med. 2013;17(5):318-20doi: 10.4103/0972-5229.120329.
Kute, V. B., Trivedi, H. L., Shah, P. R., Gumber, M. R., Patel, H. V., & Vanikar, A. V. (2013). Posterior reversible encephalopathy syndrome-an under recognized manifestation of Chronic Kidney Disease. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 17(5), 318-20. https://doi.org/10.4103/0972-5229.120329
Kute, Vivek B, et al. "Posterior reversible encephalopathy syndrome-an under recognized manifestation of Chronic Kidney Disease." Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine vol. 17,5 (2013): 318-20. doi: https://doi.org/10.4103/0972-5229.120329
Kute VB, Trivedi HL, Shah PR, Gumber MR, Patel HV, Vanikar AV. Posterior reversible encephalopathy syndrome-an under recognized manifestation of Chronic Kidney Disease. Indian J Crit Care Med. 2013 Sep;17(5):318-20. doi: 10.4103/0972-5229.120329. PMID: 24339647; PMCID: PMC3841498.
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Showing 1 to 12 of 1374 entries