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Showing 1 to 12 of 428 entries
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Large-scale gene relocations following an ancient genome triplication associated with the diversification of core eudicots

STEM and diversification

Feltus FA, Ficklin SP, Paterson AH, Wang Y.
GSID: xzvu366TAIAJ
Y Wang, SP Ficklin, X Wang, FA Feltus, AH Paterson - PloS one, 2016 - journals.plos.org

… triplication (γ) event that occurred in the stem lineage of core eudicots. We name these … relocations following the γ event were associated with the diversification of core eudicots. …

Sonographer registration in the United Kingdom - a review of the current situation.

Ultrasound (Leeds, England)

Thomson N, Paterson A.
PMID: 27433193
Ultrasound. 2014 Feb;22(1):52-6. doi: 10.1177/1742271X13517381. Epub 2013 Dec 20.

There is no statutory registration as a sonographer available in the United Kingdom (UK) and the titles of 'sonographer' and 'ultrasonographer' are not legally protected. The majority of sonographers are statutorily registered with the Health and Care Professions Council...

Introducing pharmacogenetic testing with clinical decision support into primary care: a feasibility study.

CMAJ open

Dawes M, Aloise MN, Ang JS, Cullis P, Dawes D, Fraser R, Liknaitzky G, Paterson A, Stanley P, Suarez-Gonzalez A, Katzov-Eckert H.
PMID: 27730116
CMAJ Open. 2016 Sep 21;4(3):E528-E534. doi: 10.9778/cmajo.20150070. eCollection 2016.

BACKGROUND: Inappropriate prescribing increases patient illness and death owing to adverse drug events. The inclusion of genetic information into primary care medication practices is one solution. Our aim was to assess the ability to obtain and genotype saliva samples...

Correction to: Outcomes of notifications to health practitioner boards: a retrospective cohort study.

BMC medicine

Spittal MJ, Studdert DM, Paterson R, Bismark MM.
PMID: 29514646
BMC Med. 2018 Mar 07;16(1):38. doi: 10.1186/s12916-018-1030-x.

The original article [1] contains a major error whereby all rates in Table 2 are mistakenly presented as 50% of their true values; this error was caused by a miscalculation in annualising the original values that represented the rates.

A global database of lake surface temperatures collected by in situ and satellite methods from 1985-2009.

Scientific data

Sharma S, Gray DK, Read JS, O'Reilly CM, Schneider P, Qudrat A, Gries C, Stefanoff S, Hampton SE, Hook S, Lenters JD, Livingstone DM, McIntyre PB, Adrian R, Allan MG, Anneville O, Arvola L, Austin J, Bailey J, Baron JS, Brookes J, Chen Y, Daly R, Dokulil M, Dong B, Ewing K, de Eyto E, Hamilton D, Havens K, Haydon S, Hetzenauer H, Heneberry J, Hetherington AL, Higgins SN, Hixson E, Izmest'eva LR, Jones BM, Kangur K, Kasprzak P, Köster O, Kraemer BM, Kumagai M, Kuusisto E, Leshkevich G, May L, MacIntyre S, Müller-Navarra D, Naumenko M, Noges P, Noges T, Niederhauser P, North RP, Paterson AM, Plisnier PD, Rigosi A, Rimmer A, Rogora M, Rudstam L, Rusak JA, Salmaso N, Samal NR, Schindler DE, Schladow G, Schmidt SR, Schultz T, Silow EA, Straile D, Teubner K, Verburg P, Voutilainen A, Watkinson A, Weyhenmeyer GA, Williamson CE, Woo KH.
PMID: 25977814
Sci Data. 2015 Mar 17;2:150008. doi: 10.1038/sdata.2015.8. eCollection 2015.

Global environmental change has influenced lake surface temperatures, a key driver of ecosystem structure and function. Recent studies have suggested significant warming of water temperatures in individual lakes across many different regions around the world. However, the spatial and...

Using a Bayesian latent variable approach to detect pleiotropy in the Genetic Analysis Workshop 18 data.

BMC proceedings

Xu L, Craiu RV, Derkach A, Paterson AD, Sun L.
PMID: 25519405
BMC Proc. 2014 Jun 17;8:S77. doi: 10.1186/1753-6561-8-S1-S77. eCollection 2014.

Pleiotropy, which occurs when a single genetic factor influences multiple phenotypes, is present in many genetic studies of complex human traits. Longitudinal family data, such as the Genetic Analysis Workshop 18 data, combine the features of longitudinal studies in...

Evaluation of gene-based association tests for analyzing rare variants using Genetic Analysis Workshop 18 data.

BMC proceedings

Derkach A, Lawless JF, Merico D, Paterson AD, Sun L.
PMID: 25519417
BMC Proc. 2014 Jun 17;8:S9. doi: 10.1186/1753-6561-8-S1-S9. eCollection 2014.

The focus of our work is to evaluate several recently developed pooled association tests for rare variants and assess the impact of different gene annotation methods and binning strategies on the analyses of rare variants under Genetic Analysis Workshop...

Recurrent stereotyped episodes in cerebral amyloid angiopathy: response to migraine prophylaxis in two patients.

Cerebrovascular diseases extra

Paterson RW, Uchino K, Emsley HC, Pullicino P.
PMID: 23741226
Cerebrovasc Dis Extra. 2013 May 18;3(1):81-4. doi: 10.1159/000347114. Print 2013 Jan.

BACKGROUND: Cerebral amyloid angiopathy (CAA) typically presents with cognitive decline or symptomatic intracerebral hemorrhage, but episodes of recurrent stereotyped limb attacks have also been reported.METHODS: Retrospective review of the medical records of 4 patients referred to the general neurology...

Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Samuel N, Wilson G, Lemire M, Id Said B, Lou Y, Li W, Merino D, Novokmet A, Tran J, Nichols KE, Finlay JL, Choufani S, Remke M, Ramaswamy V, Cavalli FMG, Elser C, Meister L, Taylor MD, Tabori U, Irwin M, Weksberg R, Wasserman JD, Paterson AD, Hansford JR, Achatz MIW, Hudson TJ, Malkin D.
PMID: 27551116
J Clin Oncol. 2016 Oct 20;34(30):3697-3704. doi: 10.1200/JCO.2016.67.6940.

PURPOSE: Although the link between mutant TP53 and human cancer is unequivocal, a significant knowledge gap exists in clinically actionable molecular targets in Li-Fraumeni syndrome (LFS), a highly penetrant cancer predisposition syndrome associated with germline mutations in TP53. This...

Using florbetapir positron emission tomography to explore cerebrospinal fluid cut points and gray zones in small sample sizes.

Alzheimer's & dementia (Amsterdam, Netherlands)

Weston PS, Paterson RW, Modat M, Burgos N, Cardoso MJ, Magdalinou N, Lehmann M, Dickson JC, Barnes A, Bomanji JB, Kayani I, Cash DM, Ourselin S, Toombs J, Lunn MP, Mummery CJ, Warren JD, Rossor MN, Fox NC, Zetterberg H, Schott JM.
PMID: 26835507
Alzheimers Dement (Amst). 2015 Nov 02;1(4):440-446. doi: 10.1016/j.dadm.2015.10.001. eCollection 2015 Dec.

INTRODUCTION: We aimed to assess the feasibility of determining Alzheimer's disease cerebrospinal fluid (CSF) cut points in small samples through comparison with amyloid positron emission tomography (PET).METHODS: Twenty-three individuals (19 patients, four controls) had CSF measures of amyloid beta...

Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families.

Journal of neurodevelopmental disorders

Woodbury-Smith M, Bilder DA, Morgan J, Jerominski L, Darlington T, Dyer T, Paterson AD, Coon H.
PMID: 28289475
J Neurodev Disord. 2017 Feb 13;9:5. doi: 10.1186/s11689-017-9187-8. eCollection 2017.

BACKGROUND: It has long been recognized that there is an association between enlarged head circumference (HC) and autism spectrum disorder (ASD), but the genetics of HC in ASD is not well understood. In order to investigate the genetic underpinning...

Model for cw laser collisionally induced fluorescence in low-temperature discharges.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Stewart RS, Smith DJ, Borthwick IS, Paterson AM.
PMID: 11088748
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000 Aug;62(2):2678-83. doi: 10.1103/physreve.62.2678.

A perturbed steady-state rate-equation model has been developed for the cw laser collisionally induced fluorescence (LCIF) produced by excitation on one of the 1s-2p noble gas transitions. This work is one part of a wider complementary modeling program which...

Showing 1 to 12 of 428 entries