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Der(16)T(1-16) is a nonrandom secondary chromosome aberration in many types of human neoplasia, including myxoid liposarcoma, rhabdomyosarcoma and Philadelphia-chromosome-positive acute lymphoblastic-leukemia.

International journal of oncology

Mrozek K, Arthur D, Karakousis C, Koduru P, Lebeau M, Pettenati M, Tantravahi R, Mrozek E, Perezmesa C, Rao U, Frankel S, Davey F, Bloomfield C.
PMID: 21556567
Int J Oncol. 1995 Mar;6(3):531-8. doi: 10.3892/ijo.6.3.531.

An unbalanced translocation between chromosomes 1 and 16, der(16)t(1;16), resulting in trisomy 1q and loss of genetic material from 16q, has been thus far suggested to constitute a nonrandom secondary abnormality in two types of closely related solid tumors...

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