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Showing 1 to 12 of 282 entries
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Guideline for the diagnosis of drug hypersensitivity reactions: S2K-Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) and the German Dermatological Society (DDG) in collaboration with the Association of German Allergologists (AeDA), the German Society for Pediatric Allergology and Environmental Medicine (GPA), the German Contact Dermatitis Research Group (DKG), the Swiss Society for Allergy and Immunology (SGAI), the Austrian Society for Allergology and Immunology (.

Allergo journal international

Brockow K, Przybilla B, Aberer W, Bircher AJ, Brehler R, Dickel H, Fuchs T, Jakob T, Lange L, Pfützner W, Mockenhaupt M, Ott H, Pfaar O, Ring J, Sachs B, Sitter H, Trautmann A, Treudler R, Wedi B, Worm M, Wurpts G, Zuberbier T, Merk HF.
PMID: 26120552
Allergo J Int. 2015;24(3):94-105. doi: 10.1007/s40629-015-0052-6.

Drug hypersensitivity reactions are unpredictable adverse drug reactions. They manifest either within 1-6 h following drug intake (immediate reactions) with mild to life-threatening symptoms of anaphylaxis, or several hours to days later (delayed reactions), primarily as exanthematous eruptions. It...

Evidence vs. efficacy in allergen-specific immunotherapy: Considerations using the example of tradable products in Germany.

Allergo journal international

Brehler R, Klimek L, Vogelberg C, Werfel T, Pfaar O, Hamelmann E.
PMID: 27226950
Allergo J Int. 2016;25:38-43. doi: 10.1007/s40629-016-0096-2. Epub 2016 Mar 23.

The recently published S2k-guideline on (allergen-) specific immunotherapy (AIT) provides an excellent overview of the evidence on allergen preparations available for AIT in Germany based on the published efficacy studies. Publications based on the guideline are currently being used...

Allergen immunotherapy for allergic asthma: protocol for a systematic review.

Clinical and translational allergy

Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A.
PMID: 26862389
Clin Transl Allergy. 2016 Feb 09;6:5. doi: 10.1186/s13601-016-0094-y. eCollection 2015.

BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for Allergic Asthma. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in...

Overlapping of two truncated crisis scenarios: generator of peaks in mean lifetimes of chaotic transients.

Physical review. E, Statistical, nonlinear, and soft matter physics

Paar V, Pavin N.
PMID: 14524883
Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Sep;68(3):036222. doi: 10.1103/PhysRevE.68.036222. Epub 2003 Sep 30.

Maxima of mean transient time versus driving amplitude were found for weakly dissipated Duffing oscillator. In the neighborhood of peak of mean transient time an approximate power-law dependence was found. This behavior was compared with scaling in the vicinity...

Spin-isospin resonances and the neutron skin of nuclei.

Physical review letters

Vretenar D, Paar N, Niksić T, Ring P.
PMID: 14754046
Phys Rev Lett. 2003 Dec 31;91(26):262502. doi: 10.1103/PhysRevLett.91.262502. Epub 2003 Dec 29.

The Gamow-Teller resonances (GTR) and isobaric analog states (IAS) of a sequence of even-even Sn target nuclei are calculated by using the framework of the relativistic Hartree-Bogoliubov model plus proton-neutron quasiparticle random-phase approximation. The calculation reproduces the experimental data...

Diabetes-induced fetal growth retardation is associated with suppression of NF-kappaB activity in embryos.

The review of diabetic studies : RDS

Mammon K, Keshet R, Savion S, Pekar O, Zaslavsky Z, Fein A, Toder V, Torchinsky A.
PMID: 17491656
Rev Diabet Stud. 2005;2(1):27-34. doi: 10.1900/RDS.2005.2.27. Epub 2005 May 10.

BACKGROUND: Mechanisms underlying diabetes-induced fetal growth retardation remain largely undefined. Two events such as the persistent activation of apoptosis or suppression of cell proliferation in embryos might directly result in fetal growth retardation. Evidence implicating the transcription factor NF-kappaB...

[Introduction of new laboratory methods].

Casopis lekaru ceskych

PIHAR O, MINICHBAUER K, MIKETUKOVA V.
PMID: 18140628
Cas Lek Cesk. 1949 Aug 26;88(34):979-81.

No abstract available.

Probability densities for the sums of iterates of the sine-circle map in the vicinity of the quasiperiodic edge of chaos.

Physical review. E, Statistical, nonlinear, and soft matter physics

Afsar O, Tirnakli U.
PMID: 21230368
Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Oct;82(4):046210. doi: 10.1103/PhysRevE.82.046210. Epub 2010 Oct 11.

We investigate the probability density of rescaled sum of iterates of sine-circle map within quasiperiodic route to chaos. When the dynamical system is strongly mixing (i.e., ergodic), standard central limit theorem (CLT) is expected to be valid, but at...

Isospin mass splittings from precision measurements of D*-D mass differences.

Physical review letters

Acosta D, Akerib DS, Artuso M, Barish B, Barnes AV, Bartelt J, Battle M, Bean A, Bortoletto D, Brown DN, Chadha M, Cowen DF, Csorna SE, Dominick J, Egyed Z, Eigen G, Ernst J, Goldberg M, Gronberg J, Horwitz N, Jain V, Kennett R, Kroha H, Kutschke R, Masek G, McIlwain RL, Menary S, Miao T, Miller DH, Miller JS, Modesitt M, Moneti GC, Morrison RJ, Muheim F, Nelson H, Ong B, Paar H, Playfer S, Procario M, Richman J, Roberts S, Rozen Y, Rubin P, Sanghera S, Schaffner SF, Schmidt D, Sheldon P, Shibata EI, Shipsey IP, Sivertz M, Skwarnicki T, Sparks K, Sperka D, Stone S, Stroynowski R, Tajima H, Thorndike EH, Thulasidas M, Urheim J, Wang C, Weinstein AJ, Witherell M, Yao W, Zhu G.
PMID: 10046385
Phys Rev Lett. 1992 Oct 05;69(14):2046-2049. doi: 10.1103/PhysRevLett.69.2046.

No abstract available.

Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation.

Oncogenesis

Xu J, Pfarr N, Endris V, Mai EK, Md Hanafiah NH, Lehners N, Penzel R, Weichert W, Ho AD, Schirmacher P, Goldschmidt H, Andrulis M, Raab MS.
PMID: 28504689
Oncogenesis. 2017 May 15;6(5):e337. doi: 10.1038/oncsis.2017.36.

Multiple myeloma (MM) is a plasma cell malignancy that is still considered to be incurable in most cases. A dominant mutation cluster has been identified in RAS/RAF genes, emphasizing the potential significance of RAS/RAF/MEK/ERK signaling as a therapeutic target....

[Guideline for the Diagnosis and Treatment of Asthma - Guideline of the German Respiratory Society and the German Atemwegsliga in Cooperation with the Paediatric Respiratory Society and the Austrian Society of Pneumology].

Pneumologie (Stuttgart, Germany)

Buhl R, Bals R, Baur X, Berdel D, Criée CP, Gappa M, Gillissen A, Greulich T, Haidl P, Hamelmann E, Kardos P, Kenn K, Klimek L, Korn S, Lommatzsch M, Magnussen H, Nicolai T, Nowak D, Pfaar O, Rabe KF, Riedler J, Ritz T, Schultz K, Schuster A, Spindler T, Taube C, Taube K, Vogelmeier C, von Leupoldt A, Wantke F, Weise S, Wildhaber J, Worth H, Zacharasiewicz A.
PMID: 30406626
Pneumologie. 2017 Dec;71(12):e3. doi: 10.1055/a-0790-0021. Epub 2018 Nov 07.

No abstract available.

Effect of Linagliptin vs Glimepiride on Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes: The CAROLINA Randomized Clinical Trial.

JAMA

Rosenstock J, Kahn SE, Johansen OE, Zinman B, Espeland MA, Woerle HJ, Pfarr E, Keller A, Mattheus M, Baanstra D, Meinicke T, George JT, von Eynatten M, McGuire DK, Marx N.
PMID: 31536101
JAMA. 2019 Sep 24;322(12):1155-1166. doi: 10.1001/jama.2019.13772.

IMPORTANCE: Type 2 diabetes is associated with increased cardiovascular risk. In placebo-controlled cardiovascular safety trials, the dipeptidyl peptidase-4 inhibitor linagliptin demonstrated noninferiority, but it has not been tested against an active comparator.OBJECTIVE: This trial assessed cardiovascular outcomes of linagliptin...

Showing 1 to 12 of 282 entries