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Dhami S, Nurmatov U, Agache I, et al. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2016;6:5doi: 10.1186/s13601-016-0094-y.
Dhami, S., Nurmatov, U., Agache, I., Lau, S., Muraro, A., Jutel, M., Roberts, G., Akdis, C., Bonini, M., Calderon, M., Casale, T., Cavkaytar, O., Cox, L., Demoly, P., Flood, B., Hamelmann, E., Izuhara, K., Kalayci, �. �., Kleine-Tebbe, J., Nieto, A., Papadopoulos, N., Pfaar, O., Rosenwasser, L., Ryan, D., Schmidt-Weber, C., Szefler, S., Wahn, U., van Wijk, R. G., Wilkinson, J., & Sheikh, A. (2015). Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clinical and translational allergy, 65. https://doi.org/10.1186/s13601-016-0094-y
Dhami, Sangeeta, et al. "Allergen immunotherapy for allergic asthma: protocol for a systematic review." Clinical and translational allergy vol. 6 (2015): 5. doi: https://doi.org/10.1186/s13601-016-0094-y
Dhami S, Nurmatov U, Agache I, Lau S, Muraro A, Jutel M, Roberts G, Akdis C, Bonini M, Calderon M, Casale T, Cavkaytar O, Cox L, Demoly P, Flood B, Hamelmann E, Izuhara K, Kalayci Ö, Kleine-Tebbe J, Nieto A, Papadopoulos N, Pfaar O, Rosenwasser L, Ryan D, Schmidt-Weber C, Szefler S, Wahn U, van Wijk RG, Wilkinson J, Sheikh A. Allergen immunotherapy for allergic asthma: protocol for a systematic review. Clin Transl Allergy. 2016 Feb 09;6:5. doi: 10.1186/s13601-016-0094-y. eCollection 2015. PMID: 26862389; PMCID: PMC4746770.
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Clin Transl Allergy. 2016 Feb 09;6:5. doi: 10.1186/s13601-016-0094-y. eCollection 2015.

Allergen immunotherapy for allergic asthma: protocol for a systematic review.

Clinical and translational allergy

Sangeeta Dhami, Ulugbek Nurmatov, Ioana Agache, Susanne Lau, Antonella Muraro, Marek Jutel, Graham Roberts, Cezmi Akdis, Matteo Bonini, Moises Calderon, Thomas Casale, Ozlem Cavkaytar, Linda Cox, Pascal Demoly, Breda Flood, Eckard Hamelmann, Kenji Izuhara, Ömer Kalayci, Jörg Kleine-Tebbe, Antonio Nieto, Nikolaos Papadopoulos, Oliver Pfaar, Lanny Rosenwasser, Dermot Ryan, Carsten Schmidt-Weber, Stan Szefler, Ulrich Wahn, Roy-Gerth van Wijk, Jamie Wilkinson, Aziz Sheikh

Affiliations

  1. Evidence-Based Health Care Ltd, Edinburgh, UK.
  2. Systematic Review at Decision Resources Group Abacus International, Oxford, UK.
  3. Department of Allergy and Clinical Immunology, Faculty of Medicine, Transylvania University Brasov, Brasov, Romania.
  4. Department of Pediatric Pneumology and Immunology, Charité Medical University, Berlin, Germany.
  5. Food Allergy Referral Centre Veneto Region, University Hospital of Padua, Padua, Italy.
  6. Wroclaw Medical University, Wroc?aw, Poland.
  7. The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport Isle of Wight, NIHR Respiratory Biomedical Research Unit, University Hospital Southampton NHS Foundation Trust, Southampton, UK ; Faculty of Medicine, University of Southampton, Southampton, UK.
  8. Swiss Institute for Allergy and Asthma Research, Davos, Switzerland.
  9. Sapienza University Rome, Rome, Italy.
  10. National Heart and Lung Institute, Imperial College, London, London, UK.
  11. University of South Florida, Tampa, FL USA.
  12. Department of Allegy and Clinical Immunology, Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey.
  13. Nova Southeastern University, Fort Lauderdale, FL USA.
  14. University and Hospital of Montpellier and Inserm Paris Sorbonnes, Montpellier, France.
  15. European Federation of Allergy and Airways Diseases Patients Association, Brussels, Belgium.
  16. Children's Center Bethel, EvKB, Bieledelf, Germany ; Allergy Center, Ruhr-University, Bochum, Germany.
  17. Saga Medical School, Saga, Japan.
  18. Hacettepe University, Ankara, Turkey.
  19. Allergy and Asthma Center Westend (AAZW), Berlin, Germany.
  20. Children's Hospital La Fe, Valencia, Spain.
  21. Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece.
  22. Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Mannheim, Mannheim, Germany ; Center for Rhinology and Allergology, Wiesbaden, Germany.
  23. Children's Mercy Hospital, Kentucky, MO USA.
  24. University of Edinburgh, Edinburgh, UK.
  25. Technische Univ and Helmholtz Center Munich, Munich, Germany.
  26. Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO USA.
  27. Department of Pediatric Pulmonology, Charite, Berlin, Germany.
  28. Section of Allergology, Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.
  29. Pharmaceutical Group of the European Union, Brussels, Belgium.
  30. Allergy and Respiratory Research Group, The University of Edinburgh, Edinburgh, UK.

PMID: 26862389 PMCID: PMC4746770 DOI: 10.1186/s13601-016-0094-y

Abstract

BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for Allergic Asthma. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of allergic asthma.

METHODS: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.

DISCUSSION: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

Keywords: Allergen immunotherapy; Allergic asthma; Allergy; Disease-modifying; Respiratory allergy

References

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