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Showing 1 to 7 of 7 entries
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Mitochondrial H2O2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons.

Journal of molecular signaling

Persiyantseva NA, Storozhevykh TP, Senilova YE, Gorbacheva LR, Pinelis VG, Pomytkin IA.
PMID: 24094269
J Mol Signal. 2013 Oct 05;8(1):11. doi: 10.1186/1750-2187-8-11.

BACKGROUND: Insulin receptors are widely distributed in the brain, where they play roles in synaptic function, memory formation, and neuroprotection. Autophosphorylation of the receptor in response to insulin stimulation is a critical step in receptor activation. In neurons, insulin...

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Persiyantseva NA, Storozhevykh TP, Senilova YE, et al. Mitochondrial H2O2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons. J Mol Signal. 2013;8(1):11doi: 10.1186/1750-2187-8-11.
Persiyantseva, N. A., Storozhevykh, T. P., Senilova, Y. E., Gorbacheva, L. R., Pinelis, V. G., & Pomytkin, I. A. (2013). Mitochondrial H2O2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons. Journal of molecular signaling, 8(1), 11. https://doi.org/10.1186/1750-2187-8-11
Persiyantseva, Nadezhda A, et al. "Mitochondrial H2O2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons." Journal of molecular signaling vol. 8,1 (2013): 11. doi: https://doi.org/10.1186/1750-2187-8-11
Persiyantseva NA, Storozhevykh TP, Senilova YE, Gorbacheva LR, Pinelis VG, Pomytkin IA. Mitochondrial H2O2 as an enable signal for triggering autophosphorylation of insulin receptor in neurons. J Mol Signal. 2013 Oct 05;8(1):11. doi: 10.1186/1750-2187-8-11. PMID: 24094269; PMCID: PMC3817577.
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Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions.

Life (Basel, Switzerland)

Pomytkin I, Pinelis V.
PMID: 33810179
Life (Basel). 2021 Mar 22;11(3). doi: 10.3390/life11030262.

Current hypotheses implicate insulin resistance of the brain as a pathogenic factor in the development of Alzheimer's disease and other dementias, Parkinson's disease, type 2 diabetes, obesity, major depression, and traumatic brain injury. A variety of genetic, developmental, and...

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Pomytkin I, Pinelis V. Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions. Life (Basel). 2021;11(3)doi: 10.3390/life11030262.
Pomytkin, I., & Pinelis, V. (2021). Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions. Life (Basel, Switzerland), 11(3), . https://doi.org/10.3390/life11030262
Pomytkin, Igor, and Pinelis, Vsevolod. "Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions." Life (Basel, Switzerland) vol. 11,3 (2021). doi: https://doi.org/10.3390/life11030262
Pomytkin I, Pinelis V. Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions. Life (Basel). 2021 Mar 22;11(3). doi: 10.3390/life11030262. PMID: 33810179; PMCID: PMC8005009.
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On dimensionality, sample size, classification error, and complexity of classification algorithm in pattern recognition.

IEEE transactions on pattern analysis and machine intelligence

Raudys S, Pikelis V.
PMID: 21868897
IEEE Trans Pattern Anal Mach Intell. 1980 Mar;2(3):242-52. doi: 10.1109/tpami.1980.4767011.

This paper compares four classification algorithms-discriminant functions when classifying individuals into two multivariate populations. The discriminant functions (DF's) compared are derived according to the Bayes rule for normal populations and differ in assumptions on the covariance matrices' structure. Analytical...

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Raudys S, Pikelis V. On dimensionality, sample size, classification error, and complexity of classification algorithm in pattern recognition. IEEE Trans Pattern Anal Mach Intell. 1980;2(3):242-52doi: 10.1109/tpami.1980.4767011.
Raudys, S., & Pikelis, V. (1980). On dimensionality, sample size, classification error, and complexity of classification algorithm in pattern recognition. IEEE transactions on pattern analysis and machine intelligence, 2(3), 242-52. https://doi.org/10.1109/tpami.1980.4767011
Raudys, S, and Pikelis, V. "On dimensionality, sample size, classification error, and complexity of classification algorithm in pattern recognition." IEEE transactions on pattern analysis and machine intelligence vol. 2,3 (1980): 242-52. doi: https://doi.org/10.1109/tpami.1980.4767011
Raudys S, Pikelis V. On dimensionality, sample size, classification error, and complexity of classification algorithm in pattern recognition. IEEE Trans Pattern Anal Mach Intell. 1980 Mar;2(3):242-52. doi: 10.1109/tpami.1980.4767011. PMID: 21868897.
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[The International Baikal seminar 'Innovations in neurology and neurosurgery'-2015'].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova

Aleksandrova EV, Pinelis VG, Martynov MY, Skoromets AA.
PMID: 28635715
Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(1):122-124. doi: 10.17116/jnevro201611611122-124.

No abstract available.

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Aleksandrova EV, Pinelis VG, Martynov MY, et al. Mezhdunarodnyĭ Baĭkal'skiĭ seminar 'Innovatsii v nevrologii i neĭrokhirurgii-2015'. [The International Baikal seminar 'Innovations in neurology and neurosurgery'-2015']. Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(1):122-124doi: 10.17116/jnevro201611611122-124.
Aleksandrova, E. V., Pinelis, V. G., Martynov, M. Y., & Skoromets, A. A. (2016). Mezhdunarodnyĭ Baĭkal'skiĭ seminar 'Innovatsii v nevrologii i neĭrokhirurgii-2015'. [The International Baikal seminar 'Innovations in neurology and neurosurgery'-2015']. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 116(1), 122-124. https://doi.org/10.17116/jnevro201611611122-124
Aleksandrova, E V, et al. "Mezhdunarodnyĭ Baĭkal'skiĭ seminar 'Innovatsii v nevrologii i neĭrokhirurgii-2015'." [The International Baikal seminar 'Innovations in neurology and neurosurgery'-2015']. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova vol. 116,1 (2016): 122-124. doi: https://doi.org/10.17116/jnevro201611611122-124
Aleksandrova EV, Pinelis VG, Martynov MY, Skoromets AA. Mezhdunarodnyĭ Baĭkal'skiĭ seminar 'Innovatsii v nevrologii i neĭrokhirurgii-2015'. [The International Baikal seminar 'Innovations in neurology and neurosurgery'-2015']. Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(1):122-124. doi: 10.17116/jnevro201611611122-124. Russian. PMID: 28635715.
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Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures.

Frontiers in molecular neuroscience

Surin AM, Khiroug S, Gorbacheva LR, Khodorov BI, Pinelis VG, Khiroug L.
PMID: 23335879
Front Mol Neurosci. 2013 Jan 10;5:102. doi: 10.3389/fnmol.2012.00102. eCollection 2012.

ATP in neurons is commonly believed to be synthesized mostly by mitochondria via oxidative phosphorylation. Neuronal mitochondria have been studied primarily in culture, i.e., in neurons isolated either from embryos or from neonatal pups. Although it is generally assumed...

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Surin AM, Khiroug S, Gorbacheva LR, et al. Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures. Front Mol Neurosci. 2013;5:102doi: 10.3389/fnmol.2012.00102.
Surin, A. M., Khiroug, S., Gorbacheva, L. R., Khodorov, B. I., Pinelis, V. G., & Khiroug, L. (2012). Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures. Frontiers in molecular neuroscience, 5102. https://doi.org/10.3389/fnmol.2012.00102
Surin, Alexander M, et al. "Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures." Frontiers in molecular neuroscience vol. 5 (2012): 102. doi: https://doi.org/10.3389/fnmol.2012.00102
Surin AM, Khiroug S, Gorbacheva LR, Khodorov BI, Pinelis VG, Khiroug L. Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures. Front Mol Neurosci. 2013 Jan 10;5:102. doi: 10.3389/fnmol.2012.00102. eCollection 2012. PMID: 23335879; PMCID: PMC3541538.
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Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity.

Frontiers in neuroscience

Krasil'nikova I, Surin A, Sorokina E, Fisenko A, Boyarkin D, Balyasin M, Demchenko A, Pomytkin I, Pinelis V.
PMID: 31611766
Front Neurosci. 2019 Sep 24;13:1027. doi: 10.3389/fnins.2019.01027. eCollection 2019.

Glutamate excitotoxicity is implicated in the pathogenesis of numerous diseases, such as stroke, traumatic brain injury, and Alzheimer's disease, for which insulin resistance is a concomitant condition, and intranasal insulin treatment is believed to be a promising therapy. Excitotoxicity...

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Krasil'nikova I, Surin A, Sorokina E, et al. Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity. Front Neurosci. 2019;13:1027doi: 10.3389/fnins.2019.01027.
Krasil'nikova, I., Surin, A., Sorokina, E., Fisenko, A., Boyarkin, D., Balyasin, M., Demchenko, A., Pomytkin, I., & Pinelis, V. (2019). Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity. Frontiers in neuroscience, 131027. https://doi.org/10.3389/fnins.2019.01027
Krasil'nikova, Irina, et al. "Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity." Frontiers in neuroscience vol. 13 (2019): 1027. doi: https://doi.org/10.3389/fnins.2019.01027
Krasil'nikova I, Surin A, Sorokina E, Fisenko A, Boyarkin D, Balyasin M, Demchenko A, Pomytkin I, Pinelis V. Insulin Protects Cortical Neurons Against Glutamate Excitotoxicity. Front Neurosci. 2019 Sep 24;13:1027. doi: 10.3389/fnins.2019.01027. eCollection 2019. PMID: 31611766; PMCID: PMC6769071.
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Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital.

Cureus

Capone S, Abramyan S, Ross B, Rosenberg J, Zeibeq J, Vasudevan V, Samad R, Gerolemou L, Pinelis E, Gasperino J, Orsini J.
PMID: 32850261
Cureus. 2020 Aug 17;12(8):e9809. doi: 10.7759/cureus.9809.

Background The novel coronavirus disease 2019 (COVID-19) pandemic continues to spread across the country with over 3 million cases and 150,000 deaths in the United States as of July 2020. Outcomes have been poor, with reported admission rates to...

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Capone S, Abramyan S, Ross B, et al. Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital. Cureus. 2020;12(8):e9809doi: 10.7759/cureus.9809.
Capone, S., Abramyan, S., Ross, B., Rosenberg, J., Zeibeq, J., Vasudevan, V., Samad, R., Gerolemou, L., Pinelis, E., Gasperino, J., & Orsini, J. (2020). Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital. Cureus, 12(8), e9809. https://doi.org/10.7759/cureus.9809
Capone, Stephen, et al. "Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital." Cureus vol. 12,8 (2020): e9809. doi: https://doi.org/10.7759/cureus.9809
Capone S, Abramyan S, Ross B, Rosenberg J, Zeibeq J, Vasudevan V, Samad R, Gerolemou L, Pinelis E, Gasperino J, Orsini J. Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital. Cureus. 2020 Aug 17;12(8):e9809. doi: 10.7759/cureus.9809. PMID: 32850261; PMCID: PMC7444967.
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Showing 1 to 7 of 7 entries