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Showing 1 to 12 of 42 entries
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Small bowel malignancy in patients undergoing capsule endoscopy at a tertiary care academic center: Case series and review of the literature.

Endoscopy international open

Johnston CA, Yung DE, Joshi A, Plevris JN, Koulaouzidis A.
PMID: 28573179
Endosc Int Open. 2017 Jun;5(6):E463-E470. doi: 10.1055/s-0043-106186. Epub 2017 May 31.

BACKGROUND AND STUDY AIMS : Small bowel cancer is rare, accounting for

Argon plasma coagulation compared with stent placement in the palliative treatment of inoperable oesophageal cancer.

United European gastroenterology journal

Sigounas DE, Krystallis C, Couper G, Paterson-Brown S, Tatsioni A, Plevris JN.
PMID: 28405318
United European Gastroenterol J. 2017 Feb;5(1):21-31. doi: 10.1177/2050640616650786. Epub 2016 Jun 23.

BACKGROUND: Self-expandable metal stents (SEMSs) are the main palliative modality used in inoperable oesophageal cancer. Other palliative modalities, including argon plasma coagulation (APC), have also been used.OBJECTIVE: The purpose of this study was to assess the relative efficacy of...

Colon capsule endoscopy for detection of polyps and cancers: a step closer to non-invasive colon screening?.

The journal of the Royal College of Physicians of Edinburgh

Koulaouzidis A, Plevris JN.
PMID: 21677917
J R Coll Physicians Edinb. 2011 Jun;41(2):124-5. doi: 10.4997/JRCPE.2011.223.

No abstract available.

Letter to the editor: 'Human based systems: Mechanistic NASH modelling just around the corner?'.

Pharmacological research

Morgan K, Fassoula V, Samuel K, Morley SD, Hayes PC, Plevris JN.
PMID: 30315964
Pharmacol Res. 2018 Nov;137:280-281. doi: 10.1016/j.phrs.2018.09.028. Epub 2018 Oct 10.

No abstract available.

Response.

Gastrointestinal endoscopy

Yung DE, Koulaouzidis A, Plevris JN.
PMID: 28826556
Gastrointest Endosc. 2017 Sep;86(3):575. doi: 10.1016/j.gie.2017.05.020.

No abstract available.

Real-world experience with tofacitinib in ulcerative colitis: a systematic review and meta-analysis.

Therapeutic advances in gastroenterology

Lucaciu LA, Constantine-Cooke N, Plevris N, Siakavellas S, Derikx LAAP, Jones GR, Lees CW.
PMID: 34987608
Therap Adv Gastroenterol. 2021 Dec 23;14:17562848211064004. doi: 10.1177/17562848211064004. eCollection 2021.

BACKGROUND AND AIMS: Tofacitinib is a Janus kinase inhibitor (JAKi) recently approved for the treatment of moderate to severe ulcerative colitis (UC) based on robust efficacy and safety data derived from OCTAVE clinical trials. Evidence on the outcomes of...

Effectiveness and Safety of Adalimumab Biosimilar SB5 in Inflammatory Bowel Disease: Outcomes in Originator to SB5 Switch, Double Biosimilar Switch and Bio-Naïve SB5 Observational Cohorts.

Journal of Crohn's & colitis

Derikx LAAP, Dolby HW, Plevris N, Lucaciu L, Rees CS, Lyons M, Siakavellas SI, Constantine-Cooke N, Jenkinson P, Su S, O'Hare C, Kirckpatrick L, Merchant LM, Noble C, Arnott ID, Jones GR, Lees CW.
PMID: 34089587
J Crohns Colitis. 2021 Dec 18;15(12):2011-2021. doi: 10.1093/ecco-jcc/jjab100.

BACKGROUND AND AIMS: Multiple adalimumab [ADA] biosimilars are now approved for use in inflammatory bowel disease [IBD]; however, effectiveness and safety data remain scarce. We aimed to investigate long-term outcomes of the ADA biosimilar SB5 in IBD patients following...

SARS-CoV-2 Infection and the Liver.

Pathogens (Basel, Switzerland)

Morgan K, Samuel K, Vandeputte M, Hayes PC, Plevris JN.
PMID: 32486188
Pathogens. 2020 May 30;9(6). doi: 10.3390/pathogens9060430.

A novel strain of coronoviridae (SARS-CoV-2) was reported in Wuhan China in December 2019. Initially, infection presented with a broad spectrum of symptoms which typically included muscle aches, fever, dry cough, and shortness of breath. SARS-CoV-2 enters cells via...

Poor Quality of Small Bowel Capsule Endoscopy Images Has a Significant Negative Effect in the Diagnosis of Small Bowel Malignancy.

Clinical and experimental gastroenterology

Yung DE, Plevris JN, Leenhardt R, Dray X, Koulaouzidis A.
PMID: 33116745
Clin Exp Gastroenterol. 2020 Oct 21;13:475-484. doi: 10.2147/CEG.S260906. eCollection 2020.

BACKGROUND AND AIMS: Capsule endoscopy (CE) is a visual modality; hence, diagnosis relies on image quality. We studied the contribution of image parameters to visualization quality and their effect on diagnostic certainty of small bowel (SB) lesions.METHODS: Five clear...

The ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: A Simple Clinical Index on Admission that Predicts Outcome in Patients With Acute Ulcerative Colitis.

Inflammatory bowel diseases

Grant RK, Jones GR, Plevris N, Lynch RW, Jenkinson PW, Lees CW, Manship TA, Jagger FAM, Brindle WM, Shivakumar M, Satsangi J, Arnott IDR.
PMID: 32572468
Inflamm Bowel Dis. 2021 Mar 15;27(4):451-457. doi: 10.1093/ibd/izaa088.

BACKGROUND: Intravenous (IV) steroids remain the first-line treatment for patients with acute ulcerative colitis (UC). However, 30% of patients do not respond to steroids, requiring second-line therapy and/or surgery. There are no existing indices that allow physicians to predict...

Application of Impedance-Based Techniques in Hepatology Research.

Journal of clinical medicine

Morgan K, Gamal W, Samuel K, Morley SD, Hayes PC, Bagnaninchi P, Plevris JN.
PMID: 31878354
J Clin Med. 2019 Dec 24;9(1). doi: 10.3390/jcm9010050.

There are a variety of end-point assays and techniques available to monitor hepatic cell cultures and study toxicity within in vitro models. These commonly focus on one aspect of cell metabolism and are often destructive to cells. Impedance-based cellular...

Frontiers of Robotic Gastroscopy: A Comprehensive Review of Robotic Gastroscopes and Technologies.

Cancers

Marlicz W, Ren X, Robertson A, Skonieczna-Żydecka K, Łoniewski I, Dario P, Wang S, Plevris JN, Koulaouzidis A, Ciuti G.
PMID: 32998213
Cancers (Basel). 2020 Sep 28;12(10). doi: 10.3390/cancers12102775.

Upper gastrointestinal (UGI) tract pathology is common worldwide. With recent advancements in robotics, innovative diagnostic and treatment devices have been developed and several translational attempts made. This review paper aims to provide a highly pictorial critical review of robotic...

Showing 1 to 12 of 42 entries