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Showing 1 to 12 of 28 entries
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[Correlation of Endothelial Dysfunction With Course of Essential Arterial hypertension in Adolescence].

Kardiologiia

Plotnikova IV, Kovalev IA, Suslova TE, Bezlyak VV.
PMID: 28294839
Kardiologiia. 2015 Mar;55(3):21-26.

AIM: to study laboratory parameters of endothelial dysfunction (ED) and their correlation with risk factors (RF) of cardiovascular diseases at early stages of essential arterial hypertension (AH) in adolescents.MATERIAL AND METHODS: We examined 299 adolescents aged 12 - 18...

[Chronaximetric investigations in sequelae of poliomyelitis].

Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta

PLOTNIKOVA OV.
PMID: 13455755
Tr Leningr Sanitarnogig Med Inst. 1956;29:197-202.

No abstract available.

[Polymorphism of the bphA genes in bacteria destructing biphenyl/chlorinated biphenils].

Molekuliarnaia biologiia

Shumkova ES, Egorova DO, Boronnikova SV, Plotnikova EG.
PMID: 26299864
Mol Biol (Mosk). 2015 Jul-Aug;49(4):638-48. doi: 10.7868/S0026898415040151.

Polychlorinated biphenyls (PCBs) are persistent organic pollutants. Biphenyl 2,3-dioxygenase (BDO) is a key enzyme that determines the range of PCBs oxidized by a bacterial strain. BDO subunit α (BphA1) plays an essential role in substrate recognition and binding. The...

[Experience in the organization of a laboratory of centralized sterilization].

Fel'dsher i akusherka

Mikhaliuk VP, Plotnikova AT, Blokhinova AV.
PMID: 5203002
Feldsher Akush. 1970 Sep;35(9):3-6.

No abstract available.

Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.

Oncotarget

Grigorenko AP, Moliaka YK, Plotnikova OV, Smirnov A, Nikishina VA, Goltsov AY, Gusev F, Andreeva TV, Nelson O, Bezprozvanny I, Rogaev EI.
PMID: 29137240
Oncotarget. 2017 May 30;8(47):82006-82026. doi: 10.18632/oncotarget.18299. eCollection 2017 Oct 10.

The intramembrane proteolytic activities of presenilins (PSEN1/PS1 and PSEN2/PS2) underlie production of β-amyloid, the key process in Alzheimer's disease (AD). Dysregulation of presenilin-mediated signaling is linked to cancers. Inhibition of the γ-cleavage activities of PSENs that produce Aβ, but...

Compound phenotype in a girl with r(22), concomitant microdeletion 22q13.32-q13.33 and mosaic monosomy 22.

Molecular cytogenetics

Kashevarova AA, Belyaeva EO, Nikonov AM, Plotnikova OV, Skryabin NA, Nikitina TV, Vasilyev SA, Yakovleva YS, Babushkina NP, Tolmacheva EN, Lopatkina ME, Savchenko RR, Nazarenko LP, Lebedev IN.
PMID: 29736186
Mol Cytogenet. 2018 Apr 27;11:26. doi: 10.1186/s13039-018-0375-3. eCollection 2018.

BACKGROUND: Ring chromosome instability may influence a patient's phenotype and challenge its interpretation.RESULTS: Here, we report a 4-year-old girl with a compound phenotype. Cytogenetic analysis revealed her karyotype to be 46,XX,r(22). aCGH identified a 180 kb 22q13.32 duplication, a...

[Specialized foods with a modified carbohydrate profile in the correction of metabolic disorders in type 2 diabetes].

Voprosy pitaniia

Sharafetdinov KK, Plotnikova OA, Nazarova AM, Kondratieva OV.
PMID: 30592854
Vopr Pitan. 2017;86(6):56-66. doi: 10.24411/0042-8833-2017-00006. Epub 2017 Nov 07.

The review of the literature is devoted to the analysis of scientific publications concerning the optimization of nutrition of patients with diabetes mellitus (DM) type 2 due to inclusion in the ration of specialized foods with a modified carbohydrate...

Simulations of the Ultrafast Transient Absorption Dynamics of a Donor-Acceptor Biaryl in Solution.

The journal of physical chemistry. A

Fedunov RG, Plotnikova AV, Ivanov AI, Vauthey E.
PMID: 28010064
J Phys Chem A. 2017 Jan 19;121(2):471-481. doi: 10.1021/acs.jpca.6b11581. Epub 2017 Jan 06.

A model for simulating the transient electronic absorption spectra of donor-acceptor dyads undergoing ultrafast intramolecular charge transfer in solution has been developed. It is based on the stochastic multichannel point-transition approach and includes the reorganization of high-frequency intramolecular modes...

Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate.

Journal of medicinal chemistry

Machulkin AE, Uspenskaya AA, Zyk NU, Nimenko EA, Ber AP, Petrov SA, Polshakov VI, Shafikov RR, Skvortsov DA, Plotnikova EA, Pankratov AA, Smirnova GB, Borisova YA, Pokrovsky VS, Kolmogorov VS, Vaneev AN, Khudyakov AD, Chepikova OE, Kovalev S, Zamyatnin AA, Erofeev A, Gorelkin P, Beloglazkina EK, Zyk NV, Khazanova ES, Majouga AG.
PMID: 34797052
J Med Chem. 2021 Dec 09;64(23):17123-17145. doi: 10.1021/acs.jmedchem.1c01157. Epub 2021 Nov 19.

Prostate cancer is the second most common type of cancer among men. Its main method of treatment is chemotherapy, which has a wide range of side effects. One of the solutions to this challenge is targeted delivery to prostate...

[Nutrition management of the cancer patients: modern view on problem].

Voprosy pitaniia

Sharafetdinov KhKh, Plotnikova OA, Voznyĭ EK.
PMID: 18669325
Vopr Pitan. 2008;77(3):4-14.

In the review the current state of nutrition for patients with cancers is given. The role of nutrition in cancer etiology and prevention of cancers are discussed. Main principles of diet constriction in cancers are expounded.

Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate.

Journal of medicinal chemistry

Machulkin AE, Uspenskaya AA, Zyk NU, Nimenko EA, Ber AP, Petrov SA, Polshakov VI, Shafikov RR, Skvortsov DA, Plotnikova EA, Pankratov AA, Smirnova GB, Borisova YA, Pokrovsky VS, Kolmogorov VS, Vaneev AN, Khudyakov AD, Chepikova OE, Kovalev S, Zamyatnin AA, Erofeev A, Gorelkin P, Beloglazkina EK, Zyk NV, Khazanova ES, Majouga AG.
PMID: 34797052
J Med Chem. 2021 Dec 09;64(23):17123-17145. doi: 10.1021/acs.jmedchem.1c01157. Epub 2021 Nov 19.

Prostate cancer is the second most common type of cancer among men. Its main method of treatment is chemotherapy, which has a wide range of side effects. One of the solutions to this challenge is targeted delivery to prostate...

Adaptations of data mining methodologies: a systematic literature review.

PeerJ. Computer science

Plotnikova V, Dumas M, Milani F.
PMID: 33816918
PeerJ Comput Sci. 2020 May 25;6:e267. doi: 10.7717/peerj-cs.267. eCollection 2020.

The use of end-to-end data mining methodologies such as CRISP-DM, KDD process, and SEMMA has grown substantially over the past decade. However, little is known as to how these methodologies are used in practice. In particular, the question of...

Showing 1 to 12 of 28 entries