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Showing 1 to 12 of 38 entries
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Inverse Association of Plasma Level of Glutathione Peroxidase with Liver Fibrosis in Chronic Hepatitis B: Potential Role of Iron.

Middle East journal of digestive diseases

Moossavi S, Besharat S, Sharafkhah M, Ghanbari R, Sharifi A, Rezanejad P, Pourshams A, Poustchi H, Mohamadkhani A.
PMID: 27252819
Middle East J Dig Dis. 2016 Apr;8(2):122-30. doi: 10.15171/mejdd.2016.17.

BACKGROUND Oxidative stress has a major pathogenic role for liver damage following chronic hepatitis B. Glutathione peroxidase (Gpx) is necessary in oxidative state mechanism that is generally down-regulated by Hepatitis B virus (HBV) infection. On the other hand, disorders...

Kleine-Levin Syndrome in an 8-Year-Old Girl with Autistic Disorder: Does Autism Account a Primary or Secondary Cause?.

Iranian journal of child neurology

Hakim Shoushtari M, Ghalebandi M, Tavasoli A, Pourshams M.
PMID: 26664444
Iran J Child Neurol. 2015;9(4):61-4.

Objective Kleine-Levin syndrome (KLS) is a rare disorder with an unknown etiology. Autism spectrum disorder is characterized by various degrees of impairment in social communication, repetitive behavior and restricted interests. Only four patients of KLS with autistic spectrum disorder...

An Increased Level of Aryl Hydrocarbon Receptor in Patients with Pancreatic Cancer.

Middle East journal of digestive diseases

Masoudi S, Hassanzadeh Nemati A, Fazli HR, Beygi S, Moradzadeh M, Pourshams A, Mohamadkhani A.
PMID: 31049181
Middle East J Dig Dis. 2019 Jan;11(1):38-44. doi: 10.15171/mejdd.2018.126. Epub 2018 Oct 04.

BACKGROUND Aryl-carbon receptor (AhR), a ligand-activated transcription factor, is best known for its ability to mediate the effects of environmental toxins such as 2,3,7,8-tetrachlorodibenzo-p-dioxin. AhR is expressed in several tumor cells and regulates the expression of genes in the...

Diagnostic Significance of Serum Fatty Acid Synthase in Patients with Pancreatic Cancer.

Middle East journal of digestive diseases

Fazli HR, Moradzadeh M, Mehrbakhsh Z, Sharafkhah M, Masoudi S, Pourshams A, Mohamadkhani A.
PMID: 34712449
Middle East J Dig Dis. 2021 Apr;13(2):115-120. doi: 10.34172/mejdd.2021.214. Epub 2021 May 29.

BACKGROUND Pancreatic cancer is considered as the most deadly tumor among gastrointestinal cancers because of its poor prognosis. The frequently deregulated pathway in the cancer cell is associated with an increased expression of various genes, including the synthesis of...

Pancreatic Cancer is Associated with Peripheral Leukocyte Oxidative DNA Damage.

Asian Pacific journal of cancer prevention : APJCP

Mohamadkhani A, Pourshams A, Viti J, Cellai F, Mortazavi K, Sharafkhah M, Sotoudeh M, Malekzadeh R, Boffetta P, Peluso M.
PMID: 28612585
Asian Pac J Cancer Prev. 2017 May 01;18(5):1349-1355. doi: 10.22034/APJCP.2017.18.5.1349.

Background: DNA damage accumulation has been linked to the cancer phenotype. The purpose of this study was to compare the levels of DNA base 8-hydroxy-2′-deoxyguanosine (8-OHdG) and C-reactive protein (CRP) inflammatory markers in healthy controls and pancreatic cancer patients...

The survival rate of hepatocellular carcinoma in Asian countries: a systematic review and meta-analysis.

EXCLI journal

Hassanipour S, Vali M, Gaffari-Fam S, Nikbakht HA, Abdzadeh E, Joukar F, Pourshams A, Shafaghi A, Malakoutikhah M, Arab-Zozani M, Salehiniya H, Mansour-Ghanaei F.
PMID: 32038120
EXCLI J. 2020 Jan 13;19:108-130. doi: 10.17179/excli2019-1842. eCollection 2020.

Hepatocellular carcinoma or Liver cancer (LC) is the sixth most common cancer and the fourth cause of death worldwide in 2018. There has not been a comprehensive study on the survival rate of patients with LC in Asia yet....

Exposure to Polycyclic Aromatic Hydrocarbons Among Never Smokers in Golestan Province, Iran, an Area of High Incidence of Esophageal Cancer - a Cross-Sectional Study with Repeated Measurement of Urinary 1-OHPG in Two Seasons.

Frontiers in oncology

Islami F, Boffetta P, van Schooten FJ, Strickland P, Phillips DH, Pourshams A, Fazel-Tabar Malekshah A, Godschalk R, Jafari E, Etemadi A, Abubaker S, Kamangar F, Straif K, Møller H, Schüz J, Malekzadeh R.
PMID: 22655262
Front Oncol. 2012 Feb 17;2:14. doi: 10.3389/fonc.2012.00014. eCollection 2012.

Studies have suggested a possible role of polycyclic aromatic hydrocarbons (PAHs) in the etiology of esophageal cancer in Golestan Province, Iran, where incidence of this cancer is very high. In order to investigate the patterns of non-smoking related exposure...

Normal limit for serum alanine aminotransferase level and distribution of metabolic factors in old population of kalaleh, iran.

Hepatitis monthly

Kabir A, Pourshams A, Khoshnia M, Malekzadeh F.
PMID: 24348633
Hepat Mon. 2013 Oct 20;13(10):e10640. doi: 10.5812/hepatmon.10640. eCollection 2013.

BACKGROUNDS: Normal or elevated values of serum alanine aminotransferase level (ALT) vary in different studies mostly related to characteristics of reference population including age, gender, body mass index, nonalcoholic fatty liver disease (NAFLD), and metabolic syndrome prevalence.OBJECTIVES: To measure...

Gastroesophageal Reflux Disease and overall and Cause-specific Mortality: A Prospective Study of 50000 Individuals.

Middle East journal of digestive diseases

Islami F, Pourshams A, Nasseri-Moghaddam S, Khademi H, Poutschi H, Khoshnia M, Norouzi A, Amiriani T, Sohrabpour AA, Aliasgari A, Jafari E, Semnani S, Abnet CC, Pharaoh PD, Brennan P, Kamangar F, Dawsey SM, Boffetta P, Malekzadeh R.
PMID: 24872865
Middle East J Dig Dis. 2014 Apr;6(2):65-80.

BACKGROUND Only a few studies in Western countries have investigated the association between gastroesophageal reflux disease (GERD) and mortality at the general population level and they have shown mixed results. This study investigated the association between GERD symptoms and...

Oral Health and Risk of Upper Gastrointestinal Cancers in a Large Prospective Study from a High-risk Region: Golestan Cohort Study.

Cancer prevention research (Philadelphia, Pa.)

Yano Y, Abnet CC, Poustchi H, Roshandel G, Pourshams A, Islami F, Khoshnia M, Amiriani T, Norouzi A, Kamangar F, Boffetta P, Brennan P, Dawsey SM, Vogtmann E, Malekzadeh R, Etemadi A.
PMID: 33731409
Cancer Prev Res (Phila). 2021 Jul;14(7):709-718. doi: 10.1158/1940-6207.CAPR-20-0577. Epub 2021 Mar 17.

Tooth loss and periodontal disease have been associated with several cancers, and poor oral health may be an important risk factor for upper gastrointestinal (UGI, i.e., esophageal and gastric) cancers. We assessed the relationship between oral health and UGI...

Corrigendum to: Joint effect of diabetes and opiate use on all-cause and cause-specific mortality: the Golestan cohort study.

International journal of epidemiology

Nalini M, Khoshnia M, Kamangar F, Sharafkhah M, Poustchi H, Pourshams A, Roshandel G, Gharavi S, Zahedi M, Norouzi A, Sotoudeh M, Nikmanesh A, Brennan P, Boffetta P, Dawsey SM, Abnet CC, Malekzadeh R, Etemadi A.
PMID: 33367601
Int J Epidemiol. 2021 Mar 03;50(1):353. doi: 10.1093/ije/dyaa268.

No abstract available.

Oral Health and Risk of Upper Gastrointestinal Cancers in a Large Prospective Study from a High-risk Region: Golestan Cohort Study.

Cancer prevention research (Philadelphia, Pa.)

Yano Y, Abnet CC, Poustchi H, Roshandel G, Pourshams A, Islami F, Khoshnia M, Amiriani T, Norouzi A, Kamangar F, Boffetta P, Brennan P, Dawsey SM, Vogtmann E, Malekzadeh R, Etemadi A.
PMID: 33731409
Cancer Prev Res (Phila). 2021 Jul;14(7):709-718. doi: 10.1158/1940-6207.CAPR-20-0577. Epub 2021 Mar 17.

Tooth loss and periodontal disease have been associated with several cancers, and poor oral health may be an important risk factor for upper gastrointestinal (UGI, i.e., esophageal and gastric) cancers. We assessed the relationship between oral health and UGI...

Showing 1 to 12 of 38 entries