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Age related retinal Ganglion cell susceptibility in context of autophagy deficiency.

Cell death discovery

Bell K, Rosignol I, Sierra-Filardi E, Rodriguez-Muela N, Schmelter C, Cecconi F, Grus F, Boya P.
PMID: 32337073
Cell Death Discov. 2020 Apr 17;6:21. doi: 10.1038/s41420-020-0257-4. eCollection 2020.

Glaucoma is a common age-related disease leading to progressive retinal ganglion cell (RGC) death, visual field defects and vision loss and is the second leading cause of blindness in the elderly worldwide. Mitochondrial dysfunction and impaired autophagy have been...

Standard Assays for the Study of Autophagy in the Ex Vivo Retina.

Cells

Gómez-Sintes R, Villarejo-Zori B, Serrano-Puebla A, Esteban-Martínez L, Sierra-Filardi E, Ramírez-Pardo I, Rodríguez-Muela N, Boya P.
PMID: 29065501
Cells. 2017 Oct 22;6(4). doi: 10.3390/cells6040037.

Autophagy is a catabolic pathway that mediates the degradation and recycling of intracellular components, and is a key player in a variety of physiological processes in cells and tissues. Recent studies of autophagy in the eye suggest that this...

Showing 1 to 2 of 2 entries