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Sarcopenia Is Associated with High Pulse Pressure in Older Women.

Journal of aging research

Coelho Júnior HJ, Aguiar Sda S, Gonçalves Ide O, Sampaio RA, Uchida MC, Moraes MR, Asano RY.
PMID: 26346157
J Aging Res. 2015;2015:109824. doi: 10.1155/2015/109824. Epub 2015 Aug 05.

Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been...

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Coelho Júnior HJ, Aguiar Sda S, Gonçalves Ide O, et al. Sarcopenia Is Associated with High Pulse Pressure in Older Women. J Aging Res. 2015;2015:109824doi: 10.1155/2015/109824.
Coelho Júnior, H. J., Aguiar, S. d. a. . S., Gonçalves, I. d. e. . O., Sampaio, R. A., Uchida, M. C., Moraes, M. R., & Asano, R. Y. (2015). Sarcopenia Is Associated with High Pulse Pressure in Older Women. Journal of aging research, 2015109824. https://doi.org/10.1155/2015/109824
Coelho Júnior, Hélio José, et al. "Sarcopenia Is Associated with High Pulse Pressure in Older Women." Journal of aging research vol. 2015 (2015): 109824. doi: https://doi.org/10.1155/2015/109824
Coelho Júnior HJ, Aguiar Sda S, Gonçalves Ide O, Sampaio RA, Uchida MC, Moraes MR, Asano RY. Sarcopenia Is Associated with High Pulse Pressure in Older Women. J Aging Res. 2015;2015:109824. doi: 10.1155/2015/109824. Epub 2015 Aug 05. PMID: 26346157; PMCID: PMC4541009.
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Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells.

Hepatology research : the official journal of the Japan Society of Hepatology

Goto F, Kakinuma S, Miyoshi M, Tsunoda T, Kaneko S, Sato A, Asano Y, Otani S, Azuma S, Nagata H, Kawai-Kitahata F, Murakawa M, Nitta S, Itsui Y, Nakagawa M, Asahina Y, Watanabe M.
PMID: 27670640
Hepatol Res. 2017 Aug;47(9):941-952. doi: 10.1111/hepr.12823. Epub 2016 Oct 31.

Fetal hepatic stem/progenitor cells, called hepatoblasts, play central roles in liver organogenesis; however, molecular mechanisms regulating proliferation and terminal differentiation of such cells have not been completely elucidated. Bone morphogenetic protein-4 (BMP-4) is essential for the development of stem...

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Goto F, Kakinuma S, Miyoshi M, et al. Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells. Hepatol Res. 2016;47(9):941-952doi: 10.1111/hepr.12823.
Goto, F., Kakinuma, S., Miyoshi, M., Tsunoda, T., Kaneko, S., Sato, A., Asano, Y., Otani, S., Azuma, S., Nagata, H., Kawai-Kitahata, F., Murakawa, M., Nitta, S., Itsui, Y., Nakagawa, M., Asahina, Y., & Watanabe, M. (2017). Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells. Hepatology research : the official journal of the Japan Society of Hepatology, 47(9), 941-952. https://doi.org/10.1111/hepr.12823
Goto, Fumio, et al. "Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells." Hepatology research : the official journal of the Japan Society of Hepatology vol. 47,9 (2017): 941-952. doi: https://doi.org/10.1111/hepr.12823
Goto F, Kakinuma S, Miyoshi M, Tsunoda T, Kaneko S, Sato A, Asano Y, Otani S, Azuma S, Nagata H, Kawai-Kitahata F, Murakawa M, Nitta S, Itsui Y, Nakagawa M, Asahina Y, Watanabe M. Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells. Hepatol Res. 2017 Aug;47(9):941-952. doi: 10.1111/hepr.12823. Epub 2016 Oct 31. PMID: 27670640.
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Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers.

Clinical pharmacology : advances and applications

Kawabata M, Yokoyama Y, Sasaki T, Tao S, Ihara K, Shirai Y, Sasano T, Goya M, Furukawa T, Isobe M, Hirao K.
PMID: 25733934
Clin Pharmacol. 2015 Feb 16;7:29-36. doi: 10.2147/CPAA.S77021. eCollection 2015.

PURPOSE: Drug-induced bradycardia is common during antiarrhythmic therapy; the major culprits are beta-blockers. However, whether other antiarrhythmic drugs are also a significant cause of this, alone or in combination with beta-blockers, is not well known.METHODS: We retrospectively investigated the...

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Kawabata M, Yokoyama Y, Sasaki T, et al. Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers. Clin Pharmacol. 2015;7:29-36doi: 10.2147/CPAA.S77021.
Kawabata, M., Yokoyama, Y., Sasaki, T., Tao, S., Ihara, K., Shirai, Y., Sasano, T., Goya, M., Furukawa, T., Isobe, M., & Hirao, K. (2015). Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers. Clinical pharmacology : advances and applications, 729-36. https://doi.org/10.2147/CPAA.S77021
Kawabata, Mihoko, et al. "Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers." Clinical pharmacology : advances and applications vol. 7 (2015): 29-36. doi: https://doi.org/10.2147/CPAA.S77021
Kawabata M, Yokoyama Y, Sasaki T, Tao S, Ihara K, Shirai Y, Sasano T, Goya M, Furukawa T, Isobe M, Hirao K. Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers. Clin Pharmacol. 2015 Feb 16;7:29-36. doi: 10.2147/CPAA.S77021. eCollection 2015. PMID: 25733934; PMCID: PMC4337503.
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Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report.

Oncology letters

Fasano M, Fabozzi A, Giordano G, Venturini F, Aurilio G, Cantile F, Fabozzi T, Ricci V, Santabarbara G, Morgillo F, Ciardiello F, De Vita F.
PMID: 28356988
Oncol Lett. 2017 Feb;13(2):979-983. doi: 10.3892/ol.2016.5523. Epub 2016 Dec 20.

The clinical management of frail, elderly patients affected by colorectal cancer (CRC) remains a subject of debate. The present study reports the case of an elderly man with metastatic CRC (mCRC) who was successfully treated with capecitabine. The patient...

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Fasano M, Fabozzi A, Giordano G, et al. Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report. Oncol Lett. 2016;13(2):979-983doi: 10.3892/ol.2016.5523.
Fasano, M., Fabozzi, A., Giordano, G., Venturini, F., Aurilio, G., Cantile, F., Fabozzi, T., Ricci, V., Santabarbara, G., Morgillo, F., Ciardiello, F., & De Vita, F. (2017). Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report. Oncology letters, 13(2), 979-983. https://doi.org/10.3892/ol.2016.5523
Fasano, Morena, et al. "Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report." Oncology letters vol. 13,2 (2017): 979-983. doi: https://doi.org/10.3892/ol.2016.5523
Fasano M, Fabozzi A, Giordano G, Venturini F, Aurilio G, Cantile F, Fabozzi T, Ricci V, Santabarbara G, Morgillo F, Ciardiello F, De Vita F. Complete response to capecitabine in a frail, elderly patient with metastatic colorectal cancer: A case report. Oncol Lett. 2017 Feb;13(2):979-983. doi: 10.3892/ol.2016.5523. Epub 2016 Dec 20. PMID: 28356988; PMCID: PMC5351201.
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Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus.

International journal of surgery case reports

Ishida H, Nakano T, Fujishima F, Kamei T, Taniyama Y, Sakurai T, Sato C, Fukutomi T, Kamiya K, Ozawa Y, Sasano H, Ohuchi N.
PMID: 26629851
Int J Surg Case Rep. 2015;17:151-4. doi: 10.1016/j.ijscr.2015.11.013. Epub 2015 Nov 26.

INTRODUCTION: Basaloid squamous cell carcinoma of the oesophagus (BSCCE) is a relatively rare variant of oesophageal malignancy. There are no established treatment strategies for pulmonary metastases of BSCCE.PRESENTATION OF CASE: A 72-year-old man underwent oesophagectomy and subsequently received a...

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Ishida H, Nakano T, Fujishima F, et al. Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus. Int J Surg Case Rep. 2015;17:151-4doi: 10.1016/j.ijscr.2015.11.013.
Ishida, H., Nakano, T., Fujishima, F., Kamei, T., Taniyama, Y., Sakurai, T., Sato, C., Fukutomi, T., Kamiya, K., Ozawa, Y., Sasano, H., & Ohuchi, N. (2015). Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus. International journal of surgery case reports, 17151-4. https://doi.org/10.1016/j.ijscr.2015.11.013
Ishida, Hirotaka, et al. "Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus." International journal of surgery case reports vol. 17 (2015): 151-4. doi: https://doi.org/10.1016/j.ijscr.2015.11.013
Ishida H, Nakano T, Fujishima F, Kamei T, Taniyama Y, Sakurai T, Sato C, Fukutomi T, Kamiya K, Ozawa Y, Sasano H, Ohuchi N. Surgical resection and chemoradiotherapy for metachronous pulmonary metastasis of basaloid squamous cell carcinoma of the oesophagus. Int J Surg Case Rep. 2015;17:151-4. doi: 10.1016/j.ijscr.2015.11.013. Epub 2015 Nov 26. PMID: 26629851; PMCID: PMC4701867.
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Distribution of vesicular glutamate transporters in the human brain.

Frontiers in neuroanatomy

Vigneault É, Poirel O, Riad M, Prud'homme J, Dumas S, Turecki G, Fasano C, Mechawar N, El Mestikawy S.
PMID: 25798091
Front Neuroanat. 2015 Mar 05;9:23. doi: 10.3389/fnana.2015.00023. eCollection 2015.

Glutamate is the major excitatory transmitter in the brain. Vesicular glutamate transporters (VGLUT1-3) are responsible for uploading glutamate into synaptic vesicles. VGLUT1 and VGLUT2 are considered as specific markers of canonical glutamatergic neurons, while VGLUT3 is found in neurons...

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Vigneault É, Poirel O, Riad M, et al. Distribution of vesicular glutamate transporters in the human brain. Front Neuroanat. 2015;9:23doi: 10.3389/fnana.2015.00023.
Vigneault, �. �., Poirel, O., Riad, M., Prud'homme, J., Dumas, S., Turecki, G., Fasano, C., Mechawar, N., & El Mestikawy, S. (2015). Distribution of vesicular glutamate transporters in the human brain. Frontiers in neuroanatomy, 923. https://doi.org/10.3389/fnana.2015.00023
Vigneault, Érika, et al. "Distribution of vesicular glutamate transporters in the human brain." Frontiers in neuroanatomy vol. 9 (2015): 23. doi: https://doi.org/10.3389/fnana.2015.00023
Vigneault É, Poirel O, Riad M, Prud'homme J, Dumas S, Turecki G, Fasano C, Mechawar N, El Mestikawy S. Distribution of vesicular glutamate transporters in the human brain. Front Neuroanat. 2015 Mar 05;9:23. doi: 10.3389/fnana.2015.00023. eCollection 2015. PMID: 25798091; PMCID: PMC4350397.
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Nonequilibrium molecular dynamics simulations of nanoconfined fluids at solid-liquid interfaces.

The Journal of chemical physics

Morciano M, Fasano M, Nold A, Braga C, Yatsyshin P, Sibley DN, Goddard BD, Chiavazzo E, Asinari P, Kalliadasis S.
PMID: 28668055
J Chem Phys. 2017 Jun 28;146(24):244507. doi: 10.1063/1.4986904.

We investigate the hydrodynamic properties of a Lennard-Jones fluid confined to a nanochannel using molecular dynamics simulations. For channels of different widths and hydrophilic-hydrophobic surface wetting properties, profiles of the fluid density, stress, and viscosity across the channel are...

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Morciano M, Fasano M, Nold A, et al. Nonequilibrium molecular dynamics simulations of nanoconfined fluids at solid-liquid interfaces. J Chem Phys. 2017;146(24):244507doi: 10.1063/1.4986904.
Morciano, M., Fasano, M., Nold, A., Braga, C., Yatsyshin, P., Sibley, D. N., Goddard, B. D., Chiavazzo, E., Asinari, P., & Kalliadasis, S. (2017). Nonequilibrium molecular dynamics simulations of nanoconfined fluids at solid-liquid interfaces. The Journal of chemical physics, 146(24), 244507. https://doi.org/10.1063/1.4986904
Morciano, M, et al. "Nonequilibrium molecular dynamics simulations of nanoconfined fluids at solid-liquid interfaces." The Journal of chemical physics vol. 146,24 (2017): 244507. doi: https://doi.org/10.1063/1.4986904
Morciano M, Fasano M, Nold A, Braga C, Yatsyshin P, Sibley DN, Goddard BD, Chiavazzo E, Asinari P, Kalliadasis S. Nonequilibrium molecular dynamics simulations of nanoconfined fluids at solid-liquid interfaces. J Chem Phys. 2017 Jun 28;146(24):244507. doi: 10.1063/1.4986904. PMID: 28668055.
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REGULATION OF BIOSYNTHESIS OF DIMETHYLSULFONIOPROPIONATE AND ITS UPTAKE IN STERILE MUTANT OF ULVA PERTUSA (CHLOROPHYTA).

Journal of phycology

Ito T, Asano Y, Tanaka Y, Takabe T.
PMID: 27021980
J Phycol. 2011 Jun;47(3):517-523. doi: 10.1111/j.1529-8817.2011.00977.x. Epub 2011 Apr 11.

It has been shown that marine algae produce the compatible solute dimethylsulfoniopropionate (DMSP) from methionine (Met) via four enzymatic reactions in which the third step, synthesis of 4-dimethylsulfonio-2-hydroxy-butyrate (DMSHB) from 4-methylthio-2-hydroxybutyrate (MTHB), is the committing step. However, regulation of...

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Ito T, Asano Y, Tanaka Y, et al. REGULATION OF BIOSYNTHESIS OF DIMETHYLSULFONIOPROPIONATE AND ITS UPTAKE IN STERILE MUTANT OF ULVA PERTUSA (CHLOROPHYTA). J Phycol. 2011;47(3):517-523doi: 10.1111/j.1529-8817.2011.00977.x.
Ito, T., Asano, Y., Tanaka, Y., & Takabe, T. (2011). REGULATION OF BIOSYNTHESIS OF DIMETHYLSULFONIOPROPIONATE AND ITS UPTAKE IN STERILE MUTANT OF ULVA PERTUSA (CHLOROPHYTA). Journal of phycology, 47(3), 517-523. https://doi.org/10.1111/j.1529-8817.2011.00977.x
Ito, Takayuki, et al. "REGULATION OF BIOSYNTHESIS OF DIMETHYLSULFONIOPROPIONATE AND ITS UPTAKE IN STERILE MUTANT OF ULVA PERTUSA (CHLOROPHYTA)." Journal of phycology vol. 47,3 (2011): 517-523. doi: https://doi.org/10.1111/j.1529-8817.2011.00977.x
Ito T, Asano Y, Tanaka Y, Takabe T. REGULATION OF BIOSYNTHESIS OF DIMETHYLSULFONIOPROPIONATE AND ITS UPTAKE IN STERILE MUTANT OF ULVA PERTUSA (CHLOROPHYTA). J Phycol. 2011 Jun;47(3):517-523. doi: 10.1111/j.1529-8817.2011.00977.x. Epub 2011 Apr 11. PMID: 27021980.
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Thermal transport across nanoparticle-fluid interfaces: the interplay of interfacial curvature and nanoparticle-fluid interactions.

Physical chemistry chemical physics : PCCP

Tascini AS, Armstrong J, Chiavazzo E, Fasano M, Asinari P, Bresme F.
PMID: 28083587
Phys Chem Chem Phys. 2017 Jan 25;19(4):3244-3253. doi: 10.1039/c6cp06403e.

We investigate the general dependence of the thermal transport across nanoparticle-fluid interfaces using molecular dynamics computations. We show that the thermal conductance depends strongly both on the wetting characteristics of the nanoparticle-fluid interface and on the nanoparticle size. Strong...

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Tascini AS, Armstrong J, Chiavazzo E, et al. Thermal transport across nanoparticle-fluid interfaces: the interplay of interfacial curvature and nanoparticle-fluid interactions. Phys Chem Chem Phys. 2017;19(4):3244-3253doi: 10.1039/c6cp06403e.
Tascini, A. S., Armstrong, J., Chiavazzo, E., Fasano, M., Asinari, P., & Bresme, F. (2017). Thermal transport across nanoparticle-fluid interfaces: the interplay of interfacial curvature and nanoparticle-fluid interactions. Physical chemistry chemical physics : PCCP, 19(4), 3244-3253. https://doi.org/10.1039/c6cp06403e
Tascini, Anna Sofia, et al. "Thermal transport across nanoparticle-fluid interfaces: the interplay of interfacial curvature and nanoparticle-fluid interactions." Physical chemistry chemical physics : PCCP vol. 19,4 (2017): 3244-3253. doi: https://doi.org/10.1039/c6cp06403e
Tascini AS, Armstrong J, Chiavazzo E, Fasano M, Asinari P, Bresme F. Thermal transport across nanoparticle-fluid interfaces: the interplay of interfacial curvature and nanoparticle-fluid interactions. Phys Chem Chem Phys. 2017 Jan 25;19(4):3244-3253. doi: 10.1039/c6cp06403e. PMID: 28083587.
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Chronic hepatitis B: Advances in treatment.

World journal of hepatology

Santantonio TA, Fasano M.
PMID: 24868322
World J Hepatol. 2014 May 27;6(5):284-92. doi: 10.4254/wjh.v6.i5.284.

Treatment of chronic hepatitis B (CHB) has markedly improved in the last 15 years due to the availability of direct antivirals which greatly increase therapeutic options. Currently, there are two classes of agents licensed for CHB treatment: standard or...

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Santantonio TA, Fasano M. Chronic hepatitis B: Advances in treatment. World J Hepatol. 2014;6(5):284-92doi: 10.4254/wjh.v6.i5.284.
Santantonio, T. A., & Fasano, M. (2014). Chronic hepatitis B: Advances in treatment. World journal of hepatology, 6(5), 284-92. https://doi.org/10.4254/wjh.v6.i5.284
Santantonio, Teresa Antonia, and Fasano, Massimo. "Chronic hepatitis B: Advances in treatment." World journal of hepatology vol. 6,5 (2014): 284-92. doi: https://doi.org/10.4254/wjh.v6.i5.284
Santantonio TA, Fasano M. Chronic hepatitis B: Advances in treatment. World J Hepatol. 2014 May 27;6(5):284-92. doi: 10.4254/wjh.v6.i5.284. PMID: 24868322; PMCID: PMC4033286.
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Mutagenesis of an Asn156 Residue in a Surface Region of S-Selective Hydroxynitrile Lyase from Baliospermum montanum Enhances Catalytic Efficiency and Enantioselectivity.

Chembiochem : a European journal of chemical biology

Kawahara N, Asano Y.
PMID: 26109164
Chembiochem. 2015 Sep 07;16(13):1891-1895. doi: 10.1002/cbic.201500225. Epub 2015 Jul 27.

The S-selective hydroxynitrile lyase from Baliospermum montanum (BmHNL) has broad substrate specificity toward aromatic substrates as well as high temperature stability, although with low enantioselectivity and specific activity. To expand the industrial application of this enzyme, we improved its...

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Kawahara N, Asano Y. Mutagenesis of an Asn156 Residue in a Surface Region of S-Selective Hydroxynitrile Lyase from Baliospermum montanum Enhances Catalytic Efficiency and Enantioselectivity. Chembiochem. 2015;16(13):1891-1895doi: 10.1002/cbic.201500225.
Kawahara, N., & Asano, Y. (2015). Mutagenesis of an Asn156 Residue in a Surface Region of S-Selective Hydroxynitrile Lyase from Baliospermum montanum Enhances Catalytic Efficiency and Enantioselectivity. Chembiochem : a European journal of chemical biology, 16(13), 1891-1895. https://doi.org/10.1002/cbic.201500225
Kawahara, Nobuhiro, and Asano, Yasuhisa. "Mutagenesis of an Asn156 Residue in a Surface Region of S-Selective Hydroxynitrile Lyase from Baliospermum montanum Enhances Catalytic Efficiency and Enantioselectivity." Chembiochem : a European journal of chemical biology vol. 16,13 (2015): 1891-1895. doi: https://doi.org/10.1002/cbic.201500225
Kawahara N, Asano Y. Mutagenesis of an Asn156 Residue in a Surface Region of S-Selective Hydroxynitrile Lyase from Baliospermum montanum Enhances Catalytic Efficiency and Enantioselectivity. Chembiochem. 2015 Sep 07;16(13):1891-1895. doi: 10.1002/cbic.201500225. Epub 2015 Jul 27. PMID: 26109164.
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Size-Induced Depression of First-Order Transition Lines and Entropy Jump in Extremely Layered Nanocrystalline Vortex Matter.

Physical review letters

Dolz MI, Fasano Y, Cejas Bolecek NR, Pastoriza H, Mosser V, Li M, Konczykowski M.
PMID: 26451579
Phys Rev Lett. 2015 Sep 25;115(13):137003. doi: 10.1103/PhysRevLett.115.137003. Epub 2015 Sep 25.

We detect the persistence of the solidification and order-disorder first-order transition lines in the phase diagram of nanocrystalline Bi_{2}Sr_{2}CaCu_{2}O_{8} vortex matter down to a system size of less than one hundred vortices. The temperature location of the vortex solidification...

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Dolz MI, Fasano Y, Cejas Bolecek NR, et al. Size-Induced Depression of First-Order Transition Lines and Entropy Jump in Extremely Layered Nanocrystalline Vortex Matter. Phys Rev Lett. 2015;115(13):137003doi: 10.1103/PhysRevLett.115.137003.
Dolz, M. I., Fasano, Y., Cejas Bolecek, N. R., Pastoriza, H., Mosser, V., Li, M., & Konczykowski, M. (2015). Size-Induced Depression of First-Order Transition Lines and Entropy Jump in Extremely Layered Nanocrystalline Vortex Matter. Physical review letters, 115(13), 137003. https://doi.org/10.1103/PhysRevLett.115.137003
Dolz, M I, et al. "Size-Induced Depression of First-Order Transition Lines and Entropy Jump in Extremely Layered Nanocrystalline Vortex Matter." Physical review letters vol. 115,13 (2015): 137003. doi: https://doi.org/10.1103/PhysRevLett.115.137003
Dolz MI, Fasano Y, Cejas Bolecek NR, Pastoriza H, Mosser V, Li M, Konczykowski M. Size-Induced Depression of First-Order Transition Lines and Entropy Jump in Extremely Layered Nanocrystalline Vortex Matter. Phys Rev Lett. 2015 Sep 25;115(13):137003. doi: 10.1103/PhysRevLett.115.137003. Epub 2015 Sep 25. PMID: 26451579.
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