Scientific reports

Smiley S, Nickerson PE, Comanita L, Daftarian N, El-Sehemy A, Tsai EL, Matan-Lithwick S, Yan K, Thurig S, Touahri Y, Dixit R, Aavani T, De Repentingy Y, Baker A, Tsilfidis C, Biernaskie J, Sauvé Y, Schuurmans C, Kothary R, Mears AJ, Wallace VA.
PMID: 26965927
Sci Rep. 2016 Mar 11;6:22867. doi: 10.1038/srep22867.

We report successful retinal cone enrichment and transplantation using a novel cone-GFP reporter mouse line. Using the putative cone photoreceptor-enriched transcript Coiled-Coil Domain Containing 136 (Ccdc136) GFP-trapped allele, we monitored developmental reporter expression, facilitated the enrichment of cones, and...

International journal of bipolar disorders

Pfennig A, Alda M, Young T, MacQueen G, Rybakowski J, Suwalska A, Simhandl C, König B, Hajek T, O'Donovan C, Wittekind D, von Quillfeldt S, Ploch J, Sauer C, Bauer M.
PMID: 25540718
Int J Bipolar Disord. 2014 Dec 24;2:1. doi: 10.1186/s40345-014-0016-7. eCollection 2014.

Cognitive impairment in patients with bipolar disorder (BD) is not restricted to symptomatic phases. It is also present in euthymia. There is evidence of differences in the brain's structure between bipolar patients and healthy individuals, as well as changes...

The journal of physical chemistry letters

Senevirathna W, Daddario CM, Sauvé G.
PMID: 26274092
J Phys Chem Lett. 2014 Mar 06;5(5):935-41. doi: 10.1021/jz402735c. Epub 2014 Feb 25.

Small internal reorganization energy is desirable for high-performance optoelectronic materials, as it facilitates both charge separation and charge transport. However, only a handful of n-type electron accepting materials are known to have small reorganization energies. Here, DFT calculations were...

Optics express

Walder R, Paik DH, Bull MS, Sauer C, Perkins TT.
PMID: 26191667
Opt Express. 2015 Jun 29;23(13):16554-64. doi: 10.1364/OE.23.016554.

Advanced optical traps can probe single molecules with Ångstrom-scale precision, but drift limits the utility of these instruments. To achieve Å-scale stability, a differential measurement scheme between a pair of laser foci was introduced that substantially exceeds the inherent...

Stem cells international

Baugé C, Boumédiene K.
PMID: 26246809
Stem Cells Int. 2015;2015:438026. doi: 10.1155/2015/438026. Epub 2015 Jul 09.

Due to their low self-repair ability, cartilage defects that result from joint injury, aging, or osteoarthritis, are the most often irreversible and are a major cause of joint pain and chronic disability. So, in recent years, researchers and surgeons...

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Larson CP, Sauvé L, Senkungu JK, Arifeen SE, Brant R.
PMID: 25859167
J Pediatr Pharmacol Ther. 2015 Jan-Feb;20(1):24-32. doi: 10.5863/1551-6776-20.1.24.

OBJECTIVES: Conversion of pediatric essential drugs from syrup to dispersible tablet formulations would require fixed dose options guided by the weight band in which a child falls or a proxy for weight, such as height or age. The purpose...

Frontiers in psychiatry

Morand-Beaulieu S, O'Connor KP, Richard M, Sauvé G, Leclerc JB, Blanchet PJ, Lavoie ME.
PMID: 27242551
Front Psychiatry. 2016 May 10;7:81. doi: 10.3389/fpsyt.2016.00081. eCollection 2016.

CONTEXT: Tic disorders (TD) are characterized by the presence of non-voluntary contractions of functionally related groups of skeletal muscles in one or multiple body parts. Patients with body-focused repetitive behaviors (BFRB) present frequent and repetitive behaviors, such as nail...

Echo research and practice

Lebeau R, Sas G, El Rayes M, Serban A, Moustafa S, Essadiqi B, DiLorenzo M, Souliere V, Beaulieu Y, Sauve C, Amyot R, Serri K.
PMID: 26693310
Echo Res Pract. 2015 Mar 01;2(1):1-8. doi: 10.1530/ERP-14-0003. Epub 2015 Jan 06.

For the non-cardiologist emergency physician and intensivist, performing an accurate estimation of left ventricular ejection fraction (LVEF) is essential for the management of critically ill patients, such as patients presenting with shock, severe respiratory distress or chest pain. Our...

Organic letters

Bouzide A, Sauvé G.
PMID: 12098239
Org Lett. 2002 Jul 11;4(14):2329-32. doi: 10.1021/ol020071y.

[reaction: see text] The reaction of symmetrical diols and oligo(ethylene glycol)s with a stoichiometric amount of p-toluenesulfonyl chloride in the presence of silver(I) oxide and a catalytic amount of potassium iodide led selectively to the monotosylate derivatives in high...

Chemistry Central journal

Stephan CH, Fournier M, Brousseau P, Sauvé S.
PMID: 18479524
Chem Cent J. 2008 May 14;2:10. doi: 10.1186/1752-153X-2-10.

BACKGROUND: Occupational exposure to beryllium may cause Chronic Beryllium Disease (CBD), a lung disorder initiated by an electrostatic interaction with the MHC class II human leukocyte antigen (HLA). Molecular studies have found a significant correlation between the electrostatic potential...

Nature

Aharonian FA, Akhperjanian AG, Aye KM, Bazer-Bachi AR, Beilicke M, Benbow W, Berge D, Berghaus P, Bernlöhr K, Bolz O, Boisson C, Borgmeier C, Breitling F, Brown AM, Gordo JB, Chadwick PM, Chitnis VR, Chounet LM, Cornils R, Costamante L, Degrange B, Djannati-Ataï A, Drury LO, Ergin T, Espigat P, Feinstein F, Fleury P, Fontaine G, Funk S, Gallant YA, Giebels B, Gillessen S, Goret P, Guy J, Hadjichristidis C, Hauser M, Heinzelmann G, Henri G, Hermann G, Hinton JA, Hofmann W, Holleran M, Horns D, De Jager OC, Jung I, Khélifi B, Komin N, Konopelko A, Latham IJ, Le Gallou R, Lemoine M, Lemière A, Leroy N, Lohse T, Marcowith A, Masterson C, McComb TJ, De Naurois M, Nolan SJ, Noutsos A, Orford KJ, Osborne JL, Ouchrif M, Panter M, Pelletier G, Pita S, Pohl M, Pühlhofer G, Punch M, Raubenheimer BC, Raue M, Raux J, Rayner SM, Redondo I, Reimer A, Reimer O, Ripken J, Rivoal M, Rob L, Rolland L, Rowell G, Sahakian V, Saugé L, Schlenker S, Schlickeiser R, Schuster C, Schwanke U, Siewert M, Sol H, Steenkamp R, Stegmann C, Tavernet JP, Théoret CG, Tluczykont M, Van Der Walt DJ, Vasileiadis G, Vincent P, Visser B, Völk HJ, Wagner SJ.
PMID: 15525982
Nature. 2004 Nov 04;432(7013):75-7. doi: 10.1038/nature02960.

A significant fraction of the energy density of the interstellar medium is in the form of high-energy charged particles (cosmic rays). The origin of these particles remains uncertain. Although it is generally accepted that the only sources capable of...

Analytical chemistry

Fayad PB, Prévost M, Sauvé S.
PMID: 20000768
Anal Chem. 2010 Jan 15;82(2):639-45. doi: 10.1021/ac902074x.

A rapid and reliable method enabling high-throughput sample analysis for quicker data generation, detection, and monitoring of eight selected steroid hormones in water matrixes was developed and validated. Our approach is based on a novel sample introduction method, the...