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Influence of acute normobaric hypoxia on physiological variables and lactate turn point determination in trained men.

Journal of sports science & medicine

Ofner M, Wonisch M, Frei M, Tschakert G, Domej W, Kröpfl JM, Hofmann P.
PMID: 25435769
J Sports Sci Med. 2014 Dec 01;13(4):774-81. eCollection 2014 Dec.

The goal of this study is to evaluate the response of physiological variables to acute normobaric hypoxia compared to normoxia and its influence on the lactate turn point determination according to the three-phase model of energy supply (Phase I:...

Qualitative and quantitative assessment of the benefit-risk ratio of medium potency topical corticosteroids in vitro and in vivo: characterisation of drugs with an increased benefit-risk ratio.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Schackert C, Korting HC, Schäfer-Korting M.
PMID: 18034533
BioDrugs. 2000 Apr;13(4):267-77. doi: 10.2165/00063030-200013040-00005.

Corticosteroids are widely used for the treatment of inflammatory skin disorders. However, systemic and local adverse drug reactions, especially skin atrophy, are potential complications that limit their use. Several attempts have been made to increase the safety of topical...

The Problem of Metal Needles in Acupuncture-fMRI Studies.

Evidence-based complementary and alternative medicine : eCAM

Beissner F, Nöth U, Schockert T.
PMID: 21423640
Evid Based Complement Alternat Med. 2011;2011:808203. doi: 10.1155/2011/808203. Epub 2011 Mar 01.

Acupuncture is a therapy based on sensory stimulation of the human body by means of metal needles. The exact underlying mechanisms of acupuncture have not been clarified so far. Functional magnetic resonance imaging (fMRI) has become an important tool...

Three-wave mixing with three incoming waves: signal-idler coherent attenuation and gain enhancement in a parametric amplifier.

Physical review letters

Schackert F, Roy A, Hatridge M, Devoret MH, Stone AD.
PMID: 23992068
Phys Rev Lett. 2013 Aug 16;111(7):073903. doi: 10.1103/PhysRevLett.111.073903. Epub 2013 Aug 16.

We demonstrate the time-reversed process of nondegenerate three-wave parametric amplification from three distinct sources in the fully nonlinear regime using a Josephson amplifier. In the reverse process, coherent attenuation, signal and idler beams destructively interfere in the presence of...

Quantum back-action of an individual variable-strength measurement.

Science (New York, N.Y.)

Hatridge M, Shankar S, Mirrahimi M, Schackert F, Geerlings K, Brecht T, Sliwa KM, Abdo B, Frunzio L, Girvin SM, Schoelkopf RJ, Devoret MH.
PMID: 23307736
Science. 2013 Jan 11;339(6116):178-81. doi: 10.1126/science.1226897.

Measuring a quantum system can randomly perturb its state. The strength and nature of this back-action depend on the quantity that is measured. In a partial measurement performed by an ideal apparatus, quantum physics predicts that the system remains...

Establishment and Characterisation of Heterotopic Patient-Derived Xenografts for Glioblastoma.

Cancers

Meneceur S, Linge A, Meinhardt M, Hering S, Löck S, Bütof R, Krex D, Schackert G, Temme A, Baumann M, Krause M, von Neubeck C.
PMID: 32260145
Cancers (Basel). 2020 Apr 03;12(4). doi: 10.3390/cancers12040871.

Glioblastoma is an aggressive brain tumour with a patient median survival of approximately 14 months. The development of innovative treatment strategies to increase the life span and quality of life of patients is hence essential. This requires the use...

A multi-center phase II randomized clinical trial of losartan on symptomatic outpatients with COVID-19.

EClinicalMedicine

Puskarich MA, Cummins NW, Ingraham NE, Wacker DA, Reilkoff RA, Driver BE, Biros MH, Bellolio F, Chipman JG, Nelson AC, Beckman K, Langlois R, Bold T, Aliota MT, Schacker TW, Voelker HT, Murray TA, Koopmeiners JS, Tignanelli CJ.
PMID: 34195577
EClinicalMedicine. 2021 Jun 17;37:100957. doi: 10.1016/j.eclinm.2021.100957. eCollection 2021 Jul.

BACKGROUND: The SARS-CoV-2 virus enters cells via Angiotensin-converting enzyme 2 (ACE2), disrupting the renin-angiotensin-aldosterone axis, potentially contributing to lung injury. Treatment with angiotensin receptor blockers (ARBs), such as losartan, may mitigate these effects, though induction of ACE2 could increase...

Implementation of TERT promoter mutations improve prognostication of the WHO classification in meningioma.

Neuropathology and applied neurobiology

Mirian C, Grell K, Juratli TA, Sahm F, Spiegl-Kreinecker S, Peyre M, Biczok A, Tonn JC, Goutagny S, Bertero L, Maier AD, Jensen LR, Schackert G, Broholm H, Scheie D, Cahill DP, Brastianos PK, Skjøth-Rasmussen J, Fugleholm K, Ziebell M, Munch TN, Kristensen BW, Mathiesen T.
PMID: 34799864
Neuropathol Appl Neurobiol. 2021 Nov 19; doi: 10.1111/nan.12773. Epub 2021 Nov 19.

TERT promoter mutations have been associated with increased risk of recurrence in meningioma cohorts, thus a potential biomarker for aggressive phenotypes. A main purpose of refining tumour classification is better predictions on the patient level. We compiled data from...

Prospective surgical solutions in degenerative spine: spinal simulation for optimal choice of implant and targeted device development.

Innovative surgical sciences

Salchow-Gille M, Rieger B, Reinshagen C, Molcanyi M, Lemke J, Brautferger U, Sitoci-Ficici KH, Polanski W, Pinzer T, Schackert G.
PMID: 34966835
Innov Surg Sci. 2021 Apr 07;6(1):11-24. doi: 10.1515/iss-2019-1002. eCollection 2021 Mar.

OBJECTIVES: The most important goal of surgical treatment for spinal degeneration, in addition to eliminating the underlying pathology, is to preserve the biomechanically relevant structures. If degeneration destroys biomechanics, the single segment must either be surgically stabilized or functionally...

Molecular Characterization of Astrocytoma Progression Towards Secondary Glioblastomas Utilizing Patient-Matched Tumor Pairs.

Cancers

Seifert M, Schackert G, Temme A, Schröck E, Deutsch A, Klink B.
PMID: 32604718
Cancers (Basel). 2020 Jun 26;12(6). doi: 10.3390/cancers12061696.

Astrocytomas are primary human brain tumors including diffuse or anaplastic astrocytomas that develop towards secondary glioblastomas over time. However, only little is known about molecular alterations that drive this progression. We measured multi-omics profiles of patient-matched astrocytoma pairs of...

Two-mode correlation of microwave quantum noise generated by parametric down-conversion.

Physical review letters

Bergeal N, Schackert F, Frunzio L, Devoret MH.
PMID: 22540583
Phys Rev Lett. 2012 Mar 23;108(12):123902. doi: 10.1103/PhysRevLett.108.123902. Epub 2012 Mar 21.

In this Letter, we report the observation of the correlation between two modes of microwave radiation resulting from the amplification of quantum noise by the Josephson parametric converter. This process, seen from the pump, can be viewed as parametric...

Neurosurgical subspecialization: pros and cons.

Acta neurochirurgica

Schackert G, Reulen HJ.
PMID: 12820039
Acta Neurochir (Wien). 2003 May;145(5):337-40. doi: 10.1007/s00701-003-0042-1.

No abstract available.

Showing 1 to 12 of 68 entries