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A Neptune-sized transiting planet closely orbiting a 5–10-million-year-old star.

Nature

David TJ, Hillenbrand LA, Petigura EA, Carpenter JM, Crossfield IJ, Hinkley S, Ciardi DR, Howard AW, Isaacson HT, Cody AM, Schlieder JE, Beichman CA, Barenfeld SA.
PMID: 27324846
Nature. 2016 Jun 30;534(7609):658-61. doi: 10.1038/nature18293. Epub 2016 Jun 20.

Theories of the formation and early evolution of planetary systems postulate that planets are born in circumstellar disks, and undergo radial migration during and after dissipation of the dust and gas disk from which they formed. The precise ages...

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David TJ, Hillenbrand LA, Petigura EA, et al. A Neptune-sized transiting planet closely orbiting a 5–10-million-year-old star. Nature. 2016;534(7609):658-61doi: 10.1038/nature18293.
David, T. J., Hillenbrand, L. A., Petigura, E. A., Carpenter, J. M., Crossfield, I. J., Hinkley, S., Ciardi, D. R., Howard, A. W., Isaacson, H. T., Cody, A. M., Schlieder, J. E., Beichman, C. A., & Barenfeld, S. A. (2016). A Neptune-sized transiting planet closely orbiting a 5–10-million-year-old star. Nature, 534(7609), 658-61. https://doi.org/10.1038/nature18293
David, Trevor J, et al. "A Neptune-sized transiting planet closely orbiting a 5–10-million-year-old star." Nature vol. 534,7609 (2016): 658-61. doi: https://doi.org/10.1038/nature18293
David TJ, Hillenbrand LA, Petigura EA, Carpenter JM, Crossfield IJ, Hinkley S, Ciardi DR, Howard AW, Isaacson HT, Cody AM, Schlieder JE, Beichman CA, Barenfeld SA. A Neptune-sized transiting planet closely orbiting a 5–10-million-year-old star. Nature. 2016 Jun 30;534(7609):658-61. doi: 10.1038/nature18293. Epub 2016 Jun 20. PMID: 27324846.
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Recurrent DNA virus domestication leading to different parasite virulence strategies.

Science advances

Pichon A, Bézier A, Urbach S, Aury JM, Jouan V, Ravallec M, Guy J, Cousserans F, Thézé J, Gauthier J, Demettre E, Schmieder S, Wurmser F, Sibut V, Poirié M, Colinet D, da Silva C, Couloux A, Barbe V, Drezen JM, Volkoff AN.
PMID: 26702449
Sci Adv. 2015 Nov 27;1(10):e1501150. doi: 10.1126/sciadv.1501150. eCollection 2015 Nov.

Relics of ancient infections are abundant in eukaryote genomes, but little is known about how they evolve when they confer a functional benefit on their host. We show here, for the first time, that the virus-like particles shown to...

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Pichon A, Bézier A, Urbach S, et al. Recurrent DNA virus domestication leading to different parasite virulence strategies. Sci Adv. 2015;1(10):e1501150doi: 10.1126/sciadv.1501150.
Pichon, A., Bézier, A., Urbach, S., Aury, J. M., Jouan, V., Ravallec, M., Guy, J., Cousserans, F., Thézé, J., Gauthier, J., Demettre, E., Schmieder, S., Wurmser, F., Sibut, V., Poirié, M., Colinet, D., da Silva, C., Couloux, A., Barbe, V., Drezen, J. M., & Volkoff, A. N. (2015). Recurrent DNA virus domestication leading to different parasite virulence strategies. Science advances, 1(10), e1501150. https://doi.org/10.1126/sciadv.1501150
Pichon, Apolline, et al. "Recurrent DNA virus domestication leading to different parasite virulence strategies." Science advances vol. 1,10 (2015): e1501150. doi: https://doi.org/10.1126/sciadv.1501150
Pichon A, Bézier A, Urbach S, Aury JM, Jouan V, Ravallec M, Guy J, Cousserans F, Thézé J, Gauthier J, Demettre E, Schmieder S, Wurmser F, Sibut V, Poirié M, Colinet D, da Silva C, Couloux A, Barbe V, Drezen JM, Volkoff AN. Recurrent DNA virus domestication leading to different parasite virulence strategies. Sci Adv. 2015 Nov 27;1(10):e1501150. doi: 10.1126/sciadv.1501150. eCollection 2015 Nov. PMID: 26702449; PMCID: PMC4681339.
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Expertise: No Longer a Sine Qua Non for Guideline Authors?.

Hypertension (Dallas, Tex. : 1979)

Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B.
PMID: 28652465
Hypertension. 2017 Aug;70(2):235-237. doi: 10.1161/HYPERTENSIONAHA.117.09470. Epub 2017 Jun 26.

No abstract available.

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Messerli FH, Hofstetter L, Agabiti-Rosei E, et al. Expertise: No Longer a Sine Qua Non for Guideline Authors?. Hypertension. 2017;70(2):235-237doi: 10.1161/HYPERTENSIONAHA.117.09470.
Messerli, F. H., Hofstetter, L., Agabiti-Rosei, E., Burnier, M., Elliott, W. J., Franklin, S. S., Grodzicki, T., Kario, K., Kjeldsen, S. E., Kostis, J. B., Laurent, S., Leenen, F. H., Lund-Johansen, P., Mancia, G., Narkiewicz, K., Papademetriou, V., Parati, G., Poulter, N., Redon, J., Rimoldi, S. F., Ruilope, L. M., Schiffrin, E. L., Schmieder, R. E., Schwartz, A. B., Sever, P., Sowers, J. R., Staessen, J. A., Wang, J., Weber, M., & Williams, B. (2017). Expertise: No Longer a Sine Qua Non for Guideline Authors?. Hypertension (Dallas, Tex. : 1979), 70(2), 235-237. https://doi.org/10.1161/HYPERTENSIONAHA.117.09470
Messerli, Franz H, et al. "Expertise: No Longer a Sine Qua Non for Guideline Authors?." Hypertension (Dallas, Tex. : 1979) vol. 70,2 (2017): 235-237. doi: https://doi.org/10.1161/HYPERTENSIONAHA.117.09470
Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B. Expertise: No Longer a Sine Qua Non for Guideline Authors?. Hypertension. 2017 Aug;70(2):235-237. doi: 10.1161/HYPERTENSIONAHA.117.09470. Epub 2017 Jun 26. PMID: 28652465.
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Combining de novo and reference-guided assembly with scaffold_builder.

Source code for biology and medicine

Silva GG, Dutilh BE, Matthews TD, Elkins K, Schmieder R, Dinsdale EA, Edwards RA.
PMID: 24267787
Source Code Biol Med. 2013 Nov 22;8(1):23. doi: 10.1186/1751-0473-8-23.

Genome sequencing has become routine, however genome assembly still remains a challenge despite the computational advances in the last decade. In particular, the abundance of repeat elements in genomes makes it difficult to assemble them into a single complete...

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Silva GG, Dutilh BE, Matthews TD, et al. Combining de novo and reference-guided assembly with scaffold_builder. Source Code Biol Med. 2013;8(1):23doi: 10.1186/1751-0473-8-23.
Silva, G. G., Dutilh, B. E., Matthews, T. D., Elkins, K., Schmieder, R., Dinsdale, E. A., & Edwards, R. A. (2013). Combining de novo and reference-guided assembly with scaffold_builder. Source code for biology and medicine, 8(1), 23. https://doi.org/10.1186/1751-0473-8-23
Silva, Genivaldo Gz, et al. "Combining de novo and reference-guided assembly with scaffold_builder." Source code for biology and medicine vol. 8,1 (2013): 23. doi: https://doi.org/10.1186/1751-0473-8-23
Silva GG, Dutilh BE, Matthews TD, Elkins K, Schmieder R, Dinsdale EA, Edwards RA. Combining de novo and reference-guided assembly with scaffold_builder. Source Code Biol Med. 2013 Nov 22;8(1):23. doi: 10.1186/1751-0473-8-23. PMID: 24267787; PMCID: PMC4177539.
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Optimization of a precision-cut trout liver tissue slice assay as a screen for vitellogenin induction: comparison of slice incubation techniques.

Aquatic toxicology (Amsterdam, Netherlands)

Schmieder P, Tapper M, Linnum A, Denny J, Kolanczyk R, Johnson R.
PMID: 10854670
Aquat Toxicol. 2000 Jul 01;49(4):251-268. doi: 10.1016/s0166-445x(99)00087-9.

An in vitro male rainbow trout liver slice assay has been developed for long-term incubation of precision-cut slices for the detection of vitellogenin (VTG) protein induction in response to xenobiotic chemicals. The assay was optimized to allow 72 h...

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Schmieder P, Tapper M, Linnum A, et al. Optimization of a precision-cut trout liver tissue slice assay as a screen for vitellogenin induction: comparison of slice incubation techniques. Aquat Toxicol. 2000;49(4):251-268doi: 10.1016/s0166-445x(99)00087-9.
Schmieder, P., Tapper, M., Linnum, A., Denny, J., Kolanczyk, R., & Johnson, R. (2000). Optimization of a precision-cut trout liver tissue slice assay as a screen for vitellogenin induction: comparison of slice incubation techniques. Aquatic toxicology (Amsterdam, Netherlands), 49(4), 251-268. https://doi.org/10.1016/s0166-445x(99)00087-9
Schmieder, et al. "Optimization of a precision-cut trout liver tissue slice assay as a screen for vitellogenin induction: comparison of slice incubation techniques." Aquatic toxicology (Amsterdam, Netherlands) vol. 49,4 (2000): 251-268. doi: https://doi.org/10.1016/s0166-445x(99)00087-9
Schmieder P, Tapper M, Linnum A, Denny J, Kolanczyk R, Johnson R. Optimization of a precision-cut trout liver tissue slice assay as a screen for vitellogenin induction: comparison of slice incubation techniques. Aquat Toxicol. 2000 Jul 01;49(4):251-268. doi: 10.1016/s0166-445x(99)00087-9. PMID: 10854670.
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Analysis of damped and fusion processes in the 197Au+51V reaction at Elab.

Physical review. C, Nuclear physics

Butler MA, Schmieder LM, Schröder WU.
PMID: 9954423
Phys Rev C Nucl Phys. 1988 Jan;37(1):139-157. doi: 10.1103/physrevc.37.139.

No abstract available.

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Butler MA, Schmieder LM, Schröder WU. Analysis of damped and fusion processes in the 197Au+51V reaction at Elab. Phys Rev C Nucl Phys. 1988;37(1):139-157doi: 10.1103/physrevc.37.139.
Butler, M. A., Schmieder, L. M., & Schröder, W. U. (1988). Analysis of damped and fusion processes in the 197Au+51V reaction at Elab. Physical review. C, Nuclear physics, 37(1), 139-157. https://doi.org/10.1103/physrevc.37.139
Butler, et al. "Analysis of damped and fusion processes in the 197Au+51V reaction at Elab." Physical review. C, Nuclear physics vol. 37,1 (1988): 139-157. doi: https://doi.org/10.1103/physrevc.37.139
Butler MA, Schmieder LM, Schröder WU. Analysis of damped and fusion processes in the 197Au+51V reaction at Elab. Phys Rev C Nucl Phys. 1988 Jan;37(1):139-157. doi: 10.1103/physrevc.37.139. PMID: 9954423.
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Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization.

Chemical science

Kasper MA, Glanz M, Oder A, Schmieder P, von Kries JP, Hackenberger CPR.
PMID: 31341586
Chem Sci. 2019 May 16;10(25):6322-6329. doi: 10.1039/c9sc01345h. eCollection 2019 Jul 07.

In this paper, we introduce vinylphosphonites for chemoselective Staudinger-phosphonite reactions (SPhR) with azides to form vinylphosphonamidates for the subsequent modification of cysteine residues in peptides and proteins. An electron-rich alkene is turned into an electron-deficient vinylphosphonamidate, thereby inducing electrophilic...

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Kasper MA, Glanz M, Oder A, et al. Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization. Chem Sci. 2019;10(25):6322-6329doi: 10.1039/c9sc01345h.
Kasper, M. A., Glanz, M., Oder, A., Schmieder, P., von Kries, J. P., & Hackenberger, C. P. R. (2019). Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization. Chemical science, 10(25), 6322-6329. https://doi.org/10.1039/c9sc01345h
Kasper, Marc-André, et al. "Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization." Chemical science vol. 10,25 (2019): 6322-6329. doi: https://doi.org/10.1039/c9sc01345h
Kasper MA, Glanz M, Oder A, Schmieder P, von Kries JP, Hackenberger CPR. Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization. Chem Sci. 2019 May 16;10(25):6322-6329. doi: 10.1039/c9sc01345h. eCollection 2019 Jul 07. PMID: 31341586; PMCID: PMC6598645.
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Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension.

Pulmonary circulation

Sommer N, Droege F, Gamen KE, Geisthoff U, Gall H, Tello K, Richter MJ, Deubner LM, Schmiedel R, Hecker M, Spiekerkoetter E, Wirsching K, Seeger W, Ghofrani HA, Pullamsetti S.
PMID: 30260738
Pulm Circ. 2019 Apr-Jun;9(2):2045894018805406. doi: 10.1177/2045894018805406. Epub 2018 Sep 27.

Pulmonary arterial hypertension (PAH) can be found in patients suffering from a loss-of-function mutation of the gene encoding for the activin receptor-like kinase 1 (ALK-1), a bone morphogenetic protein (BMP) type 1 receptor. Interestingly, ALK-1 mutations also lead to...

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Sommer N, Droege F, Gamen KE, et al. Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension. Pulm Circ. 2018;9(2):2045894018805406doi: 10.1177/2045894018805406.
Sommer, N., Droege, F., Gamen, K. E., Geisthoff, U., Gall, H., Tello, K., Richter, M. J., Deubner, L. M., Schmiedel, R., Hecker, M., Spiekerkoetter, E., Wirsching, K., Seeger, W., Ghofrani, H. A., & Pullamsetti, S. (2019). Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension. Pulmonary circulation, 9(2), 2045894018805406. https://doi.org/10.1177/2045894018805406
Sommer, N, et al. "Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension." Pulmonary circulation vol. 9,2 (2019): 2045894018805406. doi: https://doi.org/10.1177/2045894018805406
Sommer N, Droege F, Gamen KE, Geisthoff U, Gall H, Tello K, Richter MJ, Deubner LM, Schmiedel R, Hecker M, Spiekerkoetter E, Wirsching K, Seeger W, Ghofrani HA, Pullamsetti S. Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension. Pulm Circ. 2019 Apr-Jun;9(2):2045894018805406. doi: 10.1177/2045894018805406. Epub 2018 Sep 27. PMID: 30260738; PMCID: PMC6432681.
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Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma.

Biomedical optics express

Rizzo R, Alvaro M, Danz N, Napione L, Descrovi E, Schmieder S, Sinibaldi A, Rana S, Chandrawati R, Munzert P, Schubert T, Maillart E, Anopchenko A, Rivolo P, Mascioletti A, Förster E, Sonntag F, Stevens MM, Bussolino F, Michelotti F.
PMID: 29552391
Biomed Opt Express. 2018 Jan 08;9(2):529-542. doi: 10.1364/BOE.9.000529. eCollection 2018 Feb 01.

Quantitative detection of angiogenic biomarkers provides a powerful tool to diagnose cancers in early stages and to follow its progression during therapy. Conventional tests require trained personnel, dedicated laboratory equipment and are generally time-consuming. Herein, we propose our developed...

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Rizzo R, Alvaro M, Danz N, et al. Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma. Biomed Opt Express. 2018;9(2):529-542doi: 10.1364/BOE.9.000529.
Rizzo, R., Alvaro, M., Danz, N., Napione, L., Descrovi, E., Schmieder, S., Sinibaldi, A., Rana, S., Chandrawati, R., Munzert, P., Schubert, T., Maillart, E., Anopchenko, A., Rivolo, P., Mascioletti, A., Förster, E., Sonntag, F., Stevens, M. M., Bussolino, F., & Michelotti, F. (2018). Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma. Biomedical optics express, 9(2), 529-542. https://doi.org/10.1364/BOE.9.000529
Rizzo, Riccardo, et al. "Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma." Biomedical optics express vol. 9,2 (2018): 529-542. doi: https://doi.org/10.1364/BOE.9.000529
Rizzo R, Alvaro M, Danz N, Napione L, Descrovi E, Schmieder S, Sinibaldi A, Rana S, Chandrawati R, Munzert P, Schubert T, Maillart E, Anopchenko A, Rivolo P, Mascioletti A, Förster E, Sonntag F, Stevens MM, Bussolino F, Michelotti F. Bloch surface wave enhanced biosensor for the direct detection of Angiopoietin-2 tumor biomarker in human plasma. Biomed Opt Express. 2018 Jan 08;9(2):529-542. doi: 10.1364/BOE.9.000529. eCollection 2018 Feb 01. PMID: 29552391; PMCID: PMC5854056.
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Corrigendum: Allelic variation contributes to bacterial host specificity.

Nature communications

Yue M, Han X, De Masi L, Zhu C, Ma X, Zhang J, Wu R, Schmieder R, Kaushik RS, Fraser GP, Zhao S, McDermott PF, Weill FX, Mainil JG, Arze C, Fricke WF, Edwards RA, Brisson D, Zhang NR, Rankin SC, Schifferli DM.
PMID: 28786410
Nat Commun. 2017 Aug 08;8:15229. doi: 10.1038/ncomms15229.

This corrects the article DOI: 10.1038/ncomms9754.

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Yue M, Han X, De Masi L, et al. Corrigendum: Allelic variation contributes to bacterial host specificity. Nat Commun. 2017;8:15229doi: 10.1038/ncomms15229.
Yue, M., Han, X., De Masi, L., Zhu, C., Ma, X., Zhang, J., Wu, R., Schmieder, R., Kaushik, R. S., Fraser, G. P., Zhao, S., McDermott, P. F., Weill, F. X., Mainil, J. G., Arze, C., Fricke, W. F., Edwards, R. A., Brisson, D., Zhang, N. R., Rankin, S. C., & Schifferli, D. M. (2017). Corrigendum: Allelic variation contributes to bacterial host specificity. Nature communications, 815229. https://doi.org/10.1038/ncomms15229
Yue, Min, et al. "Corrigendum: Allelic variation contributes to bacterial host specificity." Nature communications vol. 8 (2017): 15229. doi: https://doi.org/10.1038/ncomms15229
Yue M, Han X, De Masi L, Zhu C, Ma X, Zhang J, Wu R, Schmieder R, Kaushik RS, Fraser GP, Zhao S, McDermott PF, Weill FX, Mainil JG, Arze C, Fricke WF, Edwards RA, Brisson D, Zhang NR, Rankin SC, Schifferli DM. Corrigendum: Allelic variation contributes to bacterial host specificity. Nat Commun. 2017 Aug 08;8:15229. doi: 10.1038/ncomms15229. PMID: 28786410; PMCID: PMC5553040.
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Impaired coordination of nucleophile and increased hydrophobicity in the +1 subsite shift levansucrase activity towards transfructosylation.

Glycobiology

Ortiz-Soto ME, Possiel C, Görl J, Vogel A, Schmiedel R, Seibel J.
PMID: 28575294
Glycobiology. 2017 Aug 01;27(8):755-765. doi: 10.1093/glycob/cwx050.

Bacterial levansucrases produce β(2,6)-linked levan-type polysaccharides using sucrose or sucrose analogs as donor/acceptor substrates. However, the dominant reaction of Bacillus megaterium levansucrase (Bm-LS) is hydrolysis. Single domain levansucrases from Gram-positive bacteria display a wide substrate-binding pocket with open access...

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Ortiz-Soto ME, Possiel C, Görl J, et al. Impaired coordination of nucleophile and increased hydrophobicity in the +1 subsite shift levansucrase activity towards transfructosylation. Glycobiology. 2017;27(8):755-765doi: 10.1093/glycob/cwx050.
Ortiz-Soto, M. E., Possiel, C., Görl, J., Vogel, A., Schmiedel, R., & Seibel, J. (2017). Impaired coordination of nucleophile and increased hydrophobicity in the +1 subsite shift levansucrase activity towards transfructosylation. Glycobiology, 27(8), 755-765. https://doi.org/10.1093/glycob/cwx050
Ortiz-Soto, Maria Elena, et al. "Impaired coordination of nucleophile and increased hydrophobicity in the +1 subsite shift levansucrase activity towards transfructosylation." Glycobiology vol. 27,8 (2017): 755-765. doi: https://doi.org/10.1093/glycob/cwx050
Ortiz-Soto ME, Possiel C, Görl J, Vogel A, Schmiedel R, Seibel J. Impaired coordination of nucleophile and increased hydrophobicity in the +1 subsite shift levansucrase activity towards transfructosylation. Glycobiology. 2017 Aug 01;27(8):755-765. doi: 10.1093/glycob/cwx050. PMID: 28575294; PMCID: PMC5881714.
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Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields.

Structural dynamics (Melville, N.Y.)

Yang Y, Linke M, von Haimberger T, Matute R, González L, Schmieder P, Heyne K.
PMID: 26798771
Struct Dyn. 2014 Feb 05;1(1):014701. doi: 10.1063/1.4865233. eCollection 2014 Jan.

Photoisomerization of a protein bound chromophore is the basis of light sensing of many photoreceptors. We tracked Z-to-E photoisomerization of Cph1 phytochrome chromophore PCB in the Pr form in real-time. Two different phycocyanobilin (PCB) ground state geometries with different...

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Yang Y, Linke M, von Haimberger T, et al. Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields. Struct Dyn. 2014;1(1):014701doi: 10.1063/1.4865233.
Yang, Y., Linke, M., von Haimberger, T., Matute, R., González, L., Schmieder, P., & Heyne, K. (2014). Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields. Structural dynamics (Melville, N.Y.), 1(1), 014701. https://doi.org/10.1063/1.4865233
Yang, Yang, et al. "Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields." Structural dynamics (Melville, N.Y.) vol. 1,1 (2014): 014701. doi: https://doi.org/10.1063/1.4865233
Yang Y, Linke M, von Haimberger T, Matute R, González L, Schmieder P, Heyne K. Active and silent chromophore isoforms for phytochrome Pr photoisomerization: An alternative evolutionary strategy to optimize photoreaction quantum yields. Struct Dyn. 2014 Feb 05;1(1):014701. doi: 10.1063/1.4865233. eCollection 2014 Jan. PMID: 26798771; PMCID: PMC4711594.
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