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Showing 1 to 12 of 89 entries
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Selective Migration of Subpopulations of Bone Marrow Cells along an SDF-1α and ATP Gradient.

Bone marrow research

Laupheimer M, Skorska A, Große J, Tiedemann G, Steinhoff G, David R, Lux CA.
PMID: 25610653
Bone Marrow Res. 2014;2014:182645. doi: 10.1155/2014/182645. Epub 2014 Dec 31.

Both stem cell chemokine stromal cell-derived factor-1α (SDF-1α) and extracellular nucleotides such as adenosine triphosphate (ATP) are increased in ischemic myocardium. Since ATP has been reported to influence cell migration, we analysed the migratory response of bone marrow cells...

Prophylactic lithium treatment and cognitive performance in patients with a long history of bipolar illness: no simple answers in complex disease-treatment interplay.

International journal of bipolar disorders

Pfennig A, Alda M, Young T, MacQueen G, Rybakowski J, Suwalska A, Simhandl C, König B, Hajek T, O'Donovan C, Wittekind D, von Quillfeldt S, Ploch J, Sauer C, Bauer M.
PMID: 25540718
Int J Bipolar Disord. 2014 Dec 24;2:1. doi: 10.1186/s40345-014-0016-7. eCollection 2014.

Cognitive impairment in patients with bipolar disorder (BD) is not restricted to symptomatic phases. It is also present in euthymia. There is evidence of differences in the brain's structure between bipolar patients and healthy individuals, as well as changes...

Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105(+) hMSCs.

Stem cells international

Schade A, Müller P, Delyagina E, Voronina N, Skorska A, Lux C, Steinhoff G, David R.
PMID: 24799915
Stem Cells Int. 2014;2014:197154. doi: 10.1155/2014/197154. Epub 2014 Mar 31.

Genetic modifications of bone marrow derived human mesenchymal stem cells (hMSCs) using microRNAs (miRs) may be used to improve their therapeutic potential and enable innovative strategies in tissue regeneration. However, most of the studies use cultured hMSCs, although these...

Walking speed in elderly patients undergoing rehabilitation after hip replacement.

Ortopedia, traumatologia, rehabilitacja

Zak M, Skalska A.
PMID: 17611447
Ortop Traumatol Rehabil. 2005 Oct 30;7(5):543-8.

Background. Our study was undertaken to assess the impact of a structured rehabilitation regimen on walking speed in frail elderly patients recovering from hip replacement surgery, as well as to determine whether regular use of a pedal exerciser combined...

Current knowledge on the use of ultrasound measurements of fetal soft tissues for the assessment of pregnancy development.

Journal of ultrasonography

Warska A, Maliszewska A, Wnuk A, Szyszka B, Sawicki W, Cendrowski K.
PMID: 29844941
J Ultrason. 2018 Mar;18(72):50-55. doi: 10.15557/JoU.2018.0008. Epub 2018 Mar 30.

Ultrasonography, with its detailed imaging of the fetus, is very widely used in obstetrics. The primary aim of ultrasound scanning in pregnancy is to limit the risk of obstetric complications by early detection of abnormalities, such as intrauterine growth...

Effect of Simvastatin on Thrombopoiesis in Porcine Bone Marrow.

Journal of veterinary research

Snarska A, Wysocka D, Rytel L.
PMID: 30989143
J Vet Res. 2019 Mar 22;63(1):117-121. doi: 10.2478/jvetres-2019-0007. eCollection 2019 Mar.

INTRODUCTION: Statins are pharmacological agents commonly used to lower serum cholesterol level. The aim of the experiment was to investigate the effect of the statin simvastatin on thrombopoiesis in the porcine model because it is the closest to the...

Physiological condition of nestling great tits .

Conservation physiology

Glądalski M, Kaliński A, Wawrzyniak J, Bańbura M, Markowski M, Skwarska J, Bańbura J.
PMID: 30483402
Conserv Physiol. 2018 Nov 22;6(1):coy062. doi: 10.1093/conphys/coy062. eCollection 2018.

Most passerines use nests as the exclusive place to lay and incubate eggs and bring nestlings up to fledging. Nests of secondary cavity nesters, like tits, provide a moist, warm and protected habitat for reproduction of blood parasites. Offspring...

Applicability of the Protein-lipid Profile and Activity of Lactate Dehydrogenase Isoenzymes for Diagnosing Nutritional Muscular Dystrophy in Calves.

Journal of veterinary research

Żarczyńska K, Sobiech P, Snarska A, Tobolski D, Shekhar Pareek C, Bednarek D.
PMID: 30729209
J Vet Res. 2018 Dec 31;62(4):503-509. doi: 10.2478/jvetres-2018-0072. eCollection 2018 Dec.

INTRODUCTION: In calves, hyposelenosis degenerates skeletal muscles in different parts of the body. The extent of damage to muscle cells can be diagnosed by determining the activity of creatine kinase (CK), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH). The...

Investigation of atovaquone-induced spatial changes in tumour hypoxia assessed by hypoxia PET/CT in non-small cell lung cancer patients.

EJNMMI research

Bourigault P, Skwarski M, Macpherson RE, Higgins GS, McGowan DR.
PMID: 34964932
EJNMMI Res. 2021 Dec 29;11(1):130. doi: 10.1186/s13550-021-00871-x.

BACKGROUND: Tumour hypoxia promotes an aggressive tumour phenotype and enhances resistance to anticancer treatments. Following the recent observation that the mitochondrial inhibitor atovaquone increases tumour oxygenation in NSCLC, we sought to assess whether atovaquone affects tumour subregions differently depending...

Investigation of atovaquone-induced spatial changes in tumour hypoxia assessed by hypoxia PET/CT in non-small cell lung cancer patients.

EJNMMI research

Bourigault P, Skwarski M, Macpherson RE, Higgins GS, McGowan DR.
PMID: 34964932
EJNMMI Res. 2021 Dec 29;11(1):130. doi: 10.1186/s13550-021-00871-x.

BACKGROUND: Tumour hypoxia promotes an aggressive tumour phenotype and enhances resistance to anticancer treatments. Following the recent observation that the mitochondrial inhibitor atovaquone increases tumour oxygenation in NSCLC, we sought to assess whether atovaquone affects tumour subregions differently depending...

Effects of experimental lead exposure on physiological indices of nestling great tits .

Conservation physiology

Markowski M, Kaliński A, Bańbura M, Glądalski M, Wawrzyniak J, Skwarska J, Bańbura J.
PMID: 31687145
Conserv Physiol. 2019 Oct 28;7(1):coz067. doi: 10.1093/conphys/coz067. eCollection 2019.

Lead (Pb) is recognized as one of the most toxic trace elements that can induce a wide range of negative health effects in wildlife. Because the investigation of basic environment-sensitive physiological indicators is easy to perform in wild birds,...

Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism.

iScience

Bowler E, Skwarska A, Wilson JD, Ramachandran S, Bolland H, Easton A, Ostheimer C, Hwang MS, Leszczynska KB, Conway SJ, Hammond EM.
PMID: 33134898
iScience. 2020 Oct 14;23(11):101668. doi: 10.1016/j.isci.2020.101668. eCollection 2020 Nov 20.

Inhibition of the ATR kinase has emerged as a therapeutically attractive means to target cancer since the development of potent inhibitors, which are now in clinical testing. We investigated a potential link between ATR inhibition and the autophagy process...

Showing 1 to 12 of 89 entries