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Showing 1 to 12 of 37 entries
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The transition metal hexafluorides.

Dalton transactions (Cambridge, England : 2003)

Molski MJ, Seppelt K.
PMID: 19381398
Dalton Trans. 2009 May 14;(18):3379-83. doi: 10.1039/b821121c. Epub 2009 Feb 18.

The nine transition metal hexafluorides present a unique series of closely related compounds. Deviations from octahedral structures are influenced by Jahn-Teller effects and spin orbit coupling. The most pronounced chemical behaviour is the increasing electron affinity in the direction...

Some pharmacological properties of an aqueous extract of securinega virosa roots.

Pharmaceutical biology

Moshi MJ, Kapingu MC, Uiso FC, Mbwambo ZH, Mahunnah RL.
PMID: 21214465
Pharm Biol. 2000;38(3):214-21. doi: 10.1076/1388-0209(200007)3831-SFT214.

An aqueous extract of Securinega virosa is used by traditional healers in Tanga (northeastern Tanzania) as an aphrodisiac and in the treatment of impotence, which is one of the manifestations of diabetes mellitus. An aqueous extract of the roots...

Mindfulness Meditation Targets Transdiagnostic Symptoms Implicated in Stress-Related Disorders: Understanding Relationships between Changes in Mindfulness, Sleep Quality, and Physical Symptoms.

Evidence-based complementary and alternative medicine : eCAM

Greeson JM, Zarrin H, Smoski MJ, Brantley JG, Lynch TR, Webber DM, Hall MH, Suarez EC, Wolever RQ.
PMID: 29861769
Evid Based Complement Alternat Med. 2018 May 13;2018:4505191. doi: 10.1155/2018/4505191. eCollection 2018.

Mindfulness-Based Stress Reduction (MBSR) is an 8-week meditation program known to improve anxiety, depression, and psychological well-being. Other health-related effects, such as sleep quality, are less well established, as are the psychological processes associated with therapeutic change. This prospective,...

Simulation Modeling to Compare High-Throughput, Low-Iteration Optimization Strategies for Metabolic Engineering.

Frontiers in microbiology

Heinsch SC, Das SR, Smanski MJ.
PMID: 29535690
Front Microbiol. 2018 Feb 27;9:313. doi: 10.3389/fmicb.2018.00313. eCollection 2018.

Increasing the final titer of a multi-gene metabolic pathway can be viewed as a multivariate optimization problem. While numerous multivariate optimization algorithms exist, few are specifically designed to accommodate the constraints posed by genetic engineering workflows. We present a...

Screening of Plants Used as Traditional Anticancer Remedies in Mkuranga and Same Districts, Tanzania, Using Brine Shrimp Toxicity Bioassay.

Evidence-based complementary and alternative medicine : eCAM

Matata DZ, Ngassapa OD, Machumi F, Moshi MJ.
PMID: 30538758
Evid Based Complement Alternat Med. 2018 Nov 14;2018:3034612. doi: 10.1155/2018/3034612. eCollection 2018.

BACKGROUND: Inadequate specialized cancer hospitals and high costs are contributing factors that delay cancer patients from accessing health care services in Tanzania. Consequently, majority of patients are first seen by Traditional Health Practitioners (THPs) before they access specialized services....

Stereoselective semi-synthesis of the neuroprotective natural product, serofendic acid.

MedChemComm

Perusse D, Smanski MJ.
PMID: 31303993
Medchemcomm. 2019 Apr 23;10(6):951-960. doi: 10.1039/c9md00145j. eCollection 2019 Jun 01.

We have recently demonstrated a synthetic biology-enabled semi-synthesis of the potent neuroprotective compound, serofendic acid. An engineered bacterium produces

Recent Progress in Lyme Disease and Remaining Challenges.

Frontiers in medicine

Bobe JR, Jutras BL, Horn EJ, Embers ME, Bailey A, Moritz RL, Zhang Y, Soloski MJ, Ostfeld RS, Marconi RT, Aucott J, Ma'ayan A, Keesing F, Lewis K, Ben Mamoun C, Rebman AW, McClune ME, Breitschwerdt EB, Reddy PJ, Maggi R, Yang F, Nemser B, Ozcan A, Garner O, Di Carlo D, Ballard Z, Joung HA, Garcia-Romeu A, Griffiths RR, Baumgarth N, Fallon BA.
PMID: 34485323
Front Med (Lausanne). 2021 Aug 18;8:666554. doi: 10.3389/fmed.2021.666554. eCollection 2021.

Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in the United States with an estimated 476,000 cases per year. While historically, the long-term impact of Lyme disease on patients has been controversial, mounting evidence...

Is magnetic resonance imaging helpful in detecting significant prostate cancer in patients with haematospermia, normal prostate specific antigen level and digital rectal examination. A single institution, observational, and retrospective study in a United Kingdom hospital.

Central European journal of urology

Turo R, Horsu S, Calinciuc A, Smolski M, Thygesen H, Doyle G, Gulur DM, Das S, Pettersson B, Awsare N.
PMID: 29732203
Cent European J Urol. 2018;71(1):26-30. doi: 10.5173/ceju.2017.1517. Epub 2017 Jan 22.

INTRODUCTION: Haematospermia is an uncommon clinical condition that may be associated with prostate cancer. The optimal investigation of haematospermia is unknown. The aim of this study was to investigate haematospermia as a presenting symptom of significant pathology and to...

Salmonella as an Inducer of Autoimmunity.

EcoSal Plus

Soloski MJ, Metcalf ES.
PMID: 26443586
EcoSal Plus. 2007 Apr;2(2). doi: 10.1128/ecosalplus.8.8.13.

A clear etiological link has been established between infection with several gram-negative enteric pathogens, including Salmonella spp., and the incidence of reactive arthritis (ReA), an autoimmune disease that largely affects the joints. ReA is sometimes referred to as Reiter's...

Anticonvulsant activity of extracts of Diospyros fischeri stem bark.

African journal of traditional, complementary, and alternative medicines : AJTCAM

Moshi MJ, Masimba PJ, Nondo RS, Mbwambo ZH, Kapingu MC, Mohamed M, Kimbokota F.
PMID: 20162077
Afr J Tradit Complement Altern Med. 2006 Aug 28;4(1):94-8.

Evaluation of extracts of Diospyros fischeri Gurke (Ebenaceae), which is used traditionally for the treatment of epilepsy shows that the aqueous extract of the tem bark has no effect against picrotoxin induced convulsions in mice. However, an 80% ethanol...

In vivo antimalarial activity of extracts of Tanzanian medicinal plants used for the treatment of malaria.

Journal of advanced pharmaceutical technology & research

Nondo RS, Erasto P, Moshi MJ, Zacharia A, Masimba PJ, Kidukuli AW.
PMID: 27144154
J Adv Pharm Technol Res. 2016 Apr-Jun;7(2):59-63. doi: 10.4103/2231-4040.179748.

Plants used in traditional medicine have been the source of a number of currently used antimalarial medicines and continue to be a promising resource for the discovery of new classes of antimalarial compounds. The aim of this study was...

Loss of sustained activity in the ventromedial prefrontal cortex in response to repeated stress in individuals with early-life emotional abuse: implications for depression vulnerability.

Frontiers in psychology

Wang L, Paul N, Stanton SJ, Greeson JM, Smoski MJ.
PMID: 23761775
Front Psychol. 2013 Jun 04;4:320. doi: 10.3389/fpsyg.2013.00320. eCollection 2013.

Repeated psychosocial stress in early-life has significant impact on both behavior and neural function which, together, increase vulnerability to depression. However, neural mechanisms related to repeated stress remain unclear. We hypothesize that early-life stress may result in a reduced...

Showing 1 to 12 of 37 entries